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The map label for this gene is coaA [H]

Identifier: 117918642

GI number: 117918642

Start: 223327

End: 224277

Strand: Reverse

Name: coaA [H]

Synonym: Shewana3_0184

Alternate gene names: 117918642

Gene position: 224277-223327 (Counterclockwise)

Preceding gene: 117918684

Following gene: 117918639

Centisome position: 4.51

GC content: 47.53

Gene sequence:

>951_bases
ATGACGTCAAAAAATCCAATTCAAAAAGCACTCTATCTTGCCTTTGAGCGCGCGCAATGGTCTGTTTTACGGGACGCAGT
GCCGATGACACTGAGTGAACAAGACTTGGAAAATTTGCGCGGTATTAATGAGAAGGTCTCCCTCTCAGAAGTTACCGACA
TTTACTTGCCACTCAGCAGGTTACTCAATCTCATCGTAAAATCGAAGCAACAACGTGGCTTAGTCTTGGATGAGTTTCTC
GGCCAAAAACCCTCAAGTAGCCCTTATATCATTAGTATCGCCGGCAGCGTTGCCGTAGGTAAAAGTACCACAGCGCGTAT
TTTGCAAGCCTTGCTGCGCCACTGGCCTGAGCATCCTAAGGTCGATTTAGTCACTACTGATGGTTTTTTATATCCTTTGG
CTGACCTAAAGCGCAAGGGTTTACTGCAGCGTAAAGGCTTTCCCGAAAGCTACGACATGAAGATGTTGGTAGAATTTATT
TCGGCGGTAAAATCGGGGCAGGCCCATGTGAATGCGCCTATCTACTCCCACGTGACTTACGATCGTATCCGCGGCCAGCA
TCAAACGGTCTCTCAGCCCGATATTTTGATCCTAGAAGGACTCAATGTACTGCAAACCGGCTTAGATTCACCAGTAGATA
TACGCCGCCCCTTCGTCTCCGACTTTGTCGACTTCTCCATTTACGTCGATGCCGAAGAGCACTTATTAAAGCAGTGGTAT
CAGGAGCGCTTTTTGCAGTTCCGCAAAGGTGCCTTCAGTGATGAAAAGTCGTATTTTCATCACTATGCCAGCCTAACAGA
TGATGAGGCGAATGCCATTGCAGCGAAGATTTGGGACACGATCAACGGCCCCAATTTGCAACTCAATATCCAGCCGACAA
GAGAGCGGGCACATCTGATCCTGCAAAAAGGCCAGGATCACTTGATGTCCCACGTATTGTTACGCAAATAA

Upstream 100 bases:

>100_bases
TACTCAAGCGTGACCAATAAATGGGGCATCGAGAATAGATTTTATATTGTCGATACTTAAGTCATGGTGTACTGTGCGAT
CCCTAAGCCGAGGAAAGCCT

Downstream 100 bases:

>100_bases
TCTATCTTGGTCTTAAACTGATTTCACCGCCGATGTATGCCTGTGTGCCATCGGCGGTTTCAAGTAGCACTGCGCCCTGT
TCGTCGACACCGCGGCAAAT

Product: pantothenate kinase

Products: NA

Alternate protein names: Pantothenic acid kinase [H]

Number of amino acids: Translated: 316; Mature: 315

Protein sequence:

>316_residues
MTSKNPIQKALYLAFERAQWSVLRDAVPMTLSEQDLENLRGINEKVSLSEVTDIYLPLSRLLNLIVKSKQQRGLVLDEFL
GQKPSSSPYIISIAGSVAVGKSTTARILQALLRHWPEHPKVDLVTTDGFLYPLADLKRKGLLQRKGFPESYDMKMLVEFI
SAVKSGQAHVNAPIYSHVTYDRIRGQHQTVSQPDILILEGLNVLQTGLDSPVDIRRPFVSDFVDFSIYVDAEEHLLKQWY
QERFLQFRKGAFSDEKSYFHHYASLTDDEANAIAAKIWDTINGPNLQLNIQPTRERAHLILQKGQDHLMSHVLLRK

Sequences:

>Translated_316_residues
MTSKNPIQKALYLAFERAQWSVLRDAVPMTLSEQDLENLRGINEKVSLSEVTDIYLPLSRLLNLIVKSKQQRGLVLDEFL
GQKPSSSPYIISIAGSVAVGKSTTARILQALLRHWPEHPKVDLVTTDGFLYPLADLKRKGLLQRKGFPESYDMKMLVEFI
SAVKSGQAHVNAPIYSHVTYDRIRGQHQTVSQPDILILEGLNVLQTGLDSPVDIRRPFVSDFVDFSIYVDAEEHLLKQWY
QERFLQFRKGAFSDEKSYFHHYASLTDDEANAIAAKIWDTINGPNLQLNIQPTRERAHLILQKGQDHLMSHVLLRK
>Mature_315_residues
TSKNPIQKALYLAFERAQWSVLRDAVPMTLSEQDLENLRGINEKVSLSEVTDIYLPLSRLLNLIVKSKQQRGLVLDEFLG
QKPSSSPYIISIAGSVAVGKSTTARILQALLRHWPEHPKVDLVTTDGFLYPLADLKRKGLLQRKGFPESYDMKMLVEFIS
AVKSGQAHVNAPIYSHVTYDRIRGQHQTVSQPDILILEGLNVLQTGLDSPVDIRRPFVSDFVDFSIYVDAEEHLLKQWYQ
ERFLQFRKGAFSDEKSYFHHYASLTDDEANAIAAKIWDTINGPNLQLNIQPTRERAHLILQKGQDHLMSHVLLRK

Specific function: Coenzyme A (CoA) biosynthesis; first step. [C]

COG id: COG1072

COG function: function code H; Panthothenate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic pantothenate kinase family [H]

Homologues:

Organism=Escherichia coli, GI1790409, Length=305, Percent_Identity=61.9672131147541, Blast_Score=381, Evalue=1e-107,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004566
- InterPro:   IPR006083 [H]

Pfam domain/function: PF00485 PRK [H]

EC number: =2.7.1.33 [H]

Molecular weight: Translated: 36017; Mature: 35886

Theoretical pI: Translated: 8.67; Mature: 8.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSKNPIQKALYLAFERAQWSVLRDAVPMTLSEQDLENLRGINEKVSLSEVTDIYLPLSR
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHH
LLNLIVKSKQQRGLVLDEFLGQKPSSSPYIISIAGSVAVGKSTTARILQALLRHWPEHPK
HHHHHHHHHHHCCCCHHHHHCCCCCCCCEEEEECCCEEECCCHHHHHHHHHHHHCCCCCC
VDLVTTDGFLYPLADLKRKGLLQRKGFPESYDMKMLVEFISAVKSGQAHVNAPIYSHVTY
EEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCEECCCHHHHHHH
DRIRGQHQTVSQPDILILEGLNVLQTGLDSPVDIRRPFVSDFVDFSIYVDAEEHLLKQWY
HHHCCCCCCCCCCCEEEECCCHHHHHCCCCCHHHHHHHHHHHHCEEEEECHHHHHHHHHH
QERFLQFRKGAFSDEKSYFHHYASLTDDEANAIAAKIWDTINGPNLQLNIQPTRERAHLI
HHHHHHHHCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHH
LQKGQDHLMSHVLLRK
HHCCHHHHHHHHHHCC
>Mature Secondary Structure 
TSKNPIQKALYLAFERAQWSVLRDAVPMTLSEQDLENLRGINEKVSLSEVTDIYLPLSR
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHH
LLNLIVKSKQQRGLVLDEFLGQKPSSSPYIISIAGSVAVGKSTTARILQALLRHWPEHPK
HHHHHHHHHHHCCCCHHHHHCCCCCCCCEEEEECCCEEECCCHHHHHHHHHHHHCCCCCC
VDLVTTDGFLYPLADLKRKGLLQRKGFPESYDMKMLVEFISAVKSGQAHVNAPIYSHVTY
EEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCEECCCHHHHHHH
DRIRGQHQTVSQPDILILEGLNVLQTGLDSPVDIRRPFVSDFVDFSIYVDAEEHLLKQWY
HHHCCCCCCCCCCCEEEECCCHHHHHCCCCCHHHHHHHHHHHHCEEEEECHHHHHHHHHH
QERFLQFRKGAFSDEKSYFHHYASLTDDEANAIAAKIWDTINGPNLQLNIQPTRERAHLI
HHHHHHHHCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHH
LQKGQDHLMSHVLLRK
HHCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA