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The map label for this gene is fabH2 [H]

Identifier: 117920029

GI number: 117920029

Start: 1850125

End: 1851189

Strand: Reverse

Name: fabH2 [H]

Synonym: Shewana3_1581

Alternate gene names: 117920029

Gene position: 1851189-1850125 (Counterclockwise)

Preceding gene: 117920030

Following gene: 117920026

Centisome position: 37.23

GC content: 48.64

Gene sequence:

>1065_bases
ATGCAGTACGCCACTATCACTGGCTGGGGAAAATGTGTTCCTCCCGCCACTTTGACTAACGATGATCTTGCTACTTTTAT
CGAAACTTCCGATGAATGGATTAAAAGCCGTACCGGGATCAGCCAGCGTCATATCAGCCATGTGAATACCTCTGAGTTAG
CATCGGTTGCCGCTAAACGCGCCCTTGCTGCGGCGGGCATTGACGGCAGCGAAATTGATATGATCATTTTAGCCAGCGCC
AGCCCAGATACCTTGATCCCGAATATTGCCTCCACAGTACAGGCGAATATTGGTGCAAGTTGCGCAGCTTTCGATATCAA
CGCGGCCTGCAGTGGCTTTTTGTATGGCTTAGGCTTAGCCAGCTCACAGATCAAGAGTGGCCAATGCAAAAAAGTACTAG
TAGTCGGTGCAGAGCGTTTATCTTTCTACCTCGATTGGTCACGCCGTGAAACCGCAGTACTGTTTGGTGATGGCGCGGGC
GCGGTTGTTGTGGAAGCGACCGATGTGCCAGGCGGTGTGTTAGGCTATGAGCTGAATAACGACCCTGACGGTCGCGATAT
CCTAAAAGCCGGTTTTGGTACTGCGATGGATAGATTCTCCGCCGAATCCTTAGATTTTTATATTCAATTCGATGGCCAAG
AAATCTTTAAACGTGCCATCAATGGTATGAATAAGTTAAGCACTCAAGTGCTGGAAAAATGTGGCGTCGATAAGGATGAA
GTCGACTTAGTGATCCCACACCAAGCGAACGAGCGCATTATCGATACCCTCGTTAGCCGCATGAAGATCCCTAAAGAAAA
AGCCTTCGTGAACATTGCTAACTATGGTAATACCTCTGCGGCCACTATTCCCATTGCCATCTGCGATGCATTGGAGAAAG
GTTTAATTAAGCCAAATCAAACTATTTTGTCATGTGCCTTCGGTGCGGGGTTAACCTCAGCAGCGCTGCTATTGCAATGG
GGCGAACGCGTAACACCAGTTCAAGTGAGCGATGCCCAGCTGCCACCTTGCGAGTTGAGTGGCATTGAGCTGGTTAAACG
TGCAGTGGATTATTTCTGTAAGTAA

Upstream 100 bases:

>100_bases
TGGTCTAGATCACGGACTGTCATTCGTTATACCGATAAGCTTTGTTGTCGATTTGAGGCAGCACTTCAGGTTCTGCCTTT
TTTATTTGAGAGAAAACACC

Downstream 100 bases:

>100_bases
TAAATCCCGAACACAGATAAAAGGCCATCTTGGGATGGCCTTTTACATTTTTATCTCTTCAGGCACTCGACGCATTTCAT
CCCAGTAAATCCCCTGCTTA

Product: 3-oxoacyl-(acyl carrier protein) synthase III

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase III protein 2; Beta-ketoacyl-ACP synthase III 2; KAS III 2 [H]

Number of amino acids: Translated: 354; Mature: 354

Protein sequence:

>354_residues
MQYATITGWGKCVPPATLTNDDLATFIETSDEWIKSRTGISQRHISHVNTSELASVAAKRALAAAGIDGSEIDMIILASA
SPDTLIPNIASTVQANIGASCAAFDINAACSGFLYGLGLASSQIKSGQCKKVLVVGAERLSFYLDWSRRETAVLFGDGAG
AVVVEATDVPGGVLGYELNNDPDGRDILKAGFGTAMDRFSAESLDFYIQFDGQEIFKRAINGMNKLSTQVLEKCGVDKDE
VDLVIPHQANERIIDTLVSRMKIPKEKAFVNIANYGNTSAATIPIAICDALEKGLIKPNQTILSCAFGAGLTSAALLLQW
GERVTPVQVSDAQLPPCELSGIELVKRAVDYFCK

Sequences:

>Translated_354_residues
MQYATITGWGKCVPPATLTNDDLATFIETSDEWIKSRTGISQRHISHVNTSELASVAAKRALAAAGIDGSEIDMIILASA
SPDTLIPNIASTVQANIGASCAAFDINAACSGFLYGLGLASSQIKSGQCKKVLVVGAERLSFYLDWSRRETAVLFGDGAG
AVVVEATDVPGGVLGYELNNDPDGRDILKAGFGTAMDRFSAESLDFYIQFDGQEIFKRAINGMNKLSTQVLEKCGVDKDE
VDLVIPHQANERIIDTLVSRMKIPKEKAFVNIANYGNTSAATIPIAICDALEKGLIKPNQTILSCAFGAGLTSAALLLQW
GERVTPVQVSDAQLPPCELSGIELVKRAVDYFCK
>Mature_354_residues
MQYATITGWGKCVPPATLTNDDLATFIETSDEWIKSRTGISQRHISHVNTSELASVAAKRALAAAGIDGSEIDMIILASA
SPDTLIPNIASTVQANIGASCAAFDINAACSGFLYGLGLASSQIKSGQCKKVLVVGAERLSFYLDWSRRETAVLFGDGAG
AVVVEATDVPGGVLGYELNNDPDGRDILKAGFGTAMDRFSAESLDFYIQFDGQEIFKRAINGMNKLSTQVLEKCGVDKDE
VDLVIPHQANERIIDTLVSRMKIPKEKAFVNIANYGNTSAATIPIAICDALEKGLIKPNQTILSCAFGAGLTSAALLLQW
GERVTPVQVSDAQLPPCELSGIELVKRAVDYFCK

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the

COG id: COG0332

COG function: function code I; 3-oxoacyl-[acyl-carrier-protein] synthase III

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabH family [H]

Homologues:

Organism=Escherichia coli, GI1787333, Length=321, Percent_Identity=36.7601246105919, Blast_Score=209, Evalue=2e-55,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013751
- InterPro:   IPR013747
- InterPro:   IPR004655
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF08545 ACP_syn_III; PF08541 ACP_syn_III_C [H]

EC number: =2.3.1.180 [H]

Molecular weight: Translated: 37743; Mature: 37743

Theoretical pI: Translated: 4.68; Mature: 4.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQYATITGWGKCVPPATLTNDDLATFIETSDEWIKSRTGISQRHISHVNTSELASVAAKR
CCEEEECCCCCCCCCCCCCCCHHHHHHHCCHHHHHHHCCCCHHHHHCCCHHHHHHHHHHH
ALAAAGIDGSEIDMIILASASPDTLIPNIASTVQANIGASCAAFDINAACSGFLYGLGLA
HHHHCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHCCCCCEEEEECHHHHHHHHHHHCCC
SSQIKSGQCKKVLVVGAERLSFYLDWSRRETAVLFGDGAGAVVVEATDVPGGVLGYELNN
HHHCCCCCCCEEEEEEHHHEEEEEECCCCCEEEEEECCCCEEEEEECCCCCCEEEEECCC
DPDGRDILKAGFGTAMDRFSAESLDFYIQFDGQEIFKRAINGMNKLSTQVLEKCGVDKDE
CCCHHHHHHHHHHHHHHHCCCCCEEEEEEECCHHHHHHHHCCHHHHHHHHHHHHCCCCCC
VDLVIPHQANERIIDTLVSRMKIPKEKAFVNIANYGNTSAATIPIAICDALEKGLIKPNQ
EEEECCCCCCHHHHHHHHHHHCCCCHHHEEEEECCCCCCCCEEHHHHHHHHHHCCCCCCH
TILSCAFGAGLTSAALLLQWGERVTPVQVSDAQLPPCELSGIELVKRAVDYFCK
HHEEEHHCCCHHHHHHHHHHCCCCCCEEECCCCCCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MQYATITGWGKCVPPATLTNDDLATFIETSDEWIKSRTGISQRHISHVNTSELASVAAKR
CCEEEECCCCCCCCCCCCCCCHHHHHHHCCHHHHHHHCCCCHHHHHCCCHHHHHHHHHHH
ALAAAGIDGSEIDMIILASASPDTLIPNIASTVQANIGASCAAFDINAACSGFLYGLGLA
HHHHCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHCCCCCEEEEECHHHHHHHHHHHCCC
SSQIKSGQCKKVLVVGAERLSFYLDWSRRETAVLFGDGAGAVVVEATDVPGGVLGYELNN
HHHCCCCCCCEEEEEEHHHEEEEEECCCCCEEEEEECCCCEEEEEECCCCCCEEEEECCC
DPDGRDILKAGFGTAMDRFSAESLDFYIQFDGQEIFKRAINGMNKLSTQVLEKCGVDKDE
CCCHHHHHHHHHHHHHHHCCCCCEEEEEEECCHHHHHHHHCCHHHHHHHHHHHHCCCCCC
VDLVIPHQANERIIDTLVSRMKIPKEKAFVNIANYGNTSAATIPIAICDALEKGLIKPNQ
EEEECCCCCCHHHHHHHHHHHCCCCHHHEEEEECCCCCCCCEEHHHHHHHHHHCCCCCCH
TILSCAFGAGLTSAALLLQWGERVTPVQVSDAQLPPCELSGIELVKRAVDYFCK
HHEEEHHCCCHHHHHHHHHHCCCCCCEEECCCCCCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]