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The map label for this gene is yfdE [H]

Identifier: 116695685

GI number: 116695685

Start: 1987038

End: 1988174

Strand: Direct

Name: yfdE [H]

Synonym: H16_B1749

Alternate gene names: 116695685

Gene position: 1987038-1988174 (Clockwise)

Preceding gene: 116695684

Following gene: 116695686

Centisome position: 68.22

GC content: 66.93

Gene sequence:

>1137_bases
ATGAGCGGTCCATTGAAAGGCGTCAGGATCATCGAGTTCGGCGCAATCGGGCCGGCGCCATTCGCCTGCATGATGCTGGC
CGACAACGGCGCGGACGTCATCCGCGTGGCGCGGCATGTACCGGCCTGGCGGCAAGGCATCATGGATGCGAGCAAGGACG
TTCTGGCACGCTCGCGCCGCGTCGTGCACCTTGACCTCAAGACGCCCGAAGGTGTGCGCGAGGCCCGCGCGCTCGCACGC
GACGCGGACGGCATTGTCGAGGGCTACCGCCCGGGCGTCATGGAAAGACTCGGGCTTGGCCCTGAGGTCTTGCTGGCTGA
CAACCCGCGGCTGGTGTACGGGCGCATGACCGGATGGGGCCAGGACGGGCCCCTCGCACAGCGCGCCGGGCACGACATCA
ACTACATCGCGCTGGCCGGTGCATTGCACGCCTTCGGGCGCGAGGGCGGCAAGCCAACGCCACCCGCCAACCTGGTCGCA
GACTTTGGCGGCGGCGGCATGTTGCTTGCGTTCGGCATGGTCAGCGCCATCCTGCATGCACGCGCCACGGGGGAAGGTCA
GGTGGTGGACTGCGCCATGCTCGACGGCACCGCGTTGCTGATGAGCATGATGTGGTCGCTGCGTTCCGCCGGTGTGTGGC
GCGACGAGCGCGGTGTCAATCTGCTCGACACCGGCACGCATTTCTACGAGACGTATGAGACCAGCGATGGCAAGTACATC
GCGATCGGCGCGGTTGAGCCCGAGTTCTATGCGCTGCTGCGGGAAAGGCTAGGTCTGGCCGACGACCCGGACTTCGACCG
CCAGCGGGACCCGAAAGCCTGGCCGGATCTCAAAGCCAGGCTTTCCACGATCTTCAAGACCCGCAGCCGCGACGAATGGT
GCCGCATCTTCGACCCCACCGATGCCTGTGTCACCCCGGTCCTTTCGATGAGCGAGGCGCCCGATCACCCGCACGCCCGC
GCGCGCGGGGTATTCACGACCATCGATGGTGTCGTGCAGCCCAGCCCGGCTCCGCGCTACTCGCGCACCGTGAACGATGC
ACCCAGGATGCTTCGCCCTCAACAGGACGATCGCGATGCGATCCGCCCCGGGCGTCGCACCGCACTGTGCGCAAGCGAAC
CGGCAACCGATAGCTGA

Upstream 100 bases:

>100_bases
AGACGGCAACGCAGATCAACCAGGCCTTTGCAAGCCGGGTGGTCGCCGGCCGCATGGACGAGGCGGATGCCGCAGGCAAG
TCCGCGGTGGGAGCACAAGC

Downstream 100 bases:

>100_bases
GGGGTAAGCGAAATGAGCAGAATTGCATTCATTGGTCTTGGCAATATGGGCATGCCCATGGCCCTGAACCTTGTACGTGC
GGGCCACGACGTGCAGGGAT

Product: acyl-CoA transferase/carnitine dehydratase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 378; Mature: 377

Protein sequence:

>378_residues
MSGPLKGVRIIEFGAIGPAPFACMMLADNGADVIRVARHVPAWRQGIMDASKDVLARSRRVVHLDLKTPEGVREARALAR
DADGIVEGYRPGVMERLGLGPEVLLADNPRLVYGRMTGWGQDGPLAQRAGHDINYIALAGALHAFGREGGKPTPPANLVA
DFGGGGMLLAFGMVSAILHARATGEGQVVDCAMLDGTALLMSMMWSLRSAGVWRDERGVNLLDTGTHFYETYETSDGKYI
AIGAVEPEFYALLRERLGLADDPDFDRQRDPKAWPDLKARLSTIFKTRSRDEWCRIFDPTDACVTPVLSMSEAPDHPHAR
ARGVFTTIDGVVQPSPAPRYSRTVNDAPRMLRPQQDDRDAIRPGRRTALCASEPATDS

Sequences:

>Translated_378_residues
MSGPLKGVRIIEFGAIGPAPFACMMLADNGADVIRVARHVPAWRQGIMDASKDVLARSRRVVHLDLKTPEGVREARALAR
DADGIVEGYRPGVMERLGLGPEVLLADNPRLVYGRMTGWGQDGPLAQRAGHDINYIALAGALHAFGREGGKPTPPANLVA
DFGGGGMLLAFGMVSAILHARATGEGQVVDCAMLDGTALLMSMMWSLRSAGVWRDERGVNLLDTGTHFYETYETSDGKYI
AIGAVEPEFYALLRERLGLADDPDFDRQRDPKAWPDLKARLSTIFKTRSRDEWCRIFDPTDACVTPVLSMSEAPDHPHAR
ARGVFTTIDGVVQPSPAPRYSRTVNDAPRMLRPQQDDRDAIRPGRRTALCASEPATDS
>Mature_377_residues
SGPLKGVRIIEFGAIGPAPFACMMLADNGADVIRVARHVPAWRQGIMDASKDVLARSRRVVHLDLKTPEGVREARALARD
ADGIVEGYRPGVMERLGLGPEVLLADNPRLVYGRMTGWGQDGPLAQRAGHDINYIALAGALHAFGREGGKPTPPANLVAD
FGGGGMLLAFGMVSAILHARATGEGQVVDCAMLDGTALLMSMMWSLRSAGVWRDERGVNLLDTGTHFYETYETSDGKYIA
IGAVEPEFYALLRERLGLADDPDFDRQRDPKAWPDLKARLSTIFKTRSRDEWCRIFDPTDACVTPVLSMSEAPDHPHARA
RGVFTTIDGVVQPSPAPRYSRTVNDAPRMLRPQQDDRDAIRPGRRTALCASEPATDS

Specific function: Unknown

COG id: COG1804

COG function: function code C; Predicted acyl-CoA transferases/carnitine dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CaiB/BaiF CoA-transferase family [H]

Homologues:

Organism=Homo sapiens, GI42794625, Length=335, Percent_Identity=45.6716417910448, Blast_Score=310, Evalue=1e-84,
Organism=Homo sapiens, GI266456254, Length=335, Percent_Identity=45.6716417910448, Blast_Score=310, Evalue=2e-84,
Organism=Homo sapiens, GI266458393, Length=254, Percent_Identity=46.8503937007874, Blast_Score=239, Evalue=3e-63,
Organism=Homo sapiens, GI266458397, Length=249, Percent_Identity=46.9879518072289, Blast_Score=237, Evalue=1e-62,
Organism=Homo sapiens, GI300863128, Length=362, Percent_Identity=28.1767955801105, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI300863124, Length=388, Percent_Identity=27.0618556701031, Blast_Score=133, Evalue=3e-31,
Organism=Homo sapiens, GI266458395, Length=136, Percent_Identity=47.0588235294118, Blast_Score=122, Evalue=4e-28,
Organism=Homo sapiens, GI42822893, Length=141, Percent_Identity=45.3900709219858, Blast_Score=122, Evalue=6e-28,
Organism=Homo sapiens, GI300863126, Length=356, Percent_Identity=25, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI13376042, Length=388, Percent_Identity=23.7113402061856, Blast_Score=97, Evalue=2e-20,
Organism=Escherichia coli, GI87082093, Length=345, Percent_Identity=26.3768115942029, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1788717, Length=214, Percent_Identity=30.3738317757009, Blast_Score=89, Evalue=6e-19,
Organism=Escherichia coli, GI1786222, Length=364, Percent_Identity=25.2747252747253, Blast_Score=65, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI115535051, Length=346, Percent_Identity=37.5722543352601, Blast_Score=227, Evalue=1e-59,
Organism=Caenorhabditis elegans, GI32564160, Length=340, Percent_Identity=37.3529411764706, Blast_Score=220, Evalue=1e-57,
Organism=Drosophila melanogaster, GI24585488, Length=347, Percent_Identity=42.3631123919308, Blast_Score=295, Evalue=4e-80,
Organism=Drosophila melanogaster, GI24648431, Length=365, Percent_Identity=30.4109589041096, Blast_Score=127, Evalue=9e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003673 [H]

Pfam domain/function: PF02515 CoA_transf_3 [H]

EC number: NA

Molecular weight: Translated: 41169; Mature: 41038

Theoretical pI: Translated: 6.72; Mature: 6.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGPLKGVRIIEFGAIGPAPFACMMLADNGADVIRVARHVPAWRQGIMDASKDVLARSRR
CCCCCCCEEEEEECCCCCCCEEEEEEECCCHHHHHHHHHCCHHHHHHHHHHHHHHHHCCC
VVHLDLKTPEGVREARALARDADGIVEGYRPGVMERLGLGPEVLLADNPRLVYGRMTGWG
EEEEECCCCCHHHHHHHHHHCCHHHHHCCCCCHHHHHCCCCEEEEECCCEEEEEECCCCC
QDGPLAQRAGHDINYIALAGALHAFGREGGKPTPPANLVADFGGGGMLLAFGMVSAILHA
CCCCHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHEEECCCCHHHHHHHHHHHHHHH
RATGEGQVVDCAMLDGTALLMSMMWSLRSAGVWRDERGVNLLDTGTHFYETYETSDGKYI
HCCCCCCEEEEEECCHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCEEEEEEECCCCCEE
AIGAVEPEFYALLRERLGLADDPDFDRQRDPKAWPDLKARLSTIFKTRSRDEWCRIFDPT
EEECCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEECCC
DACVTPVLSMSEAPDHPHARARGVFTTIDGVVQPSPAPRYSRTVNDAPRMLRPQQDDRDA
HHHHHHHHHHCCCCCCCCHHHCCEEEECCCCCCCCCCCCHHCCCCCCHHHCCCCCCCHHH
IRPGRRTALCASEPATDS
HCCCCCEEEECCCCCCCC
>Mature Secondary Structure 
SGPLKGVRIIEFGAIGPAPFACMMLADNGADVIRVARHVPAWRQGIMDASKDVLARSRR
CCCCCCEEEEEECCCCCCCEEEEEEECCCHHHHHHHHHCCHHHHHHHHHHHHHHHHCCC
VVHLDLKTPEGVREARALARDADGIVEGYRPGVMERLGLGPEVLLADNPRLVYGRMTGWG
EEEEECCCCCHHHHHHHHHHCCHHHHHCCCCCHHHHHCCCCEEEEECCCEEEEEECCCCC
QDGPLAQRAGHDINYIALAGALHAFGREGGKPTPPANLVADFGGGGMLLAFGMVSAILHA
CCCCHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHEEECCCCHHHHHHHHHHHHHHH
RATGEGQVVDCAMLDGTALLMSMMWSLRSAGVWRDERGVNLLDTGTHFYETYETSDGKYI
HCCCCCCEEEEEECCHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCEEEEEEECCCCCEE
AIGAVEPEFYALLRERLGLADDPDFDRQRDPKAWPDLKARLSTIFKTRSRDEWCRIFDPT
EEECCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEECCC
DACVTPVLSMSEAPDHPHARARGVFTTIDGVVQPSPAPRYSRTVNDAPRMLRPQQDDRDA
HHHHHHHHHHCCCCCCCCHHHCCEEEECCCCCCCCCCCCHHCCCCCCHHHCCCCCCCHHH
IRPGRRTALCASEPATDS
HCCCCCEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503; 8125343 [H]