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The map label for this gene is ribH [H]

Identifier: 117919548

GI number: 117919548

Start: 1293461

End: 1294003

Strand: Direct

Name: ribH [H]

Synonym: Shewana3_1099

Alternate gene names: 117919548

Gene position: 1293461-1294003 (Clockwise)

Preceding gene: 117919547

Following gene: 117919549

Centisome position: 26.01

GC content: 46.04

Gene sequence:

>543_bases
TTGACTGTGGTATCATGTCGCCACTTTTCGCCCAAGCCGGGTGCTTTAGCTAAATTAGGTAAGAAAATGAACGTAGTTCA
AGGTAATATCGAAGCGAAGAATGCCAAAGTTGCGATTGTAATTTCGCGTTTTAACAGCTTTTTAGTTGAGAGCTTGCTTG
AAAGTGCACTTGACACGCTGAAACGTTTTGGCCAAGTCAGTGATGAAAACATCACTGTCGTCCGTGTACCTGGTGCGGTT
GAGTTACCGCTGGCTGCACGTCGTGTTGCCGCAAGTGGTAAGTTTGACGGTATCATCGCACTTGGTGCTGTGATCCGTGG
TGGTACCCCTCATTTTGATTTTGTTGCAGGTGAATGTAACAAAGGTCTAGCTCAAATCGCATTAGAGTTCGATCTGCCCG
TTGCCTTCGGTGTATTGACGACAGATACCATTGAACAAGCCATTGAGCGTTCAGGTACTAAAGCAGGTAACAAGGGCGGC
GAAGCTGCACTAAGCTTGCTTGAAATGGTCAATGTTCTGCAACAGCTAGAACAACAGTTGTAA

Upstream 100 bases:

>100_bases
GAAGTGACTGAATACGTAGCGGAGTAACAGGCCGAGCTTGTTAGACGTTGCACTAAGGTAAAATTAATCATTTGTATAAT
TTGCATAGGGCTGTGGGCGA

Downstream 100 bases:

>100_bases
TAGTAGGAAAAATAATGAAGCCTTCTGAGCGCCGCAAGGCCCGCCGTTTAGCCGTACAAGCCATTTATTCATGGCAACTA
AGCGGGAATAATATTGCCGA

Product: 6,7-dimethyl-8-ribityllumazine synthase

Products: NA

Alternate protein names: DMRL synthase; Lumazine synthase; Riboflavin synthase beta chain [H]

Number of amino acids: Translated: 180; Mature: 179

Protein sequence:

>180_residues
MTVVSCRHFSPKPGALAKLGKKMNVVQGNIEAKNAKVAIVISRFNSFLVESLLESALDTLKRFGQVSDENITVVRVPGAV
ELPLAARRVAASGKFDGIIALGAVIRGGTPHFDFVAGECNKGLAQIALEFDLPVAFGVLTTDTIEQAIERSGTKAGNKGG
EAALSLLEMVNVLQQLEQQL

Sequences:

>Translated_180_residues
MTVVSCRHFSPKPGALAKLGKKMNVVQGNIEAKNAKVAIVISRFNSFLVESLLESALDTLKRFGQVSDENITVVRVPGAV
ELPLAARRVAASGKFDGIIALGAVIRGGTPHFDFVAGECNKGLAQIALEFDLPVAFGVLTTDTIEQAIERSGTKAGNKGG
EAALSLLEMVNVLQQLEQQL
>Mature_179_residues
TVVSCRHFSPKPGALAKLGKKMNVVQGNIEAKNAKVAIVISRFNSFLVESLLESALDTLKRFGQVSDENITVVRVPGAVE
LPLAARRVAASGKFDGIIALGAVIRGGTPHFDFVAGECNKGLAQIALEFDLPVAFGVLTTDTIEQAIERSGTKAGNKGGE
AALSLLEMVNVLQQLEQQL

Specific function: Riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5-amino-6-(1'-D)- ribityl-amino-2,4(1H,3H)-pyrimidinedione and L-3,4-dihydrohy-2- butanone-4-phosphate via 6,7-dimethyl-8-lumazine. The beta subunit catalyzes

COG id: COG0054

COG function: function code H; Riboflavin synthase beta-chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DMRL synthase family [H]

Homologues:

Organism=Escherichia coli, GI1786617, Length=155, Percent_Identity=63.2258064516129, Blast_Score=209, Evalue=1e-55,
Organism=Saccharomyces cerevisiae, GI6324429, Length=164, Percent_Identity=31.7073170731707, Blast_Score=84, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002180 [H]

Pfam domain/function: PF00885 DMRL_synthase [H]

EC number: =2.5.1.9 [H]

Molecular weight: Translated: 19057; Mature: 18926

Theoretical pI: Translated: 8.23; Mature: 8.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVVSCRHFSPKPGALAKLGKKMNVVQGNIEAKNAKVAIVISRFNSFLVESLLESALDTL
CCEEECCCCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHH
KRFGQVSDENITVVRVPGAVELPLAARRVAASGKFDGIIALGAVIRGGTPHFDFVAGECN
HHHCCCCCCCEEEEECCCCEECCHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCEECCCCC
KGLAQIALEFDLPVAFGVLTTDTIEQAIERSGTKAGNKGGEAALSLLEMVNVLQQLEQQL
CCHHHEEEHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TVVSCRHFSPKPGALAKLGKKMNVVQGNIEAKNAKVAIVISRFNSFLVESLLESALDTL
CEEECCCCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHH
KRFGQVSDENITVVRVPGAVELPLAARRVAASGKFDGIIALGAVIRGGTPHFDFVAGECN
HHHCCCCCCCEEEEECCCCEECCHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCEECCCCC
KGLAQIALEFDLPVAFGVLTTDTIEQAIERSGTKAGNKGGEAALSLLEMVNVLQQLEQQL
CCHHHEEEHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA