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The map label for this gene is cbiE [H]

Identifier: 116872568

GI number: 116872568

Start: 1162260

End: 1162856

Strand: Direct

Name: cbiE [H]

Synonym: lwe1152

Alternate gene names: 116872568

Gene position: 1162260-1162856 (Clockwise)

Preceding gene: 116872567

Following gene: 116872569

Centisome position: 41.3

GC content: 35.68

Gene sequence:

>597_bases
ATGATTACGATTGTTGGAATTGGGCCAGGAGATACGAATTTGCTAATAAATGAAGCAAGACAGGCTTTAAGTTCGGCAGA
TACAGTTTATGGATCAAACAGGCAATTGCAAGAAATTGCGAATTTAACTACTGCAACTCCAATACTTTTACCAAAAAAAT
TAGCTGATTTGACAAACATTCCTCATCAAGATAAAAATGTGGTGATTCTAGCATCCGGAGACCCACTGTTATACGGAATT
GGTAACTGGGCGATAGCAAATTTTTCGGAGGATATCCGGGTTATTCCTGGTATCAGTGCTATCCAAATGATGTTTCACAA
AATCAAATTACCAATGAATGATTGTTTTATTACGAGCAGCCATGGGAAAACACCAAACTTCGACTTTTTATTACAGCATG
AAAAAGTCGCAATGGTGACGGATACGATTATTGGACCATATGAAATAGCTGCTGAAATTTTAAAACGAAATTTAAACAAA
ATCATTTTTATTGGTGAAAATTTAAGCGCTAAAGAGGAACGAATTCACAAGTTAAGACCAGCCGAAGTTGCTAAAAAATA
CGATATGAATGTAGTGGTGATTGTTGATGAAAGATGA

Upstream 100 bases:

>100_bases
TTACAAAACCAAGTGTAGAAATTGATGTGGTTACTTTTTCGACGGAGCGTGGATTGCTTGCTACAACGAAAGATATCGAT
GTATTGCGGGAGGAATGGCA

Downstream 100 bases:

>100_bases
AGTATTTATTCGTGGCAAAGTTCCAATGACAAAAGCAGAGGTTCGAGCGGCAAGTATCGATTTACTTGGATTAGATGAAA
CATGTAAAAAATTACTTGAT

Product: cobalt-precorrin-6Y C(5)-methyltransferase

Products: S-adenosyl-L-homocysteine; Precorrin 8X; CO2

Alternate protein names: Cobalt-precorrin-6 methyltransferase; Cobalt-precorrin-6Y methylase [H]

Number of amino acids: Translated: 198; Mature: 198

Protein sequence:

>198_residues
MITIVGIGPGDTNLLINEARQALSSADTVYGSNRQLQEIANLTTATPILLPKKLADLTNIPHQDKNVVILASGDPLLYGI
GNWAIANFSEDIRVIPGISAIQMMFHKIKLPMNDCFITSSHGKTPNFDFLLQHEKVAMVTDTIIGPYEIAAEILKRNLNK
IIFIGENLSAKEERIHKLRPAEVAKKYDMNVVVIVDER

Sequences:

>Translated_198_residues
MITIVGIGPGDTNLLINEARQALSSADTVYGSNRQLQEIANLTTATPILLPKKLADLTNIPHQDKNVVILASGDPLLYGI
GNWAIANFSEDIRVIPGISAIQMMFHKIKLPMNDCFITSSHGKTPNFDFLLQHEKVAMVTDTIIGPYEIAAEILKRNLNK
IIFIGENLSAKEERIHKLRPAEVAKKYDMNVVVIVDER
>Mature_198_residues
MITIVGIGPGDTNLLINEARQALSSADTVYGSNRQLQEIANLTTATPILLPKKLADLTNIPHQDKNVVILASGDPLLYGI
GNWAIANFSEDIRVIPGISAIQMMFHKIKLPMNDCFITSSHGKTPNFDFLLQHEKVAMVTDTIIGPYEIAAEILKRNLNK
IIFIGENLSAKEERIHKLRPAEVAKKYDMNVVVIVDER

Specific function: Probably catalyzes the methylation of C-5 in cobalt- precorrin-6Y to form cobalt-precorrin-7W-a [H]

COG id: COG2241

COG function: function code H; Precorrin-6B methylase 1

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000878
- InterPro:   IPR014777
- InterPro:   IPR012818 [H]

Pfam domain/function: PF00590 TP_methylase [H]

EC number: 2.1.1.132

Molecular weight: Translated: 21929; Mature: 21929

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITIVGIGPGDTNLLINEARQALSSADTVYGSNRQLQEIANLTTATPILLPKKLADLTNI
CEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHHCC
PHQDKNVVILASGDPLLYGIGNWAIANFSEDIRVIPGISAIQMMFHKIKLPMNDCFITSS
CCCCCCEEEEECCCEEEEECCCEEEECCCCCEEECCCHHHHHHHHHHHCCCCCCEEEECC
HGKTPNFDFLLQHEKVAMVTDTIIGPYEIAAEILKRNLNKIIFIGENLSAKEERIHKLRP
CCCCCCEEEEEECCEEEEEHHHCCCHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHCCH
AEVAKKYDMNVVVIVDER
HHHHHHHCCEEEEEEECC
>Mature Secondary Structure
MITIVGIGPGDTNLLINEARQALSSADTVYGSNRQLQEIANLTTATPILLPKKLADLTNI
CEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHHCC
PHQDKNVVILASGDPLLYGIGNWAIANFSEDIRVIPGISAIQMMFHKIKLPMNDCFITSS
CCCCCCEEEEECCCEEEEECCCEEEECCCCCEEECCCHHHHHHHHHHHCCCCCCEEEECC
HGKTPNFDFLLQHEKVAMVTDTIIGPYEIAAEILKRNLNKIIFIGENLSAKEERIHKLRP
CCCCCCEEEEEECCEEEEEHHHCCCHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHCCH
AEVAKKYDMNVVVIVDER
HHHHHHHCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: S-adenosyl-L-methionine; Precorrin 6Y

Specific reaction: 2 S-adenosyl-L-methionine + precorrin-6Y = 2 S-adenosyl-L-homocysteine + precorrin-8X + CO2

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]