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The map label for this gene is pgsA [H]

Identifier: 116689166

GI number: 116689166

Start: 1255919

End: 1256506

Strand: Direct

Name: pgsA [H]

Synonym: Bcen2424_1144

Alternate gene names: 116689166

Gene position: 1255919-1256506 (Clockwise)

Preceding gene: 116689165

Following gene: 116689167

Centisome position: 36.05

GC content: 64.46

Gene sequence:

>588_bases
ATGCCGTTCAATTTCCCGATTTTCCTGACGTGGGTACGGATCGTGCTGATTCCGCTCGTCGTCGGCGTGTTCTATCTGCC
GGACACGGTGATGGGCGGCGCGCACCGCAATCTCGCGGCGGCGGCGATCTTCATCCTCGCCGCGCTGACCGACTGGTTCG
ACGGCTTCCTCGCGCGCAAGTGGAATCAGACGTCGTCGTTCGGTGCCTTTCTCGACCCGGTGGCGGACAAGCTGATGGTG
ACGGCCGCGCTGCTGATCCTCGTGCAGATTTCGCGGGTCGACGCGGCGATCGCGCTGGTGATCGTCGGTCGCGAGATCGC
GATTTCGGCGCTGCGCGAGTGGATGGCGCAGATCGGCGCGTCGAAGAGCGTCGCGGTGAACCAGCTCGGCAAGTTCAAGA
CCGCGTGCCAGATGGTCGCGATTCCGATGCTGCTGTTTTACGGGCCGCTGCCGCTCGGCGTCGTGACGATCGATACGCGC
GTGTGGGGCGAGTGGCTGATGTATCTGGCCGCGGTGCTGACGATCTGGTCGATGCTGTACTACATGAAGCTCGCCTGGCC
GCAGATTCGCGAGCGCGGCGGTGCGTGA

Upstream 100 bases:

>100_bases
AGCTTCACTGACGCGGCCGTGCGGCCGGCTCGTTGCCAGCGTTCTTGTGGCAGGCCGGTCGACACGGCACAATTGCGAAT
CCTTTACTGTCCCGCATGCC

Downstream 100 bases:

>100_bases
GCCGCGCCGGTGCGGCGGCGGTTTTTGTAAAAAGGGCTGGAAAAGCCCTTGACACACGAATGTGCCTTCGACATAATCTC
GCTTCTCCGCTGCACGACGA

Product: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase

Products: NA

Alternate protein names: Phosphatidylglycerophosphate synthase; PGP synthase [H]

Number of amino acids: Translated: 195; Mature: 194

Protein sequence:

>195_residues
MPFNFPIFLTWVRIVLIPLVVGVFYLPDTVMGGAHRNLAAAAIFILAALTDWFDGFLARKWNQTSSFGAFLDPVADKLMV
TAALLILVQISRVDAAIALVIVGREIAISALREWMAQIGASKSVAVNQLGKFKTACQMVAIPMLLFYGPLPLGVVTIDTR
VWGEWLMYLAAVLTIWSMLYYMKLAWPQIRERGGA

Sequences:

>Translated_195_residues
MPFNFPIFLTWVRIVLIPLVVGVFYLPDTVMGGAHRNLAAAAIFILAALTDWFDGFLARKWNQTSSFGAFLDPVADKLMV
TAALLILVQISRVDAAIALVIVGREIAISALREWMAQIGASKSVAVNQLGKFKTACQMVAIPMLLFYGPLPLGVVTIDTR
VWGEWLMYLAAVLTIWSMLYYMKLAWPQIRERGGA
>Mature_194_residues
PFNFPIFLTWVRIVLIPLVVGVFYLPDTVMGGAHRNLAAAAIFILAALTDWFDGFLARKWNQTSSFGAFLDPVADKLMVT
AALLILVQISRVDAAIALVIVGREIAISALREWMAQIGASKSVAVNQLGKFKTACQMVAIPMLLFYGPLPLGVVTIDTRV
WGEWLMYLAAVLTIWSMLYYMKLAWPQIRERGGA

Specific function: This protein catalyzes the committed step to the synthesis of the acidic phospholipids [H]

COG id: COG0558

COG function: function code I; Phosphatidylglycerophosphate synthase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDP-alcohol phosphatidyltransferase class-I family [H]

Homologues:

Organism=Escherichia coli, GI1788220, Length=191, Percent_Identity=48.6910994764398, Blast_Score=154, Evalue=5e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000462
- InterPro:   IPR004570 [H]

Pfam domain/function: PF01066 CDP-OH_P_transf [H]

EC number: =2.7.8.5 [H]

Molecular weight: Translated: 21592; Mature: 21461

Theoretical pI: Translated: 9.77; Mature: 9.77

Prosite motif: PS00379 CDP_ALCOHOL_P_TRANSF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPFNFPIFLTWVRIVLIPLVVGVFYLPDTVMGGAHRNLAAAAIFILAALTDWFDGFLARK
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
WNQTSSFGAFLDPVADKLMVTAALLILVQISRVDAAIALVIVGREIAISALREWMAQIGA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SKSVAVNQLGKFKTACQMVAIPMLLFYGPLPLGVVTIDTRVWGEWLMYLAAVLTIWSMLY
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHH
YMKLAWPQIRERGGA
HHHHHHHHHHHCCCC
>Mature Secondary Structure 
PFNFPIFLTWVRIVLIPLVVGVFYLPDTVMGGAHRNLAAAAIFILAALTDWFDGFLARK
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
WNQTSSFGAFLDPVADKLMVTAALLILVQISRVDAAIALVIVGREIAISALREWMAQIGA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SKSVAVNQLGKFKTACQMVAIPMLLFYGPLPLGVVTIDTRVWGEWLMYLAAVLTIWSMLY
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHH
YMKLAWPQIRERGGA
HHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]