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The map label for this gene is pyrH [H]

Identifier: 117921254

GI number: 117921254

Start: 3360015

End: 3360743

Strand: Reverse

Name: pyrH [H]

Synonym: Shewana3_2813

Alternate gene names: 117921254

Gene position: 3360743-3360015 (Counterclockwise)

Preceding gene: 117921255

Following gene: 117921253

Centisome position: 67.59

GC content: 48.29

Gene sequence:

>729_bases
ATGAGCACCAATCCAAAACCTGCATTTAGACGCATTCTTCTAAAATTAAGTGGCGAGGCACTGATGGGCGACGAAGGCTT
CGGCATCGACCCTAAAGTGTTAGATCGCATGGCTCAAGAAGTGAAAGAGCTGGTAGAGTTAGGCATTCAGGTGGGGGTGG
TCATTGGTGGTGGTAATCTATTTCGCGGTGAAGGCCTAGCAAAAGCTGGCATGAACCGTGTGGTGGGCGATCACATGGGT
ATGCTGGCAACGGTTATGAACGGCTTGGCCATGCGTGATGCCCTGCACCGTGCCTATGTTAATGCTCGTCTGATGTCGGC
AATCCCGTTAAAAGGGGTGTGTGACGACTACAATTGGGCTGAGGCTATCAGCTTATTAAAATCAGGCCGTGTAGTGATTT
TTGCTGCGGGTACTGGTAACCCATTCTGCACTACCGATTCTGCGGCTTGCTTACGCGGCATTGAAATCGAAGCAGAAGTC
GTGCTAAAAGGCACTAAAGTTGACGGCGTTTATTCTGACGACCCGATGAAAAATCCAGAAGCAGTGAAGTACGATGAATT
ATCGTACACTGAAGTACTGGACAAAGAATTAAAAGTAATGGACTTAGCAGCCTTTACGATGGCGCGTGATCATGACATGC
CAATCCTAGTATTCAACATGAACAAACCAGGTGCACTGCGCCGCGTGGTCATGGGTGAAGAAGAAGGCACATTGATCAAA
GCGAAATAA

Upstream 100 bases:

>100_bases
GCTCAAATCGCCGCTTCTAAAAAGGCTTAATCGCCAACGCTAAATACCCCCAAGACCGCAGCAATGGCTGCGGTCTTGTT
ATGACCAGGATATAAAAATT

Downstream 100 bases:

>100_bases
GTTTTTAATGACCAAGAAGGACATTTAACGTGATTGCAGATATTAAAAAAGATGCTCAAGAGCGCATGGGTAAATGCGTA
GAAGCGACTAAGAACCAAAT

Product: uridylate kinase

Products: NA

Alternate protein names: UK; Uridine monophosphate kinase; UMP kinase; UMPK [H]

Number of amino acids: Translated: 242; Mature: 241

Protein sequence:

>242_residues
MSTNPKPAFRRILLKLSGEALMGDEGFGIDPKVLDRMAQEVKELVELGIQVGVVIGGGNLFRGEGLAKAGMNRVVGDHMG
MLATVMNGLAMRDALHRAYVNARLMSAIPLKGVCDDYNWAEAISLLKSGRVVIFAAGTGNPFCTTDSAACLRGIEIEAEV
VLKGTKVDGVYSDDPMKNPEAVKYDELSYTEVLDKELKVMDLAAFTMARDHDMPILVFNMNKPGALRRVVMGEEEGTLIK
AK

Sequences:

>Translated_242_residues
MSTNPKPAFRRILLKLSGEALMGDEGFGIDPKVLDRMAQEVKELVELGIQVGVVIGGGNLFRGEGLAKAGMNRVVGDHMG
MLATVMNGLAMRDALHRAYVNARLMSAIPLKGVCDDYNWAEAISLLKSGRVVIFAAGTGNPFCTTDSAACLRGIEIEAEV
VLKGTKVDGVYSDDPMKNPEAVKYDELSYTEVLDKELKVMDLAAFTMARDHDMPILVFNMNKPGALRRVVMGEEEGTLIK
AK
>Mature_241_residues
STNPKPAFRRILLKLSGEALMGDEGFGIDPKVLDRMAQEVKELVELGIQVGVVIGGGNLFRGEGLAKAGMNRVVGDHMGM
LATVMNGLAMRDALHRAYVNARLMSAIPLKGVCDDYNWAEAISLLKSGRVVIFAAGTGNPFCTTDSAACLRGIEIEAEVV
LKGTKVDGVYSDDPMKNPEAVKYDELSYTEVLDKELKVMDLAAFTMARDHDMPILVFNMNKPGALRRVVMGEEEGTLIKA
K

Specific function: Catalyzes the reversible phosphorylation of UMP to UDP [H]

COG id: COG0528

COG function: function code F; Uridylate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UMP kinase family [H]

Homologues:

Organism=Escherichia coli, GI1786367, Length=239, Percent_Identity=82.8451882845188, Blast_Score=414, Evalue=1e-117,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001048
- InterPro:   IPR011817
- InterPro:   IPR015963 [H]

Pfam domain/function: PF00696 AA_kinase [H]

EC number: =2.7.4.22 [H]

Molecular weight: Translated: 26221; Mature: 26090

Theoretical pI: Translated: 5.43; Mature: 5.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
6.2 %Met     (Translated Protein)
7.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
5.8 %Met     (Mature Protein)
7.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTNPKPAFRRILLKLSGEALMGDEGFGIDPKVLDRMAQEVKELVELGIQVGVVIGGGNL
CCCCCCHHHHHHHHHHCCCEEECCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEECCCE
FRGEGLAKAGMNRVVGDHMGMLATVMNGLAMRDALHRAYVNARLMSAIPLKGVCDDYNWA
ECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHH
EAISLLKSGRVVIFAAGTGNPFCTTDSAACLRGIEIEAEVVLKGTKVDGVYSDDPMKNPE
HHHHHHHCCCEEEEEECCCCCCCCCCHHHHHHCCEEEEEEEEEECEECCEECCCCCCCCC
AVKYDELSYTEVLDKELKVMDLAAFTMARDHDMPILVFNMNKPGALRRVVMGEEEGTLIK
CCEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHEEECCCCCCEEE
AK
CC
>Mature Secondary Structure 
STNPKPAFRRILLKLSGEALMGDEGFGIDPKVLDRMAQEVKELVELGIQVGVVIGGGNL
CCCCCHHHHHHHHHHCCCEEECCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEECCCE
FRGEGLAKAGMNRVVGDHMGMLATVMNGLAMRDALHRAYVNARLMSAIPLKGVCDDYNWA
ECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHH
EAISLLKSGRVVIFAAGTGNPFCTTDSAACLRGIEIEAEVVLKGTKVDGVYSDDPMKNPE
HHHHHHHCCCEEEEEECCCCCCCCCCHHHHHHCCEEEEEEEEEECEECCEECCCCCCCCC
AVKYDELSYTEVLDKELKVMDLAAFTMARDHDMPILVFNMNKPGALRRVVMGEEEGTLIK
CCEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHEEECCCCCCEEE
AK
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA