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The map label for this gene is scoA [H]

Identifier: 117920114

GI number: 117920114

Start: 1958315

End: 1959019

Strand: Reverse

Name: scoA [H]

Synonym: Shewana3_1667

Alternate gene names: 117920114

Gene position: 1959019-1958315 (Counterclockwise)

Preceding gene: 117920115

Following gene: 117920113

Centisome position: 39.4

GC content: 50.92

Gene sequence:

>705_bases
ATGGCAGGACTCAATAAAGTCGTCAGCAGCTATGAAGAAGCGTTAACAGGTTTATCCGATGATATGACCATTATGGTTGG
CGGTTTTGGCCTGTGCGGTATTCCTGAAGGCTTAATCAATCAAATGGTTAAGATGGGCATTAAGGGCTTAACCGCCATTT
CGAATAATGCCGGTGTGGATGATTTCGGTCTGGGCTTATTGTTAAAACACCGCCAGATTTCGACCATGATCGCCTCCTAC
GTGGGTGAGAACGCCACCTTCGAGCAGCAAATGCTCTCGGGCGAACTGAATGTGATTTTAACGCCACAGGGCACGCTGGC
GGAAAAAATCCGCGCCGGCGGTGCAGGTATTCCGGCATTTTTCACCGCCACAGGCTACGGCACCCCCGTGGCGGAGGGTA
AAGAAACCCGTGAAATCAAAGGCCGTCACTATGTGTTAGAAGAATCTCTGACCGCCGATTTTGCCCTCGTTCGCGCTTGG
AAGGCCGATACTATGGGTAACTTAGTGTTTCGCAAAACCGCCGCGAACTTTAACCCTATGATGGCGACTGCGGGTAAAAT
CACGGTAGTGGAAGCCGAGTTTATTGTTGAGCCGGGCGAGCTCGATCCTGGTCATATCCATACTCCCGGCATTTATGTTG
ATCGCGTCATCCAAGGCAAGTTCGAGAAACGTATCGAGCAGCGCACGGTAAAAGCGGCGAAATAA

Upstream 100 bases:

>100_bases
CCAATGCAATCTTGCAGGGCGCCAAAGCCTAGACTCAAGCGTCGAGGCGCTCAACATACCTAGCGCCTTGGGGACTGAAT
AACAGTAAAAGGACATCAAA

Downstream 100 bases:

>100_bases
GAAACGCGAACGATTAACAACGCAAGCTAAAGCGACAGAGTCTAAGCCCTAAATAAAGACCGAAAAATTGAGGCCAATAG
CGACTCTAGGTAAAGGAAGG

Product: 3-oxoacid CoA-transferase subunit A

Products: NA

Alternate protein names: Succinyl CoA:3-oxoacid CoA-transferase; OXCT A [H]

Number of amino acids: Translated: 234; Mature: 233

Protein sequence:

>234_residues
MAGLNKVVSSYEEALTGLSDDMTIMVGGFGLCGIPEGLINQMVKMGIKGLTAISNNAGVDDFGLGLLLKHRQISTMIASY
VGENATFEQQMLSGELNVILTPQGTLAEKIRAGGAGIPAFFTATGYGTPVAEGKETREIKGRHYVLEESLTADFALVRAW
KADTMGNLVFRKTAANFNPMMATAGKITVVEAEFIVEPGELDPGHIHTPGIYVDRVIQGKFEKRIEQRTVKAAK

Sequences:

>Translated_234_residues
MAGLNKVVSSYEEALTGLSDDMTIMVGGFGLCGIPEGLINQMVKMGIKGLTAISNNAGVDDFGLGLLLKHRQISTMIASY
VGENATFEQQMLSGELNVILTPQGTLAEKIRAGGAGIPAFFTATGYGTPVAEGKETREIKGRHYVLEESLTADFALVRAW
KADTMGNLVFRKTAANFNPMMATAGKITVVEAEFIVEPGELDPGHIHTPGIYVDRVIQGKFEKRIEQRTVKAAK
>Mature_233_residues
AGLNKVVSSYEEALTGLSDDMTIMVGGFGLCGIPEGLINQMVKMGIKGLTAISNNAGVDDFGLGLLLKHRQISTMIASYV
GENATFEQQMLSGELNVILTPQGTLAEKIRAGGAGIPAFFTATGYGTPVAEGKETREIKGRHYVLEESLTADFALVRAWK
ADTMGNLVFRKTAANFNPMMATAGKITVVEAEFIVEPGELDPGHIHTPGIYVDRVIQGKFEKRIEQRTVKAAK

Specific function: SHORT-CHAIN FATTY ACIDS METABOLISM. [C]

COG id: COG1788

COG function: function code I; Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-oxoacid CoA-transferase subunit A family [H]

Homologues:

Organism=Homo sapiens, GI4557817, Length=238, Percent_Identity=58.4033613445378, Blast_Score=282, Evalue=2e-76,
Organism=Homo sapiens, GI11545841, Length=237, Percent_Identity=54.0084388185654, Blast_Score=244, Evalue=3e-65,
Organism=Escherichia coli, GI1788551, Length=214, Percent_Identity=44.8598130841121, Blast_Score=193, Evalue=9e-51,
Organism=Caenorhabditis elegans, GI17531517, Length=243, Percent_Identity=53.9094650205761, Blast_Score=264, Evalue=3e-71,
Organism=Drosophila melanogaster, GI21358325, Length=248, Percent_Identity=51.2096774193548, Blast_Score=247, Evalue=5e-66,
Organism=Drosophila melanogaster, GI24655794, Length=248, Percent_Identity=51.2096774193548, Blast_Score=246, Evalue=7e-66,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012792
- InterPro:   IPR004165
- InterPro:   IPR004163 [H]

Pfam domain/function: PF01144 CoA_trans [H]

EC number: =2.8.3.5 [H]

Molecular weight: Translated: 25109; Mature: 24978

Theoretical pI: Translated: 6.13; Mature: 6.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGLNKVVSSYEEALTGLSDDMTIMVGGFGLCGIPEGLINQMVKMGIKGLTAISNNAGVD
CCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHHHHHHHHCHHHHEEECCCCCCC
DFGLGLLLKHRQISTMIASYVGENATFEQQMLSGELNVILTPQGTLAEKIRAGGAGIPAF
CHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCEEEECCCCHHHHHHHCCCCCCCCE
FTATGYGTPVAEGKETREIKGRHYVLEESLTADFALVRAWKADTMGNLVFRKTAANFNPM
EEECCCCCCCCCCCCHHHHCCCEEEEHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCC
MATAGKITVVEAEFIVEPGELDPGHIHTPGIYVDRVIQGKFEKRIEQRTVKAAK
EECCCEEEEEEEEEEEECCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AGLNKVVSSYEEALTGLSDDMTIMVGGFGLCGIPEGLINQMVKMGIKGLTAISNNAGVD
CCHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHHHHHHHHCHHHHEEECCCCCCC
DFGLGLLLKHRQISTMIASYVGENATFEQQMLSGELNVILTPQGTLAEKIRAGGAGIPAF
CHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCEEEECCCCHHHHHHHCCCCCCCCE
FTATGYGTPVAEGKETREIKGRHYVLEESLTADFALVRAWKADTMGNLVFRKTAANFNPM
EEECCCCCCCCCCCCHHHHCCCEEEEHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCC
MATAGKITVVEAEFIVEPGELDPGHIHTPGIYVDRVIQGKFEKRIEQRTVKAAK
EECCCEEEEEEEEEEEECCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969509; 9384377 [H]