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The map label for this gene is lepB [H]

Identifier: 117921466

GI number: 117921466

Start: 3632110

End: 3633027

Strand: Reverse

Name: lepB [H]

Synonym: Shewana3_3027

Alternate gene names: 117921466

Gene position: 3633027-3632110 (Counterclockwise)

Preceding gene: 117921467

Following gene: 117921465

Centisome position: 73.07

GC content: 48.69

Gene sequence:

>918_bases
ATGGCAGCCTATTTTTCCATTATTTTAGTGCTAGTCACCCTGATTTCTGGGTTGATCTGGTTAATCGATGTGCTGGTATT
TGCGCCTAAACGCCGCGAAAGCTTAGCCTTAGCCAAGGCTTCGCAGGCTAATTTAACCGAGGAAGCTGAATATAACATCA
TCCGCGAACCCACAGTGGTTGAAACCGCGCACTCCATCTTCCCTGTGATTGCCTTTGTGTTGATCCTGCGCTCGTTTATT
TACGAACCATTCCAAATTCCCTCAGGCTCTATGATGCCAACCCTGTTGGTGGGTGACTTTATTCTGGTGGAAAAGTTTAG
CTATGGCCTAAAAGATCCCGTATGGCGCACTAAACTGATTGAAACGGGCGAGCCGAAACGTGGCGATGTGATTGTGTTTA
AATATCCTGAGAACCCTCAGATTGACTACATCAAGCGCGTGGTGGGTTTACCGGGCGATCGGATTATCTACCGCAACAAG
CAGTTGATGATCCAAAAAGCCTGTGGCGCCGAGCAAACCCATTGCCCTGAGCCAGAACTGGTGGCGCGTACCGAAATCAG
CCGTGGTGATTTCAGCCAAGATGGTGTGCCATTAATTCGTTTTAAAGAGCAACTCGGTGAAGTGGCCCACGATATTTTAA
TCAATCCAAGTCGCCCCGATATGCTGGGATACTTCAAACGCGAAGGGAATTTACCTGCGGGTGAGTTCCTTGTACCCGAA
GGCCATTATTTTGCGATGGGTGACAACCGCGATAACAGTACCGACAGCCGTTTCTGGGGCTTTGTCCCTGAAGAGAATCT
TGTGGGTAAAGCGGTCGCTATCTGGATTAGTTTTGAGTTTGACCGTTCTAAAGCCGACTTCCTGCCAACTTGGGTGCCAA
GTGGTGTGCGTTTTGAACGAGTAGGTGGAATTCACTAG

Upstream 100 bases:

>100_bases
TTTTTTTAGAAATACGGTAAGTTAACTAAAGTTCGCGAGTCGAAATACAATAGTCGCTGAGTTTGGATCTTTACATTTCA
AGGCAGGAGTTCAATAAGCA

Downstream 100 bases:

>100_bases
TATGGAACCGATTAAAAATTTGCCACGTTTGTGTCGTACTTTGGGTTATGAGTTCAAGAATATTGATCTCCTCACCCAAG
CATTGACCCACAGAAGTGCG

Product: signal peptidase I

Products: NA

Alternate protein names: SPase I; Leader peptidase I [H]

Number of amino acids: Translated: 305; Mature: 304

Protein sequence:

>305_residues
MAAYFSIILVLVTLISGLIWLIDVLVFAPKRRESLALAKASQANLTEEAEYNIIREPTVVETAHSIFPVIAFVLILRSFI
YEPFQIPSGSMMPTLLVGDFILVEKFSYGLKDPVWRTKLIETGEPKRGDVIVFKYPENPQIDYIKRVVGLPGDRIIYRNK
QLMIQKACGAEQTHCPEPELVARTEISRGDFSQDGVPLIRFKEQLGEVAHDILINPSRPDMLGYFKREGNLPAGEFLVPE
GHYFAMGDNRDNSTDSRFWGFVPEENLVGKAVAIWISFEFDRSKADFLPTWVPSGVRFERVGGIH

Sequences:

>Translated_305_residues
MAAYFSIILVLVTLISGLIWLIDVLVFAPKRRESLALAKASQANLTEEAEYNIIREPTVVETAHSIFPVIAFVLILRSFI
YEPFQIPSGSMMPTLLVGDFILVEKFSYGLKDPVWRTKLIETGEPKRGDVIVFKYPENPQIDYIKRVVGLPGDRIIYRNK
QLMIQKACGAEQTHCPEPELVARTEISRGDFSQDGVPLIRFKEQLGEVAHDILINPSRPDMLGYFKREGNLPAGEFLVPE
GHYFAMGDNRDNSTDSRFWGFVPEENLVGKAVAIWISFEFDRSKADFLPTWVPSGVRFERVGGIH
>Mature_304_residues
AAYFSIILVLVTLISGLIWLIDVLVFAPKRRESLALAKASQANLTEEAEYNIIREPTVVETAHSIFPVIAFVLILRSFIY
EPFQIPSGSMMPTLLVGDFILVEKFSYGLKDPVWRTKLIETGEPKRGDVIVFKYPENPQIDYIKRVVGLPGDRIIYRNKQ
LMIQKACGAEQTHCPEPELVARTEISRGDFSQDGVPLIRFKEQLGEVAHDILINPSRPDMLGYFKREGNLPAGEFLVPEG
HYFAMGDNRDNSTDSRFWGFVPEENLVGKAVAIWISFEFDRSKADFLPTWVPSGVRFERVGGIH

Specific function: Unknown

COG id: COG0681

COG function: function code U; Signal peptidase I

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S26 family [H]

Homologues:

Organism=Escherichia coli, GI1788921, Length=332, Percent_Identity=48.4939759036145, Blast_Score=308, Evalue=3e-85,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000223
- InterPro:   IPR019758
- InterPro:   IPR019757
- InterPro:   IPR019756
- InterPro:   IPR019759
- InterPro:   IPR015927
- InterPro:   IPR011056
- InterPro:   IPR019533
- InterPro:   IPR019766 [H]

Pfam domain/function: PF00717 Peptidase_S24; PF10502 Peptidase_S26 [H]

EC number: =3.4.21.89 [H]

Molecular weight: Translated: 34506; Mature: 34375

Theoretical pI: Translated: 5.46; Mature: 5.46

Prosite motif: PS00501 SPASE_I_1 ; PS00760 SPASE_I_2 ; PS00761 SPASE_I_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAYFSIILVLVTLISGLIWLIDVLVFAPKRRESLALAKASQANLTEEAEYNIIREPTVV
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHCCCEECCCHHH
ETAHSIFPVIAFVLILRSFIYEPFQIPSGSMMPTLLVGDFILVEKFSYGLKDPVWRTKLI
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHH
ETGEPKRGDVIVFKYPENPQIDYIKRVVGLPGDRIIYRNKQLMIQKACGAEQTHCPEPEL
CCCCCCCCCEEEEECCCCCCHHHHHHHHCCCCCEEEEECHHHEEEHHCCCCCCCCCCCCC
VARTEISRGDFSQDGVPLIRFKEQLGEVAHDILINPSRPDMLGYFKREGNLPAGEFLVPE
EEHEECCCCCCCCCCCHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHCCCCCCCCEECCC
GHYFAMGDNRDNSTDSRFWGFVPEENLVGKAVAIWISFEFDRSKADFLPTWVPSGVRFER
CCEEEECCCCCCCCCCCEECCCCCCCCCCEEEEEEEEEEECCCCCCCCCCCCCCCCEECC
VGGIH
CCCCC
>Mature Secondary Structure 
AAYFSIILVLVTLISGLIWLIDVLVFAPKRRESLALAKASQANLTEEAEYNIIREPTVV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHCCCEECCCHHH
ETAHSIFPVIAFVLILRSFIYEPFQIPSGSMMPTLLVGDFILVEKFSYGLKDPVWRTKLI
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHH
ETGEPKRGDVIVFKYPENPQIDYIKRVVGLPGDRIIYRNKQLMIQKACGAEQTHCPEPEL
CCCCCCCCCEEEEECCCCCCHHHHHHHHCCCCCEEEEECHHHEEEHHCCCCCCCCCCCCC
VARTEISRGDFSQDGVPLIRFKEQLGEVAHDILINPSRPDMLGYFKREGNLPAGEFLVPE
EEHEECCCCCCCCCCCHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHCCCCCCCCEECCC
GHYFAMGDNRDNSTDSRFWGFVPEENLVGKAVAIWISFEFDRSKADFLPTWVPSGVRFER
CCEEEECCCCCCCCCCCEECCCCCCCCCCEEEEEEEEEEECCCCCCCCCCCCCCCCEECC
VGGIH
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 6311837; 9278503; 2202591; 1618816; 1546969; 8394311; 2551889; 9823901 [H]