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The map label for this gene is era [H]

Identifier: 117921464

GI number: 117921464

Start: 3630412

End: 3631431

Strand: Reverse

Name: era [H]

Synonym: Shewana3_3025

Alternate gene names: 117921464

Gene position: 3631431-3630412 (Counterclockwise)

Preceding gene: 117921465

Following gene: 117921463

Centisome position: 73.03

GC content: 50.59

Gene sequence:

>1020_bases
ATGACCAAAAAAACAGACTTGCCAGCTGTCGATGCCGCTAACGCGAGCAATGAGCCGAGCTTAGATGAATTACTGGCAAG
GATGAATGCAGCGAGCGCGGCGGCGCCGTCTGTTCACTATGATGTGACCTACTGTGGCATGGTGGCCATTATTGGCCGCC
CTAACGTGGGTAAATCGACCCTGCTGAACCGTTTGCTTGGGCAAAAGATCAGTATTACCTCGAAAAAGCCGCAAACGACG
CGTCATCGCATTATGGGTATCCATACCGATGGCCCGCGTCAAATCGTGTTTATCGACACGCCTGGCCTGCATATTGAAGA
GCAGCGTGCGATTAACCGTCTGATGAACCGCGCGGCGGCGAGCTCGCTTGCCGATGTGTCTATGGTGATTTTTGTGGTCG
ATGGTATGACATGGACCGCCGATGATGAAATGGTGTTAAGCAAACTTCGCCGTGGCGGTGAAGAACGTAAAACCGTGTTA
GCCATCAACAAAGTCGATAATATCAAAGACAAAGAAGCCCTTTTCCCCTATTTGGAAGAAGTGGCCAAGAAGTATCCCTT
CGATGAAATTCTGCCGATTTCTGCCAGCAAAGGCACCAACGTAAAGCGCATTTTAGAGATGGCGGCAGAGTCGCTGCCCG
AGAATCCGTTCTTCTTTCCTGAAGATTATGTGACTGACCGTTCGCAGCGTTTTATGGCCTCTGAAATTGTCCGTGAAAAA
CTGATGCGCTTCCTCGGTGATGAATTGCCCTACGATGCGACGGTTGAAATCGAGCAGTTTAAGATGATGGAAAACGGCGT
TTATCAAATCAATGCCCTGATCCTCGTCGAGCGTGAAGGCCAAAAGCGGATGGTGATTGGTAGCAAAGGCGAGCGCATTC
GTACCATCGCTACGCAAGCGCGCCTCGATATGGAAACCTTGTTTGATAACAAAGTGTTCCTCGAGGTGTGGGTAAAGGTC
AAATCCGGTTGGGCCGATGATGAGCGCGCCCTGCGAAGCTTAGGTTACGGTGACGATTAA

Upstream 100 bases:

>100_bases
GTCGTATAGATGACTTGAGCGAAAGCGTGATTGGCGTAGCGAGTTCGCGCCGTAAAGCCGAGCAGATTGCCGCGGCTCAA
GTATTGGAGTTACTGAAGAA

Downstream 100 bases:

>100_bases
TCGTTACTGATAATAGGCCGAGCCTGATCATGAACGAGCGCGCAGACCGATGAAACGGGGCTATGTTTTGCATCATCGCC
CTTACCGGGAGTCTAGCGCG

Product: GTP-binding protein Era

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 339; Mature: 338

Protein sequence:

>339_residues
MTKKTDLPAVDAANASNEPSLDELLARMNAASAAAPSVHYDVTYCGMVAIIGRPNVGKSTLLNRLLGQKISITSKKPQTT
RHRIMGIHTDGPRQIVFIDTPGLHIEEQRAINRLMNRAAASSLADVSMVIFVVDGMTWTADDEMVLSKLRRGGEERKTVL
AINKVDNIKDKEALFPYLEEVAKKYPFDEILPISASKGTNVKRILEMAAESLPENPFFFPEDYVTDRSQRFMASEIVREK
LMRFLGDELPYDATVEIEQFKMMENGVYQINALILVEREGQKRMVIGSKGERIRTIATQARLDMETLFDNKVFLEVWVKV
KSGWADDERALRSLGYGDD

Sequences:

>Translated_339_residues
MTKKTDLPAVDAANASNEPSLDELLARMNAASAAAPSVHYDVTYCGMVAIIGRPNVGKSTLLNRLLGQKISITSKKPQTT
RHRIMGIHTDGPRQIVFIDTPGLHIEEQRAINRLMNRAAASSLADVSMVIFVVDGMTWTADDEMVLSKLRRGGEERKTVL
AINKVDNIKDKEALFPYLEEVAKKYPFDEILPISASKGTNVKRILEMAAESLPENPFFFPEDYVTDRSQRFMASEIVREK
LMRFLGDELPYDATVEIEQFKMMENGVYQINALILVEREGQKRMVIGSKGERIRTIATQARLDMETLFDNKVFLEVWVKV
KSGWADDERALRSLGYGDD
>Mature_338_residues
TKKTDLPAVDAANASNEPSLDELLARMNAASAAAPSVHYDVTYCGMVAIIGRPNVGKSTLLNRLLGQKISITSKKPQTTR
HRIMGIHTDGPRQIVFIDTPGLHIEEQRAINRLMNRAAASSLADVSMVIFVVDGMTWTADDEMVLSKLRRGGEERKTVLA
INKVDNIKDKEALFPYLEEVAKKYPFDEILPISASKGTNVKRILEMAAESLPENPFFFPEDYVTDRSQRFMASEIVREKL
MRFLGDELPYDATVEIEQFKMMENGVYQINALILVEREGQKRMVIGSKGERIRTIATQARLDMETLFDNKVFLEVWVKVK
SGWADDERALRSLGYGDD

Specific function: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism [H]

COG id: COG1159

COG function: function code R; GTPase

Gene ontology:

Cell location: Cytoplasm. Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH type-2 domain [H]

Homologues:

Organism=Homo sapiens, GI24307899, Length=325, Percent_Identity=25.5384615384615, Blast_Score=88, Evalue=1e-17,
Organism=Escherichia coli, GI1788919, Length=299, Percent_Identity=65.8862876254181, Blast_Score=414, Evalue=1e-117,
Organism=Escherichia coli, GI87082120, Length=161, Percent_Identity=32.9192546583851, Blast_Score=71, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24646434, Length=303, Percent_Identity=25.7425742574257, Blast_Score=98, Evalue=8e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005662
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR009019
- InterPro:   IPR004044
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF07650 KH_2; PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 38133; Mature: 38002

Theoretical pI: Translated: 5.85; Mature: 5.85

Prosite motif: PS50823 KH_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKKTDLPAVDAANASNEPSLDELLARMNAASAAAPSVHYDVTYCGMVAIIGRPNVGKST
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEHHHEEEEEEECCCCCCHHH
LLNRLLGQKISITSKKPQTTRHRIMGIHTDGPRQIVFIDTPGLHIEEQRAINRLMNRAAA
HHHHHHCCEEEECCCCCCCCCCEEEEEECCCCCEEEEEECCCCCCHHHHHHHHHHHHHHH
SSLADVSMVIFVVDGMTWTADDEMVLSKLRRGGEERKTVLAINKVDNIKDKEALFPYLEE
HHHHHHEEEEEEECCCEECCCHHHHHHHHHCCCCHHEEEEEEECCCCCCCHHHHHHHHHH
VAKKYPFDEILPISASKGTNVKRILEMAAESLPENPFFFPEDYVTDRSQRFMASEIVREK
HHHHCCCCCEEECCCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHCCHHHHHHHHHHHHHH
LMRFLGDELPYDATVEIEQFKMMENGVYQINALILVEREGQKRMVIGSKGERIRTIATQA
HHHHHCCCCCCCCEEHHHHHHHHHCCCEEEEEEEEEEECCCEEEEECCCCCHHHHHHHHH
RLDMETLFDNKVFLEVWVKVKSGWADDERALRSLGYGDD
HHHHHHHHCCCEEEEEEEHHHCCCCCHHHHHHHCCCCCC
>Mature Secondary Structure 
TKKTDLPAVDAANASNEPSLDELLARMNAASAAAPSVHYDVTYCGMVAIIGRPNVGKST
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEHHHEEEEEEECCCCCCHHH
LLNRLLGQKISITSKKPQTTRHRIMGIHTDGPRQIVFIDTPGLHIEEQRAINRLMNRAAA
HHHHHHCCEEEECCCCCCCCCCEEEEEECCCCCEEEEEECCCCCCHHHHHHHHHHHHHHH
SSLADVSMVIFVVDGMTWTADDEMVLSKLRRGGEERKTVLAINKVDNIKDKEALFPYLEE
HHHHHHEEEEEEECCCEECCCHHHHHHHHHCCCCHHEEEEEEECCCCCCCHHHHHHHHHH
VAKKYPFDEILPISASKGTNVKRILEMAAESLPENPFFFPEDYVTDRSQRFMASEIVREK
HHHHCCCCCEEECCCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHCCHHHHHHHHHHHHHH
LMRFLGDELPYDATVEIEQFKMMENGVYQINALILVEREGQKRMVIGSKGERIRTIATQA
HHHHHCCCCCCCCEEHHHHHHHHHCCCEEEEEEEEEEECCCEEEEECCCCCHHHHHHHHH
RLDMETLFDNKVFLEVWVKVKSGWADDERALRSLGYGDD
HHHHHHHHCCCEEEEEEEHHHCCCCCHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11248100 [H]