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The map label for this gene is aroB

Identifier: 116626384

GI number: 116626384

Start: 9223211

End: 9224284

Strand: Direct

Name: aroB

Synonym: Acid_7344

Alternate gene names: 116626384

Gene position: 9223211-9224284 (Clockwise)

Preceding gene: 116626383

Following gene: 116626385

Centisome position: 92.55

GC content: 63.78

Gene sequence:

>1074_bases
ATGCCCTCTTATCTGGTCGAAACGCCGCAGCGGTGCTATTCCGCCATCGTGGAACGCGGCATCATCGGGCAGACAGCGCA
GTACCTCCCGCCCAAGACCGGCAAGGTCTTCGTTGTCACTACCGCGGATGTCTGGAAGCACGCCGGAGCGCCCCTGAAGG
CCGCGCTGGCCGGTATCCCGTTCGAAATCCTCAATCTTCCCGGCGGCGAAGATCAAAAGCGTCTCGCCCCCGTCGAGGCT
CTCGCCGAAGAAATGGTGCAGCGCGGCGCCGATCGCTCCAGCATGGTGATCGCCTACGGCGGCGGCATCGTCACCGACAT
GGGCGGCTTCCTGGCCGCTATCTTCATGCGCGGCATCCCGGTGCTGCAGATCCCGACCACCTTGCTGGCGCAGGTCGATG
CCGCAATCGGCGGCAAGACCGGAGTGAACCTGGTGAGCGGCAAGAACCTGATCGGCAGCTTCCACCAGCCGCTCGCGGTC
CTCACCGACCCGGCCATTCTGGATTCGCTTCCCGAACGCGAGTACCGCGCCGGACTCTGGGAAATCATCAAGGCCGGCAT
CATCCGTGAGGTGGAGCTCTTCGATTACCTGTCCGAATCCCGCGCCGATGTGCTGGCGCGCAAGCCGGAAGCCGTGGACC
ACATCATCGCCGAGAGCGTCCGCATGAAAGCCGAGGTGGTCTCCAGCGACGAACGCGAAGGCGACATGCGCCGCATCCTG
AATTTCGGCCACACCTTCGGACACGCGCTCGAAGCCGAGACCGAATACAAACGCCTGCTGCATGGCGAGGCGGTCGCGTG
GGGTATGCGCGCAGCCATCTATCTCGGCGAGTCCACCGGCTACGTGTCGGCGGAGGACTCGGTCGATATGCTGCAGATGA
TCGAGGACTACGGTCCGATTCCCTCACTCGCCGGCATTCGCGCCGAAAACCTGCTGGCGCGCCTGGTTCACGATAAGAAA
ACGGTACAGGGTAAAGTCCACTTCGTGCTGCCCGTGCGCATCGGCGAAGTGACGGTGGTCTCCGGAATCGAGGAACCGCT
GGTGTTCGAGGCCATGCGGTCCGCCCTCGCATGA

Upstream 100 bases:

>100_bases
TTCGGTCACCGGAAAAATGTAAGTCGCTGAGATGATTGTGTTCTAAAAAGCACGGTGACCTAACTTAGGTCACCATCCCG
CTCCGTGGTACAAAAAGTTC

Downstream 100 bases:

>100_bases
GCGGCGCCAAACCGCTGGGCGCGCGCGATGAGCAGGAGGCGGCACGCTGGGTGCGCGGGATGTTCGGCCGCGTCGCCCAC
CGCTACGACCTCGCCAACCA

Product: 3-dehydroquinate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 357; Mature: 356

Protein sequence:

>357_residues
MPSYLVETPQRCYSAIVERGIIGQTAQYLPPKTGKVFVVTTADVWKHAGAPLKAALAGIPFEILNLPGGEDQKRLAPVEA
LAEEMVQRGADRSSMVIAYGGGIVTDMGGFLAAIFMRGIPVLQIPTTLLAQVDAAIGGKTGVNLVSGKNLIGSFHQPLAV
LTDPAILDSLPEREYRAGLWEIIKAGIIREVELFDYLSESRADVLARKPEAVDHIIAESVRMKAEVVSSDEREGDMRRIL
NFGHTFGHALEAETEYKRLLHGEAVAWGMRAAIYLGESTGYVSAEDSVDMLQMIEDYGPIPSLAGIRAENLLARLVHDKK
TVQGKVHFVLPVRIGEVTVVSGIEEPLVFEAMRSALA

Sequences:

>Translated_357_residues
MPSYLVETPQRCYSAIVERGIIGQTAQYLPPKTGKVFVVTTADVWKHAGAPLKAALAGIPFEILNLPGGEDQKRLAPVEA
LAEEMVQRGADRSSMVIAYGGGIVTDMGGFLAAIFMRGIPVLQIPTTLLAQVDAAIGGKTGVNLVSGKNLIGSFHQPLAV
LTDPAILDSLPEREYRAGLWEIIKAGIIREVELFDYLSESRADVLARKPEAVDHIIAESVRMKAEVVSSDEREGDMRRIL
NFGHTFGHALEAETEYKRLLHGEAVAWGMRAAIYLGESTGYVSAEDSVDMLQMIEDYGPIPSLAGIRAENLLARLVHDKK
TVQGKVHFVLPVRIGEVTVVSGIEEPLVFEAMRSALA
>Mature_356_residues
PSYLVETPQRCYSAIVERGIIGQTAQYLPPKTGKVFVVTTADVWKHAGAPLKAALAGIPFEILNLPGGEDQKRLAPVEAL
AEEMVQRGADRSSMVIAYGGGIVTDMGGFLAAIFMRGIPVLQIPTTLLAQVDAAIGGKTGVNLVSGKNLIGSFHQPLAVL
TDPAILDSLPEREYRAGLWEIIKAGIIREVELFDYLSESRADVLARKPEAVDHIIAESVRMKAEVVSSDEREGDMRRILN
FGHTFGHALEAETEYKRLLHGEAVAWGMRAAIYLGESTGYVSAEDSVDMLQMIEDYGPIPSLAGIRAENLLARLVHDKKT
VQGKVHFVLPVRIGEVTVVSGIEEPLVFEAMRSALA

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; second step. [C]

COG id: COG0337

COG function: function code E; 3-dehydroquinate synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dehydroquinate synthase family

Homologues:

Organism=Escherichia coli, GI1789791, Length=356, Percent_Identity=37.9213483146067, Blast_Score=226, Evalue=2e-60,
Organism=Saccharomyces cerevisiae, GI6320332, Length=257, Percent_Identity=36.9649805447471, Blast_Score=159, Evalue=6e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROB_SOLUE (Q01Q15)

Other databases:

- EMBL:   CP000473
- RefSeq:   YP_828540.1
- ProteinModelPortal:   Q01Q15
- SMR:   Q01Q15
- STRING:   Q01Q15
- GeneID:   4424645
- GenomeReviews:   CP000473_GR
- KEGG:   sus:Acid_7344
- NMPDR:   fig|234267.9.peg.6967
- eggNOG:   COG0337
- HOGENOM:   HBG632303
- OMA:   TERMISD
- PhylomeDB:   Q01Q15
- ProtClustDB:   PRK00002
- GO:   GO:0005737
- HAMAP:   MF_00110
- InterPro:   IPR016303
- InterPro:   IPR002658
- InterPro:   IPR016037
- PANTHER:   PTHR21090:SF1
- PIRSF:   PIRSF001455
- TIGRFAMs:   TIGR01357

Pfam domain/function: PF01761 DHQ_synthase

EC number: =4.2.3.4

Molecular weight: Translated: 38697; Mature: 38566

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSYLVETPQRCYSAIVERGIIGQTAQYLPPKTGKVFVVTTADVWKHAGAPLKAALAGIP
CCCCHHCCHHHHHHHHHHCCCCCCHHHHCCCCCCEEEEEEEHHHHHHCCCCHHHHHHCCC
FEILNLPGGEDQKRLAPVEALAEEMVQRGADRSSMVIAYGGGIVTDMGGFLAAIFMRGIP
CEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHHCCCC
VLQIPTTLLAQVDAAIGGKTGVNLVSGKNLIGSFHQPLAVLTDPAILDSLPEREYRAGLW
EEHHHHHHHHHHHHHCCCCCCCEEECCCHHHHHHHCCHHHHCCCHHHHCCCCHHHHHHHH
EIIKAGIIREVELFDYLSESRADVLARKPEAVDHIIAESVRMKAEVVSSDEREGDMRRIL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
NFGHTFGHALEAETEYKRLLHGEAVAWGMRAAIYLGESTGYVSAEDSVDMLQMIEDYGPI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCCCCCHHHHHHHHHHCCCC
PSLAGIRAENLLARLVHDKKTVQGKVHFVLPVRIGEVTVVSGIEEPLVFEAMRSALA
CCHHCCHHHHHHHHHHHHHHHHCCEEEEEEEEEECCEEEECCCCCHHHHHHHHHHCC
>Mature Secondary Structure 
PSYLVETPQRCYSAIVERGIIGQTAQYLPPKTGKVFVVTTADVWKHAGAPLKAALAGIP
CCCHHCCHHHHHHHHHHCCCCCCHHHHCCCCCCEEEEEEEHHHHHHCCCCHHHHHHCCC
FEILNLPGGEDQKRLAPVEALAEEMVQRGADRSSMVIAYGGGIVTDMGGFLAAIFMRGIP
CEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHHCCCC
VLQIPTTLLAQVDAAIGGKTGVNLVSGKNLIGSFHQPLAVLTDPAILDSLPEREYRAGLW
EEHHHHHHHHHHHHHCCCCCCCEEECCCHHHHHHHCCHHHHCCCHHHHCCCCHHHHHHHH
EIIKAGIIREVELFDYLSESRADVLARKPEAVDHIIAESVRMKAEVVSSDEREGDMRRIL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
NFGHTFGHALEAETEYKRLLHGEAVAWGMRAAIYLGESTGYVSAEDSVDMLQMIEDYGPI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCCCCCHHHHHHHHHHCCCC
PSLAGIRAENLLARLVHDKKTVQGKVHFVLPVRIGEVTVVSGIEEPLVFEAMRSALA
CCHHCCHHHHHHHHHHHHHHHHCCEEEEEEEEEECCEEEECCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA