| Definition | Listeria welshimeri serovar 6b str. SLCC5334, complete genome. |
|---|---|
| Accession | NC_008555 |
| Length | 2,814,130 |
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The map label for this gene is parE [H]
Identifier: 116872719
GI number: 116872719
Start: 1291530
End: 1293497
Strand: Direct
Name: parE [H]
Synonym: lwe1303
Alternate gene names: 116872719
Gene position: 1291530-1293497 (Clockwise)
Preceding gene: 116872718
Following gene: 116872720
Centisome position: 45.89
GC content: 40.35
Gene sequence:
>1968_bases ATGAATCGGAATGAGTATAATGATGATTCTATTCAGGTGCTTGAAGGACTGGAAGCGGTCCGGAAACGCCCAGCGATGTA TATTGGCTCAACAGATGTACGCGGGTTGCACCATTTAGTATATGAAATTGTAGATAACTCGGTCGATGAGACCCTTGCAG GATTTGGTAAGAAAATTGTGGTAACACTTCATGATGATGGTAGCGTTAGTGTCAGTGATGAAGGACGCGGAATGCCTGTT GGAATGCATAAAACTGGGAAATCCACAGTAGAGGTTATTTTAACTGTACTTCATGCTGGTGGTAAGTTTGGGCAAGAAGG CGGTTATAAAACAAGTGGAGGACTGCATGGTGTTGGTTCCTCTGTTGTAAATGCATTATCAGAATGGTTAGTTGTTACCA TTAATCGTGACGGTGCGACATATCAGCAAAAATTTAAAGACGGCGGAAAGCCAGATGGTACGCTTAAAAAAATCGGTAAA TCAAAAGCCACTGGGACGACAATTCGTTTTAAACCAGATCCAACTATTTTTCCAACTACTTCCTTTAATTATGAAACCTT ATCTGAACGTTTAAGAGAATCTGCATTTCTTCTAAAAGGCATGTTGATTCAATTAGTGGATGAACGAGTTGGAATGGCAG AGTCTTTCCATTTTGAAGAGGGTGTGAAAAACTTTGTAGAATATATTAATGAAGGAAAAGATGTACTTCACCCAGTAGCC AGTTTTGAAGGGGAAAATGCAACCATTGAAGTAGAAATGGCGTTCCAATTCAATGATGGTTATTCAGAAAACATCTTGAG CTTTGTTAATAATGTGCGAACACGTGGAGCAGGCTCGCATGAATCAGGAATGAAAGCTGCGATGACACGTATTTTCAATG ATTATGCTCGTCGCGTTAATCTTTTAAAAGAAAAAGATAAAAATCTCGAAGGTAGCGATATTCGCGAAGGTTTATCCGCT GTACTTTCTATTCGTGTGCCAGAAAAAATTCTCCAATTCGAAGGTCAAACGAAAGAAAAATTAGGGACACAGGAAGCGCG TCAGGCAGTGGATGCTGTTGTGGCTGAACATTTAGCTTACTTCCTCGCTGAAAACCCTGAAACGAGCTCTCTTCTTGTTA AAAAGGCAGTTAAAGCAAGAGAAGCAAGGGAAGCTGCTAGAAAGGCGCGTGAAGAAACACGTAATGGCAAGAAAAAGAAA CGTTCAGAAACGCTTCTGTCTGGTAAACTAACACCAGCTCAATCACGCAATCCTAACAAAAATGAACTTTATCTTGTCGA AGGGGACTCTGCGGGAGGATCTGCCAAACAAGGTCGTGATCGTCGCTTCCAAGCAATTTTGCCACTTCGAGGAAAAGTAA TCAATACAGAAAAAGCAAAACTACAAGACATCTTAAAAAACGAAGAAATTAGCACTATTATTCATACAGTTGGTGCTGGA GTTGGTACGGAGTTTGATGTAGAAGATTGTAACTATGACAAAGTTGTTATTATGACCGATGCTGATACAGATGGTGCGCA TATTCAAGTACTATTACTAACATTCTTTTATCGTTATATGCGACCACTTGTTGAGGCTGGTAAAGTCTTTATCGCATTAC CGCCACTTTATAAAGTAAGTCGTGGTTCTGGGAAAAAAGAAGTGATTGAATATGCCTGGACGGATGAGGAGTTAGATTCT GCTATCCAAAAAATTGGTAAAGGCTACATGATTCAACGTTATAAAGGTCTTGGTGAAATGAATGCAGATCAACTTTGGGA AACAACAATGAATCCAGACACACGTACTTTGATTCGAGTGCGCGTAGATGATTCCGCACGCGCTGAACGACGCGTAGCAA CACTGATGGGTGACAAAGTAGAGCCAAGACGTCAGTGGATTGAAAAGCATGTCGAGTTTTCTATGGAAGATAACCAAAAT ATTTTAGAAAATGAAAACATGATGGTTGAGGAGGCGAAAGACATTTGA
Upstream 100 bases:
>100_bases CACTTTATTAATTAGCTAGTTAATGCTATTCTGATAAAGTGGTTTTAAGCGAATAAACTATAATAGTTGTAGATTGATGG AATGAAGGGAGTTTTGACAT
Downstream 100 bases:
>100_bases GTAATCCAGAACAACATATCCAAGACTTAGCGCTTGAAGAAGTTATGGGCGACCGTTTTGGTAGGTATAGTAAATATATT ATTCAAGAACGTGCGCTTCC
Product: DNA topoisomerase IV subunit B
Products: NA
Alternate protein names: Topoisomerase IV subunit B [H]
Number of amino acids: Translated: 655; Mature: 655
Protein sequence:
>655_residues MNRNEYNDDSIQVLEGLEAVRKRPAMYIGSTDVRGLHHLVYEIVDNSVDETLAGFGKKIVVTLHDDGSVSVSDEGRGMPV GMHKTGKSTVEVILTVLHAGGKFGQEGGYKTSGGLHGVGSSVVNALSEWLVVTINRDGATYQQKFKDGGKPDGTLKKIGK SKATGTTIRFKPDPTIFPTTSFNYETLSERLRESAFLLKGMLIQLVDERVGMAESFHFEEGVKNFVEYINEGKDVLHPVA SFEGENATIEVEMAFQFNDGYSENILSFVNNVRTRGAGSHESGMKAAMTRIFNDYARRVNLLKEKDKNLEGSDIREGLSA VLSIRVPEKILQFEGQTKEKLGTQEARQAVDAVVAEHLAYFLAENPETSSLLVKKAVKAREAREAARKAREETRNGKKKK RSETLLSGKLTPAQSRNPNKNELYLVEGDSAGGSAKQGRDRRFQAILPLRGKVINTEKAKLQDILKNEEISTIIHTVGAG VGTEFDVEDCNYDKVVIMTDADTDGAHIQVLLLTFFYRYMRPLVEAGKVFIALPPLYKVSRGSGKKEVIEYAWTDEELDS AIQKIGKGYMIQRYKGLGEMNADQLWETTMNPDTRTLIRVRVDDSARAERRVATLMGDKVEPRRQWIEKHVEFSMEDNQN ILENENMMVEEAKDI
Sequences:
>Translated_655_residues MNRNEYNDDSIQVLEGLEAVRKRPAMYIGSTDVRGLHHLVYEIVDNSVDETLAGFGKKIVVTLHDDGSVSVSDEGRGMPV GMHKTGKSTVEVILTVLHAGGKFGQEGGYKTSGGLHGVGSSVVNALSEWLVVTINRDGATYQQKFKDGGKPDGTLKKIGK SKATGTTIRFKPDPTIFPTTSFNYETLSERLRESAFLLKGMLIQLVDERVGMAESFHFEEGVKNFVEYINEGKDVLHPVA SFEGENATIEVEMAFQFNDGYSENILSFVNNVRTRGAGSHESGMKAAMTRIFNDYARRVNLLKEKDKNLEGSDIREGLSA VLSIRVPEKILQFEGQTKEKLGTQEARQAVDAVVAEHLAYFLAENPETSSLLVKKAVKAREAREAARKAREETRNGKKKK RSETLLSGKLTPAQSRNPNKNELYLVEGDSAGGSAKQGRDRRFQAILPLRGKVINTEKAKLQDILKNEEISTIIHTVGAG VGTEFDVEDCNYDKVVIMTDADTDGAHIQVLLLTFFYRYMRPLVEAGKVFIALPPLYKVSRGSGKKEVIEYAWTDEELDS AIQKIGKGYMIQRYKGLGEMNADQLWETTMNPDTRTLIRVRVDDSARAERRVATLMGDKVEPRRQWIEKHVEFSMEDNQN ILENENMMVEEAKDI >Mature_655_residues MNRNEYNDDSIQVLEGLEAVRKRPAMYIGSTDVRGLHHLVYEIVDNSVDETLAGFGKKIVVTLHDDGSVSVSDEGRGMPV GMHKTGKSTVEVILTVLHAGGKFGQEGGYKTSGGLHGVGSSVVNALSEWLVVTINRDGATYQQKFKDGGKPDGTLKKIGK SKATGTTIRFKPDPTIFPTTSFNYETLSERLRESAFLLKGMLIQLVDERVGMAESFHFEEGVKNFVEYINEGKDVLHPVA SFEGENATIEVEMAFQFNDGYSENILSFVNNVRTRGAGSHESGMKAAMTRIFNDYARRVNLLKEKDKNLEGSDIREGLSA VLSIRVPEKILQFEGQTKEKLGTQEARQAVDAVVAEHLAYFLAENPETSSLLVKKAVKAREAREAARKAREETRNGKKKK RSETLLSGKLTPAQSRNPNKNELYLVEGDSAGGSAKQGRDRRFQAILPLRGKVINTEKAKLQDILKNEEISTIIHTVGAG VGTEFDVEDCNYDKVVIMTDADTDGAHIQVLLLTFFYRYMRPLVEAGKVFIALPPLYKVSRGSGKKEVIEYAWTDEELDS AIQKIGKGYMIQRYKGLGEMNADQLWETTMNPDTRTLIRVRVDDSARAERRVATLMGDKVEPRRQWIEKHVEFSMEDNQN ILENENMMVEEAKDI
Specific function: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule [H]
COG id: COG0187
COG function: function code L; Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the type II topoisomerase family [H]
Homologues:
Organism=Homo sapiens, GI19913406, Length=616, Percent_Identity=24.512987012987, Blast_Score=109, Evalue=1e-23, Organism=Homo sapiens, GI19913408, Length=682, Percent_Identity=23.3137829912023, Blast_Score=104, Evalue=3e-22, Organism=Escherichia coli, GI48994957, Length=561, Percent_Identity=50.445632798574, Blast_Score=506, Evalue=1e-144, Organism=Escherichia coli, GI1789408, Length=640, Percent_Identity=37.96875, Blast_Score=401, Evalue=1e-113, Organism=Caenorhabditis elegans, GI17535065, Length=672, Percent_Identity=24.5535714285714, Blast_Score=130, Evalue=3e-30, Organism=Caenorhabditis elegans, GI212645845, Length=604, Percent_Identity=25.1655629139073, Blast_Score=106, Evalue=4e-23, Organism=Caenorhabditis elegans, GI212645657, Length=204, Percent_Identity=29.9019607843137, Blast_Score=75, Evalue=1e-13, Organism=Saccharomyces cerevisiae, GI6324241, Length=683, Percent_Identity=25.3294289897511, Blast_Score=101, Evalue=3e-22, Organism=Drosophila melanogaster, GI17136538, Length=678, Percent_Identity=25.5162241887906, Blast_Score=128, Evalue=1e-29,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR003594 - InterPro: IPR020568 - InterPro: IPR014721 - InterPro: IPR001241 - InterPro: IPR013759 - InterPro: IPR002288 - InterPro: IPR013506 - InterPro: IPR013760 - InterPro: IPR018522 - InterPro: IPR005740 [H]
Pfam domain/function: PF00204 DNA_gyraseB; PF00986 DNA_gyraseB_C; PF02518 HATPase_c [H]
EC number: 5.99.1.-
Molecular weight: Translated: 73060; Mature: 73060
Theoretical pI: Translated: 6.48; Mature: 6.48
Prosite motif: PS00177 TOPOISOMERASE_II
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.2 %Cys (Translated Protein) 2.7 %Met (Translated Protein) 2.9 %Cys+Met (Translated Protein) 0.2 %Cys (Mature Protein) 2.7 %Met (Mature Protein) 2.9 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MNRNEYNDDSIQVLEGLEAVRKRPAMYIGSTDVRGLHHLVYEIVDNSVDETLAGFGKKIV CCCCCCCCHHHHHHHHHHHHHHCCCEEECCCCHHHHHHHHHHHHHCHHHHHHHCCCCEEE VTLHDDGSVSVSDEGRGMPVGMHKTGKSTVEVILTVLHAGGKFGQEGGYKTSGGLHGVGS EEEECCCCEEECCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHH SVVNALSEWLVVTINRDGATYQQKFKDGGKPDGTLKKIGKSKATGTTIRFKPDPTIFPTT HHHHHHHCCEEEEECCCCCHHHHHHHCCCCCCHHHHHHCCCCCCCCEEEECCCCCCCCCC SFNYETLSERLRESAFLLKGMLIQLVDERVGMAESFHFEEGVKNFVEYINEGKDVLHPVA CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCHHHHHHHH SFEGENATIEVEMAFQFNDGYSENILSFVNNVRTRGAGSHESGMKAAMTRIFNDYARRVN HCCCCCCEEEEEEEEEECCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH LLKEKDKNLEGSDIREGLSAVLSIRVPEKILQFEGQTKEKLGTQEARQAVDAVVAEHLAY HHHHHCCCCCCHHHHHHHHHHHHHCCCHHHHHCCCCCHHHCCHHHHHHHHHHHHHHHHHH FLAENPETSSLLVKKAVKAREAREAARKAREETRNGKKKKRSETLLSGKLTPAQSRNPNK HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCC NELYLVEGDSAGGSAKQGRDRRFQAILPLRGKVINTEKAKLQDILKNEEISTIIHTVGAG CEEEEEECCCCCCCCCCCCCCHHHEECCCCCEEECCHHHHHHHHHCCCHHHHHHHHHCCC VGTEFDVEDCNYDKVVIMTDADTDGAHIQVLLLTFFYRYMRPLVEAGKVFIALPPLYKVS CCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCC RGSGKKEVIEYAWTDEELDSAIQKIGKGYMIQRYKGLGEMNADQLWETTMNPDTRTLIRV CCCCHHHHHHHHCCHHHHHHHHHHHCCCCEEHHHHCCCCCCHHHHHHHCCCCCCEEEEEE RVDDSARAERRVATLMGDKVEPRRQWIEKHVEFSMEDNQNILENENMMVEEAKDI EECCCHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCHHHCCCEEHHHHCCC >Mature Secondary Structure MNRNEYNDDSIQVLEGLEAVRKRPAMYIGSTDVRGLHHLVYEIVDNSVDETLAGFGKKIV CCCCCCCCHHHHHHHHHHHHHHCCCEEECCCCHHHHHHHHHHHHHCHHHHHHHCCCCEEE VTLHDDGSVSVSDEGRGMPVGMHKTGKSTVEVILTVLHAGGKFGQEGGYKTSGGLHGVGS EEEECCCCEEECCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHH SVVNALSEWLVVTINRDGATYQQKFKDGGKPDGTLKKIGKSKATGTTIRFKPDPTIFPTT HHHHHHHCCEEEEECCCCCHHHHHHHCCCCCCHHHHHHCCCCCCCCEEEECCCCCCCCCC SFNYETLSERLRESAFLLKGMLIQLVDERVGMAESFHFEEGVKNFVEYINEGKDVLHPVA CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCHHHHHHHH SFEGENATIEVEMAFQFNDGYSENILSFVNNVRTRGAGSHESGMKAAMTRIFNDYARRVN HCCCCCCEEEEEEEEEECCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH LLKEKDKNLEGSDIREGLSAVLSIRVPEKILQFEGQTKEKLGTQEARQAVDAVVAEHLAY HHHHHCCCCCCHHHHHHHHHHHHHCCCHHHHHCCCCCHHHCCHHHHHHHHHHHHHHHHHH FLAENPETSSLLVKKAVKAREAREAARKAREETRNGKKKKRSETLLSGKLTPAQSRNPNK HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCC NELYLVEGDSAGGSAKQGRDRRFQAILPLRGKVINTEKAKLQDILKNEEISTIIHTVGAG CEEEEEECCCCCCCCCCCCCCHHHEECCCCCEEECCHHHHHHHHHCCCHHHHHHHHHCCC VGTEFDVEDCNYDKVVIMTDADTDGAHIQVLLLTFFYRYMRPLVEAGKVFIALPPLYKVS CCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCC RGSGKKEVIEYAWTDEELDSAIQKIGKGYMIQRYKGLGEMNADQLWETTMNPDTRTLIRV CCCCHHHHHHHHCCHHHHHHHHHHHCCCCEEHHHHCCCCCCHHHHHHHCCCCCCEEEEEE RVDDSARAERRVATLMGDKVEPRRQWIEKHVEFSMEDNQNILENENMMVEEAKDI EECCCHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCHHHCCCEEHHHHCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 8969507; 9539793; 9384377 [H]