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The map label for this gene is rnc [H]

Identifier: 117921465

GI number: 117921465

Start: 3631428

End: 3632108

Strand: Reverse

Name: rnc [H]

Synonym: Shewana3_3026

Alternate gene names: 117921465

Gene position: 3632108-3631428 (Counterclockwise)

Preceding gene: 117921466

Following gene: 117921464

Centisome position: 73.05

GC content: 46.99

Gene sequence:

>681_bases
ATGGAACCGATTAAAAATTTGCCACGTTTGTGTCGTACTTTGGGTTATGAGTTCAAGAATATTGATCTCCTCACCCAAGC
ATTGACCCACAGAAGTGCGGCAAATAAGCACAACGAGCGGTTAGAGTTTTTAGGCGATTCGATTTTATCGATAGTGATTT
CTGACGCCTTATACCATCAATTTCCTAAGGCGACTGAGGGTGACTTGAGCCGGATGCGCGCGACCTTAGTGCGTGGTGAT
ACGCTCACCTTGATTGCTAAGGCCTTTAAGCTTGGGGATTATTTATTCTTAGGCCCCGGCGAGTTAAAGAGTGGTGGTTT
TAGACGTGAGTCCATCTTGGCCGATGCGGTCGAGGCGATTATCGGCGCAATCTACTTAGATTCCGATCTTGAAGTGTGCC
GTAAGTTATTACTGCATTGGTACGCCGAGCGTTTGGCCGAGATCCAACCCGGTGTGAATCAAAAAGACGCGAAAACCTTA
CTGCAAGAATATTTACAAGGGTTAAAGAAGCCGCTACCCGATTACCAAGTAATCAACATAGAAGGCGATGCCCACGATCA
AACATTCACCGTTGAATGTCGTATAGATGACTTGAGCGAAAGCGTGATTGGCGTAGCGAGTTCGCGCCGTAAAGCCGAGC
AGATTGCCGCGGCTCAAGTATTGGAGTTACTGAAGAAATGA

Upstream 100 bases:

>100_bases
ATCTGGATTAGTTTTGAGTTTGACCGTTCTAAAGCCGACTTCCTGCCAACTTGGGTGCCAAGTGGTGTGCGTTTTGAACG
AGTAGGTGGAATTCACTAGT

Downstream 100 bases:

>100_bases
CCAAAAAAACAGACTTGCCAGCTGTCGATGCCGCTAACGCGAGCAATGAGCCGAGCTTAGATGAATTACTGGCAAGGATG
AATGCAGCGAGCGCGGCGGC

Product: ribonuclease III

Products: NA

Alternate protein names: Ribonuclease III; RNase III [H]

Number of amino acids: Translated: 226; Mature: 226

Protein sequence:

>226_residues
MEPIKNLPRLCRTLGYEFKNIDLLTQALTHRSAANKHNERLEFLGDSILSIVISDALYHQFPKATEGDLSRMRATLVRGD
TLTLIAKAFKLGDYLFLGPGELKSGGFRRESILADAVEAIIGAIYLDSDLEVCRKLLLHWYAERLAEIQPGVNQKDAKTL
LQEYLQGLKKPLPDYQVINIEGDAHDQTFTVECRIDDLSESVIGVASSRRKAEQIAAAQVLELLKK

Sequences:

>Translated_226_residues
MEPIKNLPRLCRTLGYEFKNIDLLTQALTHRSAANKHNERLEFLGDSILSIVISDALYHQFPKATEGDLSRMRATLVRGD
TLTLIAKAFKLGDYLFLGPGELKSGGFRRESILADAVEAIIGAIYLDSDLEVCRKLLLHWYAERLAEIQPGVNQKDAKTL
LQEYLQGLKKPLPDYQVINIEGDAHDQTFTVECRIDDLSESVIGVASSRRKAEQIAAAQVLELLKK
>Mature_226_residues
MEPIKNLPRLCRTLGYEFKNIDLLTQALTHRSAANKHNERLEFLGDSILSIVISDALYHQFPKATEGDLSRMRATLVRGD
TLTLIAKAFKLGDYLFLGPGELKSGGFRRESILADAVEAIIGAIYLDSDLEVCRKLLLHWYAERLAEIQPGVNQKDAKTL
LQEYLQGLKKPLPDYQVINIEGDAHDQTFTVECRIDDLSESVIGVASSRRKAEQIAAAQVLELLKK

Specific function: Digests double-stranded RNA. Involved in the processing of ribosomal RNA precursors and of some mRNAs [H]

COG id: COG0571

COG function: function code K; dsRNA-specific ribonuclease

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RNase III domain [H]

Homologues:

Organism=Homo sapiens, GI155030236, Length=220, Percent_Identity=30, Blast_Score=93, Evalue=2e-19,
Organism=Homo sapiens, GI155030234, Length=220, Percent_Identity=30, Blast_Score=93, Evalue=2e-19,
Organism=Escherichia coli, GI1788920, Length=211, Percent_Identity=64.9289099526066, Blast_Score=285, Evalue=2e-78,
Organism=Caenorhabditis elegans, GI193202651, Length=189, Percent_Identity=33.3333333333333, Blast_Score=116, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI17506883, Length=189, Percent_Identity=33.3333333333333, Blast_Score=116, Evalue=1e-26,
Organism=Drosophila melanogaster, GI17137682, Length=234, Percent_Identity=31.1965811965812, Blast_Score=93, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001159
- InterPro:   IPR014720
- InterPro:   IPR000999
- InterPro:   IPR011907 [H]

Pfam domain/function: PF00035 dsrm; PF00636 Ribonuclease_3 [H]

EC number: =3.1.26.3 [H]

Molecular weight: Translated: 25307; Mature: 25307

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: PS50137 DS_RBD ; PS00517 RNASE_3_1 ; PS50142 RNASE_3_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEPIKNLPRLCRTLGYEFKNIDLLTQALTHRSAANKHNERLEFLGDSILSIVISDALYHQ
CCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FPKATEGDLSRMRATLVRGDTLTLIAKAFKLGDYLFLGPGELKSGGFRRESILADAVEAI
CCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCEEEECCCCCCCCCCHHHHHHHHHHHHH
IGAIYLDSDLEVCRKLLLHWYAERLAEIQPGVNQKDAKTLLQEYLQGLKKPLPDYQVINI
HHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEE
EGDAHDQTFTVECRIDDLSESVIGVASSRRKAEQIAAAQVLELLKK
CCCCCCCEEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MEPIKNLPRLCRTLGYEFKNIDLLTQALTHRSAANKHNERLEFLGDSILSIVISDALYHQ
CCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FPKATEGDLSRMRATLVRGDTLTLIAKAFKLGDYLFLGPGELKSGGFRRESILADAVEAI
CCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCEEEECCCCCCCCCCHHHHHHHHHHHHH
IGAIYLDSDLEVCRKLLLHWYAERLAEIQPGVNQKDAKTLLQEYLQGLKKPLPDYQVINI
HHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEE
EGDAHDQTFTVECRIDDLSESVIGVASSRRKAEQIAAAQVLELLKK
CCCCCCCEEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA