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The map label for this gene is acpS

Identifier: 116689160

GI number: 116689160

Start: 1248496

End: 1248942

Strand: Direct

Name: acpS

Synonym: Bcen2424_1138

Alternate gene names: 116689160

Gene position: 1248496-1248942 (Clockwise)

Preceding gene: 116689159

Following gene: 116689161

Centisome position: 35.84

GC content: 69.35

Gene sequence:

>447_bases
ATGGCGATCTACGGCATCGGTACCGACATCGCGCAGGTGAGCCGCGTCGCGGCCGTGCTCGAACGCACGGGCGGCCGGTT
TGCCGAGAAGGTGCTCGGCCCCGACGAACTGCGCGTGTTCCACGCGCGGCGCGCACGCTCCGAGGCACGCGGCATCGCGT
TTCTCGCGACGCGCTTCTCCGCGAAGGAAGCGTTCTCGAAGGCGATCGGGCTCGGCATGCACTGGCCGATGACGTGGCGC
GCGCTGCAGACGCTCAACCATCCGAGCGGCGAGCCGTACGTGGTCGCATCGGGCGAGCTGGCCGACTGGCTGGCCGCGCG
CGGCATCACGGCGCGCGTGACGGTCAGCGACGAACGCGACTACGCGGTGTCGTTCGTGGTTGCCGAGACGGACGCTGAAA
CGGACGCCGCTCCTGCTCCTGTACCTGTTTCCCGAACCTCCTCCTGA

Upstream 100 bases:

>100_bases
GCACGGCGGCGCGCGCTGACGATGCGAGGCCGCCGCGCCCCGCACGCCGTTTGCGACGCGTTCGCCCCGACGCTGCCGGG
CTACCCCGGCGGAGACTGAC

Downstream 100 bases:

>100_bases
CGGAATTCCCGATCTGATGAAAACGACTCCCGGCCCGGTCATGCTCGACGTCGTCGGCACGACCCTGTCGCGCGACGATG
CGCGGCGCCTCGCGCATCCG

Product: 4'-phosphopantetheinyl transferase

Products: NA

Alternate protein names: Holo-ACP synthase; 4'-phosphopantetheinyl transferase AcpS

Number of amino acids: Translated: 148; Mature: 147

Protein sequence:

>148_residues
MAIYGIGTDIAQVSRVAAVLERTGGRFAEKVLGPDELRVFHARRARSEARGIAFLATRFSAKEAFSKAIGLGMHWPMTWR
ALQTLNHPSGEPYVVASGELADWLAARGITARVTVSDERDYAVSFVVAETDAETDAAPAPVPVSRTSS

Sequences:

>Translated_148_residues
MAIYGIGTDIAQVSRVAAVLERTGGRFAEKVLGPDELRVFHARRARSEARGIAFLATRFSAKEAFSKAIGLGMHWPMTWR
ALQTLNHPSGEPYVVASGELADWLAARGITARVTVSDERDYAVSFVVAETDAETDAAPAPVPVSRTSS
>Mature_147_residues
AIYGIGTDIAQVSRVAAVLERTGGRFAEKVLGPDELRVFHARRARSEARGIAFLATRFSAKEAFSKAIGLGMHWPMTWRA
LQTLNHPSGEPYVVASGELADWLAARGITARVTVSDERDYAVSFVVAETDAETDAAPAPVPVSRTSS

Specific function: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein

COG id: COG0736

COG function: function code I; Phosphopantetheinyl transferase (holo-ACP synthase)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the P-Pant transferase superfamily. AcpS family

Homologues:

Organism=Escherichia coli, GI1788916, Length=131, Percent_Identity=34.3511450381679, Blast_Score=79, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACPS_BURCA (Q1BXT7)

Other databases:

- EMBL:   CP000378
- RefSeq:   YP_620541.1
- ProteinModelPortal:   Q1BXT7
- SMR:   Q1BXT7
- STRING:   Q1BXT7
- GeneID:   4092185
- GenomeReviews:   CP000378_GR
- KEGG:   bcn:Bcen_0658
- eggNOG:   COG0736
- HOGENOM:   HBG734479
- OMA:   QGVFWRD
- ProtClustDB:   PRK00070
- BioCyc:   BCEN331271:BCEN_0658-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00101
- InterPro:   IPR008278
- InterPro:   IPR002582
- InterPro:   IPR004568
- ProDom:   PD004282
- TIGRFAMs:   TIGR00516
- TIGRFAMs:   TIGR00556

Pfam domain/function: PF01648 ACPS; SSF56214 4-PPT_transf

EC number: =2.7.8.7

Molecular weight: Translated: 15931; Mature: 15800

Theoretical pI: Translated: 7.78; Mature: 7.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIYGIGTDIAQVSRVAAVLERTGGRFAEKVLGPDELRVFHARRARSEARGIAFLATRFS
CEEEECCCCHHHHHHHHHHHHHCCCHHHHHHCCHHHHHHHHHHHHHHHHCCEEEEHHHHH
AKEAFSKAIGLGMHWPMTWRALQTLNHPSGEPYVVASGELADWLAARGITARVTVSDERD
HHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCEEEECCCHHHHHHHCCCEEEEEECCCCC
YAVSFVVAETDAETDAAPAPVPVSRTSS
EEEEEEEEECCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
AIYGIGTDIAQVSRVAAVLERTGGRFAEKVLGPDELRVFHARRARSEARGIAFLATRFS
EEEECCCCHHHHHHHHHHHHHCCCHHHHHHCCHHHHHHHHHHHHHHHHCCEEEEHHHHH
AKEAFSKAIGLGMHWPMTWRALQTLNHPSGEPYVVASGELADWLAARGITARVTVSDERD
HHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCEEEECCCHHHHHHHCCCEEEEEECCCCC
YAVSFVVAETDAETDAAPAPVPVSRTSS
EEEEEEEEECCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA