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The map label for this gene is crt [H]

Identifier: 117921209

GI number: 117921209

Start: 3306503

End: 3307276

Strand: Reverse

Name: crt [H]

Synonym: Shewana3_2768

Alternate gene names: 117921209

Gene position: 3307276-3306503 (Counterclockwise)

Preceding gene: 117921210

Following gene: 117921208

Centisome position: 66.52

GC content: 54.39

Gene sequence:

>774_bases
ATGGAATATTTAGTTGAGCGTATCGAAGGCCACACGGCGATTCTGACGATGAATAATCCGCCGGCCAACACTTGGACCGC
CCAGAGTTTGCAGGCGCTCAAGGCCAAAGTGCTGGAGCTTAATGCCAACAAGGACATTTATGCGCTGGTGTTAACTGGCG
AGGGTAACAAGTTTTTCTCCGCCGGTGCCGATTTAAAACTCTTTAGCGACGGTGATAAGGGCAATGCGGCGAGCATGGCA
AAACACTTTGGCGAAGCATTTGAAACCTTAAGCCAGTTCCGCGGCGTGTCGATTGCCGCCATTAACGGTTATGCCATGGG
CGGCGGCTTAGAAGTCGCGCTGGCCTGTGATATTCGTATCGCCGAGACCCAAGCTGTGATGGCACTGCCTGAGGCCACCG
TTGGCCTGCTGCCCTGTGCGGGTGGCACCCAAAACCTGACCGCTTTAGTGGGCGAAGGTTGGGCGAAGCGGATGATCCTC
TGCGGTGAGCGGGTGAATGCTGCCCAAGCGCTGAATTTGCGTTTAGTCGAGGAAGTGGTCGAAACGGGTGAAGCCTTAAA
TGCGGCGATTGCACTGGCCGCCAAAGTGGCGAATCAGAGCCCAAGCAGCGTAACTGCCTGTAAGACACTCATCCAAGCAG
GGCGTCAAATGCCGCGCAGCCAAGCCTTACCGATAGAGCGTGAACTGTTTGTCGGATTGTTCGATACTGAAGATCAGGCC
GAAGGCGTGAACGCGTTTTTGGAAAAACGTAAAGCTGATTGGAAGAACCGCTAA

Upstream 100 bases:

>100_bases
CGTTTACTCGACGAAAATGCCGGACAAATCCTCTAAGCTGCCCAGATGGGACTATAGGATTTGGCGATAACCGATTGGAA
ATATAAGGGAGCCGAAACAG

Downstream 100 bases:

>100_bases
TGACAAATTTAGTAGATAAGGCTGCACACACGTCCACCACACAAAATGTGGTTTTTCAAACCTTAGCCACCGCCTCAGGT
AAATTAGTTGGGGTGGTGAC

Product: enoyl-CoA hydratase

Products: NA

Alternate protein names: Crotonase [H]

Number of amino acids: Translated: 257; Mature: 257

Protein sequence:

>257_residues
MEYLVERIEGHTAILTMNNPPANTWTAQSLQALKAKVLELNANKDIYALVLTGEGNKFFSAGADLKLFSDGDKGNAASMA
KHFGEAFETLSQFRGVSIAAINGYAMGGGLEVALACDIRIAETQAVMALPEATVGLLPCAGGTQNLTALVGEGWAKRMIL
CGERVNAAQALNLRLVEEVVETGEALNAAIALAAKVANQSPSSVTACKTLIQAGRQMPRSQALPIERELFVGLFDTEDQA
EGVNAFLEKRKADWKNR

Sequences:

>Translated_257_residues
MEYLVERIEGHTAILTMNNPPANTWTAQSLQALKAKVLELNANKDIYALVLTGEGNKFFSAGADLKLFSDGDKGNAASMA
KHFGEAFETLSQFRGVSIAAINGYAMGGGLEVALACDIRIAETQAVMALPEATVGLLPCAGGTQNLTALVGEGWAKRMIL
CGERVNAAQALNLRLVEEVVETGEALNAAIALAAKVANQSPSSVTACKTLIQAGRQMPRSQALPIERELFVGLFDTEDQA
EGVNAFLEKRKADWKNR
>Mature_257_residues
MEYLVERIEGHTAILTMNNPPANTWTAQSLQALKAKVLELNANKDIYALVLTGEGNKFFSAGADLKLFSDGDKGNAASMA
KHFGEAFETLSQFRGVSIAAINGYAMGGGLEVALACDIRIAETQAVMALPEATVGLLPCAGGTQNLTALVGEGWAKRMIL
CGERVNAAQALNLRLVEEVVETGEALNAAIALAAKVANQSPSSVTACKTLIQAGRQMPRSQALPIERELFVGLFDTEDQA
EGVNAFLEKRKADWKNR

Specific function: Could Possibly Oxidizes Fatty Acids Using Specific Components (By Similarity). [C]

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=261, Percent_Identity=34.8659003831418, Blast_Score=143, Evalue=2e-34,
Organism=Homo sapiens, GI68989263, Length=207, Percent_Identity=35.2657004830918, Blast_Score=111, Evalue=7e-25,
Organism=Homo sapiens, GI157694516, Length=228, Percent_Identity=28.9473684210526, Blast_Score=89, Evalue=3e-18,
Organism=Homo sapiens, GI213417737, Length=228, Percent_Identity=28.9473684210526, Blast_Score=89, Evalue=3e-18,
Organism=Homo sapiens, GI4502327, Length=237, Percent_Identity=30.379746835443, Blast_Score=88, Evalue=9e-18,
Organism=Homo sapiens, GI20127408, Length=179, Percent_Identity=32.9608938547486, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI31542718, Length=260, Percent_Identity=27.6923076923077, Blast_Score=85, Evalue=7e-17,
Organism=Homo sapiens, GI157694520, Length=210, Percent_Identity=29.0476190476191, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI261878539, Length=109, Percent_Identity=43.1192660550459, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI150378541, Length=256, Percent_Identity=30.46875, Blast_Score=74, Evalue=9e-14,
Organism=Homo sapiens, GI37594471, Length=155, Percent_Identity=26.4516129032258, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI37594469, Length=155, Percent_Identity=26.4516129032258, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI70995211, Length=226, Percent_Identity=28.3185840707965, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI62530384, Length=186, Percent_Identity=27.9569892473118, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI221136756, Length=259, Percent_Identity=24.7104247104247, Blast_Score=65, Evalue=6e-11,
Organism=Homo sapiens, GI221136753, Length=259, Percent_Identity=24.7104247104247, Blast_Score=65, Evalue=6e-11,
Organism=Homo sapiens, GI221307494, Length=259, Percent_Identity=24.7104247104247, Blast_Score=65, Evalue=7e-11,
Organism=Escherichia coli, GI1787659, Length=259, Percent_Identity=38.6100386100386, Blast_Score=152, Evalue=3e-38,
Organism=Escherichia coli, GI221142681, Length=247, Percent_Identity=33.1983805668016, Blast_Score=132, Evalue=1e-32,
Organism=Escherichia coli, GI1788682, Length=196, Percent_Identity=36.2244897959184, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI1790281, Length=207, Percent_Identity=29.4685990338164, Blast_Score=77, Evalue=8e-16,
Organism=Escherichia coli, GI87082183, Length=202, Percent_Identity=25.2475247524752, Blast_Score=77, Evalue=9e-16,
Organism=Escherichia coli, GI1788597, Length=252, Percent_Identity=25, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1787660, Length=262, Percent_Identity=27.8625954198473, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI25145438, Length=254, Percent_Identity=35.0393700787402, Blast_Score=136, Evalue=9e-33,
Organism=Caenorhabditis elegans, GI17554946, Length=248, Percent_Identity=33.0645161290323, Blast_Score=136, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI17540714, Length=233, Percent_Identity=32.618025751073, Blast_Score=116, Evalue=9e-27,
Organism=Caenorhabditis elegans, GI17558304, Length=187, Percent_Identity=31.5508021390374, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI25144160, Length=192, Percent_Identity=29.1666666666667, Blast_Score=81, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI25144157, Length=192, Percent_Identity=29.1666666666667, Blast_Score=81, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17536985, Length=258, Percent_Identity=25.1937984496124, Blast_Score=80, Evalue=9e-16,
Organism=Caenorhabditis elegans, GI25144276, Length=194, Percent_Identity=31.4432989690722, Blast_Score=78, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17508953, Length=194, Percent_Identity=31.4432989690722, Blast_Score=77, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17508951, Length=194, Percent_Identity=31.4432989690722, Blast_Score=77, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI17534483, Length=189, Percent_Identity=26.984126984127, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17560910, Length=260, Percent_Identity=27.3076923076923, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17540306, Length=259, Percent_Identity=25.0965250965251, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI20129971, Length=264, Percent_Identity=34.469696969697, Blast_Score=135, Evalue=2e-32,
Organism=Drosophila melanogaster, GI24653477, Length=264, Percent_Identity=34.469696969697, Blast_Score=135, Evalue=2e-32,
Organism=Drosophila melanogaster, GI24653139, Length=262, Percent_Identity=32.824427480916, Blast_Score=121, Evalue=4e-28,
Organism=Drosophila melanogaster, GI24650670, Length=196, Percent_Identity=32.1428571428571, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24583165, Length=245, Percent_Identity=25.7142857142857, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI21357171, Length=149, Percent_Identity=32.8859060402685, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI19922422, Length=244, Percent_Identity=22.9508196721311, Blast_Score=71, Evalue=9e-13,
Organism=Drosophila melanogaster, GI19921018, Length=190, Percent_Identity=27.3684210526316, Blast_Score=69, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.55 [H]

Molecular weight: Translated: 27382; Mature: 27382

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: PS00166 ENOYL_COA_HYDRATASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEYLVERIEGHTAILTMNNPPANTWTAQSLQALKAKVLELNANKDIYALVLTGEGNKFFS
CHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHHEECCCCCEEEEEEECCCCEEEE
AGADLKLFSDGDKGNAASMAKHFGEAFETLSQFRGVSIAAINGYAMGGGLEVALACDIRI
CCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEECCEEECCCEEEEEEEEEEE
AETQAVMALPEATVGLLPCAGGTQNLTALVGEGWAKRMILCGERVNAAQALNLRLVEEVV
ECCHHHEECCCCCEEEEECCCCCCCHHHHHCCCHHHHHHHCCCCCCHHHHHHHHHHHHHH
ETGEALNAAIALAAKVANQSPSSVTACKTLIQAGRQMPRSQALPIERELFVGLFDTEDQA
HCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHEEEEECCCCHH
EGVNAFLEKRKADWKNR
HHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MEYLVERIEGHTAILTMNNPPANTWTAQSLQALKAKVLELNANKDIYALVLTGEGNKFFS
CHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHHEECCCCCEEEEEEECCCCEEEE
AGADLKLFSDGDKGNAASMAKHFGEAFETLSQFRGVSIAAINGYAMGGGLEVALACDIRI
CCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEECCEEECCCEEEEEEEEEEE
AETQAVMALPEATVGLLPCAGGTQNLTALVGEGWAKRMILCGERVNAAQALNLRLVEEVV
ECCHHHEECCCCCEEEEECCCCCCCHHHHHCCCHHHHHHHCCCCCCHHHHHHHHHHHHHH
ETGEALNAAIALAAKVANQSPSSVTACKTLIQAGRQMPRSQALPIERELFVGLFDTEDQA
HCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHEEEEECCCCHH
EGVNAFLEKRKADWKNR
HHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8655474; 11466286 [H]