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The map label for this gene is atoB [H]

Identifier: 117921212

GI number: 117921212

Start: 3310297

End: 3311487

Strand: Reverse

Name: atoB [H]

Synonym: Shewana3_2771

Alternate gene names: 117921212

Gene position: 3311487-3310297 (Counterclockwise)

Preceding gene: 117921213

Following gene: 117921211

Centisome position: 66.6

GC content: 53.74

Gene sequence:

>1191_bases
ATGAGTACTGAACAATTTAACCAAGAGATCGTTATTGTTGCCGCTAAACGCACCCCAATGGGTGGCTTTCAAGGCAGTTT
GTCTGGCGTAATGTCTCCGAGCTTAGCGGCCACCGCCATCAAAGCCCTGTTAGCCGATACCCAAGTTGCGCCTGACAAGG
TCGATGAAGTGTTAATGGGCTGCGTATTACCTGCGGGTCTGGGCCAAGCGCCTGCGCGTCAGGCGACCTTAGGTGCAGGT
TTACCCCTGTCTGTAGGTGCTACGACCGTAAACAAAGTCTGTGGCTCTGGGATGAAAACCGTGATGCTTGCCCACGATTT
ACTTAAAGCGGGCAGTGCTAAGTTGGTGGTTGCGGGCGGTATGGAAAGTATGAGCCAAGCCCCTTACTTGCTGGATAAAG
CGCGCGCTGGCATGCGTATGGGCCATGGCAAGGTATTAGATCATATGTTCCTCGACGGTTTAGAAGATGCCTACACTGGC
GGCGCCATGGGCACATTCGCCCAGAAAACTGCCGACGAATATGGTTTAACCCGCGAGCAAATGGATGCGTTTGCTTTAAG
CTCGCTCGAAAAAGCCAATGCCGCGATTAACTCTGGTGCCTTCAAGGCGGAAATTGTACCTGTGACTGTGAGCGATCGCC
GTGGTGATGTGACTGTCGATACCGATGAGCAGCCAGGTAACGCCCGCCCTGAAAAAATCCCCGCACTGCGCCCAGCTTTT
GCCAAAGACGGCACTATTACGGCGGCAAACTCAAGCTCTATTTCCGATGGTGCGGCGGCGCTGATGCTAACCACGCGCGC
CAATGCCGAGCAGTTAGGCTTAACAGTGCTGGCCACCATCAAGGGGCACACAACCCATGCACAGGAGCCATCACTCTTTA
CCACGGCACCCGTTGGCGCTATGGCAAAACTGCTGAGCAATGTCGGCTGGTCTAAGGATGAGGTTGACCTGTTCGAAATC
AACGAAGCCTTTGCCATGGTGACTATGCTGGCCGTTTCTGAATTAGGTTTAGATATGGCAAAAGTGAACGTGAACGGTGG
CGCCTGCGCCTTAGGTCATCCTATCGGTTGCTCGGGTGCACGTTTGCTGGTGACCTTAATCCATGCACTTAAAGCCCGTG
GGCTTAAGCGTGGCGTAGCCTCACTCTGTATCGGTGGTGGTGAAGCTACCGCTATGGCTATCGAAGTCTAA

Upstream 100 bases:

>100_bases
CTTGCTTTACGTTCGCGTAAACGTCAGAGTGGTTTCATTGTCACTATTTATCCGCCGCTGGCGAGTGTTACCGCCAAGGC
ACATTTAGCTTGGAGTCCCC

Downstream 100 bases:

>100_bases
TCAAAGGCTTAATCGCGAATAAAGGCAAAACAATCAACAAGACCAAGACTGAGCTGGCAAGGGCAAACATCCCGCTGAGG
ATAAACATAATATCGCACCG

Product: acetyl-CoA acetyltransferases

Products: NA

Alternate protein names: Acetoacetyl-CoA thiolase [H]

Number of amino acids: Translated: 396; Mature: 395

Protein sequence:

>396_residues
MSTEQFNQEIVIVAAKRTPMGGFQGSLSGVMSPSLAATAIKALLADTQVAPDKVDEVLMGCVLPAGLGQAPARQATLGAG
LPLSVGATTVNKVCGSGMKTVMLAHDLLKAGSAKLVVAGGMESMSQAPYLLDKARAGMRMGHGKVLDHMFLDGLEDAYTG
GAMGTFAQKTADEYGLTREQMDAFALSSLEKANAAINSGAFKAEIVPVTVSDRRGDVTVDTDEQPGNARPEKIPALRPAF
AKDGTITAANSSSISDGAAALMLTTRANAEQLGLTVLATIKGHTTHAQEPSLFTTAPVGAMAKLLSNVGWSKDEVDLFEI
NEAFAMVTMLAVSELGLDMAKVNVNGGACALGHPIGCSGARLLVTLIHALKARGLKRGVASLCIGGGEATAMAIEV

Sequences:

>Translated_396_residues
MSTEQFNQEIVIVAAKRTPMGGFQGSLSGVMSPSLAATAIKALLADTQVAPDKVDEVLMGCVLPAGLGQAPARQATLGAG
LPLSVGATTVNKVCGSGMKTVMLAHDLLKAGSAKLVVAGGMESMSQAPYLLDKARAGMRMGHGKVLDHMFLDGLEDAYTG
GAMGTFAQKTADEYGLTREQMDAFALSSLEKANAAINSGAFKAEIVPVTVSDRRGDVTVDTDEQPGNARPEKIPALRPAF
AKDGTITAANSSSISDGAAALMLTTRANAEQLGLTVLATIKGHTTHAQEPSLFTTAPVGAMAKLLSNVGWSKDEVDLFEI
NEAFAMVTMLAVSELGLDMAKVNVNGGACALGHPIGCSGARLLVTLIHALKARGLKRGVASLCIGGGEATAMAIEV
>Mature_395_residues
STEQFNQEIVIVAAKRTPMGGFQGSLSGVMSPSLAATAIKALLADTQVAPDKVDEVLMGCVLPAGLGQAPARQATLGAGL
PLSVGATTVNKVCGSGMKTVMLAHDLLKAGSAKLVVAGGMESMSQAPYLLDKARAGMRMGHGKVLDHMFLDGLEDAYTGG
AMGTFAQKTADEYGLTREQMDAFALSSLEKANAAINSGAFKAEIVPVTVSDRRGDVTVDTDEQPGNARPEKIPALRPAFA
KDGTITAANSSSISDGAAALMLTTRANAEQLGLTVLATIKGHTTHAQEPSLFTTAPVGAMAKLLSNVGWSKDEVDLFEIN
EAFAMVTMLAVSELGLDMAKVNVNGGACALGHPIGCSGARLLVTLIHALKARGLKRGVASLCIGGGEATAMAIEV

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thiolase family [H]

Homologues:

Organism=Homo sapiens, GI148539872, Length=389, Percent_Identity=46.0154241645244, Blast_Score=328, Evalue=5e-90,
Organism=Homo sapiens, GI4557237, Length=390, Percent_Identity=45.1282051282051, Blast_Score=313, Evalue=1e-85,
Organism=Homo sapiens, GI167614485, Length=391, Percent_Identity=37.8516624040921, Blast_Score=261, Evalue=1e-69,
Organism=Homo sapiens, GI4501853, Length=406, Percent_Identity=37.192118226601, Blast_Score=226, Evalue=3e-59,
Organism=Homo sapiens, GI4504327, Length=423, Percent_Identity=29.7872340425532, Blast_Score=149, Evalue=6e-36,
Organism=Homo sapiens, GI194353979, Length=398, Percent_Identity=29.8994974874372, Blast_Score=132, Evalue=7e-31,
Organism=Escherichia coli, GI87082165, Length=389, Percent_Identity=47.3007712082262, Blast_Score=349, Evalue=2e-97,
Organism=Escherichia coli, GI1788554, Length=390, Percent_Identity=52.5641025641026, Blast_Score=344, Evalue=6e-96,
Organism=Escherichia coli, GI1787663, Length=402, Percent_Identity=38.0597014925373, Blast_Score=233, Evalue=1e-62,
Organism=Escherichia coli, GI48994986, Length=404, Percent_Identity=37.1287128712871, Blast_Score=209, Evalue=4e-55,
Organism=Escherichia coli, GI1788683, Length=403, Percent_Identity=29.0322580645161, Blast_Score=151, Evalue=6e-38,
Organism=Caenorhabditis elegans, GI25147385, Length=389, Percent_Identity=43.4447300771208, Blast_Score=311, Evalue=5e-85,
Organism=Caenorhabditis elegans, GI17535921, Length=391, Percent_Identity=41.1764705882353, Blast_Score=286, Evalue=2e-77,
Organism=Caenorhabditis elegans, GI133906874, Length=387, Percent_Identity=38.5012919896641, Blast_Score=273, Evalue=9e-74,
Organism=Caenorhabditis elegans, GI17535917, Length=393, Percent_Identity=35.3689567430025, Blast_Score=201, Evalue=6e-52,
Organism=Caenorhabditis elegans, GI17551802, Length=422, Percent_Identity=30.0947867298578, Blast_Score=160, Evalue=1e-39,
Organism=Saccharomyces cerevisiae, GI6325229, Length=395, Percent_Identity=47.3417721518987, Blast_Score=332, Evalue=7e-92,
Organism=Saccharomyces cerevisiae, GI6322031, Length=395, Percent_Identity=34.1772151898734, Blast_Score=201, Evalue=2e-52,
Organism=Drosophila melanogaster, GI24655093, Length=388, Percent_Identity=46.3917525773196, Blast_Score=341, Evalue=4e-94,
Organism=Drosophila melanogaster, GI24640423, Length=389, Percent_Identity=43.7017994858612, Blast_Score=298, Evalue=3e-81,
Organism=Drosophila melanogaster, GI17648125, Length=396, Percent_Identity=37.1212121212121, Blast_Score=239, Evalue=2e-63,
Organism=Drosophila melanogaster, GI17137578, Length=427, Percent_Identity=31.1475409836066, Blast_Score=160, Evalue=1e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002155
- InterPro:   IPR016039
- InterPro:   IPR016038
- InterPro:   IPR020615
- InterPro:   IPR020610
- InterPro:   IPR020617
- InterPro:   IPR020613
- InterPro:   IPR020616 [H]

Pfam domain/function: PF02803 Thiolase_C; PF00108 Thiolase_N [H]

EC number: =2.3.1.9 [H]

Molecular weight: Translated: 40638; Mature: 40507

Theoretical pI: Translated: 6.17; Mature: 6.17

Prosite motif: PS00098 THIOLASE_1 ; PS00099 THIOLASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTEQFNQEIVIVAAKRTPMGGFQGSLSGVMSPSLAATAIKALLADTQVAPDKVDEVLMG
CCCCCCCCEEEEEEECCCCCCCCCCCHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHH
CVLPAGLGQAPARQATLGAGLPLSVGATTVNKVCGSGMKTVMLAHDLLKAGSAKLVVAGG
HHHCCCCCCCCCCHHHCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEECC
MESMSQAPYLLDKARAGMRMGHGKVLDHMFLDGLEDAYTGGAMGTFAQKTADEYGLTREQ
HHHHHCCCHHHHHHHHCHHCCCHHHHHHHHHHCHHHHHCCCCHHHHHHHHHHHHCCCHHH
MDAFALSSLEKANAAINSGAFKAEIVPVTVSDRRGDVTVDTDEQPGNARPEKIPALRPAF
HHHHHHHHHHHHHHHHCCCCEEEEEEEEEECCCCCCEEEECCCCCCCCCCCCCCCCCCCC
AKDGTITAANSSSISDGAAALMLTTRANAEQLGLTVLATIKGHTTHAQEPSLFTTAPVGA
CCCCEEEECCCCCCCCCCEEEEEEECCCHHHHCEEEEEEECCCCCCCCCCCCEEECCHHH
MAKLLSNVGWSKDEVDLFEINEAFAMVTMLAVSELGLDMAKVNVNGGACALGHPIGCSGA
HHHHHHHCCCCCCCCEEEEHHHHHHHHHHHHHHHHCCEEEEEECCCCEEECCCCCCCCHH
RLLVTLIHALKARGLKRGVASLCIGGGEATAMAIEV
HHHHHHHHHHHHHHHHHHHHHHEECCCCEEEEEEEC
>Mature Secondary Structure 
STEQFNQEIVIVAAKRTPMGGFQGSLSGVMSPSLAATAIKALLADTQVAPDKVDEVLMG
CCCCCCCEEEEEEECCCCCCCCCCCHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHH
CVLPAGLGQAPARQATLGAGLPLSVGATTVNKVCGSGMKTVMLAHDLLKAGSAKLVVAGG
HHHCCCCCCCCCCHHHCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEECC
MESMSQAPYLLDKARAGMRMGHGKVLDHMFLDGLEDAYTGGAMGTFAQKTADEYGLTREQ
HHHHHCCCHHHHHHHHCHHCCCHHHHHHHHHHCHHHHHCCCCHHHHHHHHHHHHCCCHHH
MDAFALSSLEKANAAINSGAFKAEIVPVTVSDRRGDVTVDTDEQPGNARPEKIPALRPAF
HHHHHHHHHHHHHHHHCCCCEEEEEEEEEECCCCCCEEEECCCCCCCCCCCCCCCCCCCC
AKDGTITAANSSSISDGAAALMLTTRANAEQLGLTVLATIKGHTTHAQEPSLFTTAPVGA
CCCCEEEECCCCCCCCCCEEEEEEECCCHHHHCEEEEEEECCCCCCCCCCCCEEECCHHH
MAKLLSNVGWSKDEVDLFEINEAFAMVTMLAVSELGLDMAKVNVNGGACALGHPIGCSGA
HHHHHHHCCCCCCCCEEEEHHHHHHHHHHHHHHHHCCEEEEEECCCCEEECCCCCCCCHH
RLLVTLIHALKARGLKRGVASLCIGGGEATAMAIEV
HHHHHHHHHHHHHHHHHHHHHHEECCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]