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The map label for this gene is pilQ [H]

Identifier: 116688415

GI number: 116688415

Start: 436556

End: 438187

Strand: Direct

Name: pilQ [H]

Synonym: Bcen2424_0391

Alternate gene names: 116688415

Gene position: 436556-438187 (Clockwise)

Preceding gene: 116688414

Following gene: 116688416

Centisome position: 12.53

GC content: 70.71

Gene sequence:

>1632_bases
ATGACGAAACACGGCTGTTGGCTATTTGCCATCTGGGCCGGGGTGACGGCGGCCGACGCCGGCGCGTCGTTGCCGCCGCT
GCCCGCGGTCTGGCCCGCCGGGGCGACGGATGTGTCGGTGCCAGGCTTGCCGCAGTCGCTGCGCGTGGCCGACGGCGCGG
ACGGTGCGGTAGCGCAGGACGCCGGCCCGCCGCCATTCGATCAGGCGGCGCGCACGGCACTGCCGACGGAAACCGCCGCA
ACGCCCCCCACGCTGGAGGGACCGCCGATCCCGCTGGCGCCGCCGGCCCGGATGAGCGACGCTGCGGCCCGGCAACCGGG
CGATGCGGACGACGCGCGGCGGATCTCGCTGAATCTGCAGGGCGTCGGGCTCGCGGCCGCATTCGACGCGATCGCGCGGT
TCACGGGGCTCAATATCGTCGTCGGCGAGCAGGTGCGCGGCACGGTGACGTTACGTCTGAATAATGTCCGCTGGCGCGAG
GCGTTCGACACGCTGCTCGACACGCACGGGCTCGCGATGTCCCGGCGCGGCAACGTGATTTGGGTCACACCGGCAGCCGA
GCTGGCTGCGCGCGAACGCGAGCGCTTCGAAATGCATGCGCGGGCCGCCGATCTGGAGCCGCTCGCGAGCCGTACGTTCG
TGCTGCACTATCCCCGCGCGCAGGACGTGCAACGGCTGCTGGCCGGCGCGACCGGCCAGCGCCTGCTGTCGAAGCGCGGT
GCTGCTGCGGCCGATCCCCGCACGAACCTGCTGTTCGTCACCGATCTCGCGCCGCGCATCACGCAGATCGCGGGCCTGAT
CGATGCGATCGACCGGCCGTCGCGGCAGGTCCGGATCGAGGCCCGCATCGTCGAAGGCGAGCAGGGTTTCTCGCGCAACC
TTGGCGCCCGCGTCGCGCTGCGTGCGCAGGGGCGGCCGCCAGCGGCCGAAGGCGCGTCCTTCACGGCGAACGCACGCAAC
GCGCTCGACCTTGCCGCGCGGCCGCTCGGCGGCTTCGACGCGGCGACCGCCGGTTTCACGCTGTTCGCCGCGCCACTCAG
CCGCGTACTCGACATCGAACTGAGCGCGCTCGAGGCGCAGGGACGGGGCCAGATCGTTTCGCGTCCGCGGGTGGTGACGG
CCGATCGCGTCAAGGCCATCGTCGAACAGGGTTCCGAGCTGCCGTACCAGGCGAAGGTCGGCAACGGCATGAGCGGTGTG
CAGTTCCGCCGCGCGACGCTCAAGCTCGAAGTCGAGCCGCAAATCACGCCGGACGGGCGCGTGGTGCTCGATCTCGACGT
GACGAAGGACAGCGTCGGCGAGCCGACCGCGGCCGGCCCCGCCATCCATACGAAGCATGTGCAAACGCGCGTCGAGGTCG
AGAATGGCGGGACGGTCGCGATCGGCGGCATCTATGAACAACTGAACCGGAACGATGTGACGCGGGTGCCACTCTTGGGC
AAAATACCGTTTCTGGGCGCGCTTTTCAGGCACCGCGCGCAGCGCGACCAGCGCAACGAACTGGTCGTTTTCATCACGCC
GACCGTCGTCGATGCGCGTTGCGGCGCACCCGGCGCGGGCGACGCGGATGCCGAGGAAACGGGGCCGGAAGCCGCCGGCG
CAGGCTCGACAAGGCAGCCGCTTTGCCAGTAA

Upstream 100 bases:

>100_bases
TGCTCGGGGCCGCGCGCGTGGTGCGCGTCGAGCGCGCGGCCGTGACGCTTGCGACGGCGGACGGAGCGCAGCGGCTCGTC
CTGGACGACGGAGGCCGGCC

Downstream 100 bases:

>100_bases
GCTGCGCCACACACCAGCAAGATTGAAGCAGAGGAAGCCGTTGCAAGCGCGGGACCCACATGCAAACGTATTTTTCGTCG
GCCTTATGGGAGCGGGTAAG

Product: type IV pilus secretin PilQ

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 543; Mature: 542

Protein sequence:

>543_residues
MTKHGCWLFAIWAGVTAADAGASLPPLPAVWPAGATDVSVPGLPQSLRVADGADGAVAQDAGPPPFDQAARTALPTETAA
TPPTLEGPPIPLAPPARMSDAAARQPGDADDARRISLNLQGVGLAAAFDAIARFTGLNIVVGEQVRGTVTLRLNNVRWRE
AFDTLLDTHGLAMSRRGNVIWVTPAAELAARERERFEMHARAADLEPLASRTFVLHYPRAQDVQRLLAGATGQRLLSKRG
AAAADPRTNLLFVTDLAPRITQIAGLIDAIDRPSRQVRIEARIVEGEQGFSRNLGARVALRAQGRPPAAEGASFTANARN
ALDLAARPLGGFDAATAGFTLFAAPLSRVLDIELSALEAQGRGQIVSRPRVVTADRVKAIVEQGSELPYQAKVGNGMSGV
QFRRATLKLEVEPQITPDGRVVLDLDVTKDSVGEPTAAGPAIHTKHVQTRVEVENGGTVAIGGIYEQLNRNDVTRVPLLG
KIPFLGALFRHRAQRDQRNELVVFITPTVVDARCGAPGAGDADAEETGPEAAGAGSTRQPLCQ

Sequences:

>Translated_543_residues
MTKHGCWLFAIWAGVTAADAGASLPPLPAVWPAGATDVSVPGLPQSLRVADGADGAVAQDAGPPPFDQAARTALPTETAA
TPPTLEGPPIPLAPPARMSDAAARQPGDADDARRISLNLQGVGLAAAFDAIARFTGLNIVVGEQVRGTVTLRLNNVRWRE
AFDTLLDTHGLAMSRRGNVIWVTPAAELAARERERFEMHARAADLEPLASRTFVLHYPRAQDVQRLLAGATGQRLLSKRG
AAAADPRTNLLFVTDLAPRITQIAGLIDAIDRPSRQVRIEARIVEGEQGFSRNLGARVALRAQGRPPAAEGASFTANARN
ALDLAARPLGGFDAATAGFTLFAAPLSRVLDIELSALEAQGRGQIVSRPRVVTADRVKAIVEQGSELPYQAKVGNGMSGV
QFRRATLKLEVEPQITPDGRVVLDLDVTKDSVGEPTAAGPAIHTKHVQTRVEVENGGTVAIGGIYEQLNRNDVTRVPLLG
KIPFLGALFRHRAQRDQRNELVVFITPTVVDARCGAPGAGDADAEETGPEAAGAGSTRQPLCQ
>Mature_542_residues
TKHGCWLFAIWAGVTAADAGASLPPLPAVWPAGATDVSVPGLPQSLRVADGADGAVAQDAGPPPFDQAARTALPTETAAT
PPTLEGPPIPLAPPARMSDAAARQPGDADDARRISLNLQGVGLAAAFDAIARFTGLNIVVGEQVRGTVTLRLNNVRWREA
FDTLLDTHGLAMSRRGNVIWVTPAAELAARERERFEMHARAADLEPLASRTFVLHYPRAQDVQRLLAGATGQRLLSKRGA
AAADPRTNLLFVTDLAPRITQIAGLIDAIDRPSRQVRIEARIVEGEQGFSRNLGARVALRAQGRPPAAEGASFTANARNA
LDLAARPLGGFDAATAGFTLFAAPLSRVLDIELSALEAQGRGQIVSRPRVVTADRVKAIVEQGSELPYQAKVGNGMSGVQ
FRRATLKLEVEPQITPDGRVVLDLDVTKDSVGEPTAAGPAIHTKHVQTRVEVENGGTVAIGGIYEQLNRNDVTRVPLLGK
IPFLGALFRHRAQRDQRNELVVFITPTVVDARCGAPGAGDADAEETGPEAAGAGSTRQPLCQ

Specific function: Essential for the formation of pili. Involved in the biogenesis of type 4 fimbriae probably by serving as a "porthole" allowing passage of the fimbrae through the outer membrane [H]

COG id: COG4796

COG function: function code U; Type II secretory pathway, component HofQ

Gene ontology:

Cell location: Cell outer membrane (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP D family [H]

Homologues:

Organism=Escherichia coli, GI1789793, Length=416, Percent_Identity=33.4134615384615, Blast_Score=202, Evalue=3e-53,
Organism=Escherichia coli, GI87082242, Length=352, Percent_Identity=26.9886363636364, Blast_Score=110, Evalue=3e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001775
- InterPro:   IPR005644
- InterPro:   IPR013355
- InterPro:   IPR011662
- InterPro:   IPR004846
- InterPro:   IPR004845 [H]

Pfam domain/function: PF00263 Secretin; PF03958 Secretin_N; PF07660 STN [H]

EC number: NA

Molecular weight: Translated: 57336; Mature: 57204

Theoretical pI: Translated: 7.64; Mature: 7.64

Prosite motif: PS00875 T2SP_D

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKHGCWLFAIWAGVTAADAGASLPPLPAVWPAGATDVSVPGLPQSLRVADGADGAVAQD
CCCCCEEEEEEECCCEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCC
AGPPPFDQAARTALPTETAATPPTLEGPPIPLAPPARMSDAAARQPGDADDARRISLNLQ
CCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCEEEEEEEC
GVGLAAAFDAIARFTGLNIVVGEQVRGTVTLRLNNVRWREAFDTLLDTHGLAMSRRGNVI
CCCHHHHHHHHHHHCCCEEEECCCCCEEEEEEECCCCHHHHHHHHHHHCCCEEECCCCEE
WVTPAAELAARERERFEMHARAADLEPLASRTFVLHYPRAQDVQRLLAGATGQRLLSKRG
EECCHHHHHHHHHHHHHHHHHHCCCCHHCCCEEEEECCCHHHHHHHHHCCHHHHHHHHCC
AAAADPRTNLLFVTDLAPRITQIAGLIDAIDRPSRQVRIEARIVEGEQGFSRNLGARVAL
CCCCCCCCCEEEEECCCHHHHHHHHHHHHHCCCCCEEEEEEEEEECCCCCCCCCCCEEEE
RAQGRPPAAEGASFTANARNALDLAARPLGGFDAATAGFTLFAAPLSRVLDIELSALEAQ
EECCCCCCCCCCCEECCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEECCC
GRGQIVSRPRVVTADRVKAIVEQGSELPYQAKVGNGMSGVQFRRATLKLEVEPQITPDGR
CCCCEECCCEEECHHHHHHHHHCCCCCCEEEECCCCCCCCEEEEEEEEEEECCCCCCCCC
VVLDLDVTKDSVGEPTAAGPAIHTKHVQTRVEVENGGTVAIGGIYEQLNRNDVTRVPLLG
EEEEEECCCCCCCCCCCCCCCEEEEEEEEEEEECCCCEEEECHHHHHCCCCCCEECCEEC
KIPFLGALFRHRAQRDQRNELVVFITPTVVDARCGAPGAGDADAEETGPEAAGAGSTRQP
CCHHHHHHHHHHHHCCCCCCEEEEEECCEEECCCCCCCCCCCCCHHCCCCCCCCCCCCCC
LCQ
CCC
>Mature Secondary Structure 
TKHGCWLFAIWAGVTAADAGASLPPLPAVWPAGATDVSVPGLPQSLRVADGADGAVAQD
CCCCEEEEEEECCCEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCC
AGPPPFDQAARTALPTETAATPPTLEGPPIPLAPPARMSDAAARQPGDADDARRISLNLQ
CCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCEEEEEEEC
GVGLAAAFDAIARFTGLNIVVGEQVRGTVTLRLNNVRWREAFDTLLDTHGLAMSRRGNVI
CCCHHHHHHHHHHHCCCEEEECCCCCEEEEEEECCCCHHHHHHHHHHHCCCEEECCCCEE
WVTPAAELAARERERFEMHARAADLEPLASRTFVLHYPRAQDVQRLLAGATGQRLLSKRG
EECCHHHHHHHHHHHHHHHHHHCCCCHHCCCEEEEECCCHHHHHHHHHCCHHHHHHHHCC
AAAADPRTNLLFVTDLAPRITQIAGLIDAIDRPSRQVRIEARIVEGEQGFSRNLGARVAL
CCCCCCCCCEEEEECCCHHHHHHHHHHHHHCCCCCEEEEEEEEEECCCCCCCCCCCEEEE
RAQGRPPAAEGASFTANARNALDLAARPLGGFDAATAGFTLFAAPLSRVLDIELSALEAQ
EECCCCCCCCCCCEECCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEECCC
GRGQIVSRPRVVTADRVKAIVEQGSELPYQAKVGNGMSGVQFRRATLKLEVEPQITPDGR
CCCCEECCCEEECHHHHHHHHHCCCCCCEEEECCCCCCCCEEEEEEEEEEECCCCCCCCC
VVLDLDVTKDSVGEPTAAGPAIHTKHVQTRVEVENGGTVAIGGIYEQLNRNDVTRVPLLG
EEEEEECCCCCCCCCCCCCCCEEEEEEEEEEEECCCCEEEECHHHHHCCCCCCEECCEEC
KIPFLGALFRHRAQRDQRNELVVFITPTVVDARCGAPGAGDADAEETGPEAAGAGSTRQP
CCHHHHHHHHHHHHCCCCCCEEEEEECCEEECCCCCCCCCCCCCHHCCCCCCCCCCCCCC
LCQ
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7901733; 10984043 [H]