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The map label for this gene is aroE [H]

Identifier: 116688636

GI number: 116688636

Start: 684518

End: 685384

Strand: Direct

Name: aroE [H]

Synonym: Bcen2424_0613

Alternate gene names: 116688636

Gene position: 684518-685384 (Clockwise)

Preceding gene: 116688635

Following gene: 116688637

Centisome position: 19.65

GC content: 72.9

Gene sequence:

>867_bases
ATGAACGCAGTTGCGTCGACGAGCGGCGCCGACCGCTATGTCGTGTTCGGTAACCCGGTGGCGCACAGCAAGTCGCCGTT
CATCCACGCGCAGTTCGCCGCGCAGACCGGCGAGCCGATCGAGTACACGCACCGGCTCGCGCCGGTCGATGGTTTCGAGG
CGGCCGTGCGCGCGTTCGTCGCCGAAGGCGGCCGCGGCGCGAATGTGACGGTGCCGTTCAAGCTCGACGCGCATGCGCTC
GCCGACACGCTGTCGCCGCGCGCGGCGGCCGCAGGCGCGGTGAACACGCTGCGCATCGACGCCGACGGCCGCATCCACGG
CGACAACACCGACGGCGTCGGCCTCGTGCGCGACATCGAAGCGAATCTCGGCGTGTCGCTCGCCGGCGCGCGCATCCTGC
TGCTCGGCGCGGGCGGCGCCGCGCGCGGCGTCGTGCTGCCGCTGCTCGACCGCGCACCGCTGTCGATCGCAATCGTCAAC
CGCACTGCGAGCAAGGCCGAAGCGCTCGTCGGTCAGTTCATGCAGGCCGCGCACGATGCGGGCTGCACGCTCGCGGGCGG
TGGCCCCGGCGTCGTGCGGGCGGAGCCCTACGACGTGGTGATCAATGCGACGGCCGGCAGCCTCGATGCCGCGCTGCCGG
AATGCGACGCAGCCGCGTTCGGCGCCGGCACGCTCGCGTACGACATGATGTACGGCGCGCAGCCGACCGTGTTCATGCAG
CACGCGGCATCGCTCGGCGCGCGCACGGCCGACGGTCTCGGGATGCTCGTCGAGCAGGCGGCCGAGTCGTTCTTCATCTG
GCGCGGCGTGCGGCCGGACGGCGCACCGGTGCTGGCCGCGCTGCGCCAGGCGCTCGCGGCGAGCTGA

Upstream 100 bases:

>100_bases
CGGCGCAAGCCGAGGCCGAAGCGCTGGCCGAATCGGGCGACGCGACGGCGGAGGGCGGCGAAGCCGCGAGCGGCAACGAC
GGCGAAACGGGGCGCGCATC

Downstream 100 bases:

>100_bases
ACGGAGCGCGGCACGTGGTGGCGGTGAGCGGCACGCAGCGCACGCGGACGGTGAGCCTCGCTCGCTGGGCCGTCTACGCG
GGCTCGGTGTTCGCGGGCGC

Product: shikimate 5-dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 288; Mature: 288

Protein sequence:

>288_residues
MNAVASTSGADRYVVFGNPVAHSKSPFIHAQFAAQTGEPIEYTHRLAPVDGFEAAVRAFVAEGGRGANVTVPFKLDAHAL
ADTLSPRAAAAGAVNTLRIDADGRIHGDNTDGVGLVRDIEANLGVSLAGARILLLGAGGAARGVVLPLLDRAPLSIAIVN
RTASKAEALVGQFMQAAHDAGCTLAGGGPGVVRAEPYDVVINATAGSLDAALPECDAAAFGAGTLAYDMMYGAQPTVFMQ
HAASLGARTADGLGMLVEQAAESFFIWRGVRPDGAPVLAALRQALAAS

Sequences:

>Translated_288_residues
MNAVASTSGADRYVVFGNPVAHSKSPFIHAQFAAQTGEPIEYTHRLAPVDGFEAAVRAFVAEGGRGANVTVPFKLDAHAL
ADTLSPRAAAAGAVNTLRIDADGRIHGDNTDGVGLVRDIEANLGVSLAGARILLLGAGGAARGVVLPLLDRAPLSIAIVN
RTASKAEALVGQFMQAAHDAGCTLAGGGPGVVRAEPYDVVINATAGSLDAALPECDAAAFGAGTLAYDMMYGAQPTVFMQ
HAASLGARTADGLGMLVEQAAESFFIWRGVRPDGAPVLAALRQALAAS
>Mature_288_residues
MNAVASTSGADRYVVFGNPVAHSKSPFIHAQFAAQTGEPIEYTHRLAPVDGFEAAVRAFVAEGGRGANVTVPFKLDAHAL
ADTLSPRAAAAGAVNTLRIDADGRIHGDNTDGVGLVRDIEANLGVSLAGARILLLGAGGAARGVVLPLLDRAPLSIAIVN
RTASKAEALVGQFMQAAHDAGCTLAGGGPGVVRAEPYDVVINATAGSLDAALPECDAAAFGAGTLAYDMMYGAQPTVFMQ
HAASLGARTADGLGMLVEQAAESFFIWRGVRPDGAPVLAALRQALAAS

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; fourth step. [C]

COG id: COG0169

COG function: function code E; Shikimate 5-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1789675, Length=278, Percent_Identity=46.7625899280576, Blast_Score=231, Evalue=4e-62,
Organism=Escherichia coli, GI1787983, Length=260, Percent_Identity=30.7692307692308, Blast_Score=99, Evalue=3e-22,
Organism=Saccharomyces cerevisiae, GI6320332, Length=165, Percent_Identity=34.5454545454545, Blast_Score=77, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR011342
- InterPro:   IPR013708
- InterPro:   IPR022893
- InterPro:   IPR006151 [H]

Pfam domain/function: PF01488 Shikimate_DH; PF08501 Shikimate_dh_N [H]

EC number: =1.1.1.25 [H]

Molecular weight: Translated: 29236; Mature: 29236

Theoretical pI: Translated: 5.56; Mature: 5.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAVASTSGADRYVVFGNPVAHSKSPFIHAQFAAQTGEPIEYTHRLAPVDGFEAAVRAFV
CCCCCCCCCCCEEEEECCCCCCCCCCEEEEEEECCCCCCHHHHHCCCCCCHHHHHHHHHH
AEGGRGANVTVPFKLDAHALADTLSPRAAAAGAVNTLRIDADGRIHGDNTDGVGLVRDIE
HCCCCCCEEEEEEEECHHHHHHHCCCHHHHCCCCEEEEECCCCEEECCCCCCCEEEEEEC
ANLGVSLAGARILLLGAGGAARGVVLPLLDRAPLSIAIVNRTASKAEALVGQFMQAAHDA
CCCCEEECCCEEEEEECCCCCCCEEEECCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHC
GCTLAGGGPGVVRAEPYDVVINATAGSLDAALPECDAAAFGAGTLAYDMMYGAQPTVFMQ
CCEEECCCCCCEEECCCEEEEECCCCCCCCCCCCCCCHHCCCHHHHHHHHHCCCCHHHHH
HAASLGARTADGLGMLVEQAAESFFIWRGVRPDGAPVLAALRQALAAS
HHHHHCCCCCCHHHHHHHHHHHHEEEEECCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MNAVASTSGADRYVVFGNPVAHSKSPFIHAQFAAQTGEPIEYTHRLAPVDGFEAAVRAFV
CCCCCCCCCCCEEEEECCCCCCCCCCEEEEEEECCCCCCHHHHHCCCCCCHHHHHHHHHH
AEGGRGANVTVPFKLDAHALADTLSPRAAAAGAVNTLRIDADGRIHGDNTDGVGLVRDIE
HCCCCCCEEEEEEEECHHHHHHHCCCHHHHCCCCEEEEECCCCEEECCCCCCCEEEEEEC
ANLGVSLAGARILLLGAGGAARGVVLPLLDRAPLSIAIVNRTASKAEALVGQFMQAAHDA
CCCCEEECCCEEEEEECCCCCCCEEEECCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHC
GCTLAGGGPGVVRAEPYDVVINATAGSLDAALPECDAAAFGAGTLAYDMMYGAQPTVFMQ
CCEEECCCCCCEEECCCEEEEECCCCCCCCCCCCCCCHHCCCHHHHHHHHHCCCCHHHHH
HAASLGARTADGLGMLVEQAAESFFIWRGVRPDGAPVLAALRQALAAS
HHHHHCCCCCCHHHHHHHHHHHHEEEEECCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA