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The map label for this gene is rnb [H]

Identifier: 116688635

GI number: 116688635

Start: 682437

End: 684521

Strand: Direct

Name: rnb [H]

Synonym: Bcen2424_0612

Alternate gene names: 116688635

Gene position: 682437-684521 (Clockwise)

Preceding gene: 116688634

Following gene: 116688636

Centisome position: 19.59

GC content: 69.02

Gene sequence:

>2085_bases
GTGAACGTTTTCTTCGAGGAATCGGGCAGTTTCAAGGCGGGCAGCGTGCTGTCGCGCCAGGGCGACGCATTTCAGGTCGA
GTTGCCCGGCGGGCGGCGGGCGAAGGTGCGCGCGAAAGACGTGCTGATCGAATTCGACAAGCCGGCCGCGGGCGAACTGA
TGCAGGAGGCCGACACGGCCGCGCAGCAGATCGATCTGGACTTCCTGTGGGAATGCGCGCCGGCCGACGAGTTCGCGTAC
ACGGCGCTGGCCGCCGAGTACTTCGGCGCGACGTACGGCCCGGTCGAGCGCGCGGCGCTGGTGCTGCGGCTGCACGGCTC
GCCCGTCTATTTCCGCCGCAAGGGGCGCGGCCAGTACCAGCGGGCGCCGGAAGAGCAGCTCAAGATGGCGCTCGCATCGC
TCGAGCGCAAGCGCCAGCAGGCGCTGGTGCAGGCGCAGTATGAAGAGGAACTGAAGGCCGGCAAGCTGCCGGAAGCGTTC
GCGGGCAAGGTGCTCGGGCTGCTGACGCGGCCGGACAAGAATTCGATCGAATACAAGGCGATGGAAGCGGCGGCCGGCGC
GCGCGGCGTGTCGCCGGCGCGGCTGATGCTCGACTGCGGCGGCATCGAGTCGCCGCGCGCGCTGCACGAAGCGCGCTTCC
TCGCGGAATTCTTTCCGCATGGCACGGGCTTTCCACCCGTCACGGTCGGCCCGCTGCCGGACGACCTGCCCCGCGCGAAC
GTCGAGGCGTTCTCGATCGACGACGTCACGACCACCGAAATCGACGACGCGTTCTCGGTCGAGCACCTGTCCGACGGCCG
GGTGCGGATCGGCGTGCACATCGCGGCGCCGGCGCTCGGCATCGTGCGCGGCGATCCGGTCGACGCGATCGCGCGCGCGC
GCCTGTCGACGGTCTACATGCCGGGCGACAAGATCACGATGCTGCCGGACGACGTCGTCGACGTGTTCACGCTGAAAGAG
GGCGATTACCGCCCGGCGCTGTCGCTGTACATCATCGTCAACCGCGAGACGCAGGACATCGTCGCGAACGAGACGCGTGC
CGAGCTCGTGTTCGTGAAGAACAACCTGCGCCACAACACGCTCGACGAGCTGGTCACCGAAGAGACGCTCGCGGCCGGCA
CCGGCGACTATCCGCACAAGGACGACATCGCCGTGCTGTGGCCGCTCGCGCAGGCGCTGTTCGAGAAGCGCCAGGTCGCG
CGCGCGGGCTACGGGCTGAAGCGCGAGGTGCAGCGCAACACCGATTACAACTTCTACGTCGAAGGCGAGCACGTGACGAT
CACGCCGCGCCGCCGCGGCTCGCCGCTCGACCTGATCGTGTCGGAGCTCGCGATTCTCGCGAACTCGACCTGGGGCGCGT
TCCTGCACGACCACACGGTGCCGGGCATCTACCGCTCGCAGCGCGGCTTCGGCGCGCCGGGCCCGAAGCGCACGCGGATG
CAGACGACGGCCGCGCCGCACGAAGGCCTCGGCGTCGCGCAGTACGCGTGGAGCACGTCGCCGCTGCGCCGCTACGTCGA
CCTCGTGAACCAGTGGCAACTGCTCGCGTGCGTGCAGCACGGCGTCACCGCGAAGCTCGCCGCGCCGTTCAAGCCGAAGG
ACGCCGAACTCTACGCGGTCGTGCAGGGCTTCGACGATACGTACACGGCCTACGCCGACTACCAGCGCCGGATGGAATAT
TTCTGGTGCCTGCGCTGGCTCAAGCAGGAGCAGAAGAAACAGGTCGTCGCGAGCGTCGTGAAGGGCGATCTCGTGCGCCT
GGAGGAAATCCCGCTGCTGCTGCACGTGCCGGGCCTCGGCGTGCATGCGCGCGGCACGCGCGTGCTGCTCGACGTGATGT
CGCTCGACGAGCTGACGATCGAGGCGTCGGTGCGCCTGTTGAACGTGCTCGACGCGCCGACCGTGACGAGCGGCGACGCG
GCCGACGAAGAGGATGACGCCGAAGGCGGCGACGACACGCTGGTCGACGCGGAAGACGCATCGGCGCAAGCCGAGGCCGA
AGCGCTGGCCGAATCGGGCGACGCGACGGCGGAGGGCGGCGAAGCCGCGAGCGGCAACGACGGCGAAACGGGGCGCGCAT
CATGA

Upstream 100 bases:

>100_bases
GCGACGGAAAGACGTCTTAAACCGGCCGCGTGCCGATCGAATTCCCATCATCATGCGGCGCCGCTGACGCGGCGCCCGGC
AGTCTGAACGAGAGTACTGA

Downstream 100 bases:

>100_bases
ACGCAGTTGCGTCGACGAGCGGCGCCGACCGCTATGTCGTGTTCGGTAACCCGGTGGCGCACAGCAAGTCGCCGTTCATC
CACGCGCAGTTCGCCGCGCA

Product: ribonuclease II

Products: NA

Alternate protein names: Exoribonuclease II; RNase II; Ribonuclease II [H]

Number of amino acids: Translated: 694; Mature: 694

Protein sequence:

>694_residues
MNVFFEESGSFKAGSVLSRQGDAFQVELPGGRRAKVRAKDVLIEFDKPAAGELMQEADTAAQQIDLDFLWECAPADEFAY
TALAAEYFGATYGPVERAALVLRLHGSPVYFRRKGRGQYQRAPEEQLKMALASLERKRQQALVQAQYEEELKAGKLPEAF
AGKVLGLLTRPDKNSIEYKAMEAAAGARGVSPARLMLDCGGIESPRALHEARFLAEFFPHGTGFPPVTVGPLPDDLPRAN
VEAFSIDDVTTTEIDDAFSVEHLSDGRVRIGVHIAAPALGIVRGDPVDAIARARLSTVYMPGDKITMLPDDVVDVFTLKE
GDYRPALSLYIIVNRETQDIVANETRAELVFVKNNLRHNTLDELVTEETLAAGTGDYPHKDDIAVLWPLAQALFEKRQVA
RAGYGLKREVQRNTDYNFYVEGEHVTITPRRRGSPLDLIVSELAILANSTWGAFLHDHTVPGIYRSQRGFGAPGPKRTRM
QTTAAPHEGLGVAQYAWSTSPLRRYVDLVNQWQLLACVQHGVTAKLAAPFKPKDAELYAVVQGFDDTYTAYADYQRRMEY
FWCLRWLKQEQKKQVVASVVKGDLVRLEEIPLLLHVPGLGVHARGTRVLLDVMSLDELTIEASVRLLNVLDAPTVTSGDA
ADEEDDAEGGDDTLVDAEDASAQAEAEALAESGDATAEGGEAASGNDGETGRAS

Sequences:

>Translated_694_residues
MNVFFEESGSFKAGSVLSRQGDAFQVELPGGRRAKVRAKDVLIEFDKPAAGELMQEADTAAQQIDLDFLWECAPADEFAY
TALAAEYFGATYGPVERAALVLRLHGSPVYFRRKGRGQYQRAPEEQLKMALASLERKRQQALVQAQYEEELKAGKLPEAF
AGKVLGLLTRPDKNSIEYKAMEAAAGARGVSPARLMLDCGGIESPRALHEARFLAEFFPHGTGFPPVTVGPLPDDLPRAN
VEAFSIDDVTTTEIDDAFSVEHLSDGRVRIGVHIAAPALGIVRGDPVDAIARARLSTVYMPGDKITMLPDDVVDVFTLKE
GDYRPALSLYIIVNRETQDIVANETRAELVFVKNNLRHNTLDELVTEETLAAGTGDYPHKDDIAVLWPLAQALFEKRQVA
RAGYGLKREVQRNTDYNFYVEGEHVTITPRRRGSPLDLIVSELAILANSTWGAFLHDHTVPGIYRSQRGFGAPGPKRTRM
QTTAAPHEGLGVAQYAWSTSPLRRYVDLVNQWQLLACVQHGVTAKLAAPFKPKDAELYAVVQGFDDTYTAYADYQRRMEY
FWCLRWLKQEQKKQVVASVVKGDLVRLEEIPLLLHVPGLGVHARGTRVLLDVMSLDELTIEASVRLLNVLDAPTVTSGDA
ADEEDDAEGGDDTLVDAEDASAQAEAEALAESGDATAEGGEAASGNDGETGRAS
>Mature_694_residues
MNVFFEESGSFKAGSVLSRQGDAFQVELPGGRRAKVRAKDVLIEFDKPAAGELMQEADTAAQQIDLDFLWECAPADEFAY
TALAAEYFGATYGPVERAALVLRLHGSPVYFRRKGRGQYQRAPEEQLKMALASLERKRQQALVQAQYEEELKAGKLPEAF
AGKVLGLLTRPDKNSIEYKAMEAAAGARGVSPARLMLDCGGIESPRALHEARFLAEFFPHGTGFPPVTVGPLPDDLPRAN
VEAFSIDDVTTTEIDDAFSVEHLSDGRVRIGVHIAAPALGIVRGDPVDAIARARLSTVYMPGDKITMLPDDVVDVFTLKE
GDYRPALSLYIIVNRETQDIVANETRAELVFVKNNLRHNTLDELVTEETLAAGTGDYPHKDDIAVLWPLAQALFEKRQVA
RAGYGLKREVQRNTDYNFYVEGEHVTITPRRRGSPLDLIVSELAILANSTWGAFLHDHTVPGIYRSQRGFGAPGPKRTRM
QTTAAPHEGLGVAQYAWSTSPLRRYVDLVNQWQLLACVQHGVTAKLAAPFKPKDAELYAVVQGFDDTYTAYADYQRRMEY
FWCLRWLKQEQKKQVVASVVKGDLVRLEEIPLLLHVPGLGVHARGTRVLLDVMSLDELTIEASVRLLNVLDAPTVTSGDA
ADEEDDAEGGDDTLVDAEDASAQAEAEALAESGDATAEGGEAASGNDGETGRAS

Specific function: Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction [H]

COG id: COG0557

COG function: function code K; Exoribonuclease R

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S1 motif domain [H]

Homologues:

Organism=Escherichia coli, GI1787542, Length=360, Percent_Identity=26.3888888888889, Blast_Score=80, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011129
- InterPro:   IPR016027
- InterPro:   IPR003029
- InterPro:   IPR022967
- InterPro:   IPR013223
- InterPro:   IPR001900
- InterPro:   IPR022966
- InterPro:   IPR004476
- InterPro:   IPR011804 [H]

Pfam domain/function: PF08206 OB_RNB; PF00773 RNB; PF00575 S1 [H]

EC number: =3.1.13.1 [H]

Molecular weight: Translated: 75997; Mature: 75997

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVFFEESGSFKAGSVLSRQGDAFQVELPGGRRAKVRAKDVLIEFDKPAAGELMQEADTA
CCEEECCCCCCCCCCHHCCCCCEEEEECCCCCEEEEEEEEEEEECCCCCHHHHHHHHHHH
AQQIDLDFLWECAPADEFAYTALAAEYFGATYGPVERAALVLRLHGSPVYFRRKGRGQYQ
HHHCCHHHEEECCCCCHHHHHHHHHHHHCCCCCCHHHEEEEEEECCCEEEEEECCCCCCC
RAPEEQLKMALASLERKRQQALVQAQYEEELKAGKLPEAFAGKVLGLLTRPDKNSIEYKA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHEEECCCCCCCHHHH
MEAAAGARGVSPARLMLDCGGIESPRALHEARFLAEFFPHGTGFPPVTVGPLPDDLPRAN
HHHHCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCCCCCC
VEAFSIDDVTTTEIDDAFSVEHLSDGRVRIGVHIAAPALGIVRGDPVDAIARARLSTVYM
CEEEEECCCEECCCCCCCCHHCCCCCEEEEEEEEECCEEEEECCCCHHHHHHHHHHEEEE
PGDKITMLPDDVVDVFTLKEGDYRPALSLYIIVNRETQDIVANETRAELVFVKNNLRHNT
CCCEEEECCCCCEEEEEECCCCCCCEEEEEEEEECCCHHHHCCCCCEEEEEEECCCCCCH
LDELVTEETLAAGTGDYPHKDDIAVLWPLAQALFEKRQVARAGYGLKREVQRNTDYNFYV
HHHHHHHHHHHCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCEEEE
EGEHVTITPRRRGSPLDLIVSELAILANSTWGAFLHDHTVPGIYRSQRGFGAPGPKRTRM
ECCEEEECCCCCCCCHHHHHHHHHHHHCCCCCHHHCCCCCCCCHHCCCCCCCCCCCCCCE
QTTAAPHEGLGVAQYAWSTSPLRRYVDLVNQWQLLACVQHGVTAKLAAPFKPKDAELYAV
EECCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCEEEEE
VQGFDDTYTAYADYQRRMEYFWCLRWLKQEQKKQVVASVVKGDLVRLEEIPLLLHVPGLG
EECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEHCCCCEEEEECCCC
VHARGTRVLLDVMSLDELTIEASVRLLNVLDAPTVTSGDAADEEDDAEGGDDTLVDAEDA
EECCCCEEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEECCCC
SAQAEAEALAESGDATAEGGEAASGNDGETGRAS
CHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MNVFFEESGSFKAGSVLSRQGDAFQVELPGGRRAKVRAKDVLIEFDKPAAGELMQEADTA
CCEEECCCCCCCCCCHHCCCCCEEEEECCCCCEEEEEEEEEEEECCCCCHHHHHHHHHHH
AQQIDLDFLWECAPADEFAYTALAAEYFGATYGPVERAALVLRLHGSPVYFRRKGRGQYQ
HHHCCHHHEEECCCCCHHHHHHHHHHHHCCCCCCHHHEEEEEEECCCEEEEEECCCCCCC
RAPEEQLKMALASLERKRQQALVQAQYEEELKAGKLPEAFAGKVLGLLTRPDKNSIEYKA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHEEECCCCCCCHHHH
MEAAAGARGVSPARLMLDCGGIESPRALHEARFLAEFFPHGTGFPPVTVGPLPDDLPRAN
HHHHCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCCCCCC
VEAFSIDDVTTTEIDDAFSVEHLSDGRVRIGVHIAAPALGIVRGDPVDAIARARLSTVYM
CEEEEECCCEECCCCCCCCHHCCCCCEEEEEEEEECCEEEEECCCCHHHHHHHHHHEEEE
PGDKITMLPDDVVDVFTLKEGDYRPALSLYIIVNRETQDIVANETRAELVFVKNNLRHNT
CCCEEEECCCCCEEEEEECCCCCCCEEEEEEEEECCCHHHHCCCCCEEEEEEECCCCCCH
LDELVTEETLAAGTGDYPHKDDIAVLWPLAQALFEKRQVARAGYGLKREVQRNTDYNFYV
HHHHHHHHHHHCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCEEEE
EGEHVTITPRRRGSPLDLIVSELAILANSTWGAFLHDHTVPGIYRSQRGFGAPGPKRTRM
ECCEEEECCCCCCCCHHHHHHHHHHHHCCCCCHHHCCCCCCCCHHCCCCCCCCCCCCCCE
QTTAAPHEGLGVAQYAWSTSPLRRYVDLVNQWQLLACVQHGVTAKLAAPFKPKDAELYAV
EECCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCEEEEE
VQGFDDTYTAYADYQRRMEYFWCLRWLKQEQKKQVVASVVKGDLVRLEEIPLLLHVPGLG
EECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEHCCCCEEEEECCCC
VHARGTRVLLDVMSLDELTIEASVRLLNVLDAPTVTSGDAADEEDDAEGGDDTLVDAEDA
EECCCCEEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEECCCC
SAQAEAEALAESGDATAEGGEAASGNDGETGRAS
CHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA