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The map label for this gene is atoS [C]

Identifier: 116626893

GI number: 116626893

Start: 9870465

End: 9872120

Strand: Direct

Name: atoS [C]

Synonym: Acid_7870

Alternate gene names: 116626893

Gene position: 9870465-9872120 (Clockwise)

Preceding gene: 116626889

Following gene: 116626895

Centisome position: 99.04

GC content: 59.9

Gene sequence:

>1656_bases
GTGCTCGAATACTTTCGGAACCTGTTCTCAACGGAGTTCATGCCTCACGGGATGTGTTACCTCTGGGACCCTGCTGTGCT
CTGGGTCAACGCGGCCTCCGATATCCTGATTAGCGTTTCGTATTATGCGATTCCGTTCCTGCTGTTTTATTTTGTCCGCA
AACGCCGTGACATTACCTTTAACGCGATCTTCGTGGCTTTCGGCATGTTCATCCTCGCGTGCGGAACTACTCACCTCATG
GGCGCGGTCACTATCTGGCACCCAATCTATCGACTCGATGGCGTGATCAAGGCGATCACTGCAATCGCCTCCGCCGCCAC
CTTGGTCATGCTGGTCCCCATGATGCCTGCCCTGATCGCACTGCCCAGCCCCTCTCAACTCGAGAAAGTGAACCGCTCCC
TGGAGCGCGAGGTCGAAGAGCGCCGGAGCGCCGAGGATGAAGTGCGCCGCATAAACGAAGACCTCGAAGAGCGCGTCGCC
AGGCGCACTGCCGAGCACCAGGCTCTCGAAGCCCAGCTCATTCAGTCGCAGAAGATGGAGGCAATCGGCCGGCTCGCCGG
AGGCGTCGCTCACGATTTCAATAACCTCTTGACCGTGATCCTCGGCTACACGGAGATGCTCCGCGAACACCTGGAAGAGG
ATGCGGTTGCACTGGAATTCGGTGACGAGATCCATCTCGCGGCGCACCGGGCCTCCGATCTCACCAACCAGCTGCTTGCG
TTCAGCCGCCGGCAGATGTCGATACCCAGAGTCGTTTCCCTGAACGATGTGGTGAACCAGATCGAAAAGATGCTGCGCCG
TATCATTGGCGAGGACATCCGGCTCGAAACGCTCCTCACCGATTCGATTCAACCAGTGAAGGTGGACCCGACCCACATCC
AGCAGGTGATCATGAATCTCGCGGTCAACGCACGCGACGCCATGCCCACCGGGGGCACGCTCATCATCGAAACCGCGAAC
GTCGAATTGAGCGCGGAGTACGCCGGCCGCCATATCGGGGTCGAAGCCGGCCCATATACCCTGCTCGCTGTCAGTGACAC
CGGCACGGGCATGGATGACGCCACCAAGGCCCGCCTCTTCGAGCCGTTTTTCACTACCAAAGAGCAAGGTAAAGGTACTG
GCCTGGGGCTCTCAATCGTGTATGGAATCATCAAGCAAAGCGGCGGCGAAATTCTGGTGTACAGCGAACCCGGTCACGGA
ACGGCCTTCAAGATCTATCTGCCGGTGGCCACCGCTATCCGCGAAACGCTCGCTCCAGAGATGGAGGAGCGGGACGTCAT
TCCCGCCGCCGAAACCGTTCTCCTGGTGGAAGACGAACCCCAAGTCCGCAGTCTGACCCGAACCATGCTCACCAGCCGGG
GTTATCGCGTGCTGGAAGCCGCGTCCGTCAGCGACGCCCTGAAAATTGTCGCCGAACAGGATCGTCCGATCGACCTCCTG
CTCACCGACATTGTGATGCCGGGAATGAATGGCATGGACCTGGCCCGCGAAGCCGCCGCGGCCCGGCCCGCACTGCGCGT
ACTGTTCATGTCGGGCTACACCGAGGGCGGCGTGATCGACCGTGGCGTGCTTGATTCCGAAACGCCGTTCATCCAGAAGC
CCTTCACGCTGAGCGCGCTCGATCGCAAAATTCGCGAAGTGCTCAGCCCGGTTTAG

Upstream 100 bases:

>100_bases
ACACCGTGAGTCGGATGAAAACATACGATTGAGACGCGGATTCTGTAACATGTTTCTATCCCAGTTTGTACTATTTGGGG
TTTCAATTGAGGAGCTGCCG

Downstream 100 bases:

>100_bases
GGCAGTTAATTAGCGCACTTCCACCCAGTACGGCATTATGCGCAGGAAACCGCCGCGCAGCCAGGCGCGGAACGGCATGC
GTCCCAACACCTGCGCCAAT

Product: integral membrane sensor hybrid histidine kinase

Products: NA

Alternate protein names: Blue-light-activated histidine kinase; Response regulator [H]

Number of amino acids: Translated: 551; Mature: 551

Protein sequence:

>551_residues
MLEYFRNLFSTEFMPHGMCYLWDPAVLWVNAASDILISVSYYAIPFLLFYFVRKRRDITFNAIFVAFGMFILACGTTHLM
GAVTIWHPIYRLDGVIKAITAIASAATLVMLVPMMPALIALPSPSQLEKVNRSLEREVEERRSAEDEVRRINEDLEERVA
RRTAEHQALEAQLIQSQKMEAIGRLAGGVAHDFNNLLTVILGYTEMLREHLEEDAVALEFGDEIHLAAHRASDLTNQLLA
FSRRQMSIPRVVSLNDVVNQIEKMLRRIIGEDIRLETLLTDSIQPVKVDPTHIQQVIMNLAVNARDAMPTGGTLIIETAN
VELSAEYAGRHIGVEAGPYTLLAVSDTGTGMDDATKARLFEPFFTTKEQGKGTGLGLSIVYGIIKQSGGEILVYSEPGHG
TAFKIYLPVATAIRETLAPEMEERDVIPAAETVLLVEDEPQVRSLTRTMLTSRGYRVLEAASVSDALKIVAEQDRPIDLL
LTDIVMPGMNGMDLAREAAAARPALRVLFMSGYTEGGVIDRGVLDSETPFIQKPFTLSALDRKIREVLSPV

Sequences:

>Translated_551_residues
MLEYFRNLFSTEFMPHGMCYLWDPAVLWVNAASDILISVSYYAIPFLLFYFVRKRRDITFNAIFVAFGMFILACGTTHLM
GAVTIWHPIYRLDGVIKAITAIASAATLVMLVPMMPALIALPSPSQLEKVNRSLEREVEERRSAEDEVRRINEDLEERVA
RRTAEHQALEAQLIQSQKMEAIGRLAGGVAHDFNNLLTVILGYTEMLREHLEEDAVALEFGDEIHLAAHRASDLTNQLLA
FSRRQMSIPRVVSLNDVVNQIEKMLRRIIGEDIRLETLLTDSIQPVKVDPTHIQQVIMNLAVNARDAMPTGGTLIIETAN
VELSAEYAGRHIGVEAGPYTLLAVSDTGTGMDDATKARLFEPFFTTKEQGKGTGLGLSIVYGIIKQSGGEILVYSEPGHG
TAFKIYLPVATAIRETLAPEMEERDVIPAAETVLLVEDEPQVRSLTRTMLTSRGYRVLEAASVSDALKIVAEQDRPIDLL
LTDIVMPGMNGMDLAREAAAARPALRVLFMSGYTEGGVIDRGVLDSETPFIQKPFTLSALDRKIREVLSPV
>Mature_551_residues
MLEYFRNLFSTEFMPHGMCYLWDPAVLWVNAASDILISVSYYAIPFLLFYFVRKRRDITFNAIFVAFGMFILACGTTHLM
GAVTIWHPIYRLDGVIKAITAIASAATLVMLVPMMPALIALPSPSQLEKVNRSLEREVEERRSAEDEVRRINEDLEERVA
RRTAEHQALEAQLIQSQKMEAIGRLAGGVAHDFNNLLTVILGYTEMLREHLEEDAVALEFGDEIHLAAHRASDLTNQLLA
FSRRQMSIPRVVSLNDVVNQIEKMLRRIIGEDIRLETLLTDSIQPVKVDPTHIQQVIMNLAVNARDAMPTGGTLIIETAN
VELSAEYAGRHIGVEAGPYTLLAVSDTGTGMDDATKARLFEPFFTTKEQGKGTGLGLSIVYGIIKQSGGEILVYSEPGHG
TAFKIYLPVATAIRETLAPEMEERDVIPAAETVLLVEDEPQVRSLTRTMLTSRGYRVLEAASVSDALKIVAEQDRPIDLL
LTDIVMPGMNGMDLAREAAAARPALRVLFMSGYTEGGVIDRGVLDSETPFIQKPFTLSALDRKIREVLSPV

Specific function: Photosensitive kinase and response regulator that is involved in increased bacterial virulence upon exposure to light [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=242, Percent_Identity=30.5785123966942, Blast_Score=112, Evalue=5e-26,
Organism=Escherichia coli, GI1790436, Length=244, Percent_Identity=28.6885245901639, Blast_Score=109, Evalue=4e-25,
Organism=Escherichia coli, GI1788713, Length=265, Percent_Identity=28.6792452830189, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI87081816, Length=391, Percent_Identity=27.6214833759591, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1790300, Length=254, Percent_Identity=30.7086614173228, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI145693157, Length=276, Percent_Identity=28.6231884057971, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI48994928, Length=223, Percent_Identity=28.2511210762332, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1786912, Length=279, Percent_Identity=27.2401433691756, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI1790861, Length=270, Percent_Identity=28.1481481481481, Blast_Score=66, Evalue=5e-12,
Organism=Escherichia coli, GI1786600, Length=245, Percent_Identity=25.7142857142857, Blast_Score=62, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 61085; Mature: 61085

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEYFRNLFSTEFMPHGMCYLWDPAVLWVNAASDILISVSYYAIPFLLFYFVRKRRDITF
CHHHHHHHHHCCCCCCCCEEEECCEEEEEECCCHHHEEHHHHHHHHHHHHHHHHCCCCHH
NAIFVAFGMFILACGTTHLMGAVTIWHPIYRLDGVIKAITAIASAATLVMLVPMMPALIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
LPSPSQLEKVNRSLEREVEERRSAEDEVRRINEDLEERVARRTAEHQALEAQLIQSQKME
CCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AIGRLAGGVAHDFNNLLTVILGYTEMLREHLEEDAVALEFGDEIHLAAHRASDLTNQLLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCEEEHHHHHHHHHHHHHH
FSRRQMSIPRVVSLNDVVNQIEKMLRRIIGEDIRLETLLTDSIQPVKVDPTHIQQVIMNL
HHHHHCCCCCEEEHHHHHHHHHHHHHHHCCCCCEEEHHHCCCCCCCCCCHHHHHHHHHHH
AVNARDAMPTGGTLIIETANVELSAEYAGRHIGVEAGPYTLLAVSDTGTGMDDATKARLF
HCCCCCCCCCCCEEEEEECCEEEEHHHCCCCCCCCCCCEEEEEEECCCCCCCCHHHHHHH
EPFFTTKEQGKGTGLGLSIVYGIIKQSGGEILVYSEPGHGTAFKIYLPVATAIRETLAPE
HHHHCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEECCCCCCEEEEEEHHHHHHHHHHCCC
MEERDVIPAAETVLLVEDEPQVRSLTRTMLTSRGYRVLEAASVSDALKIVAEQDRPIDLL
CHHCCCCCCCCEEEEECCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCHHHH
LTDIVMPGMNGMDLAREAAAARPALRVLFMSGYTEGGVIDRGVLDSETPFIQKPFTLSAL
HHHHHCCCCCCHHHHHHHHHHCHHHHHHHHCCCCCCCCEECCCCCCCCCCCCCCCCHHHH
DRKIREVLSPV
HHHHHHHHCCC
>Mature Secondary Structure
MLEYFRNLFSTEFMPHGMCYLWDPAVLWVNAASDILISVSYYAIPFLLFYFVRKRRDITF
CHHHHHHHHHCCCCCCCCEEEECCEEEEEECCCHHHEEHHHHHHHHHHHHHHHHCCCCHH
NAIFVAFGMFILACGTTHLMGAVTIWHPIYRLDGVIKAITAIASAATLVMLVPMMPALIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
LPSPSQLEKVNRSLEREVEERRSAEDEVRRINEDLEERVARRTAEHQALEAQLIQSQKME
CCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AIGRLAGGVAHDFNNLLTVILGYTEMLREHLEEDAVALEFGDEIHLAAHRASDLTNQLLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCEEEHHHHHHHHHHHHHH
FSRRQMSIPRVVSLNDVVNQIEKMLRRIIGEDIRLETLLTDSIQPVKVDPTHIQQVIMNL
HHHHHCCCCCEEEHHHHHHHHHHHHHHHCCCCCEEEHHHCCCCCCCCCCHHHHHHHHHHH
AVNARDAMPTGGTLIIETANVELSAEYAGRHIGVEAGPYTLLAVSDTGTGMDDATKARLF
HCCCCCCCCCCCEEEEEECCEEEEHHHCCCCCCCCCCCEEEEEEECCCCCCCCHHHHHHH
EPFFTTKEQGKGTGLGLSIVYGIIKQSGGEILVYSEPGHGTAFKIYLPVATAIRETLAPE
HHHHCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEECCCCCCEEEEEEHHHHHHHHHHCCC
MEERDVIPAAETVLLVEDEPQVRSLTRTMLTSRGYRVLEAASVSDALKIVAEQDRPIDLL
CHHCCCCCCCCEEEEECCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCHHHH
LTDIVMPGMNGMDLAREAAAARPALRVLFMSGYTEGGVIDRGVLDSETPFIQKPFTLSAL
HHHHHCCCCCCHHHHHHHHHHCHHHHHHHHCCCCCCCCEECCCCCCCCCCCCCCCCHHHH
DRKIREVLSPV
HHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA