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The map label for this gene is kguK [H]

Identifier: 116695748

GI number: 116695748

Start: 2048486

End: 2049430

Strand: Direct

Name: kguK [H]

Synonym: H16_B1812

Alternate gene names: 116695748

Gene position: 2048486-2049430 (Clockwise)

Preceding gene: 116695747

Following gene: 116695749

Centisome position: 70.33

GC content: 71.43

Gene sequence:

>945_bases
ATGAGCACCGATCTTGACGTGGTCACGCTGGGCGAGGCGATGCTGATGCTGGTCGCCGGCGAAGCCGGGCCGCTCGAAGG
CGCGCAGACCTTCCACAAGCGCACCGCCGGTGCCGAGACCAATGTGGCCATCGGCCTGTCGCGCCTGGGCCTGAAGGTTG
GCTGGGCCAGCCGGCTGGGCGACGACTCGATGGCCCGCTACCTGCTCGGCGAAATGCAGCGCGAAGGCGTGGATTGCAGC
CAGGTGGTGTGCGAGCCCGGTGAGCGCACCGGTTTCCAGTTCAAGGGCCGGGTCGACGACGGCAGCGATCCCCCCGTCGA
ATACCACCGCCGCGGCTCGGCGGCGAGCCGCATGAACCCGGAGCACCTGGACGGCAGGTGGCTGCGGCGCTCGCGGCACC
TGCACGTCACCGGCGTGTTCCCCGCGCTGGCCGCAGGCACGCAGGCCGCCACGCGCCAGGCCATCGCCACCATGCAGGCC
GCCGGCCGCACGATCTCATTCGATCCCAACCTGCGGCCCACGCTGTGGGCCTCGCCCGAGTTGATGCGGGAGACGCTGAA
CGACCTGGCGCAGCAGTGCGACTGGGTGCTGCCCGGCATCGAAGAGGGCCGCTTCCTCACCGGCCACGCCGAGCCGGAAC
GCATTGCCGCCTTCTACCGTGCCCGCGGCGCCAGGCTGGTGGTGGTGAAGCTGGGCGCCGACGGCGCCTACTTCGATGGC
GAGGCCGGCACCGGCCATGTCGAGGCATTCAGCGTCGAGCATGTTGTCGATACCGTTGGCGCCGGCGATGGCTTTGCCGT
CGGCGTGATCAGCGCGCTGCTGGAGGGCCGGCCAGTGCGCGACGCCGTCCGGCGCGGCGCCTGGATCGGCGCCCGCGCGG
TGCAGGTGCGCGGCGATACCGAAGGCCTGCCGACCCATGCCCAGCTGGCGGCCGCCAGTTTGTGA

Upstream 100 bases:

>100_bases
CGCACGTTGCGCGTGCGATCGAATTCCCGCTGCAAGGCGAAGACCTGGTGCAGGTCACGCGCCATCATGTCGAACTGCTG
CGTTCGGTGGAGGTCCCCGC

Downstream 100 bases:

>100_bases
AGCCACTGCAAGGATTACCCATGCGCAAGAATGTCCTGGTGTTCCGCCCGATTCCTGATGACCTGCTCGCCAGGATCGAA
TCGGAGCACGATGTGATCGT

Product: putative 2-ketogluconate kinase

Products: NA

Alternate protein names: 2-keto-3-deoxygluconokinase; 3-deoxy-2-oxo-D-gluconate kinase; KDG kinase [H]

Number of amino acids: Translated: 314; Mature: 313

Protein sequence:

>314_residues
MSTDLDVVTLGEAMLMLVAGEAGPLEGAQTFHKRTAGAETNVAIGLSRLGLKVGWASRLGDDSMARYLLGEMQREGVDCS
QVVCEPGERTGFQFKGRVDDGSDPPVEYHRRGSAASRMNPEHLDGRWLRRSRHLHVTGVFPALAAGTQAATRQAIATMQA
AGRTISFDPNLRPTLWASPELMRETLNDLAQQCDWVLPGIEEGRFLTGHAEPERIAAFYRARGARLVVVKLGADGAYFDG
EAGTGHVEAFSVEHVVDTVGAGDGFAVGVISALLEGRPVRDAVRRGAWIGARAVQVRGDTEGLPTHAQLAAASL

Sequences:

>Translated_314_residues
MSTDLDVVTLGEAMLMLVAGEAGPLEGAQTFHKRTAGAETNVAIGLSRLGLKVGWASRLGDDSMARYLLGEMQREGVDCS
QVVCEPGERTGFQFKGRVDDGSDPPVEYHRRGSAASRMNPEHLDGRWLRRSRHLHVTGVFPALAAGTQAATRQAIATMQA
AGRTISFDPNLRPTLWASPELMRETLNDLAQQCDWVLPGIEEGRFLTGHAEPERIAAFYRARGARLVVVKLGADGAYFDG
EAGTGHVEAFSVEHVVDTVGAGDGFAVGVISALLEGRPVRDAVRRGAWIGARAVQVRGDTEGLPTHAQLAAASL
>Mature_313_residues
STDLDVVTLGEAMLMLVAGEAGPLEGAQTFHKRTAGAETNVAIGLSRLGLKVGWASRLGDDSMARYLLGEMQREGVDCSQ
VVCEPGERTGFQFKGRVDDGSDPPVEYHRRGSAASRMNPEHLDGRWLRRSRHLHVTGVFPALAAGTQAATRQAIATMQAA
GRTISFDPNLRPTLWASPELMRETLNDLAQQCDWVLPGIEEGRFLTGHAEPERIAAFYRARGARLVVVKLGADGAYFDGE
AGTGHVEAFSVEHVVDTVGAGDGFAVGVISALLEGRPVRDAVRRGAWIGARAVQVRGDTEGLPTHAQLAAASL

Specific function: Unknown

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Escherichia coli, GI87081971, Length=334, Percent_Identity=28.7425149700599, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI87082281, Length=304, Percent_Identity=26.6447368421053, Blast_Score=83, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.45 [H]

Molecular weight: Translated: 33563; Mature: 33432

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTDLDVVTLGEAMLMLVAGEAGPLEGAQTFHKRTAGAETNVAIGLSRLGLKVGWASRLG
CCCCCCEEEHHHHEEEEEECCCCCCCHHHHHHHHHCCCCCCCEEEHHHHCEEECHHHHCC
DDSMARYLLGEMQREGVDCSQVVCEPGERTGFQFKGRVDDGSDPPVEYHRRGSAASRMNP
CHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCEEEEECCCCCCCCCHHHHHCCCHHHCCCH
EHLDGRWLRRSRHLHVTGVFPALAAGTQAATRQAIATMQAAGRTISFDPNLRPTLWASPE
HHCCCHHHHHCCCEEEEECHHHHHCCCHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCHH
LMRETLNDLAQQCDWVLPGIEEGRFLTGHAEPERIAAFYRARGARLVVVKLGADGAYFDG
HHHHHHHHHHHHCCEECCCCCCCCEEECCCCHHHHHHHHHCCCCEEEEEEECCCCCEECC
EAGTGHVEAFSVEHVVDTVGAGDGFAVGVISALLEGRPVRDAVRRGAWIGARAVQVRGDT
CCCCCCEEEEEHHHHHHHCCCCCCHHHHHHHHHHCCCCHHHHHHCCCEECCEEEEEECCC
EGLPTHAQLAAASL
CCCCCHHHHHHHCC
>Mature Secondary Structure 
STDLDVVTLGEAMLMLVAGEAGPLEGAQTFHKRTAGAETNVAIGLSRLGLKVGWASRLG
CCCCCEEEHHHHEEEEEECCCCCCCHHHHHHHHHCCCCCCCEEEHHHHCEEECHHHHCC
DDSMARYLLGEMQREGVDCSQVVCEPGERTGFQFKGRVDDGSDPPVEYHRRGSAASRMNP
CHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCEEEEECCCCCCCCCHHHHHCCCHHHCCCH
EHLDGRWLRRSRHLHVTGVFPALAAGTQAATRQAIATMQAAGRTISFDPNLRPTLWASPE
HHCCCHHHHHCCCEEEEECHHHHHCCCHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCHH
LMRETLNDLAQQCDWVLPGIEEGRFLTGHAEPERIAAFYRARGARLVVVKLGADGAYFDG
HHHHHHHHHHHHCCEECCCCCCCCEEECCCCHHHHHHHHHCCCCEEEEEEECCCCCEECC
EAGTGHVEAFSVEHVVDTVGAGDGFAVGVISALLEGRPVRDAVRRGAWIGARAVQVRGDT
CCCCCCEEEEEHHHHHHHCCCCCCHHHHHHHHHHCCCCHHHHHHCCCEECCEEEEEECCC
EGLPTHAQLAAASL
CCCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8760912; 9384377 [H]