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The map label for this gene is metA [H]

Identifier: 117921213

GI number: 117921213

Start: 3311879

End: 3312820

Strand: Reverse

Name: metA [H]

Synonym: Shewana3_2772

Alternate gene names: 117921213

Gene position: 3312820-3311879 (Counterclockwise)

Preceding gene: 117921214

Following gene: 117921212

Centisome position: 66.63

GC content: 48.83

Gene sequence:

>942_bases
ATGCCAGTTAAAATTCCAGATCATCTGCCTGCAGCAGGGATTTTAGAATCTGAAAATATTTTCGTAATGTCCGAGACCCG
GGCTGCCAATCAAGACATCAGACCGATGAAGGTGCTGATCCTGAATCTGATGCCCAATAAAATCGAGACAGAAACCCAGC
TTCTACGCCTATTAGGTAACACGCCTTTGCAGGTGGATGTCGATTTACTGCGTATTCATGATAAAGAGTCGAAGCACACC
TCAATTGATCATATGAACACCTTCTACCGTGATTTTGAGGACGTGCGCCATAAAAACTACGACGGCCTGATCATCACGGG
CGCGCCCCTTGGGCAAATCGATTTCGAAGAGGTTACTTACTGGGATCATATCCGCGAGATTATCGATTGGTCACAGCAGC
ATGTTACGTCAGTGCTATTCCTCTGCTGGGCGGCGCACGCTGGGCTTTATCATCTCTACGGCTTAAATCGGAAAATCCTG
CAGCAAAAGCGTTCTGGGGTGTTTGTGCATCGCCGCACCTGCCAACATTTCCCGCTGCTGCGCGGATTCGATGATGAGTT
CTTTGCGCCGCATTCCCGCTTTGCCGAGATGGATATCGAGGAACTTAAACAGCATTCTGAGCTGCAGGTACTGGCACAAT
CCGATGAGGCAGGAGCCTACTTAGTCCTCAGTCGTAACAATCGCAACCTGTTTGTGATGGGGCACCCCGAATACCAAAAA
TCTACCTTAAACGATGAATATCATCGGGATTTAGCGCAGGGATTAAATCCCAATGTGCCGCAAAACTATTATCGTAACGA
CGATCCCAAGGACGATGCCATTGCCCGTTGGCATAGTCATGGCAGCCTGCTCGTCAGCAACTGGCTCAACTATTACGTTT
ACCAATTAACGCCCTATGACTTAAGCGATATGTCTGCTGTCACGCCGTGGGAATCGCAGTAG

Upstream 100 bases:

>100_bases
GACGATACTGCTTGAGAAAGTCGGTCGCTAATTTGTTTGCTCTTTGATGAGTGGCATACGCGCGCCGGAACCTTTGATTG
TTGAATAGAAGAGGCGCGGT

Downstream 100 bases:

>100_bases
TTTCCTCTACGCATTCGGCTTAGCACTATTTTAGTGTTTGTTCTGGCGTTTATTTTACTGCTCTCTTAAATCGAGTGGCT
TTGGCTAACCAAGGTCACTC

Product: homoserine O-succinyltransferase

Products: NA

Alternate protein names: Homoserine O-transsuccinylase; HTS [H]

Number of amino acids: Translated: 313; Mature: 312

Protein sequence:

>313_residues
MPVKIPDHLPAAGILESENIFVMSETRAANQDIRPMKVLILNLMPNKIETETQLLRLLGNTPLQVDVDLLRIHDKESKHT
SIDHMNTFYRDFEDVRHKNYDGLIITGAPLGQIDFEEVTYWDHIREIIDWSQQHVTSVLFLCWAAHAGLYHLYGLNRKIL
QQKRSGVFVHRRTCQHFPLLRGFDDEFFAPHSRFAEMDIEELKQHSELQVLAQSDEAGAYLVLSRNNRNLFVMGHPEYQK
STLNDEYHRDLAQGLNPNVPQNYYRNDDPKDDAIARWHSHGSLLVSNWLNYYVYQLTPYDLSDMSAVTPWESQ

Sequences:

>Translated_313_residues
MPVKIPDHLPAAGILESENIFVMSETRAANQDIRPMKVLILNLMPNKIETETQLLRLLGNTPLQVDVDLLRIHDKESKHT
SIDHMNTFYRDFEDVRHKNYDGLIITGAPLGQIDFEEVTYWDHIREIIDWSQQHVTSVLFLCWAAHAGLYHLYGLNRKIL
QQKRSGVFVHRRTCQHFPLLRGFDDEFFAPHSRFAEMDIEELKQHSELQVLAQSDEAGAYLVLSRNNRNLFVMGHPEYQK
STLNDEYHRDLAQGLNPNVPQNYYRNDDPKDDAIARWHSHGSLLVSNWLNYYVYQLTPYDLSDMSAVTPWESQ
>Mature_312_residues
PVKIPDHLPAAGILESENIFVMSETRAANQDIRPMKVLILNLMPNKIETETQLLRLLGNTPLQVDVDLLRIHDKESKHTS
IDHMNTFYRDFEDVRHKNYDGLIITGAPLGQIDFEEVTYWDHIREIIDWSQQHVTSVLFLCWAAHAGLYHLYGLNRKILQ
QKRSGVFVHRRTCQHFPLLRGFDDEFFAPHSRFAEMDIEELKQHSELQVLAQSDEAGAYLVLSRNNRNLFVMGHPEYQKS
TLNDEYHRDLAQGLNPNVPQNYYRNDDPKDDAIARWHSHGSLLVSNWLNYYVYQLTPYDLSDMSAVTPWESQ

Specific function: Methionine biosynthesis; HTS variant; first step. [C]

COG id: COG1897

COG function: function code E; Homoserine trans-succinylase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HTS family [H]

Homologues:

Organism=Escherichia coli, GI1790443, Length=305, Percent_Identity=52.7868852459016, Blast_Score=362, Evalue=1e-101,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005697
- ProDom:   PD037892 [H]

Pfam domain/function: PF04204 HTS [H]

EC number: =2.3.1.46 [H]

Molecular weight: Translated: 36513; Mature: 36381

Theoretical pI: Translated: 5.92; Mature: 5.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVKIPDHLPAAGILESENIFVMSETRAANQDIRPMKVLILNLMPNKIETETQLLRLLGN
CCCCCCCCCCCCCEECCCCEEEEECCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHCC
TPLQVDVDLLRIHDKESKHTSIDHMNTFYRDFEDVRHKNYDGLIITGAPLGQIDFEEVTY
CCCEEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCHHHHHH
WDHIREIIDWSQQHVTSVLFLCWAAHAGLYHLYGLNRKILQQKRSGVFVHRRTCQHFPLL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCHHHHHHHHCCCEEEHHHHHHCCHH
RGFDDEFFAPHSRFAEMDIEELKQHSELQVLAQSDEAGAYLVLSRNNRNLFVMGHPEYQK
CCCCHHHCCCCHHHHHCCHHHHHCCCCEEEEEECCCCCEEEEEEECCCEEEEEECCCHHH
STLNDEYHRDLAQGLNPNVPQNYYRNDDPKDDAIARWHSHGSLLVSNWLNYYVYQLTPYD
HHCCHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHCEEEEEECCCC
LSDMSAVTPWESQ
CCCCCCCCCCCCC
>Mature Secondary Structure 
PVKIPDHLPAAGILESENIFVMSETRAANQDIRPMKVLILNLMPNKIETETQLLRLLGN
CCCCCCCCCCCCEECCCCEEEEECCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHCC
TPLQVDVDLLRIHDKESKHTSIDHMNTFYRDFEDVRHKNYDGLIITGAPLGQIDFEEVTY
CCCEEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCHHHHHH
WDHIREIIDWSQQHVTSVLFLCWAAHAGLYHLYGLNRKILQQKRSGVFVHRRTCQHFPLL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCHHHHHHHHCCCEEEHHHHHHCCHH
RGFDDEFFAPHSRFAEMDIEELKQHSELQVLAQSDEAGAYLVLSRNNRNLFVMGHPEYQK
CCCCHHHCCCCHHHHHCCHHHHHCCCCEEEEEECCCCCEEEEEEECCCEEEEEECCCHHH
STLNDEYHRDLAQGLNPNVPQNYYRNDDPKDDAIARWHSHGSLLVSNWLNYYVYQLTPYD
HHCCHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHCEEEEEECCCC
LSDMSAVTPWESQ
CCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA