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The map label for this gene is aspC [H]

Identifier: 117920419

GI number: 117920419

Start: 2352012

End: 2353202

Strand: Reverse

Name: aspC [H]

Synonym: Shewana3_1974

Alternate gene names: 117920419

Gene position: 2353202-2352012 (Counterclockwise)

Preceding gene: 117920430

Following gene: 117920416

Centisome position: 47.33

GC content: 48.95

Gene sequence:

>1191_bases
ATGTTTAACTCACTCGTCGCAATGCCTGCGGATCCTATCCTCGGCCTATTAACCCAGTACCGTGAAGACTCACATCCTCA
AAAAGTCGACTTAGGTGTGGGCGTATATAAGGATCCCGCTGGAAACACTCCCATCCTTAATTGCGTGAAAAAAGCCGAAA
AATTCCGTTTAGACACTGAAACCACCAAAGTGTATATCGGCCCAACCGGTTCACCTCAGTTTAATACCCTGATAACAGAA
TTAGCCTTTGGCAGTGATCACAGCGCGATTATCACCAACCGCATTCGTACTGTTTCTACTCCTGGTGGCACGGGCGCCCT
GCGCGTTGCCGGTGATTTTATTAAACGCTGCAATCCTAATGCTGTGCTATGGGTGAGCGATCCCACATGGGCTAACCATA
TAGGCTTGTTTGAAGCGGCGGGTCTGACCGTTAAAACCTACCCTTACTATGATTACGACACTAAATCGTTAAAGTTCGAT
GAGATGCTCAGCGCGCTTGCGCAGATTGGCCCGAACGATGTGGTGCTATTCCACGCCTGTTGCCATAACCCAAGCGGGAT
GGATTTAACGACAGAACAATGGGATAAAGTGGTTGCCCTCACCAAGGAGCAAGGTTTTACCCCGCTTATCGACATGGCTT
ACCAAGGTTTTGGTGATGGGGTCGATATCGATGCCTACGGCGTGCGTAAAATGGCCGCTGCGGTCGATAATATGATCCTG
TGTAGCTCTTGCTCGAAAAACTTCGGTCTGTACCGTGAGCGTATCGGTTCATGCTCTGTGGTTGCAAAAGATGCAAACAC
GGCAAACATCGCGCAATCTGTGCTGCTTTACGTGGTTCGCTGCCTCTACTCCATGCCGCCAGCCCACGGCGCGGCGATTG
TCGAAACCATTCTAGGTTCGGCAGAATTAAAGCAAGAATGGTTAGATGAGCTGAAAGTGATGCGCGACCGTATCAACGGT
AACCGCGCCATTTTAGTGGAAAAACTCAAAACCAATGGCGTGGACCGCGACTTTAGCTTTATCGCACGCCAAAAAGGCAT
GTTCTCTTTCCTAGGGGTTAATCCTGAGCAAGTCGCGCGTCTGCAGAAAGAATTCAGCATTTATATGGTGGGTTCGAGTC
GCATTAGCATTGCAGGCATTAGCGAAGACAATGTGGATTACTTAGCTAAGTCGATTGCAAAAGTACTGTAA

Upstream 100 bases:

>100_bases
TTTTTCATCTATCCACGCTATTCTAGGTTTCAAACGATAAATCACGCATATTCTTTGCAATTCATGTTGTCGCAATATAA
CCAAAAAGGTAGATGGAGCC

Downstream 100 bases:

>100_bases
CAAGACTGTTGGGATGAAGCGCCTAATTCGGCCTAAGTCCCCTAGCCTTCCTTTAGCTATTACTTAGTGCATGCTTTCAT
ATTAACTTTAAGCTTTATGC

Product: aromatic amino acid aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 396; Mature: 396

Protein sequence:

>396_residues
MFNSLVAMPADPILGLLTQYREDSHPQKVDLGVGVYKDPAGNTPILNCVKKAEKFRLDTETTKVYIGPTGSPQFNTLITE
LAFGSDHSAIITNRIRTVSTPGGTGALRVAGDFIKRCNPNAVLWVSDPTWANHIGLFEAAGLTVKTYPYYDYDTKSLKFD
EMLSALAQIGPNDVVLFHACCHNPSGMDLTTEQWDKVVALTKEQGFTPLIDMAYQGFGDGVDIDAYGVRKMAAAVDNMIL
CSSCSKNFGLYRERIGSCSVVAKDANTANIAQSVLLYVVRCLYSMPPAHGAAIVETILGSAELKQEWLDELKVMRDRING
NRAILVEKLKTNGVDRDFSFIARQKGMFSFLGVNPEQVARLQKEFSIYMVGSSRISIAGISEDNVDYLAKSIAKVL

Sequences:

>Translated_396_residues
MFNSLVAMPADPILGLLTQYREDSHPQKVDLGVGVYKDPAGNTPILNCVKKAEKFRLDTETTKVYIGPTGSPQFNTLITE
LAFGSDHSAIITNRIRTVSTPGGTGALRVAGDFIKRCNPNAVLWVSDPTWANHIGLFEAAGLTVKTYPYYDYDTKSLKFD
EMLSALAQIGPNDVVLFHACCHNPSGMDLTTEQWDKVVALTKEQGFTPLIDMAYQGFGDGVDIDAYGVRKMAAAVDNMIL
CSSCSKNFGLYRERIGSCSVVAKDANTANIAQSVLLYVVRCLYSMPPAHGAAIVETILGSAELKQEWLDELKVMRDRING
NRAILVEKLKTNGVDRDFSFIARQKGMFSFLGVNPEQVARLQKEFSIYMVGSSRISIAGISEDNVDYLAKSIAKVL
>Mature_396_residues
MFNSLVAMPADPILGLLTQYREDSHPQKVDLGVGVYKDPAGNTPILNCVKKAEKFRLDTETTKVYIGPTGSPQFNTLITE
LAFGSDHSAIITNRIRTVSTPGGTGALRVAGDFIKRCNPNAVLWVSDPTWANHIGLFEAAGLTVKTYPYYDYDTKSLKFD
EMLSALAQIGPNDVVLFHACCHNPSGMDLTTEQWDKVVALTKEQGFTPLIDMAYQGFGDGVDIDAYGVRKMAAAVDNMIL
CSSCSKNFGLYRERIGSCSVVAKDANTANIAQSVLLYVVRCLYSMPPAHGAAIVETILGSAELKQEWLDELKVMRDRING
NRAILVEKLKTNGVDRDFSFIARQKGMFSFLGVNPEQVARLQKEFSIYMVGSSRISIAGISEDNVDYLAKSIAKVL

Specific function: Unknown

COG id: COG1448

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI73486658, Length=390, Percent_Identity=41.5384615384615, Blast_Score=307, Evalue=1e-83,
Organism=Homo sapiens, GI4504067, Length=400, Percent_Identity=38.5, Blast_Score=271, Evalue=1e-72,
Organism=Homo sapiens, GI117414139, Length=381, Percent_Identity=26.509186351706, Blast_Score=134, Evalue=2e-31,
Organism=Escherichia coli, GI1787159, Length=396, Percent_Identity=48.989898989899, Blast_Score=410, Evalue=1e-116,
Organism=Escherichia coli, GI1790488, Length=398, Percent_Identity=40.9547738693467, Blast_Score=332, Evalue=3e-92,
Organism=Caenorhabditis elegans, GI71981858, Length=395, Percent_Identity=40.7594936708861, Blast_Score=328, Evalue=3e-90,
Organism=Caenorhabditis elegans, GI25147133, Length=390, Percent_Identity=42.0512820512821, Blast_Score=317, Evalue=8e-87,
Organism=Caenorhabditis elegans, GI17569539, Length=396, Percent_Identity=34.5959595959596, Blast_Score=242, Evalue=3e-64,
Organism=Caenorhabditis elegans, GI17569537, Length=388, Percent_Identity=29.3814432989691, Blast_Score=165, Evalue=3e-41,
Organism=Caenorhabditis elegans, GI25147136, Length=206, Percent_Identity=38.8349514563107, Blast_Score=159, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI17550384, Length=263, Percent_Identity=28.1368821292776, Blast_Score=140, Evalue=1e-33,
Organism=Saccharomyces cerevisiae, GI6323055, Length=405, Percent_Identity=36.7901234567901, Blast_Score=287, Evalue=2e-78,
Organism=Saccharomyces cerevisiae, GI6322743, Length=425, Percent_Identity=32.4705882352941, Blast_Score=226, Evalue=4e-60,
Organism=Drosophila melanogaster, GI24580972, Length=396, Percent_Identity=39.6464646464646, Blast_Score=300, Evalue=9e-82,
Organism=Drosophila melanogaster, GI24580970, Length=396, Percent_Identity=39.6464646464646, Blast_Score=300, Evalue=9e-82,
Organism=Drosophila melanogaster, GI19920542, Length=389, Percent_Identity=40.1028277634961, Blast_Score=299, Evalue=2e-81,
Organism=Drosophila melanogaster, GI24654046, Length=387, Percent_Identity=40.0516795865633, Blast_Score=288, Evalue=6e-78,
Organism=Drosophila melanogaster, GI19922362, Length=387, Percent_Identity=40.0516795865633, Blast_Score=287, Evalue=7e-78,

Paralogues:

None

Copy number: 6,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000796
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 43391; Mature: 43391

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFNSLVAMPADPILGLLTQYREDSHPQKVDLGVGVYKDPAGNTPILNCVKKAEKFRLDTE
CCCCEECCCCCHHHHHHHHHHCCCCCCEEEECCCEEECCCCCCHHHHHHHHHHHHCCCCC
TTKVYIGPTGSPQFNTLITELAFGSDHSAIITNRIRTVSTPGGTGALRVAGDFIKRCNPN
CEEEEECCCCCCHHHHHHHHHHCCCCCCCEEECCEEEEECCCCCCEEHHHHHHHHHCCCC
AVLWVSDPTWANHIGLFEAAGLTVKTYPYYDYDTKSLKFDEMLSALAQIGPNDVVLFHAC
EEEEECCCCCCHHCCCEECCCCEEEECCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEEEE
CHNPSGMDLTTEQWDKVVALTKEQGFTPLIDMAYQGFGDGVDIDAYGVRKMAAAVDNMIL
CCCCCCCCCCHHHHHHEEEEECCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCE
CSSCSKNFGLYRERIGSCSVVAKDANTANIAQSVLLYVVRCLYSMPPAHGAAIVETILGS
ECCCCCCCCHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCC
AELKQEWLDELKVMRDRINGNRAILVEKLKTNGVDRDFSFIARQKGMFSFLGVNPEQVAR
HHHHHHHHHHHHHHHHHHCCCEEEEEEEHHCCCCCCHHHHHHHHCCCEEEECCCHHHHHH
LQKEFSIYMVGSSRISIAGISEDNVDYLAKSIAKVL
HHHHCEEEEEECCEEEEEECCCCCHHHHHHHHHHHC
>Mature Secondary Structure
MFNSLVAMPADPILGLLTQYREDSHPQKVDLGVGVYKDPAGNTPILNCVKKAEKFRLDTE
CCCCEECCCCCHHHHHHHHHHCCCCCCEEEECCCEEECCCCCCHHHHHHHHHHHHCCCCC
TTKVYIGPTGSPQFNTLITELAFGSDHSAIITNRIRTVSTPGGTGALRVAGDFIKRCNPN
CEEEEECCCCCCHHHHHHHHHHCCCCCCCEEECCEEEEECCCCCCEEHHHHHHHHHCCCC
AVLWVSDPTWANHIGLFEAAGLTVKTYPYYDYDTKSLKFDEMLSALAQIGPNDVVLFHAC
EEEEECCCCCCHHCCCEECCCCEEEECCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEEEE
CHNPSGMDLTTEQWDKVVALTKEQGFTPLIDMAYQGFGDGVDIDAYGVRKMAAAVDNMIL
CCCCCCCCCCHHHHHHEEEEECCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCE
CSSCSKNFGLYRERIGSCSVVAKDANTANIAQSVLLYVVRCLYSMPPAHGAAIVETILGS
ECCCCCCCCHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCC
AELKQEWLDELKVMRDRINGNRAILVEKLKTNGVDRDFSFIARQKGMFSFLGVNPEQVAR
HHHHHHHHHHHHHHHHHHCCCEEEEEEEHHCCCCCCHHHHHHHHCCCEEEECCCHHHHHH
LQKEFSIYMVGSSRISIAGISEDNVDYLAKSIAKVL
HHHHCEEEEEECCEEEEEECCCCCHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]