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The map label for this gene is pheA [H]

Identifier: 116689066

GI number: 116689066

Start: 1157012

End: 1158094

Strand: Direct

Name: pheA [H]

Synonym: Bcen2424_1043

Alternate gene names: 116689066

Gene position: 1157012-1158094 (Clockwise)

Preceding gene: 116689065

Following gene: 116689067

Centisome position: 33.21

GC content: 68.42

Gene sequence:

>1083_bases
ATGGACGACGAACTGAATTCCCGCCTGAAACCGCTGCGCGACCGCATCGACGCGATCGACGCGCAGCTGATCGCGCTCCT
GAACCAGCGCGCCGCGGTGGCGCTCGAGGTGGGCGAGGTCAAGAAGCATTTCAACGCGCCGGTGTTCCGGCCGGAGCGCG
AGCTGCAGGTGATCGCGCGGCTGCAGGACATGAGCGGCGGGCCGCTCGCGAGTGAGCACATCAGCGCCATCTGGCGCGAG
ATCATGGCCGCGAGCCGCGCGCTCGAGCAGACGATCCACGTCGCGTTCCTCGGGCCGGTCGGCACGTATAGCGAACAGGC
GATGTTCGAGTATTTCGGCCAGTCGATCGAAGGGCTGCCCTGCCCGTCGATCGATGAGGTGTTCCGCTCGGTCGAGGCCG
GTGCGTCGGCATTCGGCATCGCACCGGTCGAGAATTCGACCGAAGGCGCCGTGTCGCGCACGCTCGACCTGCTGCTGCAG
ACCCAACTGCTGATCAGCGGCGAGCTCGCGCTGCCCATCCATCACAACCTGCTCACGCAGAGCGGCACGCTCGACGGTGT
GAAGCGTGTCTGCGCGCATGCGCAGGCGCTTGCGCAATGCCAGCAGTGGCTCGCGGCGAATGCGCCGCAGCTCGAGCGGC
AGGCCGTGGCGAGCAACGCGGAGGCCGCGCGCCTCGCAGCGGCCGATCCGACCGTCGCCGCGATCGCGGGCGATCGCGCG
GCCGCGCATTACGGCCTGCAGATCGCGTTCTCGCTGATCCAGGACGATCCGCACAACCGTACGCGCTTCGTGATCGTCGG
CAAGCAGCCGGCCGGCCAGAGCGGTCACGACCAGACGTCGCTGATCGTGTCGGTGAAGAACGAGCCGGGCGCCGTGTTCA
AGCTGCTCGAGCCGCTCGCGCGGCACGGCGTGTCGATGACGCGCTTCGAGTCGCGTCCGGCGCGCGTCGGCACGTGGGAG
TACTACTTCTACATCGACATCGAAGGGCACCGCGACGATGCGGCGGTGGCGGCCGCGCTGGCGGAACTCGGCCAGAAGGC
CGCGTTCCTGAAGGTACTCGGTTCGTATCCGCGCGCACGCTGA

Upstream 100 bases:

>100_bases
GGTGCCGCTCGAGGGCGTGAAGGCGCTCGTCGAGTACATGAAGGACTTCGAGCAGCGCGGCGCCTGACGGCGGCGCTGTT
CAAACAGCACGGCAAAACGC

Downstream 100 bases:

>100_bases
TACGCGGCGGCCCGTCGCCTGCTTGGGGCAGGCGTCGTGGCCGGGCGGGCAGGGCAGGCCGGTCGGCGCTGCCGAAGGCG
GGTTCGGGCGGTATCCGGTG

Product: chorismate mutase

Products: NA

Alternate protein names: Chorismate mutase; CM; Prephenate dehydratase; PDT [H]

Number of amino acids: Translated: 360; Mature: 360

Protein sequence:

>360_residues
MDDELNSRLKPLRDRIDAIDAQLIALLNQRAAVALEVGEVKKHFNAPVFRPERELQVIARLQDMSGGPLASEHISAIWRE
IMAASRALEQTIHVAFLGPVGTYSEQAMFEYFGQSIEGLPCPSIDEVFRSVEAGASAFGIAPVENSTEGAVSRTLDLLLQ
TQLLISGELALPIHHNLLTQSGTLDGVKRVCAHAQALAQCQQWLAANAPQLERQAVASNAEAARLAAADPTVAAIAGDRA
AAHYGLQIAFSLIQDDPHNRTRFVIVGKQPAGQSGHDQTSLIVSVKNEPGAVFKLLEPLARHGVSMTRFESRPARVGTWE
YYFYIDIEGHRDDAAVAAALAELGQKAAFLKVLGSYPRAR

Sequences:

>Translated_360_residues
MDDELNSRLKPLRDRIDAIDAQLIALLNQRAAVALEVGEVKKHFNAPVFRPERELQVIARLQDMSGGPLASEHISAIWRE
IMAASRALEQTIHVAFLGPVGTYSEQAMFEYFGQSIEGLPCPSIDEVFRSVEAGASAFGIAPVENSTEGAVSRTLDLLLQ
TQLLISGELALPIHHNLLTQSGTLDGVKRVCAHAQALAQCQQWLAANAPQLERQAVASNAEAARLAAADPTVAAIAGDRA
AAHYGLQIAFSLIQDDPHNRTRFVIVGKQPAGQSGHDQTSLIVSVKNEPGAVFKLLEPLARHGVSMTRFESRPARVGTWE
YYFYIDIEGHRDDAAVAAALAELGQKAAFLKVLGSYPRAR
>Mature_360_residues
MDDELNSRLKPLRDRIDAIDAQLIALLNQRAAVALEVGEVKKHFNAPVFRPERELQVIARLQDMSGGPLASEHISAIWRE
IMAASRALEQTIHVAFLGPVGTYSEQAMFEYFGQSIEGLPCPSIDEVFRSVEAGASAFGIAPVENSTEGAVSRTLDLLLQ
TQLLISGELALPIHHNLLTQSGTLDGVKRVCAHAQALAQCQQWLAANAPQLERQAVASNAEAARLAAADPTVAAIAGDRA
AAHYGLQIAFSLIQDDPHNRTRFVIVGKQPAGQSGHDQTSLIVSVKNEPGAVFKLLEPLARHGVSMTRFESRPARVGTWE
YYFYIDIEGHRDDAAVAAALAELGQKAAFLKVLGSYPRAR

Specific function: L-phenylalanine biosynthesis. [C]

COG id: COG0077

COG function: function code E; Prephenate dehydratase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 prephenate dehydratase domain [H]

Homologues:

Organism=Escherichia coli, GI1788951, Length=373, Percent_Identity=33.2439678284182, Blast_Score=182, Evalue=3e-47,
Organism=Saccharomyces cerevisiae, GI6324013, Length=324, Percent_Identity=25.9259259259259, Blast_Score=90, Evalue=6e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002912
- InterPro:   IPR008242
- InterPro:   IPR002701
- InterPro:   IPR020822
- InterPro:   IPR010957
- InterPro:   IPR001086
- InterPro:   IPR018528 [H]

Pfam domain/function: PF01842 ACT; PF01817 CM_2; PF00800 PDT [H]

EC number: =5.4.99.5; =4.2.1.51 [H]

Molecular weight: Translated: 38982; Mature: 38982

Theoretical pI: Translated: 6.13; Mature: 6.13

Prosite motif: PS00858 PREPHENATE_DEHYDR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDDELNSRLKPLRDRIDAIDAQLIALLNQRAAVALEVGEVKKHFNAPVFRPERELQVIAR
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEEEHHHHHHHHCCCCCCCHHHHHHHHH
LQDMSGGPLASEHISAIWREIMAASRALEQTIHVAFLGPVGTYSEQAMFEYFGQSIEGLP
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCHHHHHHHHHCCCCCCCC
CPSIDEVFRSVEAGASAFGIAPVENSTEGAVSRTLDLLLQTQLLISGELALPIHHNLLTQ
CCCHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEECHHHHHHHC
SGTLDGVKRVCAHAQALAQCQQWLAANAPQLERQAVASNAEAARLAAADPTVAAIAGDRA
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHCCCCCCEEEECCCHH
AAHYGLQIAFSLIQDDPHNRTRFVIVGKQPAGQSGHDQTSLIVSVKNEPGAVFKLLEPLA
HHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHH
RHGVSMTRFESRPARVGTWEYYFYIDIEGHRDDAAVAAALAELGQKAAFLKVLGSYPRAR
HCCCEEEHHCCCCCCCCEEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MDDELNSRLKPLRDRIDAIDAQLIALLNQRAAVALEVGEVKKHFNAPVFRPERELQVIAR
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEEEHHHHHHHHCCCCCCCHHHHHHHHH
LQDMSGGPLASEHISAIWREIMAASRALEQTIHVAFLGPVGTYSEQAMFEYFGQSIEGLP
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCHHHHHHHHHCCCCCCCC
CPSIDEVFRSVEAGASAFGIAPVENSTEGAVSRTLDLLLQTQLLISGELALPIHHNLLTQ
CCCHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEECHHHHHHHC
SGTLDGVKRVCAHAQALAQCQQWLAANAPQLERQAVASNAEAARLAAADPTVAAIAGDRA
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHCCCCCCEEEECCCHH
AAHYGLQIAFSLIQDDPHNRTRFVIVGKQPAGQSGHDQTSLIVSVKNEPGAVFKLLEPLA
HHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHH
RHGVSMTRFESRPARVGTWEYYFYIDIEGHRDDAAVAAALAELGQKAAFLKVLGSYPRAR
HCCCEEEHHCCCCCCCCEEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10094619 [H]