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The map label for this gene is nreC [H]

Identifier: 116626889

GI number: 116626889

Start: 9867275

End: 9867922

Strand: Direct

Name: nreC [H]

Synonym: Acid_7866

Alternate gene names: 116626889

Gene position: 9867275-9867922 (Clockwise)

Preceding gene: 116626888

Following gene: 116626893

Centisome position: 99.01

GC content: 62.04

Gene sequence:

>648_bases
ATGGCGGTCCGTATTCTGCTCGCCGACGACCACACCATGATGCGGCAGGGGCTGCGCCACATTTTGGAGAGCCGGCCGGA
TTTCGATATCGTCGCCGAAGCCAGTTCAGGTATCGAAGCCGTGGAAGCCGCCCGCACTCACAAACCCGACGTTGCGATTG
TGGACGTGGCCATGAAGGAGCTGAATGGCATCGAGGCGACCGCGCAGATTCTGAAAATCTCCCCGCACACCGCCGTGCTC
ATCCTGAGCATGTACAGCGACGAACGCTACGTGCTGCGCGCGGTAAAGGCCGGAGCGCGCGGCTACGTGCTCAAGAACTC
CGCCGGAGACGAGTTGATCCAGGCGATCCACGCCGTCCAGCGCGGCCTGGCATTTTTCAGCCCTGCCGTCGCGCGGATCT
TCCAGGATGGCGTCGCCCGCCTGCAGGATGCGCGCGAGGTTTCCGACCGCTTCGAAAGCCTGACCGGCCGCGAACGCCAG
GTTTATCAATTGCTCGCCGAAGGCAACAGTAATAAAGAGATCGCCAACCGCCTCAACCTGAGTCTCCACACCGTGGAAAC
CCACCGCTGGCACATCATGGAGAAGCTCGATCTCCACAGCACGGCCGAGTTGGTACTCAGCGCAGTCCGTCGCGGCTTGG
TGACGTAG

Upstream 100 bases:

>100_bases
ACGTAGGCGGCTCGCTGGTCATCGATTCCGCTCCCCGTCACGGAACCCGGGTTGCTCTCCGCATTCCGCTGGCGCCTCTG
GCGATCGAGGTTCAAACGTG

Downstream 100 bases:

>100_bases
CCTCCTAGTTTTGGTTTTCGGCTTCGCGATCCAGCCCTTCGCGGTCCAGGATCTCCAGTTGATGGCCCTGAATGCGCACC
AGCCCCATCGACCGGAACCG

Product: two component LuxR family transcriptional regulator

Products: NA

Alternate protein names: Nitrogen regulation protein C [H]

Number of amino acids: Translated: 215; Mature: 214

Protein sequence:

>215_residues
MAVRILLADDHTMMRQGLRHILESRPDFDIVAEASSGIEAVEAARTHKPDVAIVDVAMKELNGIEATAQILKISPHTAVL
ILSMYSDERYVLRAVKAGARGYVLKNSAGDELIQAIHAVQRGLAFFSPAVARIFQDGVARLQDAREVSDRFESLTGRERQ
VYQLLAEGNSNKEIANRLNLSLHTVETHRWHIMEKLDLHSTAELVLSAVRRGLVT

Sequences:

>Translated_215_residues
MAVRILLADDHTMMRQGLRHILESRPDFDIVAEASSGIEAVEAARTHKPDVAIVDVAMKELNGIEATAQILKISPHTAVL
ILSMYSDERYVLRAVKAGARGYVLKNSAGDELIQAIHAVQRGLAFFSPAVARIFQDGVARLQDAREVSDRFESLTGRERQ
VYQLLAEGNSNKEIANRLNLSLHTVETHRWHIMEKLDLHSTAELVLSAVRRGLVT
>Mature_214_residues
AVRILLADDHTMMRQGLRHILESRPDFDIVAEASSGIEAVEAARTHKPDVAIVDVAMKELNGIEATAQILKISPHTAVLI
LSMYSDERYVLRAVKAGARGYVLKNSAGDELIQAIHAVQRGLAFFSPAVARIFQDGVARLQDAREVSDRFESLTGRERQV
YQLLAEGNSNKEIANRLNLSLHTVETHRWHIMEKLDLHSTAELVLSAVRRGLVT

Specific function: Member of the two-component regulatory system nreB/nreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. Phosphorylated nreC binds to a GC-rich palindromic sequence at the promoters of the nitrate (narGHJI) and nit

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788222, Length=213, Percent_Identity=32.8638497652582, Blast_Score=130, Evalue=8e-32,
Organism=Escherichia coli, GI1790102, Length=202, Percent_Identity=36.6336633663366, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1788521, Length=214, Percent_Identity=33.6448598130841, Blast_Score=110, Evalue=9e-26,
Organism=Escherichia coli, GI1787473, Length=185, Percent_Identity=34.5945945945946, Blast_Score=103, Evalue=9e-24,
Organism=Escherichia coli, GI1788712, Length=206, Percent_Identity=30.0970873786408, Blast_Score=99, Evalue=1e-22,
Organism=Escherichia coli, GI1786747, Length=201, Percent_Identity=28.8557213930348, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1788546, Length=213, Percent_Identity=26.7605633802817, Blast_Score=67, Evalue=6e-13,
Organism=Escherichia coli, GI87082052, Length=103, Percent_Identity=28.1553398058252, Blast_Score=60, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 23884; Mature: 23753

Theoretical pI: Translated: 7.04; Mature: 7.04

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVRILLADDHTMMRQGLRHILESRPDFDIVAEASSGIEAVEAARTHKPDVAIVDVAMKE
CEEEEEEECCHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHCCCCCHHHHHHHHHH
LNGIEATAQILKISPHTAVLILSMYSDERYVLRAVKAGARGYVLKNSAGDELIQAIHAVQ
HCCHHHHHHHHEECCCCEEEEEEECCCCHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHH
RGLAFFSPAVARIFQDGVARLQDAREVSDRFESLTGRERQVYQLLAEGNSNKEIANRLNL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHCC
SLHTVETHRWHIMEKLDLHSTAELVLSAVRRGLVT
EEEEECHHHHHHHHHHCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AVRILLADDHTMMRQGLRHILESRPDFDIVAEASSGIEAVEAARTHKPDVAIVDVAMKE
EEEEEEECCHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHCCCCCHHHHHHHHHH
LNGIEATAQILKISPHTAVLILSMYSDERYVLRAVKAGARGYVLKNSAGDELIQAIHAVQ
HCCHHHHHHHHEECCCCEEEEEEECCCCHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHH
RGLAFFSPAVARIFQDGVARLQDAREVSDRFESLTGRERQVYQLLAEGNSNKEIANRLNL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHCC
SLHTVETHRWHIMEKLDLHSTAELVLSAVRRGLVT
EEEEECHHHHHHHHHHCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12426351 [H]