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The map label for this gene is aceB [H]

Identifier: 117921383

GI number: 117921383

Start: 3533376

End: 3535025

Strand: Reverse

Name: aceB [H]

Synonym: Shewana3_2943

Alternate gene names: 117921383

Gene position: 3535025-3533376 (Counterclockwise)

Preceding gene: 117921385

Following gene: 117921382

Centisome position: 71.1

GC content: 48.91

Gene sequence:

>1650_bases
ATGACGGAACACACTTTAGGTGAACAGCAATTGAATTCGACACAGAATAAGGCCACTGCGAATGGCACTCTGGCCTTAGT
GGGAAATACCATACCAGGGCAGGAGGTGATTTTTACCGAAGGCGCGCTGGCGTTGCTTGAGTCACTTTGCCGTGAATTTG
CGACAGAAGTGCCCACCTTACTCGCCAAACGTAAAGATAGACAAGCGCGTATTGATAAAGGGGCTTTGCCTGACTTTTTA
CCCGAGACTCGCGCTATTCGTGACGGGGCATGGAAGATCCGTGGCATTCCGAATGACTTACTCGATCGCCGTGTTGAAAT
CACCGGTCCCGTCGAACGTAAGATGGTGATCAATGCACTCAATGCCAATGCCAAAGTGTTTATGGCGGATTTTGAAGACT
CCTTAGCACCGAGCTGGCAGAAAGTGGTTGAAGGTCAGATTAACCTGCGTGATGCCGTGCGCGGTGAGATTGAATACACA
GCGCCTGAAACTGGTAAACATTACAAGCTAGGCCCAAATCCTGCGGTATTAATCTGTCGTGTGCGTGGTCTGCACTTAAA
AGAGAAGCACGTTGAATTTAACCAGCAGTCCATCCCCGGCGCGTTATTCGACTTTGCGATGTACTTTTACCATAACTATC
GCCAATTGCTGGCGAAGGGCAGTGGTCCTTACTTCTATATTCCTAAACTCGAGAGCCATATCGAAGCGCGTTGGTGGGCA
AAAGTGTTTGCTTTTGTTGAAGAAAGATTCTGCCTACAGCCTGGCACAATCAAATGTACTTGTTTGATTGAGACCTTACC
CGCGGTGTTTGAAATGGACGAAATTCTCTATGAATTACGCTCAAACATTGTCGCGCTCAACTGTGGTCGTTGGGACTATA
TCTTCAGCTATATCAAAACATTAAAGCGTCATAGCGACCGCGTTTTACCGGATCGCCAAGCGGTGACCATGGATACGCCT
TTCTTAAGCGCCTATTCAAGACTGCTGATCAAAACCTGCCATAAACGTGGCGCACTGGCGATGGGTGGCATGGCGGCCTT
TATTCCAGCGAAGGATCCTGCTCAGAACGAAACCGTGTTGCAACGAGTGCGTAAGGACAAAGAGCTTGAGGCGCGTAATG
GCCACGATGGGACTTGGGTCGCTCACCCGGGTCTTGCGGATACGGCGATGGGGATCTTTAACGAATACATAGGCCAAGAT
CATCAAAACCAATTGCATATCACCCGTGATGTGGATGCACCGATCCTCGCCGCAGAGTTATTAAAACCCTGTGATGGCGA
GCGTACAGAGCAAGGGATGCGCCTGAATATTCGCATCGCACTGCAATACCTTGAGGCGTGGATCAGTGGCAACGGTTGTG
TACCGATTTACGGATTAATGGAAGATGCGGCAACGGCTGAAATCTCCCGCGCCTCGATTTGGCAATGGATCCAACATGGC
AAGTCACTCTCAAACGGCAAACCCGTCACTAAACAATTGTTTAAGGACATGCTAGTGGAAGAGTTAGCGAATGTGAAAAA
AGAAGTGGGCAGTGACAGATTCACCCACGGCAAATTTACCCAAGCAGCGGTATTGCTTGAGGATATTACCACTTCGGATG
AGTTGGTTGATTTCTTAACCTTACCCGGTTACGAGATGCTAACGGCTTAA

Upstream 100 bases:

>100_bases
TTTGAATGTTTTTAGGTGAATGTTTGTACATGTTACTCATGTCTTTGCTGGTAACGAGTCGTAAACGAGCAAAAGGTTAG
CCTCTTGGGAGGGCGAGAAG

Downstream 100 bases:

>100_bases
TGATTAGCGTTTTAATGCTGTAACACTGAATGCGTTTACATGGAATGCGTTATGGCGGTCAAACCGCCAATTAAACCAAT
GGGCAGGGTGAGGCTGTGGG

Product: malate synthase

Products: NA

Alternate protein names: MSA [H]

Number of amino acids: Translated: 549; Mature: 548

Protein sequence:

>549_residues
MTEHTLGEQQLNSTQNKATANGTLALVGNTIPGQEVIFTEGALALLESLCREFATEVPTLLAKRKDRQARIDKGALPDFL
PETRAIRDGAWKIRGIPNDLLDRRVEITGPVERKMVINALNANAKVFMADFEDSLAPSWQKVVEGQINLRDAVRGEIEYT
APETGKHYKLGPNPAVLICRVRGLHLKEKHVEFNQQSIPGALFDFAMYFYHNYRQLLAKGSGPYFYIPKLESHIEARWWA
KVFAFVEERFCLQPGTIKCTCLIETLPAVFEMDEILYELRSNIVALNCGRWDYIFSYIKTLKRHSDRVLPDRQAVTMDTP
FLSAYSRLLIKTCHKRGALAMGGMAAFIPAKDPAQNETVLQRVRKDKELEARNGHDGTWVAHPGLADTAMGIFNEYIGQD
HQNQLHITRDVDAPILAAELLKPCDGERTEQGMRLNIRIALQYLEAWISGNGCVPIYGLMEDAATAEISRASIWQWIQHG
KSLSNGKPVTKQLFKDMLVEELANVKKEVGSDRFTHGKFTQAAVLLEDITTSDELVDFLTLPGYEMLTA

Sequences:

>Translated_549_residues
MTEHTLGEQQLNSTQNKATANGTLALVGNTIPGQEVIFTEGALALLESLCREFATEVPTLLAKRKDRQARIDKGALPDFL
PETRAIRDGAWKIRGIPNDLLDRRVEITGPVERKMVINALNANAKVFMADFEDSLAPSWQKVVEGQINLRDAVRGEIEYT
APETGKHYKLGPNPAVLICRVRGLHLKEKHVEFNQQSIPGALFDFAMYFYHNYRQLLAKGSGPYFYIPKLESHIEARWWA
KVFAFVEERFCLQPGTIKCTCLIETLPAVFEMDEILYELRSNIVALNCGRWDYIFSYIKTLKRHSDRVLPDRQAVTMDTP
FLSAYSRLLIKTCHKRGALAMGGMAAFIPAKDPAQNETVLQRVRKDKELEARNGHDGTWVAHPGLADTAMGIFNEYIGQD
HQNQLHITRDVDAPILAAELLKPCDGERTEQGMRLNIRIALQYLEAWISGNGCVPIYGLMEDAATAEISRASIWQWIQHG
KSLSNGKPVTKQLFKDMLVEELANVKKEVGSDRFTHGKFTQAAVLLEDITTSDELVDFLTLPGYEMLTA
>Mature_548_residues
TEHTLGEQQLNSTQNKATANGTLALVGNTIPGQEVIFTEGALALLESLCREFATEVPTLLAKRKDRQARIDKGALPDFLP
ETRAIRDGAWKIRGIPNDLLDRRVEITGPVERKMVINALNANAKVFMADFEDSLAPSWQKVVEGQINLRDAVRGEIEYTA
PETGKHYKLGPNPAVLICRVRGLHLKEKHVEFNQQSIPGALFDFAMYFYHNYRQLLAKGSGPYFYIPKLESHIEARWWAK
VFAFVEERFCLQPGTIKCTCLIETLPAVFEMDEILYELRSNIVALNCGRWDYIFSYIKTLKRHSDRVLPDRQAVTMDTPF
LSAYSRLLIKTCHKRGALAMGGMAAFIPAKDPAQNETVLQRVRKDKELEARNGHDGTWVAHPGLADTAMGIFNEYIGQDH
QNQLHITRDVDAPILAAELLKPCDGERTEQGMRLNIRIALQYLEAWISGNGCVPIYGLMEDAATAEISRASIWQWIQHGK
SLSNGKPVTKQLFKDMLVEELANVKKEVGSDRFTHGKFTQAAVLLEDITTSDELVDFLTLPGYEMLTA

Specific function: Glyoxylate bypass; second step. [C]

COG id: COG2225

COG function: function code C; Malate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the malate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1790444, Length=531, Percent_Identity=68.361581920904, Blast_Score=758, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17561814, Length=529, Percent_Identity=49.3383742911153, Blast_Score=498, Evalue=1e-141,
Organism=Caenorhabditis elegans, GI71982926, Length=421, Percent_Identity=51.3064133016627, Blast_Score=410, Evalue=1e-114,
Organism=Saccharomyces cerevisiae, GI6324212, Length=523, Percent_Identity=45.3154875717017, Blast_Score=441, Evalue=1e-124,
Organism=Saccharomyces cerevisiae, GI6322222, Length=518, Percent_Identity=44.980694980695, Blast_Score=440, Evalue=1e-124,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011076
- InterPro:   IPR006252
- InterPro:   IPR001465
- InterPro:   IPR019830 [H]

Pfam domain/function: PF01274 Malate_synthase [H]

EC number: =2.3.3.9 [H]

Molecular weight: Translated: 61761; Mature: 61629

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEHTLGEQQLNSTQNKATANGTLALVGNTIPGQEVIFTEGALALLESLCREFATEVPTL
CCCCCCCHHHHHCCCCCCCCCCEEEEEECCCCCCEEEEECCHHHHHHHHHHHHHHHHHHH
LAKRKDRQARIDKGALPDFLPETRAIRDGAWKIRGIPNDLLDRRVEITGPVERKMVINAL
HHHCCHHHHHCCCCCCCCCCCCHHHHHCCCEEECCCCHHHHHCEEEECCCHHHHHHHHEE
NANAKVFMADFEDSLAPSWQKVVEGQINLRDAVRGEIEYTAPETGKHYKLGPNPAVLICR
CCCCEEEEECCCHHCCCCHHHHHCCCCCHHHHHCCCEEECCCCCCCCEECCCCCEEEEEE
VRGLHLKEKHVEFNQQSIPGALFDFAMYFYHNYRQLLAKGSGPYFYIPKLESHIEARWWA
ECCCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHH
KVFAFVEERFCLQPGTIKCTCLIETLPAVFEMDEILYELRSNIVALNCGRWDYIFSYIKT
HHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHH
LKRHSDRVLPDRQAVTMDTPFLSAYSRLLIKTCHKRGALAMGGMAAFIPAKDPAQNETVL
HHHHCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHCCCEEECCEEEECCCCCCCCCHHHH
QRVRKDKELEARNGHDGTWVAHPGLADTAMGIFNEYIGQDHQNQLHITRDVDAPILAAEL
HHHHCCCCCCCCCCCCCCEEECCCCHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHH
LKPCDGERTEQGMRLNIRIALQYLEAWISGNGCVPIYGLMEDAATAEISRASIWQWIQHG
HCCCCCCCCCCCCEEEHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCC
KSLSNGKPVTKQLFKDMLVEELANVKKEVGSDRFTHGKFTQAAVLLEDITTSDELVDFLT
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHH
LPGYEMLTA
CCCHHHHCC
>Mature Secondary Structure 
TEHTLGEQQLNSTQNKATANGTLALVGNTIPGQEVIFTEGALALLESLCREFATEVPTL
CCCCCCHHHHHCCCCCCCCCCEEEEEECCCCCCEEEEECCHHHHHHHHHHHHHHHHHHH
LAKRKDRQARIDKGALPDFLPETRAIRDGAWKIRGIPNDLLDRRVEITGPVERKMVINAL
HHHCCHHHHHCCCCCCCCCCCCHHHHHCCCEEECCCCHHHHHCEEEECCCHHHHHHHHEE
NANAKVFMADFEDSLAPSWQKVVEGQINLRDAVRGEIEYTAPETGKHYKLGPNPAVLICR
CCCCEEEEECCCHHCCCCHHHHHCCCCCHHHHHCCCEEECCCCCCCCEECCCCCEEEEEE
VRGLHLKEKHVEFNQQSIPGALFDFAMYFYHNYRQLLAKGSGPYFYIPKLESHIEARWWA
ECCCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHH
KVFAFVEERFCLQPGTIKCTCLIETLPAVFEMDEILYELRSNIVALNCGRWDYIFSYIKT
HHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHH
LKRHSDRVLPDRQAVTMDTPFLSAYSRLLIKTCHKRGALAMGGMAAFIPAKDPAQNETVL
HHHHCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHCCCEEECCEEEECCCCCCCCCHHHH
QRVRKDKELEARNGHDGTWVAHPGLADTAMGIFNEYIGQDHQNQLHITRDVDAPILAAEL
HHHHCCCCCCCCCCCCCCEEECCCCHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHH
LKPCDGERTEQGMRLNIRIALQYLEAWISGNGCVPIYGLMEDAATAEISRASIWQWIQHG
HCCCCCCCCCCCCEEEHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCC
KSLSNGKPVTKQLFKDMLVEELANVKKEVGSDRFTHGKFTQAAVLLEDITTSDELVDFLT
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHH
LPGYEMLTA
CCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3050899; 3060852; 8265357; 9278503 [H]