Click here to switch to the map view.

The map label for this gene is sufC [H]

Identifier: 116626728

GI number: 116626728

Start: 9674223

End: 9674996

Strand: Direct

Name: sufC [H]

Synonym: Acid_7700

Alternate gene names: 116626728

Gene position: 9674223-9674996 (Clockwise)

Preceding gene: 116626727

Following gene: 116626729

Centisome position: 97.08

GC content: 61.5

Gene sequence:

>774_bases
ATGGCACTACTCGAAATCAAAGATCTGCACGCCAAAGTCGGCGAACGTGAAATTCTGAAGGGCATCAATCTCACCGTGAA
CGCGGGCGAGGTACACGCCATCATGGGGCCCAACGGCAGCGGCAAGAGCACGCTCGCCCAGGTGCTCGCCGGACGCGATA
TGTACGCCGTCACCGGCGGCTCCGTCACTTACGACGGCAAAGACCTGCTGGAGCTCTCCCCCGAAGACCGCGCCCGCGAA
GGCATCTTCCTCGCCTTCCAGTATCCGGTCGAAATTCCGGGGGTCAGCAACATGTACTTCCTGAAGGCCGCGCTCAACGC
CACCCGCAAACACCGCGGCATCGAAGAGCTCGACGCCATGGACTTCCTCAACGTGGTCCGCGAAAAAATGCAGATCATGA
AGATGGATCAGGCGCTGCTCAATCGCCCCGTCAACACCGGGTTCTCCGGCGGCGAAAAGAAGCGCAACGAAATCTTCCAG
ATGGCCGTGCTCGAACCCCGCCTGGCCATCCTAGATGAAACCGATTCCGGCCTCGATATCGACGCCCTGCGCACCGTCGC
GGGCGGCGTCAACGCCATGCGCAGCCCCGATCGCGGCATGATCGTAGTCACCCACTACCAGCGCCTGCTCAGCGAAATCG
TTCCCGATTTCGTCCACGTTCTGGCCGAAGGCCGCATCGTCAAATCCGGCGGCAAGGAACTCGCGCTCGAACTCGAAGCC
GAAGGCTACGAAGGCCTGGGCCTGCATGATGAGCCGGAGGCGGTCGGAAGATGA

Upstream 100 bases:

>100_bases
AAGGAAGTCTTCCGCGAACTCCCCATGGAATTCGCCGTGGAAGCCCAGAAATTGCTCGGAGTCAGTCTCGAAGGAAGCGT
TGGTTAAGAGAAACAAGCGA

Downstream 100 bases:

>100_bases
CGGCAGTCTCGGAACAAACCGGCGCCTGGTTGGAGCAGTTCACCAATCAACCCGCCGCGCCCGCGTGGCTCCAGCCCCTC
CGCGATAACGCCTTCCGCCG

Product: Iron-regulated ABC transporter ATPase SufC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 257; Mature: 256

Protein sequence:

>257_residues
MALLEIKDLHAKVGEREILKGINLTVNAGEVHAIMGPNGSGKSTLAQVLAGRDMYAVTGGSVTYDGKDLLELSPEDRARE
GIFLAFQYPVEIPGVSNMYFLKAALNATRKHRGIEELDAMDFLNVVREKMQIMKMDQALLNRPVNTGFSGGEKKRNEIFQ
MAVLEPRLAILDETDSGLDIDALRTVAGGVNAMRSPDRGMIVVTHYQRLLSEIVPDFVHVLAEGRIVKSGGKELALELEA
EGYEGLGLHDEPEAVGR

Sequences:

>Translated_257_residues
MALLEIKDLHAKVGEREILKGINLTVNAGEVHAIMGPNGSGKSTLAQVLAGRDMYAVTGGSVTYDGKDLLELSPEDRARE
GIFLAFQYPVEIPGVSNMYFLKAALNATRKHRGIEELDAMDFLNVVREKMQIMKMDQALLNRPVNTGFSGGEKKRNEIFQ
MAVLEPRLAILDETDSGLDIDALRTVAGGVNAMRSPDRGMIVVTHYQRLLSEIVPDFVHVLAEGRIVKSGGKELALELEA
EGYEGLGLHDEPEAVGR
>Mature_256_residues
ALLEIKDLHAKVGEREILKGINLTVNAGEVHAIMGPNGSGKSTLAQVLAGRDMYAVTGGSVTYDGKDLLELSPEDRAREG
IFLAFQYPVEIPGVSNMYFLKAALNATRKHRGIEELDAMDFLNVVREKMQIMKMDQALLNRPVNTGFSGGEKKRNEIFQM
AVLEPRLAILDETDSGLDIDALRTVAGGVNAMRSPDRGMIVVTHYQRLLSEIVPDFVHVLAEGRIVKSGGKELALELEAE
GYEGLGLHDEPEAVGR

Specific function: Has low ATPase activity. The SufBCD complex acts synergistically with SufE to stimulate the cysteine desulfurase activity of SufS. The SufBCD complex contributes to the assembly or repair of oxygen-labile iron-sulfur clusters under oxidative stress. May f

COG id: COG0396

COG function: function code O; ABC-type transport system involved in Fe-S cluster assembly, ATPase component

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI9961252, Length=234, Percent_Identity=29.0598290598291, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI4505771, Length=234, Percent_Identity=29.0598290598291, Blast_Score=75, Evalue=4e-14,
Organism=Homo sapiens, GI9961250, Length=234, Percent_Identity=29.0598290598291, Blast_Score=75, Evalue=4e-14,
Organism=Homo sapiens, GI42741659, Length=235, Percent_Identity=28.0851063829787, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI156105685, Length=220, Percent_Identity=29.0909090909091, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI255708477, Length=217, Percent_Identity=29.4930875576037, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI153792144, Length=175, Percent_Identity=29.1428571428571, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI73747915, Length=217, Percent_Identity=29.4930875576037, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI21536378, Length=224, Percent_Identity=27.6785714285714, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI171184400, Length=238, Percent_Identity=26.4705882352941, Blast_Score=66, Evalue=4e-11,
Organism=Escherichia coli, GI1787972, Length=244, Percent_Identity=64.7540983606557, Blast_Score=324, Evalue=4e-90,
Organism=Escherichia coli, GI1787370, Length=217, Percent_Identity=25.3456221198157, Blast_Score=71, Evalue=9e-14,
Organism=Escherichia coli, GI1789672, Length=234, Percent_Identity=26.0683760683761, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1790525, Length=223, Percent_Identity=28.6995515695067, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1790467, Length=237, Percent_Identity=32.0675105485232, Blast_Score=67, Evalue=8e-13,
Organism=Escherichia coli, GI1788761, Length=228, Percent_Identity=25, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1786698, Length=204, Percent_Identity=25.9803921568627, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1787792, Length=235, Percent_Identity=24.2553191489362, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI87081709, Length=237, Percent_Identity=26.1603375527426, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1789891, Length=219, Percent_Identity=28.310502283105, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI87082267, Length=166, Percent_Identity=29.5180722891566, Blast_Score=64, Evalue=8e-12,
Organism=Escherichia coli, GI1787759, Length=244, Percent_Identity=26.2295081967213, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI87081834, Length=197, Percent_Identity=27.9187817258883, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1787029, Length=236, Percent_Identity=23.3050847457627, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1790190, Length=227, Percent_Identity=24.6696035242291, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI48994883, Length=250, Percent_Identity=28.4, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI1786345, Length=199, Percent_Identity=29.6482412060301, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI1786654, Length=233, Percent_Identity=26.6094420600858, Blast_Score=61, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI193209708, Length=232, Percent_Identity=30.1724137931034, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI193202349, Length=237, Percent_Identity=31.6455696202532, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17558664, Length=260, Percent_Identity=28.0769230769231, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI212646699, Length=236, Percent_Identity=25, Blast_Score=74, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI25146777, Length=227, Percent_Identity=25.9911894273128, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI193211017, Length=220, Percent_Identity=29.5454545454545, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71996809, Length=220, Percent_Identity=29.5454545454545, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI193211015, Length=220, Percent_Identity=29.5454545454545, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17565938, Length=218, Percent_Identity=26.605504587156, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17567265, Length=219, Percent_Identity=28.7671232876712, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI115533592, Length=240, Percent_Identity=27.9166666666667, Blast_Score=65, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI115535101, Length=223, Percent_Identity=29.5964125560538, Blast_Score=64, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6323217, Length=222, Percent_Identity=28.3783783783784, Blast_Score=63, Evalue=4e-11,
Organism=Drosophila melanogaster, GI21357907, Length=221, Percent_Identity=28.0542986425339, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI281363262, Length=217, Percent_Identity=29.4930875576037, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24653245, Length=217, Percent_Identity=29.4930875576037, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24659289, Length=252, Percent_Identity=25.7936507936508, Blast_Score=64, Evalue=7e-11,
Organism=Drosophila melanogaster, GI17136662, Length=245, Percent_Identity=25.7142857142857, Blast_Score=64, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593
- InterPro:   IPR010230 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 28085; Mature: 27954

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: PS00785 5_NUCLEOTIDASE_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALLEIKDLHAKVGEREILKGINLTVNAGEVHAIMGPNGSGKSTLAQVLAGRDMYAVTGG
CCEEEHHHHHHHCCHHHHHCCCCEEEECCEEEEEECCCCCCHHHHHHHHCCCCEEEEECC
SVTYDGKDLLELSPEDRAREGIFLAFQYPVEIPGVSNMYFLKAALNATRKHRGIEELDAM
EEEECCCHHEECCCCCCCCCCEEEEEECCEECCCCCCHHHHHHHHHHHHHHCCHHHHHHH
DFLNVVREKMQIMKMDQALLNRPVNTGFSGGEKKRNEIFQMAVLEPRLAILDETDSGLDI
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCCH
DALRTVAGGVNAMRSPDRGMIVVTHYQRLLSEIVPDFVHVLAEGRIVKSGGKELALELEA
HHHHHHHHCHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHCCEEEECCCCEEEEEEEC
EGYEGLGLHDEPEAVGR
CCCCCCCCCCCCHHCCC
>Mature Secondary Structure 
ALLEIKDLHAKVGEREILKGINLTVNAGEVHAIMGPNGSGKSTLAQVLAGRDMYAVTGG
CEEEHHHHHHHCCHHHHHCCCCEEEECCEEEEEECCCCCCHHHHHHHHCCCCEEEEECC
SVTYDGKDLLELSPEDRAREGIFLAFQYPVEIPGVSNMYFLKAALNATRKHRGIEELDAM
EEEECCCHHEECCCCCCCCCCEEEEEECCEECCCCCCHHHHHHHHHHHHHHCCHHHHHHH
DFLNVVREKMQIMKMDQALLNRPVNTGFSGGEKKRNEIFQMAVLEPRLAILDETDSGLDI
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCCH
DALRTVAGGVNAMRSPDRGMIVVTHYQRLLSEIVPDFVHVLAEGRIVKSGGKELALELEA
HHHHHHHHCHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHCCEEEECCCCEEEEEEEC
EGYEGLGLHDEPEAVGR
CCCCCCCCCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 10322040 [H]