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The map label for this gene is frr [H]

Identifier: 117921253

GI number: 117921253

Start: 3359428

End: 3359985

Strand: Reverse

Name: frr [H]

Synonym: Shewana3_2812

Alternate gene names: 117921253

Gene position: 3359985-3359428 (Counterclockwise)

Preceding gene: 117921254

Following gene: 117921252

Centisome position: 67.58

GC content: 48.21

Gene sequence:

>558_bases
GTGATTGCAGATATTAAAAAAGATGCTCAAGAGCGCATGGGTAAATGCGTAGAAGCGACTAAGAACCAAATGGCGAAAGT
ACGTACTGGTCGTGCACACCCAAGCTTACTGGACTCTATCCAAGTGTCTTACTACGGCACTATGACCCCGCTGAACCAAG
TGGCTAACGTGGGGATTGAAGATGCGCGCACCCTGTCTGTGACTGTGTTCGACCGTAGTGCAATCCAAGCGGTTGAGAAA
GCAATTATGAGCTCTGACCTTGGCTTAAACCCAATGTCAGCGGGCGCAACCTTACGTATTCCATTACCCGCACTGACTGA
AGAACGTCGTAAAGACTTCATCAAAGTGGTTCGTGCAGAAGCCGAAGGCGGCCGTGTGGCGATTCGTAACGTACGCCGTG
ACGCGATTTCTGAAGTGAAGAAGCTCGAAAAAGCCAAAGAATGTACTGAAGACGATGTTCGCCGCTTTGAAGACGAAGTG
CAAAAGTTCACCGATGCTCACATTAAGAAGGTCGATGAGATTTTAGCGGCCAAAGAAATTGAGTTGATGGAAGTCTAA

Upstream 100 bases:

>100_bases
TGAACAAACCAGGTGCACTGCGCCGCGTGGTCATGGGTGAAGAAGAAGGCACATTGATCAAAGCGAAATAAGTTTTTAAT
GACCAAGAAGGACATTTAAC

Downstream 100 bases:

>100_bases
TCTCAGGCGCTATAAGCTAGAGTTGCTACGCCGTGTAGGGGTATACTACACGGCGTTTGTCTATTTTAAAGGGTTGTAAT
AGATGTCATCCACAGTGGAA

Product: ribosome recycling factor

Products: NA

Alternate protein names: RRF; Ribosome-releasing factor [H]

Number of amino acids: Translated: 185; Mature: 185

Protein sequence:

>185_residues
MIADIKKDAQERMGKCVEATKNQMAKVRTGRAHPSLLDSIQVSYYGTMTPLNQVANVGIEDARTLSVTVFDRSAIQAVEK
AIMSSDLGLNPMSAGATLRIPLPALTEERRKDFIKVVRAEAEGGRVAIRNVRRDAISEVKKLEKAKECTEDDVRRFEDEV
QKFTDAHIKKVDEILAAKEIELMEV

Sequences:

>Translated_185_residues
MIADIKKDAQERMGKCVEATKNQMAKVRTGRAHPSLLDSIQVSYYGTMTPLNQVANVGIEDARTLSVTVFDRSAIQAVEK
AIMSSDLGLNPMSAGATLRIPLPALTEERRKDFIKVVRAEAEGGRVAIRNVRRDAISEVKKLEKAKECTEDDVRRFEDEV
QKFTDAHIKKVDEILAAKEIELMEV
>Mature_185_residues
MIADIKKDAQERMGKCVEATKNQMAKVRTGRAHPSLLDSIQVSYYGTMTPLNQVANVGIEDARTLSVTVFDRSAIQAVEK
AIMSSDLGLNPMSAGATLRIPLPALTEERRKDFIKVVRAEAEGGRVAIRNVRRDAISEVKKLEKAKECTEDDVRRFEDEV
QKFTDAHIKKVDEILAAKEIELMEV

Specific function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another [H]

COG id: COG0233

COG function: function code J; Ribosome recycling factor

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RRF family [H]

Homologues:

Organism=Homo sapiens, GI20270317, Length=179, Percent_Identity=28.4916201117318, Blast_Score=77, Evalue=9e-15,
Organism=Homo sapiens, GI291042689, Length=150, Percent_Identity=28.6666666666667, Blast_Score=66, Evalue=2e-11,
Organism=Escherichia coli, GI1786368, Length=184, Percent_Identity=66.304347826087, Blast_Score=244, Evalue=2e-66,
Organism=Drosophila melanogaster, GI24661488, Length=173, Percent_Identity=30.635838150289, Blast_Score=72, Evalue=3e-13,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002661
- InterPro:   IPR015998 [H]

Pfam domain/function: PF01765 RRF [H]

EC number: NA

Molecular weight: Translated: 20629; Mature: 20629

Theoretical pI: Translated: 7.42; Mature: 7.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIADIKKDAQERMGKCVEATKNQMAKVRTGRAHPSLLDSIQVSYYGTMTPLNQVANVGIE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCHHHHHHHCCCC
DARTLSVTVFDRSAIQAVEKAIMSSDLGLNPMSAGATLRIPLPALTEERRKDFIKVVRAE
CCCEEEEEEECHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHC
AEGGRVAIRNVRRDAISEVKKLEKAKECTEDDVRRFEDEVQKFTDAHIKKVDEILAAKEI
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELMEV
HHHCC
>Mature Secondary Structure
MIADIKKDAQERMGKCVEATKNQMAKVRTGRAHPSLLDSIQVSYYGTMTPLNQVANVGIE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCHHHHHHHCCCC
DARTLSVTVFDRSAIQAVEKAIMSSDLGLNPMSAGATLRIPLPALTEERRKDFIKVVRAE
CCCEEEEEEECHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHC
AEGGRVAIRNVRRDAISEVKKLEKAKECTEDDVRRFEDEVQKFTDAHIKKVDEILAAKEI
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELMEV
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA