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The map label for this gene is yfbQ [H]

Identifier: 117920589

GI number: 117920589

Start: 2569796

End: 2571010

Strand: Direct

Name: yfbQ [H]

Synonym: Shewana3_2145

Alternate gene names: 117920589

Gene position: 2569796-2571010 (Clockwise)

Preceding gene: 117920585

Following gene: 117920590

Centisome position: 51.68

GC content: 49.38

Gene sequence:

>1215_bases
ATGCGCCCTATCATCAAGTCCAACAAGTTGGATACTGTTTGCTACGACATCCGCGGCCCAGTGCACAAGGAAGCCAGACG
TTTAGAAGACGAGGGACACCGCATCCTCAAACTCAACATTGGTAACCCCGCCCCCTTCGGTTTTGAAGCGCCGGAAGAAA
TTGTGCGCGATGTGATCCTCAATCTTCCCAGCGCCCAAGGCTACTGTGAGTCGAAAGGATTATTCTCTGCCCGCAAGGCG
ATTGTGCAGCATTATCAAGCGCAGGGCATTAAAGGCGTCGATATCGAAGATGTCTATATCGGTAATGGTGTGTCAGAGCT
GATTATGATGGCCATGCAGGGCTTATTAAACACCGATGATGAAGTGCTGCTCCCCTCTCCCGACTATCCGCTATGGACCG
CGGCGGCGAATTTAGCCGGCGGTAAAGCGGTACATTACCGCTGCGATGAAGAGGCGGATTGGTTCCCGGATCTTGATGAT
ATTAAGAGCAAAATTTCGTCTCGTACCCGTGGTATTGTGCTGATTAACCCGAACAACCCAACGGGCGCTGTTTACAGTAA
AGAATTACTGCTGCAAGTTATCGAGCTCTGCCGCGAGCACAACCTGATCCTGTTTGCCGATGAAATCTACGATAAGATTT
TATACGACGAGGCCAAACATATTCCGGCCGCGAGCCTCTCTGACGATATCTTAACCGTGACCTTTAATGGTCTTTCAAAA
GCCTATCGCGCAGCGGGCTTTCGTGTCGGTTGGATGATGTTGTCTGGCAATCTTAAGGCTGCCAAGAGTTATATCGAAGG
TTTAGAGATGCTTTCCTCGATGCGCCTGTGTGCCAACGTGCCGAATCAACATGCGATTCAAACCGCGCTCGGCGGTTACC
AAAGCATTAATGAGCTGATTTTACCTAGCGGCCGCTTAACCGTGCAGCGCGATACCTGTTATGAGTTATTGAACCAAATT
CCCGGTGTGAGCGTGAAAAAGCCCAAGGGGGCACTGTACGCCTTCCCCAAACTGGACATGAAAAAGTTCAACCTCAGGGA
TGATGAGCGCTTAGTACTCGATTTGCTCAGGGATAAAAAAATCCTCCTCGTACACGGCAGCGCCTTTAACTGGCCAGAGC
CGGATCATTTAAGAGTGGTGTTTTTACCCTATAAGGAAGATTTGACTAAAGCATTGACAGAGTTTGGCAATTTCCTCGAG
ACCTACAAACAATAA

Upstream 100 bases:

>100_bases
AAAACTTGTTATTTGTGCTCAAGCCCCCTTCCTTAAGCCATATAATTTCGTTATGGTGCACAAACTTAAGCCTAAATTAA
CTGCATGTTTCGAGGTGTAA

Downstream 100 bases:

>100_bases
TGTTTTAGTCTCACCGCCAAGATGACCATTAGGTTAACCTCGACTAAAGCGATCCTCTGGGTCGCTTTATTTTTGCTGTG
CGTAAAAACTCTTCAATCAT

Product: aminotransferase AlaT

Products: oxaloacetate; L-glutamate

Alternate protein names: NA

Number of amino acids: Translated: 404; Mature: 404

Protein sequence:

>404_residues
MRPIIKSNKLDTVCYDIRGPVHKEARRLEDEGHRILKLNIGNPAPFGFEAPEEIVRDVILNLPSAQGYCESKGLFSARKA
IVQHYQAQGIKGVDIEDVYIGNGVSELIMMAMQGLLNTDDEVLLPSPDYPLWTAAANLAGGKAVHYRCDEEADWFPDLDD
IKSKISSRTRGIVLINPNNPTGAVYSKELLLQVIELCREHNLILFADEIYDKILYDEAKHIPAASLSDDILTVTFNGLSK
AYRAAGFRVGWMMLSGNLKAAKSYIEGLEMLSSMRLCANVPNQHAIQTALGGYQSINELILPSGRLTVQRDTCYELLNQI
PGVSVKKPKGALYAFPKLDMKKFNLRDDERLVLDLLRDKKILLVHGSAFNWPEPDHLRVVFLPYKEDLTKALTEFGNFLE
TYKQ

Sequences:

>Translated_404_residues
MRPIIKSNKLDTVCYDIRGPVHKEARRLEDEGHRILKLNIGNPAPFGFEAPEEIVRDVILNLPSAQGYCESKGLFSARKA
IVQHYQAQGIKGVDIEDVYIGNGVSELIMMAMQGLLNTDDEVLLPSPDYPLWTAAANLAGGKAVHYRCDEEADWFPDLDD
IKSKISSRTRGIVLINPNNPTGAVYSKELLLQVIELCREHNLILFADEIYDKILYDEAKHIPAASLSDDILTVTFNGLSK
AYRAAGFRVGWMMLSGNLKAAKSYIEGLEMLSSMRLCANVPNQHAIQTALGGYQSINELILPSGRLTVQRDTCYELLNQI
PGVSVKKPKGALYAFPKLDMKKFNLRDDERLVLDLLRDKKILLVHGSAFNWPEPDHLRVVFLPYKEDLTKALTEFGNFLE
TYKQ
>Mature_404_residues
MRPIIKSNKLDTVCYDIRGPVHKEARRLEDEGHRILKLNIGNPAPFGFEAPEEIVRDVILNLPSAQGYCESKGLFSARKA
IVQHYQAQGIKGVDIEDVYIGNGVSELIMMAMQGLLNTDDEVLLPSPDYPLWTAAANLAGGKAVHYRCDEEADWFPDLDD
IKSKISSRTRGIVLINPNNPTGAVYSKELLLQVIELCREHNLILFADEIYDKILYDEAKHIPAASLSDDILTVTFNGLSK
AYRAAGFRVGWMMLSGNLKAAKSYIEGLEMLSSMRLCANVPNQHAIQTALGGYQSINELILPSGRLTVQRDTCYELLNQI
PGVSVKKPKGALYAFPKLDMKKFNLRDDERLVLDLLRDKKILLVHGSAFNWPEPDHLRVVFLPYKEDLTKALTEFGNFLE
TYKQ

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI4507369, Length=376, Percent_Identity=26.5957446808511, Blast_Score=137, Evalue=1e-32,
Organism=Homo sapiens, GI4885351, Length=450, Percent_Identity=25.3333333333333, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI19263340, Length=477, Percent_Identity=25.9958071278826, Blast_Score=119, Evalue=5e-27,
Organism=Homo sapiens, GI215599424, Length=386, Percent_Identity=26.6839378238342, Blast_Score=115, Evalue=9e-26,
Organism=Homo sapiens, GI95147551, Length=266, Percent_Identity=27.4436090225564, Blast_Score=96, Evalue=5e-20,
Organism=Homo sapiens, GI169881279, Length=266, Percent_Identity=27.4436090225564, Blast_Score=96, Evalue=5e-20,
Organism=Homo sapiens, GI56713256, Length=338, Percent_Identity=25.4437869822485, Blast_Score=92, Evalue=6e-19,
Organism=Homo sapiens, GI56713254, Length=338, Percent_Identity=25.4437869822485, Blast_Score=92, Evalue=8e-19,
Organism=Homo sapiens, GI169881281, Length=147, Percent_Identity=31.2925170068027, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI149944424, Length=388, Percent_Identity=22.680412371134, Blast_Score=79, Evalue=8e-15,
Organism=Escherichia coli, GI1788627, Length=404, Percent_Identity=69.059405940594, Blast_Score=609, Evalue=1e-175,
Organism=Escherichia coli, GI1788722, Length=396, Percent_Identity=25, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1786816, Length=298, Percent_Identity=23.489932885906, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1787909, Length=297, Percent_Identity=21.5488215488215, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17567663, Length=370, Percent_Identity=27.2972972972973, Blast_Score=152, Evalue=3e-37,
Organism=Caenorhabditis elegans, GI71981209, Length=463, Percent_Identity=25.2699784017279, Blast_Score=110, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI71994476, Length=204, Percent_Identity=27.9411764705882, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI71994472, Length=204, Percent_Identity=27.9411764705882, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI71981215, Length=293, Percent_Identity=25.938566552901, Blast_Score=83, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17567369, Length=172, Percent_Identity=29.0697674418605, Blast_Score=82, Evalue=6e-16,
Organism=Saccharomyces cerevisiae, GI6320317, Length=380, Percent_Identity=25.7894736842105, Blast_Score=120, Evalue=3e-28,
Organism=Saccharomyces cerevisiae, GI6323118, Length=384, Percent_Identity=26.0416666666667, Blast_Score=118, Evalue=2e-27,
Organism=Saccharomyces cerevisiae, GI6322401, Length=237, Percent_Identity=25.7383966244726, Blast_Score=108, Evalue=1e-24,
Organism=Drosophila melanogaster, GI18859735, Length=378, Percent_Identity=24.8677248677249, Blast_Score=149, Evalue=2e-36,
Organism=Drosophila melanogaster, GI45551451, Length=478, Percent_Identity=24.0585774058577, Blast_Score=109, Evalue=4e-24,
Organism=Drosophila melanogaster, GI24641770, Length=478, Percent_Identity=24.0585774058577, Blast_Score=108, Evalue=5e-24,
Organism=Drosophila melanogaster, GI24641760, Length=478, Percent_Identity=24.0585774058577, Blast_Score=108, Evalue=5e-24,
Organism=Drosophila melanogaster, GI24641768, Length=478, Percent_Identity=24.0585774058577, Blast_Score=108, Evalue=5e-24,
Organism=Drosophila melanogaster, GI24641766, Length=478, Percent_Identity=24.0585774058577, Blast_Score=108, Evalue=5e-24,
Organism=Drosophila melanogaster, GI24641764, Length=478, Percent_Identity=24.0585774058577, Blast_Score=108, Evalue=5e-24,
Organism=Drosophila melanogaster, GI28573069, Length=327, Percent_Identity=25.0764525993884, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24646114, Length=327, Percent_Identity=25.0764525993884, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI28573067, Length=327, Percent_Identity=25.0764525993884, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI28573065, Length=327, Percent_Identity=25.0764525993884, Blast_Score=91, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.1

Molecular weight: Translated: 45336; Mature: 45336

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPIIKSNKLDTVCYDIRGPVHKEARRLEDEGHRILKLNIGNPAPFGFEAPEEIVRDVIL
CCCCCCCCCCCEEEEECCCCHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHH
NLPSAQGYCESKGLFSARKAIVQHYQAQGIKGVDIEDVYIGNGVSELIMMAMQGLLNTDD
CCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEECCCHHHHHHHHHHHHCCCCC
EVLLPSPDYPLWTAAANLAGGKAVHYRCDEEADWFPDLDDIKSKISSRTRGIVLINPNNP
CEEECCCCCCHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHCEEEEECCCCC
TGAVYSKELLLQVIELCREHNLILFADEIYDKILYDEAKHIPAASLSDDILTVTFNGLSK
CCHHHHHHHHHHHHHHHHHCCEEEEHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEHHHHH
AYRAAGFRVGWMMLSGNLKAAKSYIEGLEMLSSMRLCANVPNQHAIQTALGGYQSINELI
HHHHCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHH
LPSGRLTVQRDTCYELLNQIPGVSVKKPKGALYAFPKLDMKKFNLRDDERLVLDLLRDKK
CCCCCEEEEHHHHHHHHHHCCCCEEECCCCCEEECCCCCCHHCCCCCHHHHHHHHHCCCE
ILLVHGSAFNWPEPDHLRVVFLPYKEDLTKALTEFGNFLETYKQ
EEEEECCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRPIIKSNKLDTVCYDIRGPVHKEARRLEDEGHRILKLNIGNPAPFGFEAPEEIVRDVIL
CCCCCCCCCCCEEEEECCCCHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHH
NLPSAQGYCESKGLFSARKAIVQHYQAQGIKGVDIEDVYIGNGVSELIMMAMQGLLNTDD
CCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEECCCHHHHHHHHHHHHCCCCC
EVLLPSPDYPLWTAAANLAGGKAVHYRCDEEADWFPDLDDIKSKISSRTRGIVLINPNNP
CEEECCCCCCHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHCEEEEECCCCC
TGAVYSKELLLQVIELCREHNLILFADEIYDKILYDEAKHIPAASLSDDILTVTFNGLSK
CCHHHHHHHHHHHHHHHHHCCEEEEHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEHHHHH
AYRAAGFRVGWMMLSGNLKAAKSYIEGLEMLSSMRLCANVPNQHAIQTALGGYQSINELI
HHHHCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHH
LPSGRLTVQRDTCYELLNQIPGVSVKKPKGALYAFPKLDMKKFNLRDDERLVLDLLRDKK
CCCCCEEEEHHHHHHHHHHCCCCEEECCCCCEEECCCCCCHHCCCCCHHHHHHHHHCCCE
ILLVHGSAFNWPEPDHLRVVFLPYKEDLTKALTEFGNFLETYKQ
EEEEECCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-aspartate; 2-oxoglutarate

Specific reaction: L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]