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The map label for this gene is efp [H]

Identifier: 117920585

GI number: 117920585

Start: 2565576

End: 2566136

Strand: Direct

Name: efp [H]

Synonym: Shewana3_2141

Alternate gene names: 117920585

Gene position: 2565576-2566136 (Clockwise)

Preceding gene: 117920584

Following gene: 117920589

Centisome position: 51.6

GC content: 43.67

Gene sequence:

>561_bases
ATGAAAACTGCTCATGAAGTCCGTCCTGGTAACGTGATCATGTTTGAAGGCAGCCCATGGGTTGTACAGAAAACAGAAAC
AACTCGTTCTGGCCGTAACGCTGCCATCGTTAAGTTAAAGCTGAAAAACTTACTGCTTAACTCTGGTACTGAAACCACTT
TCAAAGGTGAAGATAAGATTGACGATATTATCCTAGATCGTCTGGATTGTACTTATTCTTACTTTGCTGATCCTATGTAC
GTGTTCATGGATGCAGAATACAACCAATACGACGTAGAAGCTGAGAACTTAGGTGATGCTGCGGCTTACATCGTTGACGG
TATGGAAGAAACTTGCCAAGTAACTTTCTACGAAGGCAAAGCAATTTCTGTTGAAATGCCAACCACTATCGTACGTGAAG
TGATCTACACTGAGCCATCAGCTCGTGGCGATACTTCAGGTAAAGTAATGAAGCCAGCAACTATCACTGGCGGCGGTACA
ATCAGCGTGGCTGACTTCGTTAAAGTTGGCGACAAGATTGAAATCGACACTCGTACTGGCGAATTCAAGAAGCGCGTATA
A

Upstream 100 bases:

>100_bases
CAATAAATGCTGCAGATCTTGCGACTCGGCTAGTCCAATTCGTCAAAAAAAGCTAAGATGCTGCGCTGAAATAGAAAATC
GACATATAGGAAATTGTGTA

Downstream 100 bases:

>100_bases
TCGCCCTTCCTACTTGTCTCGTCCTGAAATAAGTTGACACTTATTTCCACCTAAAACGCTCGATGAACCTCATCGGGCGT
TTTGTATTTTAAGGCCAAAT

Product: elongation factor P

Products: NA

Alternate protein names: EF-P [H]

Number of amino acids: Translated: 186; Mature: 186

Protein sequence:

>186_residues
MKTAHEVRPGNVIMFEGSPWVVQKTETTRSGRNAAIVKLKLKNLLLNSGTETTFKGEDKIDDIILDRLDCTYSYFADPMY
VFMDAEYNQYDVEAENLGDAAAYIVDGMEETCQVTFYEGKAISVEMPTTIVREVIYTEPSARGDTSGKVMKPATITGGGT
ISVADFVKVGDKIEIDTRTGEFKKRV

Sequences:

>Translated_186_residues
MKTAHEVRPGNVIMFEGSPWVVQKTETTRSGRNAAIVKLKLKNLLLNSGTETTFKGEDKIDDIILDRLDCTYSYFADPMY
VFMDAEYNQYDVEAENLGDAAAYIVDGMEETCQVTFYEGKAISVEMPTTIVREVIYTEPSARGDTSGKVMKPATITGGGT
ISVADFVKVGDKIEIDTRTGEFKKRV
>Mature_186_residues
MKTAHEVRPGNVIMFEGSPWVVQKTETTRSGRNAAIVKLKLKNLLLNSGTETTFKGEDKIDDIILDRLDCTYSYFADPMY
VFMDAEYNQYDVEAENLGDAAAYIVDGMEETCQVTFYEGKAISVEMPTTIVREVIYTEPSARGDTSGKVMKPATITGGGT
ISVADFVKVGDKIEIDTRTGEFKKRV

Specific function: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing t

COG id: COG0231

COG function: function code J; Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the elongation factor P family [H]

Homologues:

Organism=Escherichia coli, GI1790590, Length=184, Percent_Identity=34.7826086956522, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI87082061, Length=178, Percent_Identity=28.6516853932584, Blast_Score=85, Evalue=2e-18,

Paralogues:

None

Copy number: 1600 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015365
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR020599
- InterPro:   IPR013185
- InterPro:   IPR001059
- InterPro:   IPR011768
- InterPro:   IPR014722
- InterPro:   IPR008991 [H]

Pfam domain/function: PF01132 EFP; PF08207 EFP_N; PF09285 Elong-fact-P_C [H]

EC number: NA

Molecular weight: Translated: 20634; Mature: 20634

Theoretical pI: Translated: 4.54; Mature: 4.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTAHEVRPGNVIMFEGSPWVVQKTETTRSGRNAAIVKLKLKNLLLNSGTETTFKGEDKI
CCCCCCCCCCCEEEECCCCEEEEECCCCCCCCCEEEEEEEEEEHHCCCCCCCEECCCCCH
DDIILDRLDCTYSYFADPMYVFMDAEYNQYDVEAENLGDAAAYIVDGMEETCQVTFYEGK
HHHHHHHHCCCHHHHCCEEEEEEECCCCEEECCHHHCCCEEEEECCCCCCCEEEEEECCE
AISVEMPTTIVREVIYTEPSARGDTSGKVMKPATITGGGTISVADFVKVGDKIEIDTRTG
EEEEECCHHHHHHHHHCCCCCCCCCCCCEECCEEECCCCEEEHHHHHHCCCEEEEECCCC
EFKKRV
CHHCCC
>Mature Secondary Structure
MKTAHEVRPGNVIMFEGSPWVVQKTETTRSGRNAAIVKLKLKNLLLNSGTETTFKGEDKI
CCCCCCCCCCCEEEECCCCEEEEECCCCCCCCCEEEEEEEEEEHHCCCCCCCEECCCCCH
DDIILDRLDCTYSYFADPMYVFMDAEYNQYDVEAENLGDAAAYIVDGMEETCQVTFYEGK
HHHHHHHHCCCHHHHCCEEEEEEECCCCEEECCHHHCCCEEEEECCCCCCCEEEEEECCE
AISVEMPTTIVREVIYTEPSARGDTSGKVMKPATITGGGTISVADFVKVGDKIEIDTRTG
EEEEECCHHHHHHHHHCCCCCCCCCCCCEECCEEECCCCEEEHHHHHHCCCEEEEECCCC
EFKKRV
CHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA