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The map label for this gene is can [H]

Identifier: 116690945

GI number: 116690945

Start: 3236200

End: 3236967

Strand: Direct

Name: can [H]

Synonym: Bcen2424_2927

Alternate gene names: 116690945

Gene position: 3236200-3236967 (Clockwise)

Preceding gene: 116690944

Following gene: 116690946

Centisome position: 92.89

GC content: 66.15

Gene sequence:

>768_bases
ATGACTACCCAAGACAATCCGCTTTCACATCTGTTCGACAACAACGATGCCTGGGTCAAGCGCCAGCTCGCCGACGATCC
CGATTTCTTCGCACGGCTCGCCGACCAGCAGGCGCCGGAATATCTGTGGATCGGCTGCTCGGATTCGCGCGTGCCGGCGA
ACCAGATCATCGGCCTGCCGCCGGGTGAAGTGTTCGTGCACCGCAACATCGCGAACGTGGTCGTGCACAGCGACCTGAAC
TGCCTGTCGGTGATCCAGTTCGCGGTCGACATCCTGCGCGTGAAGCACATCATGGTCGTCGGCCACTACGGCTGCTCGGG
CGTGAACGCGGCGCTGCATAACCGCCGCGTCGGCCTCGCGGACAATTGGCTGCATCACGTGCAGGACGTGCGCGAGCGCC
ATGCGGCGCTGCTCGACGAATGGCCGGTCGGCGAAGCGCGTTACCGTCGCCTGATCGAGCTGAATTCGATCGAACAGGTC
GTCAACGTGTGCCGCACGACGATCGTCAACGACGCGTGGGCGCGCGGCCAGTCGCTGACCGTGCACGGGCTCGTGTACGG
CGTGCACGACGGCCGGATGCGCAACCTCGGGATGTCCGTGTCGAACTTCGATGCGCTCGACGCAACCTACAAGCGCTGCG
TGGCGGCGCTGACGGCACGCGGCCAGCATGCGCCCGACAACGACATGGTCGCGGCGGACGCCGCGCAGCTCGACGGCGTC
GCGCAGGCGGTCGCCGCCACGCTGAAGCCGTGCGACGACGCGCAGTAA

Upstream 100 bases:

>100_bases
GGGCGAGAACGACGGCGCAGGCGACGCGCAGCGCGCCGCCTGACGCCGGCCACACCCCGATCCGATATCGACTTGATTTC
CGCCAACGGAATCCACACCG

Downstream 100 bases:

>100_bases
CGTGCGGTGACGCGCTAGCTGCCCGGCGGCGGCTGCCGCGCGGGCGCGGCACGCGTCGAACGGATCTGACACCGGCACCG
CCACGGCGGCGCCAACCCAA

Product: carbonate dehydratase

Products: NA

Alternate protein names: Carbonate dehydratase 2 [H]

Number of amino acids: Translated: 255; Mature: 254

Protein sequence:

>255_residues
MTTQDNPLSHLFDNNDAWVKRQLADDPDFFARLADQQAPEYLWIGCSDSRVPANQIIGLPPGEVFVHRNIANVVVHSDLN
CLSVIQFAVDILRVKHIMVVGHYGCSGVNAALHNRRVGLADNWLHHVQDVRERHAALLDEWPVGEARYRRLIELNSIEQV
VNVCRTTIVNDAWARGQSLTVHGLVYGVHDGRMRNLGMSVSNFDALDATYKRCVAALTARGQHAPDNDMVAADAAQLDGV
AQAVAATLKPCDDAQ

Sequences:

>Translated_255_residues
MTTQDNPLSHLFDNNDAWVKRQLADDPDFFARLADQQAPEYLWIGCSDSRVPANQIIGLPPGEVFVHRNIANVVVHSDLN
CLSVIQFAVDILRVKHIMVVGHYGCSGVNAALHNRRVGLADNWLHHVQDVRERHAALLDEWPVGEARYRRLIELNSIEQV
VNVCRTTIVNDAWARGQSLTVHGLVYGVHDGRMRNLGMSVSNFDALDATYKRCVAALTARGQHAPDNDMVAADAAQLDGV
AQAVAATLKPCDDAQ
>Mature_254_residues
TTQDNPLSHLFDNNDAWVKRQLADDPDFFARLADQQAPEYLWIGCSDSRVPANQIIGLPPGEVFVHRNIANVVVHSDLNC
LSVIQFAVDILRVKHIMVVGHYGCSGVNAALHNRRVGLADNWLHHVQDVRERHAALLDEWPVGEARYRRLIELNSIEQVV
NVCRTTIVNDAWARGQSLTVHGLVYGVHDGRMRNLGMSVSNFDALDATYKRCVAALTARGQHAPDNDMVAADAAQLDGVA
QAVAATLKPCDDAQ

Specific function: Unknown

COG id: COG0288

COG function: function code P; Carbonic anhydrase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-class carbonic anhydrase family [H]

Homologues:

Organism=Escherichia coli, GI1786318, Length=210, Percent_Identity=50.9523809523809, Blast_Score=241, Evalue=5e-65,
Organism=Escherichia coli, GI1786534, Length=212, Percent_Identity=27.3584905660377, Blast_Score=70, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6324292, Length=191, Percent_Identity=28.7958115183246, Blast_Score=86, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001765
- InterPro:   IPR015892 [H]

Pfam domain/function: PF00484 Pro_CA [H]

EC number: =4.2.1.1 [H]

Molecular weight: Translated: 28157; Mature: 28026

Theoretical pI: Translated: 6.22; Mature: 6.22

Prosite motif: PS00704 PROK_CO2_ANHYDRASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTQDNPLSHLFDNNDAWVKRQLADDPDFFARLADQQAPEYLWIGCSDSRVPANQIIGLP
CCCCCCCHHHHHCCCCHHHHHHHCCCHHHHHHHHHCCCCCEEEEECCCCCCCHHHEECCC
PGEVFVHRNIANVVVHSDLNCLSVIQFAVDILRVKHIMVVGHYGCSGVNAALHNRRVGLA
CCCEEEECCHHHEEEECCCHHHHHHHHHHHHHHHHHHEEEECCCCCCHHHHHHCCCCCCH
DNWLHHVQDVRERHAALLDEWPVGEARYRRLIELNSIEQVVNVCRTTIVNDAWARGQSLT
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
VHGLVYGVHDGRMRNLGMSVSNFDALDATYKRCVAALTARGQHAPDNDMVAADAAQLDGV
EEEEEEECCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEHHHHHHHHH
AQAVAATLKPCDDAQ
HHHHHHHHCCCCCCC
>Mature Secondary Structure 
TTQDNPLSHLFDNNDAWVKRQLADDPDFFARLADQQAPEYLWIGCSDSRVPANQIIGLP
CCCCCCHHHHHCCCCHHHHHHHCCCHHHHHHHHHCCCCCEEEEECCCCCCCHHHEECCC
PGEVFVHRNIANVVVHSDLNCLSVIQFAVDILRVKHIMVVGHYGCSGVNAALHNRRVGLA
CCCEEEECCHHHEEEECCCHHHHHHHHHHHHHHHHHHEEEECCCCCCHHHHHHCCCCCCH
DNWLHHVQDVRERHAALLDEWPVGEARYRRLIELNSIEQVVNVCRTTIVNDAWARGQSLT
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
VHGLVYGVHDGRMRNLGMSVSNFDALDATYKRCVAALTARGQHAPDNDMVAADAAQLDGV
EEEEEEECCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEHHHHHHHHH
AQAVAATLKPCDDAQ
HHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8202364; 9278503; 10493123 [H]