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The map label for this gene is aroB [H]

Identifier: 116688417

GI number: 116688417

Start: 438779

End: 439858

Strand: Direct

Name: aroB [H]

Synonym: Bcen2424_0393

Alternate gene names: 116688417

Gene position: 438779-439858 (Clockwise)

Preceding gene: 116688416

Following gene: 116688418

Centisome position: 12.59

GC content: 67.69

Gene sequence:

>1080_bases
ATGATTACTGTCAACGTCGATCTGGGCGACCGCGCCTATCCGATTCATATTGGCGCCGGCCTGATCGGCCGCACCGAGCT
GTTCGCGCCCCACATCAAGGGTTCGTCCGTCACGATCGTCACGAACACGACGGTCGATCCGCTCTATGGCGACGCGCTGC
GCGCGGCGCTCGCGCCGCTCGGCAAGCGTGTGTCGACGGTCGTGCTGCCTGACGGCGAGGCGTACAAGAACTGGGAAACG
CTGAACCTGATCTTCGACGGCCTGCTGACGGATCACGCCGATCGCAAGACGACGCTCGTCGCGCTCGGCGGCGGCGTGGT
CGGCGACATGACCGGCTTTGCCGCCGCGTGCTACATGCGCGGCGTGCCGTTCATCCAGGTACCGACGACGCTGCTGTCGC
AGGTCGATTCGTCGGTCGGCGGCAAGACGGGCATCAACCACCCGCTCGGCAAGAACATGATCGGCGCGTTCTACCAGCCG
CAGGCCGTGATCGCGGACATCGGCGCGTTGACGACGCTGCCCGATCGCGAGCTGGCGGCGGGCGTGGCCGAAGTCATCAA
GACGGGCGCGATCGCCGATGCCGGGTTCTTCGACTGGATCGAGGCGAACGTCGAGGCGCTGAACCGTCGCGAGCCGGCAG
CGCTCGCGCACGCGGTGAAGCGTTCGTGCGAGATCAAGGCGAGCGTCGTCGCGGCCGACGAACGCGAAGGCGGCCTGCGC
GCGATCCTGAATTTCGGCCACACGTTCGGCCATGCGATCGAGGCCGGGCTCGGCTATGGCGAATGGCTGCACGGCGAGGC
GGTCGGCTGCGGGATGGTGATGGCGGGCGACCTGTCGGTGCGGCTCGGCCTCCTCGACGAAGCGTCGCGGCAACGCCTCG
ATGCGGTGATCGCGGCCGCGCATCTGCCGACCCGCGGGCCCGCGCTCGGCGACGCGCGCTACATGGACCTGATGCGCGTC
GACAAGAAGGCCGAGGCCGGCGCGATCAAGTTCATCCTGCTGAAGCGATTCGGCGATACGCTGATCACGCAGGCGCCGGA
CGAAGCGGTATTCGCTACACTGGCGCAGACGACGCGCTAA

Upstream 100 bases:

>100_bases
ATTTCGTCATCGAGACTGGCCGTCCGTCGGTCAACGGTCTCGTCAACATGGTGCTGATGCAACTCGAACTGGCCGGCGTC
ATCGCCAAGCCGCTACAAGC

Downstream 100 bases:

>100_bases
CGCCGGCCCGGATTCGCCGGCGCCCCTGACATGGAGGAGACGTGAGCGAGACATCCAGCAGCACACTGCCCGAAGCCAGC
CGCGCATCCGCTGCGCCGGT

Product: 3-dehydroquinate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 359; Mature: 359

Protein sequence:

>359_residues
MITVNVDLGDRAYPIHIGAGLIGRTELFAPHIKGSSVTIVTNTTVDPLYGDALRAALAPLGKRVSTVVLPDGEAYKNWET
LNLIFDGLLTDHADRKTTLVALGGGVVGDMTGFAAACYMRGVPFIQVPTTLLSQVDSSVGGKTGINHPLGKNMIGAFYQP
QAVIADIGALTTLPDRELAAGVAEVIKTGAIADAGFFDWIEANVEALNRREPAALAHAVKRSCEIKASVVAADEREGGLR
AILNFGHTFGHAIEAGLGYGEWLHGEAVGCGMVMAGDLSVRLGLLDEASRQRLDAVIAAAHLPTRGPALGDARYMDLMRV
DKKAEAGAIKFILLKRFGDTLITQAPDEAVFATLAQTTR

Sequences:

>Translated_359_residues
MITVNVDLGDRAYPIHIGAGLIGRTELFAPHIKGSSVTIVTNTTVDPLYGDALRAALAPLGKRVSTVVLPDGEAYKNWET
LNLIFDGLLTDHADRKTTLVALGGGVVGDMTGFAAACYMRGVPFIQVPTTLLSQVDSSVGGKTGINHPLGKNMIGAFYQP
QAVIADIGALTTLPDRELAAGVAEVIKTGAIADAGFFDWIEANVEALNRREPAALAHAVKRSCEIKASVVAADEREGGLR
AILNFGHTFGHAIEAGLGYGEWLHGEAVGCGMVMAGDLSVRLGLLDEASRQRLDAVIAAAHLPTRGPALGDARYMDLMRV
DKKAEAGAIKFILLKRFGDTLITQAPDEAVFATLAQTTR
>Mature_359_residues
MITVNVDLGDRAYPIHIGAGLIGRTELFAPHIKGSSVTIVTNTTVDPLYGDALRAALAPLGKRVSTVVLPDGEAYKNWET
LNLIFDGLLTDHADRKTTLVALGGGVVGDMTGFAAACYMRGVPFIQVPTTLLSQVDSSVGGKTGINHPLGKNMIGAFYQP
QAVIADIGALTTLPDRELAAGVAEVIKTGAIADAGFFDWIEANVEALNRREPAALAHAVKRSCEIKASVVAADEREGGLR
AILNFGHTFGHAIEAGLGYGEWLHGEAVGCGMVMAGDLSVRLGLLDEASRQRLDAVIAAAHLPTRGPALGDARYMDLMRV
DKKAEAGAIKFILLKRFGDTLITQAPDEAVFATLAQTTR

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; second step. [C]

COG id: COG0337

COG function: function code E; 3-dehydroquinate synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dehydroquinate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1789791, Length=334, Percent_Identity=57.7844311377245, Blast_Score=362, Evalue=1e-101,
Organism=Saccharomyces cerevisiae, GI6320332, Length=368, Percent_Identity=39.1304347826087, Blast_Score=219, Evalue=4e-58,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016303
- InterPro:   IPR002658
- InterPro:   IPR016037 [H]

Pfam domain/function: PF01761 DHQ_synthase [H]

EC number: =4.2.3.4 [H]

Molecular weight: Translated: 37865; Mature: 37865

Theoretical pI: Translated: 6.05; Mature: 6.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITVNVDLGDRAYPIHIGAGLIGRTELFAPHIKGSSVTIVTNTTVDPLYGDALRAALAPL
CEEEEEECCCCEEEEEECCCCCCCHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHH
GKRVSTVVLPDGEAYKNWETLNLIFDGLLTDHADRKTTLVALGGGVVGDMTGFAAACYMR
CCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHC
GVPFIQVPTTLLSQVDSSVGGKTGINHPLGKNMIGAFYQPQAVIADIGALTTLPDRELAA
CCCEEEHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHCCCCCHHHHH
GVAEVIKTGAIADAGFFDWIEANVEALNRREPAALAHAVKRSCEIKASVVAADEREGGLR
HHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCEEEEEEECCCCCCCHH
AILNFGHTFGHAIEAGLGYGEWLHGEAVGCGMVMAGDLSVRLGLLDEASRQRLDAVIAAA
HHHHHCHHHHHHHHHCCCCCCCCCCCCCCCCEEEECCCEEEEEHHHHHHHHHHHHHHHHH
HLPTRGPALGDARYMDLMRVDKKAEAGAIKFILLKRFGDTLITQAPDEAVFATLAQTTR
CCCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHCCHHHCCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MITVNVDLGDRAYPIHIGAGLIGRTELFAPHIKGSSVTIVTNTTVDPLYGDALRAALAPL
CEEEEEECCCCEEEEEECCCCCCCHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHH
GKRVSTVVLPDGEAYKNWETLNLIFDGLLTDHADRKTTLVALGGGVVGDMTGFAAACYMR
CCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHC
GVPFIQVPTTLLSQVDSSVGGKTGINHPLGKNMIGAFYQPQAVIADIGALTTLPDRELAA
CCCEEEHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHCCCCCHHHHH
GVAEVIKTGAIADAGFFDWIEANVEALNRREPAALAHAVKRSCEIKASVVAADEREGGLR
HHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCEEEEEEECCCCCCCHH
AILNFGHTFGHAIEAGLGYGEWLHGEAVGCGMVMAGDLSVRLGLLDEASRQRLDAVIAAA
HHHHHCHHHHHHHHHCCCCCCCCCCCCCCCCEEEECCCEEEEEHHHHHHHHHHHHHHHHH
HLPTRGPALGDARYMDLMRVDKKAEAGAIKFILLKRFGDTLITQAPDEAVFATLAQTTR
CCCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHCCHHHCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA