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The map label for this gene is serC [H]

Identifier: 116689065

GI number: 116689065

Start: 1155896

End: 1156978

Strand: Direct

Name: serC [H]

Synonym: Bcen2424_1042

Alternate gene names: 116689065

Gene position: 1155896-1156978 (Clockwise)

Preceding gene: 116689064

Following gene: 116689066

Centisome position: 33.18

GC content: 65.37

Gene sequence:

>1083_bases
ATGCGCGTCTTTAATTTCTCCGCCGGCCCTGCGGCGATGCCCGAGGAAGTGCTGCGGCAGGCCGCCGACGAAATGCTCGA
CTGGCACGGCAGCGGCATGAGCGTGATGGAGATGAGCCATCGCGGCAAGGAATTCATGTCGATCCACGAGGCCGCGCTGA
CCGACCTGCGCGATCTGCTCGGCGTGCCGGCGAGCCACCGGATTCTGTTCCTGCAGGGCGGCGGCATCGCGGAAAACGCG
ATCGTGCCGATGAACCTGCTCGGCGCGCGCAAGACGGCCGACTTCGTCGTGACGGGTTCGTGGTCGCAGAAATCGTTCGG
CGAGGCGAAGAAGTTCTGCGCGCCGCATCTGGCCGCGAGCGGCAAGACGGAGGCCGGCTTCACGCGTGCGCCCGCGCGCG
CCGAATGGCAGCTGTCGGACGATCCGGCCTACGTGCACCTGTGCACCAACGAGACGATCGACGGCGTCGAGACGTTCGAG
ATCCCGGATCTCGGCGACGTGCCGCTGGTTGCCGACGTCTCGTCGCACATCCTGTCGCGCCCGATGGACGTCGCGAAGTA
CGGCGTGCTGTTCGGCGGCGCGCAGAAGAACATCGGGATGGCTGGCGTGACGGTCGTGATCGTGCGCGAGGATCTGCTCG
ATCGCGCGCTGTCGATCTGCCCGTCCGCATTCGAATGGAAGACCATCGCCGCGAACAACTCGCTGTACAACACGCCGCCC
ACCTACGCGATCTACATCGCGGGCCTCGTGTTCCAGTGGCTGAAGCGGCAGGGCGGCCTCGAAGCGATCGAGGCCCGCAA
CATCGAAAAATCGAAGCTGCTCTACGACACGATCGACGCGAGCAGCTTCTATCTGAACAAGGTCGAGCCGGCAGCACGTT
CGCGGATGAACGTGCCGTTTTTCCTGGCCGACGAAACGCGCAACGAAGACTTCCTTGCCGGCGCAAAGGCGCGCGGGCTG
CTGCAGCTGAAGGGCCACAAGTCCGTCGGCGGCATGCGGGCGTCGATCTACAACGCGGTGCCGCTCGAGGGCGTGAAGGC
GCTCGTCGAGTACATGAAGGACTTCGAGCAGCGCGGCGCCTGA

Upstream 100 bases:

>100_bases
GTGCGATAATGGCCGTTTGCGCGCGAGCGCAAGCGGCCATTTCTTTTCTGGCGCGTTTTGCCGGCGGCAAGCCGGTCGCG
TCCCTCCCGAGGTTTTCACG

Downstream 100 bases:

>100_bases
CGGCGGCGCTGTTCAAACAGCACGGCAAAACGCATGGACGACGAACTGAATTCCCGCCTGAAACCGCTGCGCGACCGCAT
CGACGCGATCGACGCGCAGC

Product: phosphoserine aminotransferase

Products: NA

Alternate protein names: Phosphohydroxythreonine aminotransferase; PSAT [H]

Number of amino acids: Translated: 360; Mature: 360

Protein sequence:

>360_residues
MRVFNFSAGPAAMPEEVLRQAADEMLDWHGSGMSVMEMSHRGKEFMSIHEAALTDLRDLLGVPASHRILFLQGGGIAENA
IVPMNLLGARKTADFVVTGSWSQKSFGEAKKFCAPHLAASGKTEAGFTRAPARAEWQLSDDPAYVHLCTNETIDGVETFE
IPDLGDVPLVADVSSHILSRPMDVAKYGVLFGGAQKNIGMAGVTVVIVREDLLDRALSICPSAFEWKTIAANNSLYNTPP
TYAIYIAGLVFQWLKRQGGLEAIEARNIEKSKLLYDTIDASSFYLNKVEPAARSRMNVPFFLADETRNEDFLAGAKARGL
LQLKGHKSVGGMRASIYNAVPLEGVKALVEYMKDFEQRGA

Sequences:

>Translated_360_residues
MRVFNFSAGPAAMPEEVLRQAADEMLDWHGSGMSVMEMSHRGKEFMSIHEAALTDLRDLLGVPASHRILFLQGGGIAENA
IVPMNLLGARKTADFVVTGSWSQKSFGEAKKFCAPHLAASGKTEAGFTRAPARAEWQLSDDPAYVHLCTNETIDGVETFE
IPDLGDVPLVADVSSHILSRPMDVAKYGVLFGGAQKNIGMAGVTVVIVREDLLDRALSICPSAFEWKTIAANNSLYNTPP
TYAIYIAGLVFQWLKRQGGLEAIEARNIEKSKLLYDTIDASSFYLNKVEPAARSRMNVPFFLADETRNEDFLAGAKARGL
LQLKGHKSVGGMRASIYNAVPLEGVKALVEYMKDFEQRGA
>Mature_360_residues
MRVFNFSAGPAAMPEEVLRQAADEMLDWHGSGMSVMEMSHRGKEFMSIHEAALTDLRDLLGVPASHRILFLQGGGIAENA
IVPMNLLGARKTADFVVTGSWSQKSFGEAKKFCAPHLAASGKTEAGFTRAPARAEWQLSDDPAYVHLCTNETIDGVETFE
IPDLGDVPLVADVSSHILSRPMDVAKYGVLFGGAQKNIGMAGVTVVIVREDLLDRALSICPSAFEWKTIAANNSLYNTPP
TYAIYIAGLVFQWLKRQGGLEAIEARNIEKSKLLYDTIDASSFYLNKVEPAARSRMNVPFFLADETRNEDFLAGAKARGL
LQLKGHKSVGGMRASIYNAVPLEGVKALVEYMKDFEQRGA

Specific function: Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine [H]

COG id: COG1932

COG function: function code HE; Phosphoserine aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily [H]

Homologues:

Organism=Homo sapiens, GI17402893, Length=361, Percent_Identity=47.9224376731302, Blast_Score=342, Evalue=3e-94,
Organism=Homo sapiens, GI10863955, Length=357, Percent_Identity=43.4173669467787, Blast_Score=291, Evalue=5e-79,
Organism=Escherichia coli, GI1787136, Length=358, Percent_Identity=54.4692737430168, Blast_Score=405, Evalue=1e-114,
Organism=Caenorhabditis elegans, GI17506897, Length=362, Percent_Identity=45.0276243093923, Blast_Score=328, Evalue=3e-90,
Organism=Saccharomyces cerevisiae, GI6324758, Length=386, Percent_Identity=40.9326424870466, Blast_Score=289, Evalue=4e-79,
Organism=Drosophila melanogaster, GI21356589, Length=359, Percent_Identity=48.7465181058496, Blast_Score=357, Evalue=8e-99,

Paralogues:

None

Copy number: 2500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR020578
- InterPro:   IPR022278
- InterPro:   IPR003248
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.6.1.52 [H]

Molecular weight: Translated: 39289; Mature: 39289

Theoretical pI: Translated: 6.11; Mature: 6.11

Prosite motif: PS00595 AA_TRANSFER_CLASS_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVFNFSAGPAAMPEEVLRQAADEMLDWHGSGMSVMEMSHRGKEFMSIHEAALTDLRDLL
CEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHH
GVPASHRILFLQGGGIAENAIVPMNLLGARKTADFVVTGSWSQKSFGEAKKFCAPHLAAS
CCCCCCEEEEEECCCCCCCCCCCHHHHCCCCCCCEEEECCCCCHHHHHHHHHHCHHHHCC
GKTEAGFTRAPARAEWQLSDDPAYVHLCTNETIDGVETFEIPDLGDVPLVADVSSHILSR
CCCCCCCCCCCCCCEEEECCCCCEEEEECCCCCCCCEEECCCCCCCCCCHHHHHHHHHHC
PMDVAKYGVLFGGAQKNIGMAGVTVVIVREDLLDRALSICPSAFEWKTIAANNSLYNTPP
CHHHHHHHHEECCCCCCCCCCCEEEEEEHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCC
TYAIYIAGLVFQWLKRQGGLEAIEARNIEKSKLLYDTIDASSFYLNKVEPAARSRMNVPF
HHHHHHHHHHHHHHHHCCCCHHHHHCCCCHHHHEEEECCCCHHHHCCCCHHHHHCCCCCE
FLADETRNEDFLAGAKARGLLQLKGHKSVGGMRASIYNAVPLEGVKALVEYMKDFEQRGA
EEECCCCCCCHHCCCCCCCEEEECCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRVFNFSAGPAAMPEEVLRQAADEMLDWHGSGMSVMEMSHRGKEFMSIHEAALTDLRDLL
CEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHH
GVPASHRILFLQGGGIAENAIVPMNLLGARKTADFVVTGSWSQKSFGEAKKFCAPHLAAS
CCCCCCEEEEEECCCCCCCCCCCHHHHCCCCCCCEEEECCCCCHHHHHHHHHHCHHHHCC
GKTEAGFTRAPARAEWQLSDDPAYVHLCTNETIDGVETFEIPDLGDVPLVADVSSHILSR
CCCCCCCCCCCCCCEEEECCCCCEEEEECCCCCCCCEEECCCCCCCCCCHHHHHHHHHHC
PMDVAKYGVLFGGAQKNIGMAGVTVVIVREDLLDRALSICPSAFEWKTIAANNSLYNTPP
CHHHHHHHHEECCCCCCCCCCCEEEEEEHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCC
TYAIYIAGLVFQWLKRQGGLEAIEARNIEKSKLLYDTIDASSFYLNKVEPAARSRMNVPF
HHHHHHHHHHHHHHHHCCCCHHHHHCCCCHHHHEEEECCCCHHHHCCCCHHHHHCCCCCE
FLADETRNEDFLAGAKARGLLQLKGHKSVGGMRASIYNAVPLEGVKALVEYMKDFEQRGA
EEECCCCCCCHHCCCCCCCEEEECCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA