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The map label for this gene is ubiG

Identifier: 117920416

GI number: 117920416

Start: 2346739

End: 2347449

Strand: Reverse

Name: ubiG

Synonym: Shewana3_1971

Alternate gene names: 117920416

Gene position: 2347449-2346739 (Counterclockwise)

Preceding gene: 117920419

Following gene: 117920415

Centisome position: 47.21

GC content: 48.52

Gene sequence:

>711_bases
ATGCAACAGAATACCAACGTAGACCCGCTGGAAATCGCAAAGTTTGAACGTATGGCCGAAACCTGGTGGGATCTCAACGG
CGAGTTTAAGCCGCTGCATCTATTAAATCCCCTGCGCCTTAACTATATCGATCAAACGGCAGGCGGGATTTTTGGTAAGA
AAGTGCTGGACGTCGGCTGCGGCGGCGGCATTTTATCCGAAAGCATGGCGCGCATCGGCGCGATCGTTCACGGCCTCGAT
ATGGGTGAAGAACCATTAGAAGTCGCGCGTTTACATGCACTGGAAACTGGCGTGAGCATCAACTATGTCAAAAACACTGC
CGAGGCCCATCGGGAAGAACACCGCGAATACTATGATGTGGTGACCTGTATGGAGATGCTCGAGCATGTACCAGATCCAC
AATCAGTCATTCAAGCCTGCTGCGATATGGTTAAACCCGGCGGTTTTGTGTTTTTCTCAACCATCAACCGTAACATTAAG
TCTTTCGTCGAGACCATTATCGGCGCCGAGTACCTATTAAAGATGCTGCCCATTGGCACCCATGACCATAATAAGTTCAT
CAAGCCATCGGAACTCATGGCCTTAGTCGATAACACCGATCTTCTCTGTAAAGATGCACTTGGGATCACCTATAACCCAC
TGACGGGGATCTTTAAGTACACGCCAAAGGTCGATGTTAATTATATGATTGCGACGCAAAAGGTAGATTAA

Upstream 100 bases:

>100_bases
AATTTCACTCAACCACAAAGACTTAGGATCAGCCAATACTGTGTTTATCCCCCATTGTCGTTATAATAGCCGCACAATGA
CAGCCGTAATAGGTAATAGC

Downstream 100 bases:

>100_bases
GATGAGTTTAGCTGAGGTTAAAGGGGTCTTATTCGACCTTGACGGTACCCTTGCCGATACCGCGCCGGATCTGGTTCAGG
CCCTTAACCTCAGTTTGTCG

Product: 3-demethylubiquinone-9 3-methyltransferase

Products: NA

Alternate protein names: 3,4-dihydroxy-5-hexaprenylbenzoate methyltransferase; DHHB methyltransferase

Number of amino acids: Translated: 236; Mature: 236

Protein sequence:

>236_residues
MQQNTNVDPLEIAKFERMAETWWDLNGEFKPLHLLNPLRLNYIDQTAGGIFGKKVLDVGCGGGILSESMARIGAIVHGLD
MGEEPLEVARLHALETGVSINYVKNTAEAHREEHREYYDVVTCMEMLEHVPDPQSVIQACCDMVKPGGFVFFSTINRNIK
SFVETIIGAEYLLKMLPIGTHDHNKFIKPSELMALVDNTDLLCKDALGITYNPLTGIFKYTPKVDVNYMIATQKVD

Sequences:

>Translated_236_residues
MQQNTNVDPLEIAKFERMAETWWDLNGEFKPLHLLNPLRLNYIDQTAGGIFGKKVLDVGCGGGILSESMARIGAIVHGLD
MGEEPLEVARLHALETGVSINYVKNTAEAHREEHREYYDVVTCMEMLEHVPDPQSVIQACCDMVKPGGFVFFSTINRNIK
SFVETIIGAEYLLKMLPIGTHDHNKFIKPSELMALVDNTDLLCKDALGITYNPLTGIFKYTPKVDVNYMIATQKVD
>Mature_236_residues
MQQNTNVDPLEIAKFERMAETWWDLNGEFKPLHLLNPLRLNYIDQTAGGIFGKKVLDVGCGGGILSESMARIGAIVHGLD
MGEEPLEVARLHALETGVSINYVKNTAEAHREEHREYYDVVTCMEMLEHVPDPQSVIQACCDMVKPGGFVFFSTINRNIK
SFVETIIGAEYLLKMLPIGTHDHNKFIKPSELMALVDNTDLLCKDALGITYNPLTGIFKYTPKVDVNYMIATQKVD

Specific function: Ubiquinone biosynthesis. [C]

COG id: COG2227

COG function: function code H; 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. UbiG/COQ3 family

Homologues:

Organism=Homo sapiens, GI118600965, Length=239, Percent_Identity=34.7280334728033, Blast_Score=160, Evalue=1e-39,
Organism=Escherichia coli, GI1788564, Length=230, Percent_Identity=65.6521739130435, Blast_Score=323, Evalue=8e-90,
Organism=Caenorhabditis elegans, GI115533050, Length=244, Percent_Identity=29.0983606557377, Blast_Score=111, Evalue=4e-25,
Organism=Saccharomyces cerevisiae, GI6324476, Length=282, Percent_Identity=30.1418439716312, Blast_Score=128, Evalue=9e-31,
Organism=Drosophila melanogaster, GI281365311, Length=244, Percent_Identity=32.3770491803279, Blast_Score=142, Evalue=1e-34,
Organism=Drosophila melanogaster, GI24585589, Length=210, Percent_Identity=34.2857142857143, Blast_Score=139, Evalue=2e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UBIG_SHESA (A0KWN3)

Other databases:

- EMBL:   CP000469
- RefSeq:   YP_869608.1
- ProteinModelPortal:   A0KWN3
- SMR:   A0KWN3
- STRING:   A0KWN3
- GeneID:   4476335
- GenomeReviews:   CP000469_GR
- KEGG:   shn:Shewana3_1971
- NMPDR:   fig|94122.5.peg.2045
- eggNOG:   COG2227
- HOGENOM:   HBG738842
- OMA:   DHAEIAK
- PhylomeDB:   A0KWN3
- ProtClustDB:   PRK05134
- BioCyc:   SSP94122:SHEWANA3_1971-MONOMER
- HAMAP:   MF_00472
- InterPro:   IPR013216
- InterPro:   IPR010233
- TIGRFAMs:   TIGR01983

Pfam domain/function: PF08241 Methyltransf_11

EC number: =2.1.1.64

Molecular weight: Translated: 26447; Mature: 26447

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQQNTNVDPLEIAKFERMAETWWDLNGEFKPLHLLNPLRLNYIDQTAGGIFGKKVLDVGC
CCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEECCCCHHHCHHHHHHCCHHHHHHHHCCC
GGGILSESMARIGAIVHGLDMGEEPLEVARLHALETGVSINYVKNTAEAHREEHREYYDV
CCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHH
VTCMEMLEHVPDPQSVIQACCDMVKPGGFVFFSTINRNIKSFVETIIGAEYLLKMLPIGT
HHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCC
HDHNKFIKPSELMALVDNTDLLCKDALGITYNPLTGIFKYTPKVDVNYMIATQKVD
CCCCCCCCHHHHHHHHCCCCHHHHHCCCCEECCCHHHEEECCCCCCEEEEEEECCC
>Mature Secondary Structure
MQQNTNVDPLEIAKFERMAETWWDLNGEFKPLHLLNPLRLNYIDQTAGGIFGKKVLDVGC
CCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEECCCCHHHCHHHHHHCCHHHHHHHHCCC
GGGILSESMARIGAIVHGLDMGEEPLEVARLHALETGVSINYVKNTAEAHREEHREYYDV
CCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHH
VTCMEMLEHVPDPQSVIQACCDMVKPGGFVFFSTINRNIKSFVETIIGAEYLLKMLPIGT
HHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCC
HDHNKFIKPSELMALVDNTDLLCKDALGITYNPLTGIFKYTPKVDVNYMIATQKVD
CCCCCCCCHHHHHHHHCCCCHHHHHCCCCEECCCHHHEEECCCCCCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA