Click here to switch to the map view.

The map label for this gene is aroK [H]

Identifier: 116688416

GI number: 116688416

Start: 438228

End: 438782

Strand: Direct

Name: aroK [H]

Synonym: Bcen2424_0392

Alternate gene names: 116688416

Gene position: 438228-438782 (Clockwise)

Preceding gene: 116688415

Following gene: 116688417

Centisome position: 12.58

GC content: 63.96

Gene sequence:

>555_bases
TTGCAAGCGCGGGACCCACATGCAAACGTATTTTTCGTCGGCCTTATGGGAGCGGGTAAGACCACCGTGGGCCGTGCGGT
CGCGCGTCGTCTCGACAGGACGTTCTTCGACTCCGACCACGAAATCGAGGCCCGCACGGGCGCGCGCATTCCGGTGATCT
TCGAGCTGGAGGGCGAGGCCGGGTTTCGCGATCGCGAAACGCAGGTGATCGCCGAGCTCGCGCAGCGCGAGAACATCGTG
CTCGCGACGGGCGGCGGCGCGGTGCTGCGCCCGGAAAATCGCGACAGCCTGAAAACCAACGGCATCGTCGTCTATCTGCG
CGCCAATCCGCACGATCTGTGGCTGCGCACGCGCAAGGACAAGAACCGCCCGCTGTTGCAGACGGAAGATCCGAAGGGGC
GTCTCGAAGCGCTGTACGAAGTGCGCGACCCGCTGTACCGCGAATGCGCGGATTTCGTCATCGAGACTGGCCGTCCGTCG
GTCAACGGTCTCGTCAACATGGTGCTGATGCAACTCGAACTGGCCGGCGTCATCGCCAAGCCGCTACAAGCATGA

Upstream 100 bases:

>100_bases
GAGGAAACGGGGCCGGAAGCCGCCGGCGCAGGCTCGACAAGGCAGCCGCTTTGCCAGTAAGCTGCGCCACACACCAGCAA
GATTGAAGCAGAGGAAGCCG

Downstream 100 bases:

>100_bases
TTACTGTCAACGTCGATCTGGGCGACCGCGCCTATCCGATTCATATTGGCGCCGGCCTGATCGGCCGCACCGAGCTGTTC
GCGCCCCACATCAAGGGTTC

Product: shikimate kinase

Products: NA

Alternate protein names: SK [H]

Number of amino acids: Translated: 184; Mature: 184

Protein sequence:

>184_residues
MQARDPHANVFFVGLMGAGKTTVGRAVARRLDRTFFDSDHEIEARTGARIPVIFELEGEAGFRDRETQVIAELAQRENIV
LATGGGAVLRPENRDSLKTNGIVVYLRANPHDLWLRTRKDKNRPLLQTEDPKGRLEALYEVRDPLYRECADFVIETGRPS
VNGLVNMVLMQLELAGVIAKPLQA

Sequences:

>Translated_184_residues
MQARDPHANVFFVGLMGAGKTTVGRAVARRLDRTFFDSDHEIEARTGARIPVIFELEGEAGFRDRETQVIAELAQRENIV
LATGGGAVLRPENRDSLKTNGIVVYLRANPHDLWLRTRKDKNRPLLQTEDPKGRLEALYEVRDPLYRECADFVIETGRPS
VNGLVNMVLMQLELAGVIAKPLQA
>Mature_184_residues
MQARDPHANVFFVGLMGAGKTTVGRAVARRLDRTFFDSDHEIEARTGARIPVIFELEGEAGFRDRETQVIAELAQRENIV
LATGGGAVLRPENRDSLKTNGIVVYLRANPHDLWLRTRKDKNRPLLQTEDPKGRLEALYEVRDPLYRECADFVIETGRPS
VNGLVNMVLMQLELAGVIAKPLQA

Specific function: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate [H]

COG id: COG0703

COG function: function code E; Shikimate kinase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate kinase family [H]

Homologues:

Organism=Escherichia coli, GI87082255, Length=166, Percent_Identity=50.6024096385542, Blast_Score=162, Evalue=1e-41,
Organism=Escherichia coli, GI1786587, Length=155, Percent_Identity=39.3548387096774, Blast_Score=93, Evalue=9e-21,

Paralogues:

None

Copy number: 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000623
- InterPro:   IPR023000 [H]

Pfam domain/function: PF01202 SKI [H]

EC number: =2.7.1.71 [H]

Molecular weight: Translated: 20577; Mature: 20577

Theoretical pI: Translated: 7.61; Mature: 7.61

Prosite motif: PS01128 SHIKIMATE_KINASE ; PS00267 TACHYKININ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQARDPHANVFFVGLMGAGKTTVGRAVARRLDRTFFDSDHEIEARTGARIPVIFELEGEA
CCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCEECCCCCCCEEEEEECCCC
GFRDRETQVIAELAQRENIVLATGGGAVLRPENRDSLKTNGIVVYLRANPHDLWLRTRKD
CCCCHHHHHHHHHHHCCCEEEEECCCEEECCCCCCCCCCCCEEEEEECCCCEEEEEECCC
KNRPLLQTEDPKGRLEALYEVRDPLYRECADFVIETGRPSVNGLVNMVLMQLELAGVIAK
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
PLQA
CCCC
>Mature Secondary Structure
MQARDPHANVFFVGLMGAGKTTVGRAVARRLDRTFFDSDHEIEARTGARIPVIFELEGEA
CCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCEECCCCCCCEEEEEECCCC
GFRDRETQVIAELAQRENIVLATGGGAVLRPENRDSLKTNGIVVYLRANPHDLWLRTRKD
CCCCHHHHHHHHHHHCCCEEEEECCCEEECCCCCCCCCCCCEEEEEECCCCEEEEEECCC
KNRPLLQTEDPKGRLEALYEVRDPLYRECADFVIETGRPSVNGLVNMVLMQLELAGVIAK
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
PLQA
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA