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The map label for this gene is queC

Identifier: 117920608

GI number: 117920608

Start: 2592986

End: 2593705

Strand: Direct

Name: queC

Synonym: Shewana3_2164

Alternate gene names: 117920608

Gene position: 2592986-2593705 (Clockwise)

Preceding gene: 117920603

Following gene: 117920609

Centisome position: 52.15

GC content: 50.56

Gene sequence:

>720_bases
ATGTCAGCAGCGTCAGTTTCAAAGGTGGTAGTGGTTTTCAGTGGCGGACAAGACTCAACGACTTGTCTTATTCAAGCCTT
AACTCAGTTTGATGAAGTCCACGGGATCACCTTTGATTATGGTCAGCGTCACCGTGAAGAAATTGAAGTTGCCAAATCCC
TCGCCAAGCGCTTAAAGATCACTAGCCATAAAGTGATAGATGTGAGCTTACTCAATGAGTTAGCTATTTCTGCCCTCACC
CGCGATGCGATCCCCGTGTCCCACGAATTAATGGAAAATGGCTTACCCAATACCTTTGTGCCGGGCCGCAATATCCTGTT
TTTGACTTTGGCGGGGATCTACGCCTACCAACTAGGGGCAGGGGCGATTATTACCGGCGTGTGTGAAACCGATTTTTCCG
GTTATCCCGACTGTCGCCACGACTTTGTGCGCGCGATGGAATCGGCACTGGTGCAAGGCATGGACAAAAAGCTTGAGATC
ATCACGCCATTAATGTGGCTCAATAAGGCTCAAACCTGGGCGCTGGCCGATAAATACCAGCAGCTCGATTTAGTTCGCCA
CCATACCCTAACCTGTTATAACGGCATTGTCGGCGATGGTTGCGGTGCTTGCCCAGCCTGCCATCTTCGCAAACGGGGCT
TAGAGGATTACCTGCAAAATAAAGCAGAGGTGATGGCCTCGCTGGACAAGGCAACTGCAACGGGTAAACCACAGGCGTGA

Upstream 100 bases:

>100_bases
GAGCGATATGCCCGTCGCCACACGCCAGCAAAGAGTTTGCAAGCCCTAGCGCCTGAGTTACACTTACGCCCTATTTTATG
TGTCAATTTAAGTGGATCCT

Downstream 100 bases:

>100_bases
GACTGGTAACGTTAAAAAAACTCGGCCCCTATTGGCTGGCGCTTATCGTCAGTCTGCTCTGCGCACTCTTGTATGTTGCG
GGACTTTTTACCCCGAGCAT

Product: queuosine biosynthesis protein QueC

Products: NA

Alternate protein names: 7-cyano-7-carbaguanine synthase; PreQ(0) synthase; Queuosine biosynthesis protein queC

Number of amino acids: Translated: 239; Mature: 238

Protein sequence:

>239_residues
MSAASVSKVVVVFSGGQDSTTCLIQALTQFDEVHGITFDYGQRHREEIEVAKSLAKRLKITSHKVIDVSLLNELAISALT
RDAIPVSHELMENGLPNTFVPGRNILFLTLAGIYAYQLGAGAIITGVCETDFSGYPDCRHDFVRAMESALVQGMDKKLEI
ITPLMWLNKAQTWALADKYQQLDLVRHHTLTCYNGIVGDGCGACPACHLRKRGLEDYLQNKAEVMASLDKATATGKPQA

Sequences:

>Translated_239_residues
MSAASVSKVVVVFSGGQDSTTCLIQALTQFDEVHGITFDYGQRHREEIEVAKSLAKRLKITSHKVIDVSLLNELAISALT
RDAIPVSHELMENGLPNTFVPGRNILFLTLAGIYAYQLGAGAIITGVCETDFSGYPDCRHDFVRAMESALVQGMDKKLEI
ITPLMWLNKAQTWALADKYQQLDLVRHHTLTCYNGIVGDGCGACPACHLRKRGLEDYLQNKAEVMASLDKATATGKPQA
>Mature_238_residues
SAASVSKVVVVFSGGQDSTTCLIQALTQFDEVHGITFDYGQRHREEIEVAKSLAKRLKITSHKVIDVSLLNELAISALTR
DAIPVSHELMENGLPNTFVPGRNILFLTLAGIYAYQLGAGAIITGVCETDFSGYPDCRHDFVRAMESALVQGMDKKLEII
TPLMWLNKAQTWALADKYQQLDLVRHHTLTCYNGIVGDGCGACPACHLRKRGLEDYLQNKAEVMASLDKATATGKPQA

Specific function: Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))

COG id: COG0603

COG function: function code R; Predicted PP-loop superfamily ATPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the queC family

Homologues:

Organism=Escherichia coli, GI1786648, Length=228, Percent_Identity=65.7894736842105, Blast_Score=321, Evalue=2e-89,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): QUEC_SHESA (A0KX75)

Other databases:

- EMBL:   CP000469
- RefSeq:   YP_869800.1
- ProteinModelPortal:   A0KX75
- SMR:   A0KX75
- STRING:   A0KX75
- GeneID:   4478363
- GenomeReviews:   CP000469_GR
- KEGG:   shn:Shewana3_2164
- NMPDR:   fig|94122.5.peg.2229
- eggNOG:   COG0603
- HOGENOM:   HBG553284
- OMA:   CETDYSG
- PhylomeDB:   A0KX75
- ProtClustDB:   PRK11106
- BioCyc:   SSP94122:SHEWANA3_2164-MONOMER
- HAMAP:   MF_01633_B
- InterPro:   IPR018317
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PIRSF:   PIRSF006293
- TIGRFAMs:   TIGR00364

Pfam domain/function: PF06508 ExsB

EC number: NA

Molecular weight: Translated: 26140; Mature: 26009

Theoretical pI: Translated: 6.71; Mature: 6.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAASVSKVVVVFSGGQDSTTCLIQALTQFDEVHGITFDYGQRHREEIEVAKSLAKRLKI
CCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
TSHKVIDVSLLNELAISALTRDAIPVSHELMENGLPNTFVPGRNILFLTLAGIYAYQLGA
HCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCC
GAIITGVCETDFSGYPDCRHDFVRAMESALVQGMDKKLEIITPLMWLNKAQTWALADKYQ
CCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHH
QLDLVRHHTLTCYNGIVGDGCGACPACHLRKRGLEDYLQNKAEVMASLDKATATGKPQA
HHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SAASVSKVVVVFSGGQDSTTCLIQALTQFDEVHGITFDYGQRHREEIEVAKSLAKRLKI
CCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
TSHKVIDVSLLNELAISALTRDAIPVSHELMENGLPNTFVPGRNILFLTLAGIYAYQLGA
HCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCC
GAIITGVCETDFSGYPDCRHDFVRAMESALVQGMDKKLEIITPLMWLNKAQTWALADKYQ
CCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHH
QLDLVRHHTLTCYNGIVGDGCGACPACHLRKRGLEDYLQNKAEVMASLDKATATGKPQA
HHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA