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The map label for this gene is frwC [H]

Identifier: 116872019

GI number: 116872019

Start: 635646

End: 636707

Strand: Direct

Name: frwC [H]

Synonym: lwe0599

Alternate gene names: 116872019

Gene position: 635646-636707 (Clockwise)

Preceding gene: 116872018

Following gene: 116872020

Centisome position: 22.59

GC content: 41.9

Gene sequence:

>1062_bases
ATGAGAACACTTAAGTTTTTGCAAAAGCATTTGATGACAGCCACTTCTTATATGATTCCATTTGTGGTAGCTGGAGGGAT
TTTATTTGCACTATCTGTTATGTTGAGCGGACAAGCCGCAGTACCTGACGCGGGGTGGTTAGCAAAATTAAACCAAATTG
GTGCAGCTGGTCTCGCCCTTTTTATTCCGATTCTTGGTGGTTACATAGCATTTAGTATGGCGGATAAGCCAGGTCTTGCA
CCTGGGATGATTGGCGCATATTTAGCAAACGAAATTGGTGCTGGATTTATCGGTGGGATTATCGCTGGTTTCTTAGCTGG
TTTTGTCGTAATTCAATTAAAGAAAATTAAATTAGCTCCATCTATGAGAACACTCGGATCAATTTTTATTTATCCATTAC
TTGGGACTTTAATTACAGGTGGAATTATCGTCTTCCTCATTGGAGAACCAATCTCAGGTTTTATGGACTGGATGACAAAT
GCACTAAATAGTTTATCTGGCGCTGCAAAAGTTCCACTAGGGGCACTTCTTGGTGCAATGATTTCGTTTGATATGGGTGG
CCCTGTAAATAAAGTAGCAGCGACATTTGCGCAAACTCAAGTGGACACACTCCCTTATTTAATGGGTGGGGTTGGAGTAG
CGATTTGTGTACCACCAATAGGACTTGGAGTAGCAACTCTTCTGTTTCCTAAAAAATTTACTCGTGTGGAAAAAGATTCT
GGAATTGCGGCACTTTTGATGGGAAGCGTTGGTATCACGGAAGGAGCCATTCCTTTTGCAACAGCTGATCCATTACGAGT
TATCCCTTCGATTATGGTTGGTTCGATTGTAGGTAACGTTTCGGCTTTCTTATTCGGTTGTTTAAACCATGCGCCTTGGG
GTGGATTAATCGTTTTACCTGTGGTCGATAACCGAATTGGCTATGTTGCTTCTATTGCGCTTGGAGCTGTTGTGACGGCA
ATTATGCTCCGGATTTTGAAGAAAGATGCCACAGAGCTTGACGAGGCACTGGAAGAAGGGCAAGACATCGATGATTTAGA
TATTAATTTTGAAGATATTTAG

Upstream 100 bases:

>100_bases
AAGATTATTAATGCATGAAGATTTCCGAATGAAATTAAGTGAGTTAGACGACACTGCAACAGTGGCACTATTAAACAAAA
GTGTGAAGGAGGATAACTAA

Downstream 100 bases:

>100_bases
AAAGGATGATAATAATGAAAATTGTAGCAGTAACTTCCTGCCCAAGCGGTGTGGCGCATACGTATATGTCGGCAGAATCA
CTTGAACTCTCCGCTAAAAA

Product: putative fructose-like permease EIIC subunit 2

Products: NA

Alternate protein names: PTS system fructose-like EIIC component 2 [H]

Number of amino acids: Translated: 353; Mature: 353

Protein sequence:

>353_residues
MRTLKFLQKHLMTATSYMIPFVVAGGILFALSVMLSGQAAVPDAGWLAKLNQIGAAGLALFIPILGGYIAFSMADKPGLA
PGMIGAYLANEIGAGFIGGIIAGFLAGFVVIQLKKIKLAPSMRTLGSIFIYPLLGTLITGGIIVFLIGEPISGFMDWMTN
ALNSLSGAAKVPLGALLGAMISFDMGGPVNKVAATFAQTQVDTLPYLMGGVGVAICVPPIGLGVATLLFPKKFTRVEKDS
GIAALLMGSVGITEGAIPFATADPLRVIPSIMVGSIVGNVSAFLFGCLNHAPWGGLIVLPVVDNRIGYVASIALGAVVTA
IMLRILKKDATELDEALEEGQDIDDLDINFEDI

Sequences:

>Translated_353_residues
MRTLKFLQKHLMTATSYMIPFVVAGGILFALSVMLSGQAAVPDAGWLAKLNQIGAAGLALFIPILGGYIAFSMADKPGLA
PGMIGAYLANEIGAGFIGGIIAGFLAGFVVIQLKKIKLAPSMRTLGSIFIYPLLGTLITGGIIVFLIGEPISGFMDWMTN
ALNSLSGAAKVPLGALLGAMISFDMGGPVNKVAATFAQTQVDTLPYLMGGVGVAICVPPIGLGVATLLFPKKFTRVEKDS
GIAALLMGSVGITEGAIPFATADPLRVIPSIMVGSIVGNVSAFLFGCLNHAPWGGLIVLPVVDNRIGYVASIALGAVVTA
IMLRILKKDATELDEALEEGQDIDDLDINFEDI
>Mature_353_residues
MRTLKFLQKHLMTATSYMIPFVVAGGILFALSVMLSGQAAVPDAGWLAKLNQIGAAGLALFIPILGGYIAFSMADKPGLA
PGMIGAYLANEIGAGFIGGIIAGFLAGFVVIQLKKIKLAPSMRTLGSIFIYPLLGTLITGGIIVFLIGEPISGFMDWMTN
ALNSLSGAAKVPLGALLGAMISFDMGGPVNKVAATFAQTQVDTLPYLMGGVGVAICVPPIGLGVATLLFPKKFTRVEKDS
GIAALLMGSVGITEGAIPFATADPLRVIPSIMVGSIVGNVSAFLFGCLNHAPWGGLIVLPVVDNRIGYVASIALGAVVTA
IMLRILKKDATELDEALEEGQDIDDLDINFEDI

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane [H]

COG id: COG1299

COG function: function code G; Phosphotransferase system, fructose-specific IIC component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-2 domain [H]

Homologues:

Organism=Escherichia coli, GI1790386, Length=336, Percent_Identity=51.1904761904762, Blast_Score=295, Evalue=2e-81,
Organism=Escherichia coli, GI1788492, Length=326, Percent_Identity=42.638036809816, Blast_Score=231, Evalue=4e-62,
Organism=Escherichia coli, GI1786951, Length=353, Percent_Identity=33.4277620396601, Blast_Score=177, Evalue=1e-45,
Organism=Escherichia coli, GI87082348, Length=303, Percent_Identity=35.6435643564356, Blast_Score=163, Evalue=2e-41,
Organism=Escherichia coli, GI1788729, Length=376, Percent_Identity=28.4574468085106, Blast_Score=120, Evalue=1e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013014
- InterPro:   IPR006327 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 36596; Mature: 36596

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: PS51104 PTS_EIIC_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTLKFLQKHLMTATSYMIPFVVAGGILFALSVMLSGQAAVPDAGWLAKLNQIGAAGLAL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHH
FIPILGGYIAFSMADKPGLAPGMIGAYLANEIGAGFIGGIIAGFLAGFVVIQLKKIKLAP
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCC
SMRTLGSIFIYPLLGTLITGGIIVFLIGEPISGFMDWMTNALNSLSGAAKVPLGALLGAM
CHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
ISFDMGGPVNKVAATFAQTQVDTLPYLMGGVGVAICVPPIGLGVATLLFPKKFTRVEKDS
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHHHHHHCCC
GIAALLMGSVGITEGAIPFATADPLRVIPSIMVGSIVGNVSAFLFGCLNHAPWGGLIVLP
CHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEE
VVDNRIGYVASIALGAVVTAIMLRILKKDATELDEALEEGQDIDDLDINFEDI
EECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure
MRTLKFLQKHLMTATSYMIPFVVAGGILFALSVMLSGQAAVPDAGWLAKLNQIGAAGLAL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHH
FIPILGGYIAFSMADKPGLAPGMIGAYLANEIGAGFIGGIIAGFLAGFVVIQLKKIKLAP
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCC
SMRTLGSIFIYPLLGTLITGGIIVFLIGEPISGFMDWMTNALNSLSGAAKVPLGALLGAM
CHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
ISFDMGGPVNKVAATFAQTQVDTLPYLMGGVGVAICVPPIGLGVATLLFPKKFTRVEKDS
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHHHHHHCCC
GIAALLMGSVGITEGAIPFATADPLRVIPSIMVGSIVGNVSAFLFGCLNHAPWGGLIVLP
CHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEE
VVDNRIGYVASIALGAVVTAIMLRILKKDATELDEALEEGQDIDDLDINFEDI
EECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503; 7773398 [H]