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The map label for this gene is rrmA [H]

Identifier: 117921011

GI number: 117921011

Start: 3074223

End: 3075038

Strand: Reverse

Name: rrmA [H]

Synonym: Shewana3_2570

Alternate gene names: 117921011

Gene position: 3075038-3074223 (Counterclockwise)

Preceding gene: 117921012

Following gene: 117921010

Centisome position: 61.84

GC content: 47.18

Gene sequence:

>816_bases
ATGCAATATATATGTCCTTTGTGTGCCTTACCGCTCACCTTGACTGAACGAACTTGGGGATGCCCGCAGGCACACAAGTT
CGACATGGCCAAAGAAGGTTATGTGAATCTGCTTCCCGTGCAGAAGAAAAATTCCAAAGATCCCGGTGACAATCAACAGA
TGATGTTGGCTCGCAGGGAGTTTTTAACTGCGGGTTACTATCAAAGTTTGAGTGACAGAGTGAATGAACTTGCACTTGCG
TATGCCAGCGAGGCCCGGCAGATCCTCGATATCGGCTGTGGTGAGGGGTATTACAGCCATCGTTTGTACAATACGCTTGT
CGCCGAGCATCCTTGCCAGTTAAAGGGCGTGGACATCTCCAAATCTGCGATAAAATATGCGGCTAAACGTTACCCGAACC
TCAGCTTTTGTGTGGCGAGCGCCTACGAAATGCCCATTCCATCGCATAGTATCGATTTAGCGATTCGTATTTATGCGCCA
TCGAAGGTGGAAGAGTTACAGCGGGTCATGGCGCCCAATGGCATTTTGATCACTGTATCGCCAGGACCTTTACATCATTT
TGCGCTAAAACAGCAAATTTATGCCGAACCGAGATTGCATCCAGCGTCCGATGCCAAGATTGCGGGGTTCGAATGCTTAT
ACCAAGAGCGCCTTAGGTCACAACTTGAGCTAAATAATAGCCAAGATATTAGCCATTTTCTGGAAATGACTCCCTACGCT
TGGAAGTTTACAGCCGAACAAAAGCACACATTTGCACAGAGCGGATTAAGCTGCGAATTAGACTTTCAGATTGAAGTACA
TCGCATTTCAGTCTAG

Upstream 100 bases:

>100_bases
TTTTGAGCTGCTCGCCTCCCCTGAATTACTGCAAATGGTGGAGCGACTCATGGAAGATGAGGCATAAGCCAGCCATTCCA
ATCATTTATAGAGTTAACCA

Downstream 100 bases:

>100_bases
AGGTTGATTTTAAGCTATTGAAATAAATTATTTAAAATGCTTAACTGTCGATGCTTACGCCGTAAGAACATGCTGTTCTG
CGAGCCGGTGGCAAAACCTG

Product: 23S rRNA methyltransferase A

Products: NA

Alternate protein names: 23S rRNA m1G745 methyltransferase; rRNA (guanine-N(1)-)-methyltransferase [H]

Number of amino acids: Translated: 271; Mature: 271

Protein sequence:

>271_residues
MQYICPLCALPLTLTERTWGCPQAHKFDMAKEGYVNLLPVQKKNSKDPGDNQQMMLARREFLTAGYYQSLSDRVNELALA
YASEARQILDIGCGEGYYSHRLYNTLVAEHPCQLKGVDISKSAIKYAAKRYPNLSFCVASAYEMPIPSHSIDLAIRIYAP
SKVEELQRVMAPNGILITVSPGPLHHFALKQQIYAEPRLHPASDAKIAGFECLYQERLRSQLELNNSQDISHFLEMTPYA
WKFTAEQKHTFAQSGLSCELDFQIEVHRISV

Sequences:

>Translated_271_residues
MQYICPLCALPLTLTERTWGCPQAHKFDMAKEGYVNLLPVQKKNSKDPGDNQQMMLARREFLTAGYYQSLSDRVNELALA
YASEARQILDIGCGEGYYSHRLYNTLVAEHPCQLKGVDISKSAIKYAAKRYPNLSFCVASAYEMPIPSHSIDLAIRIYAP
SKVEELQRVMAPNGILITVSPGPLHHFALKQQIYAEPRLHPASDAKIAGFECLYQERLRSQLELNNSQDISHFLEMTPYA
WKFTAEQKHTFAQSGLSCELDFQIEVHRISV
>Mature_271_residues
MQYICPLCALPLTLTERTWGCPQAHKFDMAKEGYVNLLPVQKKNSKDPGDNQQMMLARREFLTAGYYQSLSDRVNELALA
YASEARQILDIGCGEGYYSHRLYNTLVAEHPCQLKGVDISKSAIKYAAKRYPNLSFCVASAYEMPIPSHSIDLAIRIYAP
SKVEELQRVMAPNGILITVSPGPLHHFALKQQIYAEPRLHPASDAKIAGFECLYQERLRSQLELNNSQDISHFLEMTPYA
WKFTAEQKHTFAQSGLSCELDFQIEVHRISV

Specific function: Specifically methylates the guanosine in position 745 of 23S rRNA [H]

COG id: COG0500

COG function: function code QR; SAM-dependent methyltransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RlmA family [H]

Homologues:

Organism=Escherichia coli, GI1788125, Length=268, Percent_Identity=46.6417910447761, Blast_Score=236, Evalue=9e-64,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013216
- InterPro:   IPR016718 [H]

Pfam domain/function: PF08241 Methyltransf_11 [H]

EC number: =2.1.1.187 [H]

Molecular weight: Translated: 30704; Mature: 30704

Theoretical pI: Translated: 7.26; Mature: 7.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQYICPLCALPLTLTERTWGCPQAHKFDMAKEGYVNLLPVQKKNSKDPGDNQQMMLARRE
CCCCCCHHHCCCEECCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHH
FLTAGYYQSLSDRVNELALAYASEARQILDIGCGEGYYSHRLYNTLVAEHPCQLKGVDIS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCEECCCCC
KSAIKYAAKRYPNLSFCVASAYEMPIPSHSIDLAIRIYAPSKVEELQRVMAPNGILITVS
HHHHHHHHHHCCCCEEEEHHHHCCCCCCCCEEEEEEEECCHHHHHHHHHHCCCCEEEEEC
PGPLHHFALKQQIYAEPRLHPASDAKIAGFECLYQERLRSQLELNNSQDISHFLEMTPYA
CCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCE
WKFTAEQKHTFAQSGLSCELDFQIEVHRISV
EEEECHHHHHHHHCCCCEEEEEEEEEEEECC
>Mature Secondary Structure
MQYICPLCALPLTLTERTWGCPQAHKFDMAKEGYVNLLPVQKKNSKDPGDNQQMMLARRE
CCCCCCHHHCCCEECCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHH
FLTAGYYQSLSDRVNELALAYASEARQILDIGCGEGYYSHRLYNTLVAEHPCQLKGVDIS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCEECCCCC
KSAIKYAAKRYPNLSFCVASAYEMPIPSHSIDLAIRIYAPSKVEELQRVMAPNGILITVS
HHHHHHHHHHCCCCEEEEHHHHCCCCCCCCEEEEEEEECCHHHHHHHHHHCCCCEEEEEC
PGPLHHFALKQQIYAEPRLHPASDAKIAGFECLYQERLRSQLELNNSQDISHFLEMTPYA
CCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCE
WKFTAEQKHTFAQSGLSCELDFQIEVHRISV
EEEECHHHHHHHHCCCCEEEEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7984109; 9097040; 9278503; 9440525 [H]