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The map label for this gene is gcvT3 [H]

Identifier: 116695891

GI number: 116695891

Start: 2206138

End: 2208633

Strand: Direct

Name: gcvT3 [H]

Synonym: H16_B1955

Alternate gene names: 116695891

Gene position: 2206138-2208633 (Clockwise)

Preceding gene: 116695890

Following gene: 116695892

Centisome position: 75.75

GC content: 67.11

Gene sequence:

>2496_bases
ATGTCCCCTGTCATCCCATCCCACTCCCGCGTCGTCATCATCGGCGGCGGCATCATCGGTTGCAGCGTCGCCTATCACCT
GACCAAGCTCGGCTGGAAGGATGTGGTCCTGCTGGAACAGGGACAACTGTCCTGCGGCACCACCTGGCACGCGGCCGGGC
TGGTCGGGCAACTGCGCTCGCAGGAAAGCATGACGAAACTGATCCGCTACTCCACCCAGCTGTACAGCGAACTGGAAGCG
GAAACGGGCCTCGGCACCGGCTGGAAGCAATGCGGCTCGCTGTCGGTCGCGCGCACCGCGGAACGCATGACGCAACTGCG
CCGCACCGCGGCGGTGGCGCGGGCCTATGGCGTGGATTGCGAGGTGATCTCGCCCGCCCAGGCCGGCGAACTATGGCCGG
TGATGCGCACTGACGACCTGCTTGGGGCGGTCTGGCTGCCGGGCGACGGCAAGGCCAACCCGACTGACCTGACCCAGGCG
CTGGCGCGCGGCGCGCGCAGCCGCGGTGCGGTCATCGCGCAGGATACGAAGATCACCGCGATCCATACCCGCGATGGCCG
CGCCACCGGCGTGAGCTGGCGCAACAAGGCCGGCGACGAAGGCCGCATCGAGGCGGAGATCGTCGTCAACTGCGCCGGCC
AGTGGGCGCGCCAGGTCGGGCAGATGTGCGGCGTGACCGTGCCGCTGCACTCGGCCGAGCACTATTACATCGTCACCGAG
CGCATTGCCGGCGTGCATCCTGACCTGCCGGTGATGCGCGACCCGGACGGCTTCATCTACTTCAAGGAAGAAGTGGGCGG
GCTGGTGATGGGCGGCTTCGAGCCCAATGCCAAGCCGTGGGGCATGCAGGGCATTCCTGAGCCGTTCGAGTTCCAGTTGC
TGCCTGATGACTGGGATCAGTTCGAGATCCTGATGGAGAACGCGCTGATCCGCGTTCCGGCACTGGAGTCGGCGCAGGTC
AAGCAGTTCTACAATGGGCCCGAGTCCTTCACGCCGGACAACAACTTCATCCTCGGCGAAGCGCCCGAGCTGCGCAATTT
CTACGTGGGCGCGGGCTTCAACTCAATGGGGATCGCGTCTGCCGGCGGCGCCGGCATGGCACTGGCGGAATGGATCGTCG
CGGGCGACCCGACCATGGACCTGTGGCCGGTCGATATCCGCCGCTTTGCCGGCTTCAACGGCAACCAAAGCTGGCTGCAC
GACCGCGTCAGGGAAACGCTGGGCCTGCACTACGCGATGCCCTGGCCCAACCGGGAACTGGATACGGCGCGGCCGTTCCG
GCGCTCGCCGCTCTATGCCCACCTGCACGCTGCCGGCGCCAATTTCGGCAGCAAGATGGGCTGGGAGCGGCCAAACTTCT
TCGCGCCTGCCGGACAATCGCCCGAGATCCGCTACTCGTTCGGGCAACAGAACTGGCTGCCGTGGAGCGGCGCGGAACAC
CGCGCCTGCCGCGAGGCGGTGGCGCTGTTCGACATGAGTTCGTTCTCCAAGTACATCGTCAAGGGTGCCGATGCCGAGGC
CGTGCTGCAATACGTGATGAGCAACGACGTGGCCGTGCCGCCGGGGCAGACCGTGTACACCGCCATGCTCAACGATCGCG
GCACCTATGAATCCGACCTGACCGTGACGCGGCTGGCGCACGACCAGTACCTGCTGGTGACCGGCTCGGCGCAGACCACG
CGCGACTTCAACTATATCGAGCGCCTGATTCCGGCCGACAAGCGCTGCGCGATTGTCGATGTCACCGGGCAGTACGCCGT
GCTGGCGGTGATGGGCCCGCGCTCGCGCGAGCTGCTGCAGAGCGTGTCGCGCACCGATTTTTCCAATCAGGCGTTCCCGT
TCGGCACCTCGAAAGAGATCGATCTCGGCTATGCCACGGTGCGCGCCACACGCCTGACCTATGTGGGCGAACTGGGCTGG
GAGCTGTATGTCCCGGTGGAATTCGCCGTGGGCGTCCATGACACTTTGCACGAGGCCGGGAAACGCTTCGGACTGGTCAA
CGCCGGCTACTACGCCATCGAATCGCTGCGTATAGAGAAGGGCTACCGCGCCTGGAGCCGCGAACTGACCACCGACATCC
ATCCGTTCGAGGCCGGGCTGTCGTTTGCCTGCAAGCTGAACACGGACATCCCGTTCCGCGGGCGCGAAGCGCTGCTCAAG
CTGCGCGCTGCCGGCGGTGCCGCGCAGGTGCGGCGGCGCGTTGCCGTGGTCACGCTGGACGGCGCCAGCGAGGCCATGCT
CTGGGGCGGCGAGGCGATCCTGCGCACCGCCCCGGACGGCACCGTGCGCCCGGCCGGCTTCGTCACGTCGGCCGCGTTCG
GCCACACCCTTGGCTGTCCAGTGGGCATGGGCTTGCTGGCACGCGCCGATGGTCCGGCCGACGCGGCATGGATCGAGGGC
GGCAAGTATCACGTAGACCTGGCCGGGGAACTGCTGCCCGCGCGCATCCACCTGCGCGCGCCGTACGATCCGGCCAGCGA
GCGGACCAAGGCCTGA

Upstream 100 bases:

>100_bases
TGATCCGTCGACGTATGTTGCATTTTGTGTTGTTTGTTGGCGTTTTTTTGCATAACATGGCAGGCAACGCCAAACCCTTT
CCTGCCGAGGTTTTCCCGCC

Downstream 100 bases:

>100_bases
ACCTCGATGCAAGCGGATACCGGAGTGCCCATGCCAGTGATCCAGACCGAAACCGCCAGCTACATCCTGACGCTGTCATG
CCCCGACCGTCCCGGCATTG

Product: glycine cleavage system T protein

Products: NA

Alternate protein names: Glycine cleavage system T protein [H]

Number of amino acids: Translated: 831; Mature: 830

Protein sequence:

>831_residues
MSPVIPSHSRVVIIGGGIIGCSVAYHLTKLGWKDVVLLEQGQLSCGTTWHAAGLVGQLRSQESMTKLIRYSTQLYSELEA
ETGLGTGWKQCGSLSVARTAERMTQLRRTAAVARAYGVDCEVISPAQAGELWPVMRTDDLLGAVWLPGDGKANPTDLTQA
LARGARSRGAVIAQDTKITAIHTRDGRATGVSWRNKAGDEGRIEAEIVVNCAGQWARQVGQMCGVTVPLHSAEHYYIVTE
RIAGVHPDLPVMRDPDGFIYFKEEVGGLVMGGFEPNAKPWGMQGIPEPFEFQLLPDDWDQFEILMENALIRVPALESAQV
KQFYNGPESFTPDNNFILGEAPELRNFYVGAGFNSMGIASAGGAGMALAEWIVAGDPTMDLWPVDIRRFAGFNGNQSWLH
DRVRETLGLHYAMPWPNRELDTARPFRRSPLYAHLHAAGANFGSKMGWERPNFFAPAGQSPEIRYSFGQQNWLPWSGAEH
RACREAVALFDMSSFSKYIVKGADAEAVLQYVMSNDVAVPPGQTVYTAMLNDRGTYESDLTVTRLAHDQYLLVTGSAQTT
RDFNYIERLIPADKRCAIVDVTGQYAVLAVMGPRSRELLQSVSRTDFSNQAFPFGTSKEIDLGYATVRATRLTYVGELGW
ELYVPVEFAVGVHDTLHEAGKRFGLVNAGYYAIESLRIEKGYRAWSRELTTDIHPFEAGLSFACKLNTDIPFRGREALLK
LRAAGGAAQVRRRVAVVTLDGASEAMLWGGEAILRTAPDGTVRPAGFVTSAAFGHTLGCPVGMGLLARADGPADAAWIEG
GKYHVDLAGELLPARIHLRAPYDPASERTKA

Sequences:

>Translated_831_residues
MSPVIPSHSRVVIIGGGIIGCSVAYHLTKLGWKDVVLLEQGQLSCGTTWHAAGLVGQLRSQESMTKLIRYSTQLYSELEA
ETGLGTGWKQCGSLSVARTAERMTQLRRTAAVARAYGVDCEVISPAQAGELWPVMRTDDLLGAVWLPGDGKANPTDLTQA
LARGARSRGAVIAQDTKITAIHTRDGRATGVSWRNKAGDEGRIEAEIVVNCAGQWARQVGQMCGVTVPLHSAEHYYIVTE
RIAGVHPDLPVMRDPDGFIYFKEEVGGLVMGGFEPNAKPWGMQGIPEPFEFQLLPDDWDQFEILMENALIRVPALESAQV
KQFYNGPESFTPDNNFILGEAPELRNFYVGAGFNSMGIASAGGAGMALAEWIVAGDPTMDLWPVDIRRFAGFNGNQSWLH
DRVRETLGLHYAMPWPNRELDTARPFRRSPLYAHLHAAGANFGSKMGWERPNFFAPAGQSPEIRYSFGQQNWLPWSGAEH
RACREAVALFDMSSFSKYIVKGADAEAVLQYVMSNDVAVPPGQTVYTAMLNDRGTYESDLTVTRLAHDQYLLVTGSAQTT
RDFNYIERLIPADKRCAIVDVTGQYAVLAVMGPRSRELLQSVSRTDFSNQAFPFGTSKEIDLGYATVRATRLTYVGELGW
ELYVPVEFAVGVHDTLHEAGKRFGLVNAGYYAIESLRIEKGYRAWSRELTTDIHPFEAGLSFACKLNTDIPFRGREALLK
LRAAGGAAQVRRRVAVVTLDGASEAMLWGGEAILRTAPDGTVRPAGFVTSAAFGHTLGCPVGMGLLARADGPADAAWIEG
GKYHVDLAGELLPARIHLRAPYDPASERTKA
>Mature_830_residues
SPVIPSHSRVVIIGGGIIGCSVAYHLTKLGWKDVVLLEQGQLSCGTTWHAAGLVGQLRSQESMTKLIRYSTQLYSELEAE
TGLGTGWKQCGSLSVARTAERMTQLRRTAAVARAYGVDCEVISPAQAGELWPVMRTDDLLGAVWLPGDGKANPTDLTQAL
ARGARSRGAVIAQDTKITAIHTRDGRATGVSWRNKAGDEGRIEAEIVVNCAGQWARQVGQMCGVTVPLHSAEHYYIVTER
IAGVHPDLPVMRDPDGFIYFKEEVGGLVMGGFEPNAKPWGMQGIPEPFEFQLLPDDWDQFEILMENALIRVPALESAQVK
QFYNGPESFTPDNNFILGEAPELRNFYVGAGFNSMGIASAGGAGMALAEWIVAGDPTMDLWPVDIRRFAGFNGNQSWLHD
RVRETLGLHYAMPWPNRELDTARPFRRSPLYAHLHAAGANFGSKMGWERPNFFAPAGQSPEIRYSFGQQNWLPWSGAEHR
ACREAVALFDMSSFSKYIVKGADAEAVLQYVMSNDVAVPPGQTVYTAMLNDRGTYESDLTVTRLAHDQYLLVTGSAQTTR
DFNYIERLIPADKRCAIVDVTGQYAVLAVMGPRSRELLQSVSRTDFSNQAFPFGTSKEIDLGYATVRATRLTYVGELGWE
LYVPVEFAVGVHDTLHEAGKRFGLVNAGYYAIESLRIEKGYRAWSRELTTDIHPFEAGLSFACKLNTDIPFRGREALLKL
RAAGGAAQVRRRVAVVTLDGASEAMLWGGEAILRTAPDGTVRPAGFVTSAAFGHTLGCPVGMGLLARADGPADAAWIEGG
KYHVDLAGELLPARIHLRAPYDPASERTKA

Specific function: The glycine cleavage system catalyzes the degradation of glycine [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gcvT family [H]

Homologues:

Organism=Homo sapiens, GI197927446, Length=872, Percent_Identity=39.7935779816514, Blast_Score=603, Evalue=1e-172,
Organism=Homo sapiens, GI21361378, Length=872, Percent_Identity=39.7935779816514, Blast_Score=603, Evalue=1e-172,
Organism=Homo sapiens, GI194306651, Length=835, Percent_Identity=36.6467065868263, Blast_Score=551, Evalue=1e-156,
Organism=Homo sapiens, GI24797151, Length=819, Percent_Identity=34.1880341880342, Blast_Score=455, Evalue=1e-128,
Organism=Homo sapiens, GI8923708, Length=423, Percent_Identity=26.241134751773, Blast_Score=85, Evalue=3e-16,
Organism=Homo sapiens, GI257796258, Length=294, Percent_Identity=26.1904761904762, Blast_Score=78, Evalue=4e-14,
Organism=Homo sapiens, GI44662838, Length=294, Percent_Identity=26.1904761904762, Blast_Score=77, Evalue=9e-14,
Organism=Escherichia coli, GI1789272, Length=364, Percent_Identity=26.9230769230769, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI1787438, Length=441, Percent_Identity=21.7687074829932, Blast_Score=70, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI32563613, Length=847, Percent_Identity=32.5855962219599, Blast_Score=390, Evalue=1e-108,
Organism=Caenorhabditis elegans, GI71994045, Length=819, Percent_Identity=28.6935286935287, Blast_Score=300, Evalue=2e-81,
Organism=Caenorhabditis elegans, GI71994052, Length=826, Percent_Identity=28.4503631961259, Blast_Score=297, Evalue=1e-80,
Organism=Caenorhabditis elegans, GI17541536, Length=440, Percent_Identity=24.5454545454545, Blast_Score=91, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17560118, Length=354, Percent_Identity=24.5762711864407, Blast_Score=75, Evalue=2e-13,
Organism=Drosophila melanogaster, GI28571104, Length=848, Percent_Identity=38.6792452830189, Blast_Score=565, Evalue=1e-161,
Organism=Drosophila melanogaster, GI20130091, Length=878, Percent_Identity=33.8268792710706, Blast_Score=474, Evalue=1e-134,
Organism=Drosophila melanogaster, GI20129441, Length=330, Percent_Identity=26.6666666666667, Blast_Score=74, Evalue=5e-13,
Organism=Drosophila melanogaster, GI20129729, Length=438, Percent_Identity=25.5707762557078, Blast_Score=73, Evalue=7e-13,

Paralogues:

None

Copy number: 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013977
- InterPro:   IPR006222
- InterPro:   IPR006223
- InterPro:   IPR022903 [H]

Pfam domain/function: PF01571 GCV_T; PF08669 GCV_T_C [H]

EC number: =2.1.2.10 [H]

Molecular weight: Translated: 90819; Mature: 90688

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPVIPSHSRVVIIGGGIIGCSVAYHLTKLGWKDVVLLEQGQLSCGTTWHAAGLVGQLRS
CCCCCCCCCEEEEEECCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHHHH
QESMTKLIRYSTQLYSELEAETGLGTGWKQCGSLSVARTAERMTQLRRTAAVARAYGVDC
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
EVISPAQAGELWPVMRTDDLLGAVWLPGDGKANPTDLTQALARGARSRGAVIAQDTKITA
EEECCCCCCCCCCEEECCCCEEEEEECCCCCCCHHHHHHHHHHCCCCCCCEEEECCEEEE
IHTRDGRATGVSWRNKAGDEGRIEAEIVVNCAGQWARQVGQMCGVTVPLHSAEHYYIVTE
EECCCCCCCCCCCCCCCCCCCCEEEEEEEECHHHHHHHHHHHHCEEEEECCCCEEEEEEE
RIAGVHPDLPVMRDPDGFIYFKEEVGGLVMGGFEPNAKPWGMQGIPEPFEFQLLPDDWDQ
HHCCCCCCCCCEECCCCEEEEHHCCCCEEEECCCCCCCCCCCCCCCCCCEEEECCCCHHH
FEILMENALIRVPALESAQVKQFYNGPESFTPDNNFILGEAPELRNFYVGAGFNSMGIAS
HHHHHHCCEEECCCCCHHHHHHHHCCCCCCCCCCCEEECCCCCCCEEEEECCCCCCCCCC
AGGAGMALAEWIVAGDPTMDLWPVDIRRFAGFNGNQSWLHDRVRETLGLHYAMPWPNREL
CCCCCHHHHHHEECCCCCCCEEHHHHHHHCCCCCCHHHHHHHHHHHHCCEEECCCCCCCC
DTARPFRRSPLYAHLHAAGANFGSKMGWERPNFFAPAGQSPEIRYSFGQQNWLPWSGAEH
CCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCHH
RACREAVALFDMSSFSKYIVKGADAEAVLQYVMSNDVAVPPGQTVYTAMLNDRGTYESDL
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCCCCC
TVTRLAHDQYLLVTGSAQTTRDFNYIERLIPADKRCAIVDVTGQYAVLAVMGPRSRELLQ
EEEEECCCCEEEEECCCCCCHHHHHHHHHCCCCCCEEEEEECCCEEEEEEECCCHHHHHH
SVSRTDFSNQAFPFGTSKEIDLGYATVRATRLTYVGELGWELYVPVEFAVGVHDTLHEAG
HHHHCCCCCCCCCCCCCCCCCCCCEEEEEEHEEEEECCCCEEEEEEEEECCCHHHHHHHH
KRFGLVNAGYYAIESLRIEKGYRAWSRELTTDIHPFEAGLSFACKLNTDIPFRGREALLK
HHCCCEECCHHEEEEEEECCCHHHHHHHHCCCCCCHHCCCEEEEEECCCCCCCCHHHHHH
LRAAGGAAQVRRRVAVVTLDGASEAMLWGGEAILRTAPDGTVRPAGFVTSAAFGHTLGCP
HHCCCCHHHHCCEEEEEEECCCCCEEEECCCEEEEECCCCCCCCCCHHHHHHCCCCCCCC
VGMGLLARADGPADAAWIEGGKYHVDLAGELLPARIHLRAPYDPASERTKA
CCCCEEEECCCCCCHHEECCCEEEEEECCCCCEEEEEEECCCCCCCCCCCC
>Mature Secondary Structure 
SPVIPSHSRVVIIGGGIIGCSVAYHLTKLGWKDVVLLEQGQLSCGTTWHAAGLVGQLRS
CCCCCCCCEEEEEECCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHHHH
QESMTKLIRYSTQLYSELEAETGLGTGWKQCGSLSVARTAERMTQLRRTAAVARAYGVDC
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
EVISPAQAGELWPVMRTDDLLGAVWLPGDGKANPTDLTQALARGARSRGAVIAQDTKITA
EEECCCCCCCCCCEEECCCCEEEEEECCCCCCCHHHHHHHHHHCCCCCCCEEEECCEEEE
IHTRDGRATGVSWRNKAGDEGRIEAEIVVNCAGQWARQVGQMCGVTVPLHSAEHYYIVTE
EECCCCCCCCCCCCCCCCCCCCEEEEEEEECHHHHHHHHHHHHCEEEEECCCCEEEEEEE
RIAGVHPDLPVMRDPDGFIYFKEEVGGLVMGGFEPNAKPWGMQGIPEPFEFQLLPDDWDQ
HHCCCCCCCCCEECCCCEEEEHHCCCCEEEECCCCCCCCCCCCCCCCCCEEEECCCCHHH
FEILMENALIRVPALESAQVKQFYNGPESFTPDNNFILGEAPELRNFYVGAGFNSMGIAS
HHHHHHCCEEECCCCCHHHHHHHHCCCCCCCCCCCEEECCCCCCCEEEEECCCCCCCCCC
AGGAGMALAEWIVAGDPTMDLWPVDIRRFAGFNGNQSWLHDRVRETLGLHYAMPWPNREL
CCCCCHHHHHHEECCCCCCCEEHHHHHHHCCCCCCHHHHHHHHHHHHCCEEECCCCCCCC
DTARPFRRSPLYAHLHAAGANFGSKMGWERPNFFAPAGQSPEIRYSFGQQNWLPWSGAEH
CCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCHH
RACREAVALFDMSSFSKYIVKGADAEAVLQYVMSNDVAVPPGQTVYTAMLNDRGTYESDL
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCCCCC
TVTRLAHDQYLLVTGSAQTTRDFNYIERLIPADKRCAIVDVTGQYAVLAVMGPRSRELLQ
EEEEECCCCEEEEECCCCCCHHHHHHHHHCCCCCCEEEEEECCCEEEEEEECCCHHHHHH
SVSRTDFSNQAFPFGTSKEIDLGYATVRATRLTYVGELGWELYVPVEFAVGVHDTLHEAG
HHHHCCCCCCCCCCCCCCCCCCCCEEEEEEHEEEEECCCCEEEEEEEEECCCHHHHHHHH
KRFGLVNAGYYAIESLRIEKGYRAWSRELTTDIHPFEAGLSFACKLNTDIPFRGREALLK
HHCCCEECCHHEEEEEEECCCHHHHHHHHCCCCCCHHCCCEEEEEECCCCCCCCHHHHHH
LRAAGGAAQVRRRVAVVTLDGASEAMLWGGEAILRTAPDGTVRPAGFVTSAAFGHTLGCP
HHCCCCHHHHCCEEEEEEECCCCCEEEECCCEEEEECCCCCCCCCCHHHHHHCCCCCCCC
VGMGLLARADGPADAAWIEGGKYHVDLAGELLPARIHLRAPYDPASERTKA
CCCCEEEECCCCCCHHEECCCEEEEEECCCCCEEEEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA