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The map label for this gene is nagZ [H]

Identifier: 116689161

GI number: 116689161

Start: 1248959

End: 1249987

Strand: Direct

Name: nagZ [H]

Synonym: Bcen2424_1139

Alternate gene names: 116689161

Gene position: 1248959-1249987 (Clockwise)

Preceding gene: 116689160

Following gene: 116689165

Centisome position: 35.85

GC content: 69.1

Gene sequence:

>1029_bases
ATGAAAACGACTCCCGGCCCGGTCATGCTCGACGTCGTCGGCACGACCCTGTCGCGCGACGATGCGCGGCGCCTCGCGCA
TCCGAATACCGGCGGCGTGATCCTGTTCGCGCGGCACTTCCAGAATCGCGCGCAACTGACCGCGCTGACCGATGCGATCC
GCGCGGTGCGCGAAGACATCCTGATCGCCGTCGATCACGAAGGCGGGCGCGTGCAGCGGTTCCGCACCGACGGCTTCACG
GTGCTGCCCGCGATGCGCCGCCTCGGCGAACTGTGGGATCGCGACGTGCTGCTCGCGACGAAGGTCGCGACCGCCGTCGG
CTACATCCTGGCCGCCGAATTGCGCGCGTGCGGGATCGACATGAGCTTCACGCCCGTACTCGATCTCGACTACGGGCACT
CGAAGGTGATCGGCGATCGGGCGTTCCATCGCGACCCGCGCGTCGTCACGCTGCTCGCGAAGAGCCTGAATCACGGGTTG
TCGCTCGCCGGTATGGCGAACTGCGGCAAGCATTTCCCCGGACACGGCTTCGCGGAGGCCGATTCGCACGTCGCGTTGCC
GACCGACGACCGCACGCTCGATGCGATCCTCGAGCAGGACGTCGCGCCGTACGACTGGCTCGGGCTGTCGCTTGCCGCGG
TGATTCCGGCGCATGTGATCTACACGCAGGTCGACAAGCGGCCGGCCGGGTTCTCGCGCGTGTGGCTGCAGGACATCCTG
CGCGGCAAGCTCGGCTTCACGGGCGCGATCTTCAGCGACGACCTGTCGATGGAGGCCGCCCGCGAAGGCGGCACGCTCAC
GCAGGCCGCCGATGCCGCGCTCGCCGCCGGTTGCGACATGGTGCTCGTCTGCAACCAGCCGGACGCGGCCGAAGTCGTGC
TGAACGGGCTGAAGGCGCGGGCCTCGGCCGAGTCGGTGCGGCGCCTCAAGCGGATGCGCGCGCGCGGCAAGGCGCTCAAG
TGGGACAAGCTGATCGCGCAGCCCGAGTATCTGCAGGCGCAGGCGCTGCTGAGCAGCGCGCTGGCGTAA

Upstream 100 bases:

>100_bases
GCGGTGTCGTTCGTGGTTGCCGAGACGGACGCTGAAACGGACGCCGCTCCTGCTCCTGTACCTGTTTCCCGAACCTCCTC
CTGACGGAATTCCCGATCTG

Downstream 100 bases:

>100_bases
GCGGGTAGGGGATGGCGCGGGTCGCGCCGTTCCGGTTGCTCCAAACGAAAAAGCCGCGCAGTAGCGCGGCTTTTTTATTA
CCGAGCGCGATGGCCTGATT

Product: beta-hexosaminidase

Products: NA

Alternate protein names: Beta-N-acetylhexosaminidase; N-acetyl-beta-glucosaminidase [H]

Number of amino acids: Translated: 342; Mature: 342

Protein sequence:

>342_residues
MKTTPGPVMLDVVGTTLSRDDARRLAHPNTGGVILFARHFQNRAQLTALTDAIRAVREDILIAVDHEGGRVQRFRTDGFT
VLPAMRRLGELWDRDVLLATKVATAVGYILAAELRACGIDMSFTPVLDLDYGHSKVIGDRAFHRDPRVVTLLAKSLNHGL
SLAGMANCGKHFPGHGFAEADSHVALPTDDRTLDAILEQDVAPYDWLGLSLAAVIPAHVIYTQVDKRPAGFSRVWLQDIL
RGKLGFTGAIFSDDLSMEAAREGGTLTQAADAALAAGCDMVLVCNQPDAAEVVLNGLKARASAESVRRLKRMRARGKALK
WDKLIAQPEYLQAQALLSSALA

Sequences:

>Translated_342_residues
MKTTPGPVMLDVVGTTLSRDDARRLAHPNTGGVILFARHFQNRAQLTALTDAIRAVREDILIAVDHEGGRVQRFRTDGFT
VLPAMRRLGELWDRDVLLATKVATAVGYILAAELRACGIDMSFTPVLDLDYGHSKVIGDRAFHRDPRVVTLLAKSLNHGL
SLAGMANCGKHFPGHGFAEADSHVALPTDDRTLDAILEQDVAPYDWLGLSLAAVIPAHVIYTQVDKRPAGFSRVWLQDIL
RGKLGFTGAIFSDDLSMEAAREGGTLTQAADAALAAGCDMVLVCNQPDAAEVVLNGLKARASAESVRRLKRMRARGKALK
WDKLIAQPEYLQAQALLSSALA
>Mature_342_residues
MKTTPGPVMLDVVGTTLSRDDARRLAHPNTGGVILFARHFQNRAQLTALTDAIRAVREDILIAVDHEGGRVQRFRTDGFT
VLPAMRRLGELWDRDVLLATKVATAVGYILAAELRACGIDMSFTPVLDLDYGHSKVIGDRAFHRDPRVVTLLAKSLNHGL
SLAGMANCGKHFPGHGFAEADSHVALPTDDRTLDAILEQDVAPYDWLGLSLAAVIPAHVIYTQVDKRPAGFSRVWLQDIL
RGKLGFTGAIFSDDLSMEAAREGGTLTQAADAALAAGCDMVLVCNQPDAAEVVLNGLKARASAESVRRLKRMRARGKALK
WDKLIAQPEYLQAQALLSSALA

Specific function: Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides [H]

COG id: COG1472

COG function: function code G; Beta-glucosidase-related glycosidases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 3 family. NagZ subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787350, Length=308, Percent_Identity=47.0779220779221, Blast_Score=246, Evalue=1e-66,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022956
- InterPro:   IPR019800
- InterPro:   IPR001764
- InterPro:   IPR017853 [H]

Pfam domain/function: PF00933 Glyco_hydro_3 [H]

EC number: =3.2.1.52 [H]

Molecular weight: Translated: 37020; Mature: 37020

Theoretical pI: Translated: 8.03; Mature: 8.03

Prosite motif: PS00639 THIOL_PROTEASE_HIS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTTPGPVMLDVVGTTLSRDDARRLAHPNTGGVILFARHFQNRAQLTALTDAIRAVREDI
CCCCCCCEEEEECCCCCCHHHHHHHCCCCCCCEEEEEHHHCCHHHHHHHHHHHHHHHHCE
LIAVDHEGGRVQRFRTDGFTVLPAMRRLGELWDRDVLLATKVATAVGYILAAELRACGID
EEEEECCCCEEEEEECCCEEHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCC
MSFTPVLDLDYGHSKVIGDRAFHRDPRVVTLLAKSLNHGLSLAGMANCGKHFPGHGFAEA
CCCCEEEECCCCCCHHHCCHHHCCCCHHHHHHHHHHCCCCCCHHHHHCCCCCCCCCCCCC
DSHVALPTDDRTLDAILEQDVAPYDWLGLSLAAVIPAHVIYTQVDKRPAGFSRVWLQDIL
CCEEECCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
RGKLGFTGAIFSDDLSMEAAREGGTLTQAADAALAAGCDMVLVCNQPDAAEVVLNGLKAR
HCCCCCCEEEECCCCCHHHHHCCCCHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHH
ASAESVRRLKRMRARGKALKWDKLIAQPEYLQAQALLSSALA
HHHHHHHHHHHHHHHCCCCCHHHHHCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MKTTPGPVMLDVVGTTLSRDDARRLAHPNTGGVILFARHFQNRAQLTALTDAIRAVREDI
CCCCCCCEEEEECCCCCCHHHHHHHCCCCCCCEEEEEHHHCCHHHHHHHHHHHHHHHHCE
LIAVDHEGGRVQRFRTDGFTVLPAMRRLGELWDRDVLLATKVATAVGYILAAELRACGID
EEEEECCCCEEEEEECCCEEHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCC
MSFTPVLDLDYGHSKVIGDRAFHRDPRVVTLLAKSLNHGLSLAGMANCGKHFPGHGFAEA
CCCCEEEECCCCCCHHHCCHHHCCCCHHHHHHHHHHCCCCCCHHHHHCCCCCCCCCCCCC
DSHVALPTDDRTLDAILEQDVAPYDWLGLSLAAVIPAHVIYTQVDKRPAGFSRVWLQDIL
CCEEECCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
RGKLGFTGAIFSDDLSMEAAREGGTLTQAADAALAAGCDMVLVCNQPDAAEVVLNGLKAR
HCCCCCCEEEECCCCCHHHHHCCCCHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHH
ASAESVRRLKRMRARGKALKWDKLIAQPEYLQAQALLSSALA
HHHHHHHHHHHHHHHCCCCCHHHHHCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12910271 [H]