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The map label for this gene is sipX [H]

Identifier: 116872702

GI number: 116872702

Start: 1276265

End: 1276831

Strand: Direct

Name: sipX [H]

Synonym: lwe1286

Alternate gene names: 116872702

Gene position: 1276265-1276831 (Clockwise)

Preceding gene: 116872701

Following gene: 116872703

Centisome position: 45.35

GC content: 32.63

Gene sequence:

>567_bases
ATGAAAAGTGAAAATAAATTTTTTTCTGGAGCTTTTGGATGGATAAAAATAATTATCATTGCGCTAGTTCTAGCTTTTGG
TATTCGTTATTTTTTAATTTCTCCAGTTACTGTTAATGGAGCATCGATGAACCCGACTCTGCATGATGGGGAGCATTTAT
TTATTAATAAAGTATCAGATCCAAAACGGTTTGATATTATTGTGTTTCCAGCTCCTGACGAAGAAAATGCTGAATATATT
AAACGTGTCATTGGTCTTCCAGGAGATAAAGTTGAATATAAAGAGGATCAACTTTATATTAACGACAAAAAATATGACGA
ACCATATTTAGATTCAGAAAAAGATGCTTTAAAAAGTGGTTATTTAACTACGGATGCAAATGGGGATCCTAATTTTACCA
TGGCTGAGATTAAAGGTTCCAATGGTTCACTTATTGTTCCAGAAGGTCAATTGTTTGTGTTAGGTGATAATCGTCAAGTA
AGTAAAGATAGTCGGTATATAGGCTTTATTTCTCAAGAAAGTGTGCTTGGGAAAGTTATATCATTCGGCAAATCTTTAAA
ACGATAA

Upstream 100 bases:

>100_bases
TTGGCGCGCATTTTTTCTGTCAAACCAGCTTGTTTCATTACACCATCTGGTGGGTTTCGTGCTATACTTTAGTAATATTA
ATTGGAGAGGATAAAAAGAC

Downstream 100 bases:

>100_bases
TTAAAGTTGCAAAGAGCCAAGGAGGAGACATAGATGGTGGATAACATGGAAGAAGAACCCAAGAAAAAAAGTGGGTTCCA
ACAATTAATGAGTTGGGTAC

Product: signal peptidase I

Products: NA

Alternate protein names: SPase I; Leader peptidase I [H]

Number of amino acids: Translated: 188; Mature: 188

Protein sequence:

>188_residues
MKSENKFFSGAFGWIKIIIIALVLAFGIRYFLISPVTVNGASMNPTLHDGEHLFINKVSDPKRFDIIVFPAPDEENAEYI
KRVIGLPGDKVEYKEDQLYINDKKYDEPYLDSEKDALKSGYLTTDANGDPNFTMAEIKGSNGSLIVPEGQLFVLGDNRQV
SKDSRYIGFISQESVLGKVISFGKSLKR

Sequences:

>Translated_188_residues
MKSENKFFSGAFGWIKIIIIALVLAFGIRYFLISPVTVNGASMNPTLHDGEHLFINKVSDPKRFDIIVFPAPDEENAEYI
KRVIGLPGDKVEYKEDQLYINDKKYDEPYLDSEKDALKSGYLTTDANGDPNFTMAEIKGSNGSLIVPEGQLFVLGDNRQV
SKDSRYIGFISQESVLGKVISFGKSLKR
>Mature_188_residues
MKSENKFFSGAFGWIKIIIIALVLAFGIRYFLISPVTVNGASMNPTLHDGEHLFINKVSDPKRFDIIVFPAPDEENAEYI
KRVIGLPGDKVEYKEDQLYINDKKYDEPYLDSEKDALKSGYLTTDANGDPNFTMAEIKGSNGSLIVPEGQLFVLGDNRQV
SKDSRYIGFISQESVLGKVISFGKSLKR

Specific function: Unknown

COG id: COG0681

COG function: function code U; Signal peptidase I

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S26 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000223
- InterPro:   IPR019758
- InterPro:   IPR019757
- InterPro:   IPR019756
- InterPro:   IPR019759
- InterPro:   IPR015927
- InterPro:   IPR011056 [H]

Pfam domain/function: PF00717 Peptidase_S24 [H]

EC number: =3.4.21.89 [H]

Molecular weight: Translated: 21036; Mature: 21036

Theoretical pI: Translated: 5.35; Mature: 5.35

Prosite motif: PS00501 SPASE_I_1 ; PS00760 SPASE_I_2 ; PS00761 SPASE_I_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSENKFFSGAFGWIKIIIIALVLAFGIRYFLISPVTVNGASMNPTLHDGEHLFINKVSD
CCCCCCEECCHHHHHHHHHHHHHHHHHHHHHEECCEEECCCCCCCCEECCCEEEEEECCC
PKRFDIIVFPAPDEENAEYIKRVIGLPGDKVEYKEDQLYINDKKYDEPYLDSEKDALKSG
CCEEEEEEEECCCCCCHHHHHHHHCCCCCCCEECCCEEEECCCCCCCCCCCCCHHHHHCC
YLTTDANGDPNFTMAEIKGSNGSLIVPEGQLFVLGDNRQVSKDSRYIGFISQESVLGKVI
CEEECCCCCCCEEEEEEECCCCCEEEECCEEEEEECCCCCCCCCCEEEEECHHHHHHHHH
SFGKSLKR
HHHHHHCC
>Mature Secondary Structure
MKSENKFFSGAFGWIKIIIIALVLAFGIRYFLISPVTVNGASMNPTLHDGEHLFINKVSD
CCCCCCEECCHHHHHHHHHHHHHHHHHHHHHEECCEEECCCCCCCCEECCCEEEEEECCC
PKRFDIIVFPAPDEENAEYIKRVIGLPGDKVEYKEDQLYINDKKYDEPYLDSEKDALKSG
CCEEEEEEEECCCCCCHHHHHHHHCCCCCCCEECCCEEEECCCCCCCCCCCCCHHHHHCC
YLTTDANGDPNFTMAEIKGSNGSLIVPEGQLFVLGDNRQVSKDSRYIGFISQESVLGKVI
CEEECCCCCCCEEEEEEECCCCCEEEECCEEEEEECCCCCCCCCCEEEEECHHHHHHHHH
SFGKSLKR
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA