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The map label for this gene is hisC2 [H]

Identifier: 116690825

GI number: 116690825

Start: 3101473

End: 3102540

Strand: Direct

Name: hisC2 [H]

Synonym: Bcen2424_2805

Alternate gene names: 116690825

Gene position: 3101473-3102540 (Clockwise)

Preceding gene: 116690824

Following gene: 116690829

Centisome position: 89.02

GC content: 67.51

Gene sequence:

>1068_bases
GTGAGCCGTTACTGGAGCGATGTCGTTCAGCAACTCGTGCCTTACGTGCCGGGCGAACAGCCCGCGCTCGCGCACCCCGT
CAAGCTGAACACCAACGAGAATCCCTATCCGCCGTCGCCGCGTGTCGTCGCGGCAATCGCACGCGAACTCGGCGAGACCG
GCGACACGCTGCGCCGCTATCCGGACCCGGTCGCGCGCGCACTGCGCGAGACGGTCGCGGCCCATCACCGCATCCAGCCC
GAACAGGTGTTCGTCGGCAATGGCTCCGACGAGGTGCTCGCGCACGCGTTCCAGGCGCTGCTCAAGCACGACCGGCCGCT
GCGCTTTCCCGACATCACGTACAGCTTCTACCCGACCTACGCGCGCCTGTACGGCGTCGAGACCACGGTCGTGCCGCTCG
CGGACGATTTCTCGATCCGCGTCGACGACTATCTCGACGACGCCGGCGGCGTGCTGTTTCCGAACCCGAATGCGCCGACC
GGGCGCGCGCTGCCGCTCGCGGACGTCGAGCGGATCGCGGCCGCGAATCCGTCGTCGGTGGTCGTGATCGACGAAGCGTA
CGTCGATTTCGGCGCGCAGTCGGCCATCACGCTGATCGACCGTCATCCGAACCTGCTCGTCGTGCATACGACGTCGAAGG
CGCGCTCGCTCGCGGGCATGCGCGTCGGCTTCGCGTTCGGCGACGCGGCGCTGATCGACGCGCTGAACCGCGTGAAGGAC
AGCTTCAACTCGTACCCGCTCGACCGGCTCGCGCAGGTTGCCGCGCAGGCCGCGTATGAAGACACCGACTATTTCAACGC
CACCTGCCGGCGCGTGATCGACAGCCGCGCGCGGCTCACGCATGCGCTCGACGCACTCGGCTTCGAGATCGTGCCGTCGG
CCGCGAATTTCGTGTTCGCGCGCCATCCCGCGCACGACGCAAGCGCGATCGCGGCCAAGCTGAAAGAACGGGAAATTTTC
GTGCGGCACTTCCGGCTGCCGCGGATCGACCAGCATCTGCGCATCACCGTCGGCACCGATGCCGAATGCGATGCACTCGT
CGCGGCGTTACGCGAGTTGCTGGCCTGA

Upstream 100 bases:

>100_bases
CGGTAGCGTCGGCCGGCCGGCGCAACCGGGCGGCCTCGCCCGCCCCACCGCGACGCGCACATGCGGTAATCTGGACGCTT
TGCCCGACAGGAGCCAAGCG

Downstream 100 bases:

>100_bases
CACGGAAGAACCGGCGCCGGGCGGCGCCGATCTGAAAGAAAGCGCGACGCGCGCGCCACACAAAGCGCGCGTCAGCGCAG
GATCACGACGCGTCGTCGCC

Product: histidinol-phosphate aminotransferase

Products: NA

Alternate protein names: Imidazole acetol-phosphate transaminase 2 [H]

Number of amino acids: Translated: 355; Mature: 354

Protein sequence:

>355_residues
MSRYWSDVVQQLVPYVPGEQPALAHPVKLNTNENPYPPSPRVVAAIARELGETGDTLRRYPDPVARALRETVAAHHRIQP
EQVFVGNGSDEVLAHAFQALLKHDRPLRFPDITYSFYPTYARLYGVETTVVPLADDFSIRVDDYLDDAGGVLFPNPNAPT
GRALPLADVERIAAANPSSVVVIDEAYVDFGAQSAITLIDRHPNLLVVHTTSKARSLAGMRVGFAFGDAALIDALNRVKD
SFNSYPLDRLAQVAAQAAYEDTDYFNATCRRVIDSRARLTHALDALGFEIVPSAANFVFARHPAHDASAIAAKLKEREIF
VRHFRLPRIDQHLRITVGTDAECDALVAALRELLA

Sequences:

>Translated_355_residues
MSRYWSDVVQQLVPYVPGEQPALAHPVKLNTNENPYPPSPRVVAAIARELGETGDTLRRYPDPVARALRETVAAHHRIQP
EQVFVGNGSDEVLAHAFQALLKHDRPLRFPDITYSFYPTYARLYGVETTVVPLADDFSIRVDDYLDDAGGVLFPNPNAPT
GRALPLADVERIAAANPSSVVVIDEAYVDFGAQSAITLIDRHPNLLVVHTTSKARSLAGMRVGFAFGDAALIDALNRVKD
SFNSYPLDRLAQVAAQAAYEDTDYFNATCRRVIDSRARLTHALDALGFEIVPSAANFVFARHPAHDASAIAAKLKEREIF
VRHFRLPRIDQHLRITVGTDAECDALVAALRELLA
>Mature_354_residues
SRYWSDVVQQLVPYVPGEQPALAHPVKLNTNENPYPPSPRVVAAIARELGETGDTLRRYPDPVARALRETVAAHHRIQPE
QVFVGNGSDEVLAHAFQALLKHDRPLRFPDITYSFYPTYARLYGVETTVVPLADDFSIRVDDYLDDAGGVLFPNPNAPTG
RALPLADVERIAAANPSSVVVIDEAYVDFGAQSAITLIDRHPNLLVVHTTSKARSLAGMRVGFAFGDAALIDALNRVKDS
FNSYPLDRLAQVAAQAAYEDTDYFNATCRRVIDSRARLTHALDALGFEIVPSAANFVFARHPAHDASAIAAKLKEREIFV
RHFRLPRIDQHLRITVGTDAECDALVAALRELLA

Specific function: Histidine biosynthesis; seventh step. [C]

COG id: COG0079

COG function: function code E; Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788332, Length=355, Percent_Identity=31.2676056338028, Blast_Score=132, Evalue=5e-32,
Organism=Escherichia coli, GI1788722, Length=242, Percent_Identity=28.9256198347107, Blast_Score=67, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6322075, Length=363, Percent_Identity=28.3746556473829, Blast_Score=108, Evalue=1e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR005861
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.9 [H]

Molecular weight: Translated: 39097; Mature: 38965

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRYWSDVVQQLVPYVPGEQPALAHPVKLNTNENPYPPSPRVVAAIARELGETGDTLRRY
CCHHHHHHHHHHHCCCCCCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHCCCCHHHHHC
PDPVARALRETVAAHHRIQPEQVFVGNGSDEVLAHAFQALLKHDRPLRFPDITYSFYPTY
CCHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCEECCHHH
ARLYGVETTVVPLADDFSIRVDDYLDDAGGVLFPNPNAPTGRALPLADVERIAAANPSSV
HHHHCCCEEEEEECCCCEEEEHHHHCCCCCEEECCCCCCCCCCCCHHHHHHHHCCCCCCE
VVIDEAYVDFGAQSAITLIDRHPNLLVVHTTSKARSLAGMRVGFAFGDAALIDALNRVKD
EEEEHHHHCCCCCHHEEEEECCCCEEEEEECHHHHHHHHHEEEHHCCHHHHHHHHHHHHH
SFNSYPLDRLAQVAAQAAYEDTDYFNATCRRVIDSRARLTHALDALGFEIVPSAANFVFA
HHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEECCCCCCEEEE
RHPAHDASAIAAKLKEREIFVRHFRLPRIDQHLRITVGTDAECDALVAALRELLA
ECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHHC
>Mature Secondary Structure 
SRYWSDVVQQLVPYVPGEQPALAHPVKLNTNENPYPPSPRVVAAIARELGETGDTLRRY
CHHHHHHHHHHHCCCCCCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHCCCCHHHHHC
PDPVARALRETVAAHHRIQPEQVFVGNGSDEVLAHAFQALLKHDRPLRFPDITYSFYPTY
CCHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCEECCHHH
ARLYGVETTVVPLADDFSIRVDDYLDDAGGVLFPNPNAPTGRALPLADVERIAAANPSSV
HHHHCCCEEEEEECCCCEEEEHHHHCCCCCEEECCCCCCCCCCCCHHHHHHHHCCCCCCE
VVIDEAYVDFGAQSAITLIDRHPNLLVVHTTSKARSLAGMRVGFAFGDAALIDALNRVKD
EEEEHHHHCCCCCHHEEEEECCCCEEEEEECHHHHHHHHHEEEHHCCHHHHHHHHHHHHH
SFNSYPLDRLAQVAAQAAYEDTDYFNATCRRVIDSRARLTHALDALGFEIVPSAANFVFA
HHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEECCCCCCEEEE
RHPAHDASAIAAKLKEREIFVRHFRLPRIDQHLRITVGTDAECDALVAALRELLA
ECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA