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The map label for this gene is csgA [H]

Identifier: 116690946

GI number: 116690946

Start: 3237080

End: 3237757

Strand: Direct

Name: csgA [H]

Synonym: Bcen2424_2928

Alternate gene names: 116690946

Gene position: 3237080-3237757 (Clockwise)

Preceding gene: 116690945

Following gene: 116690947

Centisome position: 92.92

GC content: 70.35

Gene sequence:

>678_bases
ATGAAAACCGTATTGATCGTCGGCGCATCGCGCGGCCTCGGCCGCGAATTCGTCCGGCAATACCGGCGCGACGGCTGGAA
CGTGATCGCCACCGCACGCGACGCGGCATCGCTCGACGCGCTGCGCGCGCTCGGCGCGCAGCCGCATGCGCTCGACATCG
CGCGGCCCGAGCAGATCGCGGCGCTCGGCTGGAAGCTCGACGGCGAACGGCTCGATGCGGCCGTGCTGGTGTCGGGCGTG
TACGGGCCGCGCACCGAAGGCGTCGAGACGATCACCGCCGAGGATTTCGACGCGGTGATGCATACCAACGTGCGCGGGCC
GATGCAGTTGCTGCCGATCCTGCTGCCGCTCGTCGAGGACGCCCGCGGCGTGCTGGCCGTCGTGTCGAGCCGGATGGGCA
GCATCGCCGAGGCGACCGGCACGACCGGCTGGCTGTACCGCGCGAGCAAGGCCGCGCTGAACGACGCGCTGCGCATCGCG
TCGCTGCAGACGCGCCATGCCGCATGCATTTCGCTGCATCCCGGCTGGGTGCGCACCGACATGGGCGGCGCGCAGGCCGC
GATCGATCCGGAAACGAGCGTGACCGGCATGCGTCGCGTGATCGCCGAATCCGCTTCGGACGTGTCCCAGGCGAACGGCC
GGTTCTTCCAGTACGACGGCGTCGAGCTGAGCTGGTGA

Upstream 100 bases:

>100_bases
CGCTAGCTGCCCGGCGGCGGCTGCCGCGCGGGCGCGGCACGCGTCGAACGGATCTGACACCGGCACCGCCACGGCGGCGC
CAACCCAAGGAGCGACGGGC

Downstream 100 bases:

>100_bases
GTACGCCGGCCGGCAACCCAGCGTTGTTAATTCACATTTCGCATGATTTTGACCCGACCTGACGCGTGCCCGTGCGGCGG
CGCGTCTCCCCCGCCCGCCA

Product: short chain dehydrogenase

Products: NA

Alternate protein names: C signal [H]

Number of amino acids: Translated: 225; Mature: 225

Protein sequence:

>225_residues
MKTVLIVGASRGLGREFVRQYRRDGWNVIATARDAASLDALRALGAQPHALDIARPEQIAALGWKLDGERLDAAVLVSGV
YGPRTEGVETITAEDFDAVMHTNVRGPMQLLPILLPLVEDARGVLAVVSSRMGSIAEATGTTGWLYRASKAALNDALRIA
SLQTRHAACISLHPGWVRTDMGGAQAAIDPETSVTGMRRVIAESASDVSQANGRFFQYDGVELSW

Sequences:

>Translated_225_residues
MKTVLIVGASRGLGREFVRQYRRDGWNVIATARDAASLDALRALGAQPHALDIARPEQIAALGWKLDGERLDAAVLVSGV
YGPRTEGVETITAEDFDAVMHTNVRGPMQLLPILLPLVEDARGVLAVVSSRMGSIAEATGTTGWLYRASKAALNDALRIA
SLQTRHAACISLHPGWVRTDMGGAQAAIDPETSVTGMRRVIAESASDVSQANGRFFQYDGVELSW
>Mature_225_residues
MKTVLIVGASRGLGREFVRQYRRDGWNVIATARDAASLDALRALGAQPHALDIARPEQIAALGWKLDGERLDAAVLVSGV
YGPRTEGVETITAEDFDAVMHTNVRGPMQLLPILLPLVEDARGVLAVVSSRMGSIAEATGTTGWLYRASKAALNDALRIA
SLQTRHAACISLHPGWVRTDMGGAQAAIDPETSVTGMRRVIAESASDVSQANGRFFQYDGVELSW

Specific function: Cell-cell signaling protein required for fruiting body morphogenesis. Necessary for cellular aggregation, for spore differentiation, and for gene expression that is initiated after 6 hour of starvation [H]

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: To yeast YKL071W [H]

Homologues:

Organism=Caenorhabditis elegans, GI17558994, Length=243, Percent_Identity=30.4526748971193, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI193207563, Length=221, Percent_Identity=28.9592760180996, Blast_Score=74, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17558992, Length=246, Percent_Identity=30.0813008130081, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24640547, Length=251, Percent_Identity=29.0836653386454, Blast_Score=95, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 24123; Mature: 24123

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTVLIVGASRGLGREFVRQYRRDGWNVIATARDAASLDALRALGAQPHALDIARPEQIA
CCEEEEEECCCCCCHHHHHHHHHCCCEEEEECCCHHHHHHHHHHCCCCCEEECCCCHHHH
ALGWKLDGERLDAAVLVSGVYGPRTEGVETITAEDFDAVMHTNVRGPMQLLPILLPLVED
HCCEEECCHHHCHHHEEECCCCCCCCCCEEEEHHHHHHHHHCCCCCHHHHHHHHHHHHHH
ARGVLAVVSSRMGSIAEATGTTGWLYRASKAALNDALRIASLQTRHAACISLHPGWVRTD
HHHHHHHHHHHHCCHHHHCCCCHHEEHHHHHHHHHHHHHHHHHHCCEEEEEECCCEEEEC
MGGAQAAIDPETSVTGMRRVIAESASDVSQANGRFFQYDGVELSW
CCCCCEECCCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCEEECC
>Mature Secondary Structure
MKTVLIVGASRGLGREFVRQYRRDGWNVIATARDAASLDALRALGAQPHALDIARPEQIA
CCEEEEEECCCCCCHHHHHHHHHCCCEEEEECCCHHHHHHHHHHCCCCCEEECCCCHHHH
ALGWKLDGERLDAAVLVSGVYGPRTEGVETITAEDFDAVMHTNVRGPMQLLPILLPLVED
HCCEEECCHHHCHHHEEECCCCCCCCCCEEEEHHHHHHHHHCCCCCHHHHHHHHHHHHHH
ARGVLAVVSSRMGSIAEATGTTGWLYRASKAALNDALRIASLQTRHAACISLHPGWVRTD
HHHHHHHHHHHHCCHHHHCCCCHHEEHHHHHHHHHHHHHHHHHHCCEEEEEECCCEEEEC
MGGAQAAIDPETSVTGMRRVIAESASDVSQANGRFFQYDGVELSW
CCCCCEECCCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2152896; 2107980; 2118510; 1372277 [H]