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The map label for this gene is cbiT [H]

Identifier: 116872569

GI number: 116872569

Start: 1162846

End: 1163415

Strand: Direct

Name: cbiT [H]

Synonym: lwe1153

Alternate gene names: 116872569

Gene position: 1162846-1163415 (Clockwise)

Preceding gene: 116872568

Following gene: 116872570

Centisome position: 41.32

GC content: 37.89

Gene sequence:

>570_bases
ATGAAAGATGAAGTATTTATTCGTGGCAAAGTTCCAATGACAAAAGCAGAGGTTCGAGCGGCAAGTATCGATTTACTTGG
ATTAGATGAAACATGTAAAAAATTACTTGATGTTGGTGCCGGAACTGGGAGTGTGGGACTTCAAGTTGCTTGTAATTTTC
CGGAAATCGAAGTGACTGCAATAGAGCGCAATCCGGTTGCAGTGGACTTAATCAAACGAAATCAAGTGAAATTTGGTCTA
GAAAATGTAAAAGTCATAGAAGCTTACGCGCCAATCGAATTAAATGAAAATGAAAAGTTTGATGCTATTTTTATTGGTGG
CAGCGGTGGAAATTTAACCGAAATTATTGACTGGTCACTGGCGCATTTGAATCCCAGTGGACGTTTAGTACTTAATTTTA
TTTTGCTGGAAAATGCGCTAACTGCAATGAACCATTTAGAAAAATTATCTGTGTACGAATTAATAATGAAGCAAATCCAA
GTTTCGAGTTGGCATAAACTTGGAGCGGGACACTATTTTGAACCACAAAATCCAACCGTGATTATCGGCTGTAAAAAACT
AGAGGAGTGA

Upstream 100 bases:

>100_bases
TTTATTGGTGAAAATTTAAGCGCTAAAGAGGAACGAATTCACAAGTTAAGACCAGCCGAAGTTGCTAAAAAATACGATAT
GAATGTAGTGGTGATTGTTG

Downstream 100 bases:

>100_bases
AGAAAATGGCAGAAGTACATTTCGTCGGAGCAGGACCAGGAGATAAAGAATTAATCACACTAAAAGGATATCAACTATTA
AAAGAAGCAGATGTTGTAAT

Product: cobalt-precorrin-6Y C(15)-methyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 189; Mature: 189

Protein sequence:

>189_residues
MKDEVFIRGKVPMTKAEVRAASIDLLGLDETCKKLLDVGAGTGSVGLQVACNFPEIEVTAIERNPVAVDLIKRNQVKFGL
ENVKVIEAYAPIELNENEKFDAIFIGGSGGNLTEIIDWSLAHLNPSGRLVLNFILLENALTAMNHLEKLSVYELIMKQIQ
VSSWHKLGAGHYFEPQNPTVIIGCKKLEE

Sequences:

>Translated_189_residues
MKDEVFIRGKVPMTKAEVRAASIDLLGLDETCKKLLDVGAGTGSVGLQVACNFPEIEVTAIERNPVAVDLIKRNQVKFGL
ENVKVIEAYAPIELNENEKFDAIFIGGSGGNLTEIIDWSLAHLNPSGRLVLNFILLENALTAMNHLEKLSVYELIMKQIQ
VSSWHKLGAGHYFEPQNPTVIIGCKKLEE
>Mature_189_residues
MKDEVFIRGKVPMTKAEVRAASIDLLGLDETCKKLLDVGAGTGSVGLQVACNFPEIEVTAIERNPVAVDLIKRNQVKFGL
ENVKVIEAYAPIELNENEKFDAIFIGGSGGNLTEIIDWSLAHLNPSGRLVLNFILLENALTAMNHLEKLSVYELIMKQIQ
VSSWHKLGAGHYFEPQNPTVIIGCKKLEE

Specific function: Probably catalyzes the methylation of either C-15 or C-5 in cobalt-precorrin-6Y to form cobalt-precorrin-7W. Methylation of C-15 would probably be followed by a spontaneous decarboxylation of C-12 [H]

COG id: COG2242

COG function: function code H; Precorrin-6B methylase 2

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. Bacterial-type CbiT family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014008
- InterPro:   IPR007848 [H]

Pfam domain/function: PF05175 MTS [H]

EC number: 1.-.-.-

Molecular weight: Translated: 20829; Mature: 20829

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDEVFIRGKVPMTKAEVRAASIDLLGLDETCKKLLDVGAGTGSVGLQVACNFPEIEVTA
CCCCEEEECCCCCCHHHHEEEEEEEEECHHHHHHHHHCCCCCCCCCEEEEECCCCEEEEE
IERNPVAVDLIKRNQVKFGLENVKVIEAYAPIELNENEKFDAIFIGGSGGNLTEIIDWSL
EECCCEEEEEEECCCEEECCCCEEEEEEECCEEECCCCCEEEEEEECCCCCCHHHEEEEE
AHLNPSGRLVLNFILLENALTAMNHLEKLSVYELIMKQIQVSSWHKLGAGHYFEPQNPTV
EEECCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCCCCCCCCEE
IIGCKKLEE
EEEECCCCC
>Mature Secondary Structure
MKDEVFIRGKVPMTKAEVRAASIDLLGLDETCKKLLDVGAGTGSVGLQVACNFPEIEVTA
CCCCEEEECCCCCCHHHHEEEEEEEEECHHHHHHHHHCCCCCCCCCEEEEECCCCEEEEE
IERNPVAVDLIKRNQVKFGLENVKVIEAYAPIELNENEKFDAIFIGGSGGNLTEIIDWSL
EECCCEEEEEEECCCEEECCCCEEEEEEECCEEECCCCCEEEEEEECCCCCCHHHEEEEE
AHLNPSGRLVLNFILLENALTAMNHLEKLSVYELIMKQIQVSSWHKLGAGHYFEPQNPTV
EEECCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCCCCCCCCEE
IIGCKKLEE
EEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]