Click here to switch to the map view.

The map label for this gene is sipY [H]

Identifier: 116872703

GI number: 116872703

Start: 1276865

End: 1277434

Strand: Direct

Name: sipY [H]

Synonym: lwe1287

Alternate gene names: 116872703

Gene position: 1276865-1277434 (Clockwise)

Preceding gene: 116872702

Following gene: 116872704

Centisome position: 45.37

GC content: 36.67

Gene sequence:

>570_bases
ATGGTGGATAACATGGAAGAAGAACCCAAGAAAAAAAGTGGGTTCCAACAATTAATGAGTTGGGTACTTGTCATCGTTGC
AGCACTCGCGATTGCACTTGTTGTGAGAAACTTTGTGATTGCCCCAGTAAAAGTAGAAGGAACATCTATGGTTCCAACCT
ATCAAGATGGTGACCGAATTTTTATTGAAAAAATAACGAATCCTAATCGTTTTGATATTATTGTATTTGATGAACCACCA
ATGATTGGAACTGGAGAACATTTCATTAAACGAGTAATCGGTGTTCCAGGAGATAAAATCGCTTTTAAAAATGGAGAATT
ATATTTAAATGGTAAACGTAAAGTAGAGAGTTATCTGCCAGATGGAACATTAACATTATGGAATCCTGATCCCACTCAAA
AACCTTATATTGCTGACTACACACTCAAAGATATGACGGGTGAAAGTACTGTGCCAAAAGGAAAACTGTTTGTTTTAGGT
GATAATCGCGGTGGAAGCTCAGATAGCCGTGTTTTTGGATTTATTGATGATTCAACAGTCAACGGTAAAGTTTTGCAATT
CGGGAAATAA

Upstream 100 bases:

>100_bases
AGGCTTTATTTCTCAAGAAAGTGTGCTTGGGAAAGTTATATCATTCGGCAAATCTTTAAAACGATAATTAAAGTTGCAAA
GAGCCAAGGAGGAGACATAG

Downstream 100 bases:

>100_bases
TTGGAAGTCCGTGAAAGTTTTTTTCACGGCTTTCTCTATTAAATGAAAGATTTTTCGTTTATAATAAGACTGTTAGTAAA
AAAATAGGGCGGTGCAGTTT

Product: signal peptidase I

Products: NA

Alternate protein names: SPase I; Leader peptidase I [H]

Number of amino acids: Translated: 189; Mature: 189

Protein sequence:

>189_residues
MVDNMEEEPKKKSGFQQLMSWVLVIVAALAIALVVRNFVIAPVKVEGTSMVPTYQDGDRIFIEKITNPNRFDIIVFDEPP
MIGTGEHFIKRVIGVPGDKIAFKNGELYLNGKRKVESYLPDGTLTLWNPDPTQKPYIADYTLKDMTGESTVPKGKLFVLG
DNRGGSSDSRVFGFIDDSTVNGKVLQFGK

Sequences:

>Translated_189_residues
MVDNMEEEPKKKSGFQQLMSWVLVIVAALAIALVVRNFVIAPVKVEGTSMVPTYQDGDRIFIEKITNPNRFDIIVFDEPP
MIGTGEHFIKRVIGVPGDKIAFKNGELYLNGKRKVESYLPDGTLTLWNPDPTQKPYIADYTLKDMTGESTVPKGKLFVLG
DNRGGSSDSRVFGFIDDSTVNGKVLQFGK
>Mature_189_residues
MVDNMEEEPKKKSGFQQLMSWVLVIVAALAIALVVRNFVIAPVKVEGTSMVPTYQDGDRIFIEKITNPNRFDIIVFDEPP
MIGTGEHFIKRVIGVPGDKIAFKNGELYLNGKRKVESYLPDGTLTLWNPDPTQKPYIADYTLKDMTGESTVPKGKLFVLG
DNRGGSSDSRVFGFIDDSTVNGKVLQFGK

Specific function: Unknown

COG id: COG0681

COG function: function code U; Signal peptidase I

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S26 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000223
- InterPro:   IPR019758
- InterPro:   IPR019757
- InterPro:   IPR019756
- InterPro:   IPR019759
- InterPro:   IPR015927
- InterPro:   IPR011056 [H]

Pfam domain/function: PF00717 Peptidase_S24 [H]

EC number: =3.4.21.89 [H]

Molecular weight: Translated: 20988; Mature: 20988

Theoretical pI: Translated: 5.99; Mature: 5.99

Prosite motif: PS00760 SPASE_I_2 ; PS00761 SPASE_I_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVDNMEEEPKKKSGFQQLMSWVLVIVAALAIALVVRNFVIAPVKVEGTSMVPTYQDGDRI
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCEECCCCCCCCEE
FIEKITNPNRFDIIVFDEPPMIGTGEHFIKRVIGVPGDKIAFKNGELYLNGKRKVESYLP
EEEECCCCCEEEEEEECCCCCCCCHHHHHHHHHCCCCCEEEEECCEEEECCCHHHHHHCC
DGTLTLWNPDPTQKPYIADYTLKDMTGESTVPKGKLFVLGDNRGGSSDSRVFGFIDDSTV
CCEEEEECCCCCCCCEEECEEECCCCCCCCCCCCEEEEEECCCCCCCCCEEEEEECCCCC
NGKVLQFGK
CCEEEEECC
>Mature Secondary Structure
MVDNMEEEPKKKSGFQQLMSWVLVIVAALAIALVVRNFVIAPVKVEGTSMVPTYQDGDRI
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCEECCCCCCCCEE
FIEKITNPNRFDIIVFDEPPMIGTGEHFIKRVIGVPGDKIAFKNGELYLNGKRKVESYLP
EEEECCCCCEEEEEEECCCCCCCCHHHHHHHHHCCCCCEEEEECCEEEECCCHHHHHHCC
DGTLTLWNPDPTQKPYIADYTLKDMTGESTVPKGKLFVLGDNRGGSSDSRVFGFIDDSTV
CCEEEEECCCCCCCCEEECEEECCCCCCCCCCCCEEEEEECCCCCCCCCEEEEEECCCCC
NGKVLQFGK
CCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377; 9823656 [H]