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The map label for this gene is purQ [H]

Identifier: 116625013

GI number: 116625013

Start: 7450949

End: 7451647

Strand: Direct

Name: purQ [H]

Synonym: Acid_5943

Alternate gene names: 116625013

Gene position: 7450949-7451647 (Clockwise)

Preceding gene: 116625012

Following gene: 116625014

Centisome position: 74.77

GC content: 60.66

Gene sequence:

>699_bases
ATGGGGTTTAGCCTCCCCAAAACAAAAACCATGAAATTCGGCGTCATTGTTTTTCCCGGAAGCAACTGCGATCACGATGC
TTTCTACGCGGTCGCCAACAATCTCGGGCAGCCGGCGGAGTTTATCTGGCACGACTCCCCCTCGCTCGGCGATATCGATG
CAGTGATCCTCCCCGGAGGGTTCTCTTACGGCGATTACCTCCGCTGCGGGGCGATCGCCAAATTTTCACCCGTCATGCAG
GCCGTCAAGAACTTCGCAGCCGCCGGCGGACTGGTACTTGGTGTCTGCAACGGCTTCCAGATTCTTGTGGAAGCCGGATT
GCTGCCCGGCGCGCTGATCCGCAATCGCGACCTGAAATTCATTTGCCGCGAACTGCGGTTGTCGGTGGGCACCACGAACT
CGCCCTTCACGGGCGCCGCACAGAAAGGGCAGGTGCTGCATCTGCCGATCGCGCACGGCGAAGGCTGCTATATCGCCGAC
GAGCGCACCCTCGACGAATTGGAAGCCGAGGACCGCGTGGCTTTCCGCTATATAGACAACGCCAACGGCTCGATGCGCGA
TATCGCCGGCATCCTGAACAAGGAACGCAACGTGATGGGCATGATGCCGCATCCCGAACGGGTCACGGAGCCCTTGATGG
GCGGCACCGACGGGCTGCTGGTCTTCGAATCCATGCTGCGCGCGGCGGTGCACGCATGA

Upstream 100 bases:

>100_bases
ATCGATCGAGTACGCGCGGACAATTCTAGGATAAGTCGCGCAACTCAAACTATGCCGCCATCGCTGTGTCGTGCGATGGC
GTACCGCCGCCTCTGGTAAA

Downstream 100 bases:

>100_bases
GCGGCACGGCCGCCTTCTCACCCGAAATCATCGCCCAGCATCAGTTGACTGACGGCGAGTATCAGAAGATCGTGGACATT
CTGGGCCGCGAACCCAGCTA

Product: phosphoribosylformylglycinamidine synthase subunit I

Products: NA

Alternate protein names: Phosphoribosylformylglycinamidine synthase I; FGAM synthase I [H]

Number of amino acids: Translated: 232; Mature: 231

Protein sequence:

>232_residues
MGFSLPKTKTMKFGVIVFPGSNCDHDAFYAVANNLGQPAEFIWHDSPSLGDIDAVILPGGFSYGDYLRCGAIAKFSPVMQ
AVKNFAAAGGLVLGVCNGFQILVEAGLLPGALIRNRDLKFICRELRLSVGTTNSPFTGAAQKGQVLHLPIAHGEGCYIAD
ERTLDELEAEDRVAFRYIDNANGSMRDIAGILNKERNVMGMMPHPERVTEPLMGGTDGLLVFESMLRAAVHA

Sequences:

>Translated_232_residues
MGFSLPKTKTMKFGVIVFPGSNCDHDAFYAVANNLGQPAEFIWHDSPSLGDIDAVILPGGFSYGDYLRCGAIAKFSPVMQ
AVKNFAAAGGLVLGVCNGFQILVEAGLLPGALIRNRDLKFICRELRLSVGTTNSPFTGAAQKGQVLHLPIAHGEGCYIAD
ERTLDELEAEDRVAFRYIDNANGSMRDIAGILNKERNVMGMMPHPERVTEPLMGGTDGLLVFESMLRAAVHA
>Mature_231_residues
GFSLPKTKTMKFGVIVFPGSNCDHDAFYAVANNLGQPAEFIWHDSPSLGDIDAVILPGGFSYGDYLRCGAIAKFSPVMQA
VKNFAAAGGLVLGVCNGFQILVEAGLLPGALIRNRDLKFICRELRLSVGTTNSPFTGAAQKGQVLHLPIAHGEGCYIADE
RTLDELEAEDRVAFRYIDNANGSMRDIAGILNKERNVMGMMPHPERVTEPLMGGTDGLLVFESMLRAAVHA

Specific function: Unknown

COG id: COG0047

COG function: function code F; Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI48994899, Length=186, Percent_Identity=34.9462365591398, Blast_Score=70, Evalue=9e-14,
Organism=Drosophila melanogaster, GI24582111, Length=193, Percent_Identity=30.0518134715026, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24582109, Length=193, Percent_Identity=30.0518134715026, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI17137292, Length=193, Percent_Identity=30.0518134715026, Blast_Score=77, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR010075 [H]

Pfam domain/function: PF00117 GATase [H]

EC number: =6.3.5.3 [H]

Molecular weight: Translated: 24988; Mature: 24857

Theoretical pI: Translated: 5.93; Mature: 5.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGFSLPKTKTMKFGVIVFPGSNCDHDAFYAVANNLGQPAEFIWHDSPSLGDIDAVILPGG
CCCCCCCCCEEEEEEEEECCCCCCHHHHHHHHHCCCCCCCEEECCCCCCCCCEEEEECCC
FSYGDYLRCGAIAKFSPVMQAVKNFAAAGGLVLGVCNGFQILVEAGLLPGALIRNRDLKF
CCCCCHHHHCCHHHHHHHHHHHHHHHHHCCCEEEHHCCHHEEHHHCCCCCHHHCCCCHHH
ICRELRLSVGTTNSPFTGAAQKGQVLHLPIAHGEGCYIADERTLDELEAEDRVAFRYIDN
HHHHHHHHCCCCCCCCCCCCCCCCEEEEEEECCCCEEEECCCCHHHHCCCCCEEEEEEEC
ANGSMRDIAGILNKERNVMGMMPHPERVTEPLMGGTDGLLVFESMLRAAVHA
CCCCHHHHHHHHHCCCCEEECCCCHHHHHHHHCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
GFSLPKTKTMKFGVIVFPGSNCDHDAFYAVANNLGQPAEFIWHDSPSLGDIDAVILPGG
CCCCCCCCEEEEEEEEECCCCCCHHHHHHHHHCCCCCCCEEECCCCCCCCCEEEEECCC
FSYGDYLRCGAIAKFSPVMQAVKNFAAAGGLVLGVCNGFQILVEAGLLPGALIRNRDLKF
CCCCCHHHHCCHHHHHHHHHHHHHHHHHCCCEEEHHCCHHEEHHHCCCCCHHHCCCCHHH
ICRELRLSVGTTNSPFTGAAQKGQVLHLPIAHGEGCYIADERTLDELEAEDRVAFRYIDN
HHHHHHHHCCCCCCCCCCCCCCCCEEEEEEECCCCEEEECCCCHHHHCCCCCEEEEEEEC
ANGSMRDIAGILNKERNVMGMMPHPERVTEPLMGGTDGLLVFESMLRAAVHA
CCCCHHHHHHHHHCCCCEEECCCCHHHHHHHHCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA