Click here to switch to the map view.

The map label for this gene is yccK [H]

Identifier: 116624908

GI number: 116624908

Start: 7307682

End: 7308674

Strand: Direct

Name: yccK [H]

Synonym: Acid_5834

Alternate gene names: 116624908

Gene position: 7307682-7308674 (Clockwise)

Preceding gene: 116624907

Following gene: 116624909

Centisome position: 73.33

GC content: 60.12

Gene sequence:

>993_bases
ATGCAGAAGCGCAAACTTGGAACCCGCGGTCCGGAGGTCTCCGCGATCGGACTCGGCTGCATGGGAATGAGCTTTGGTTA
TGGCCCGCCCAAAGACAAGCAGGAGATGATTCCGGTTATCCGGGCGGCGGTGGAACGCGGTGTCACGTTCTTCGATACCG
CGGAGGTCTACGGCCCGTTTATCAATGAGGAACTGGTGGGTGAAGCCCTGGCTCCGTTTCGCAAGCAGGTGGTAATCGCG
ACCAAGTTCGGGTTCAACCTGGATCCGAACACGGGCAAACAGGTCGGCCTGAACAGCCGGCCGGAGCACATCAAGCAGGT
AGCCGAGGGCTCGCTCAAGCGGCTCGGGGTCGAGACAATCGATCTTTTCTACCAGCATCGCGTTGACCCGGAGGTGCCGA
TCGAAGATGTGGCGGGGGCGGTGAGGGAATTGATTCAGGAAGGCAAGGTCAAGCACTTCGGGCTTTCCGAAGCAGGAGTG
AAGACGATTCGACGCGCTCACTCCGTGCAGCCGGTGACCGCGCTGCAGAGCGAATACTCGTTGTGGACCAGAGGCCCCGA
GAAGGAGGTGCTGGCGACGGTAGAAGAACTTGGAATTGGTTTCGTTCCGTATAGCCCGCTGGGAAAGGGCTTTCTGACGG
GGAAAATGGACGAGAGCACCAAGCTCGAGAGCACGGATTTCCGCAACATCCTGCCGCGATTCACGCCTGAAGCAATGCGG
GCGAATCGAGCGCTGGTGGATCTGCTGACCAGCATCGGAGAGCGGATGAAGGCGACACCGGCCCAGATCGCAATCGCGTG
GCTGCTTGCCCAAAAGCCGTGGATCGTTCCCATTCCGGGCACCACGAGAGTGGCGCGCCTGGAGGAGAATCTCGGAGCAG
CCAATATCGAACTTACGGCGGCCGATCTCCGGGAAATCGACAGCGCCGCTTCGAAGATCGCGGTGCAGGGAGCTCGATAT
CCCGAGCATATCGAGCAAATGACGGGCCGCTAG

Upstream 100 bases:

>100_bases
GTACGGTGAGCAACAGTGCGAGAGGAACAGGCCATAAATCGTAAGGATCGGGATACCGCACGCGGAGAGCCCGGCCCTAA
CCTGGAGATGAGGAGAAGCA

Downstream 100 bases:

>100_bases
ATTTCCGATGGCGCATAAACTACTGAAAGGAGCATTTATACATGTATAAGGCGAAGGCTTATTCGGCCGGCAGCGCGACC
TCGCCGCTGGCTTCCACGAC

Product: aldo/keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 330; Mature: 330

Protein sequence:

>330_residues
MQKRKLGTRGPEVSAIGLGCMGMSFGYGPPKDKQEMIPVIRAAVERGVTFFDTAEVYGPFINEELVGEALAPFRKQVVIA
TKFGFNLDPNTGKQVGLNSRPEHIKQVAEGSLKRLGVETIDLFYQHRVDPEVPIEDVAGAVRELIQEGKVKHFGLSEAGV
KTIRRAHSVQPVTALQSEYSLWTRGPEKEVLATVEELGIGFVPYSPLGKGFLTGKMDESTKLESTDFRNILPRFTPEAMR
ANRALVDLLTSIGERMKATPAQIAIAWLLAQKPWIVPIPGTTRVARLEENLGAANIELTAADLREIDSAASKIAVQGARY
PEHIEQMTGR

Sequences:

>Translated_330_residues
MQKRKLGTRGPEVSAIGLGCMGMSFGYGPPKDKQEMIPVIRAAVERGVTFFDTAEVYGPFINEELVGEALAPFRKQVVIA
TKFGFNLDPNTGKQVGLNSRPEHIKQVAEGSLKRLGVETIDLFYQHRVDPEVPIEDVAGAVRELIQEGKVKHFGLSEAGV
KTIRRAHSVQPVTALQSEYSLWTRGPEKEVLATVEELGIGFVPYSPLGKGFLTGKMDESTKLESTDFRNILPRFTPEAMR
ANRALVDLLTSIGERMKATPAQIAIAWLLAQKPWIVPIPGTTRVARLEENLGAANIELTAADLREIDSAASKIAVQGARY
PEHIEQMTGR
>Mature_330_residues
MQKRKLGTRGPEVSAIGLGCMGMSFGYGPPKDKQEMIPVIRAAVERGVTFFDTAEVYGPFINEELVGEALAPFRKQVVIA
TKFGFNLDPNTGKQVGLNSRPEHIKQVAEGSLKRLGVETIDLFYQHRVDPEVPIEDVAGAVRELIQEGKVKHFGLSEAGV
KTIRRAHSVQPVTALQSEYSLWTRGPEKEVLATVEELGIGFVPYSPLGKGFLTGKMDESTKLESTDFRNILPRFTPEAMR
ANRALVDLLTSIGERMKATPAQIAIAWLLAQKPWIVPIPGTTRVARLEENLGAANIELTAADLREIDSAASKIAVQGARY
PEHIEQMTGR

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436964, Length=324, Percent_Identity=30.2469135802469, Blast_Score=123, Evalue=3e-28,
Organism=Homo sapiens, GI27436966, Length=324, Percent_Identity=30.2469135802469, Blast_Score=122, Evalue=6e-28,
Organism=Homo sapiens, GI27436962, Length=324, Percent_Identity=30.2469135802469, Blast_Score=122, Evalue=6e-28,
Organism=Homo sapiens, GI27436969, Length=324, Percent_Identity=29.0123456790123, Blast_Score=119, Evalue=4e-27,
Organism=Homo sapiens, GI4504825, Length=321, Percent_Identity=28.9719626168224, Blast_Score=119, Evalue=5e-27,
Organism=Homo sapiens, GI27436971, Length=323, Percent_Identity=29.7213622291022, Blast_Score=118, Evalue=7e-27,
Organism=Homo sapiens, GI223718702, Length=226, Percent_Identity=32.7433628318584, Blast_Score=92, Evalue=7e-19,
Organism=Homo sapiens, GI41327764, Length=233, Percent_Identity=32.618025751073, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI41152114, Length=213, Percent_Identity=30.9859154929577, Blast_Score=82, Evalue=5e-16,
Organism=Escherichia coli, GI87081735, Length=322, Percent_Identity=31.055900621118, Blast_Score=146, Evalue=2e-36,
Organism=Escherichia coli, GI1789375, Length=326, Percent_Identity=30.3680981595092, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI1787674, Length=311, Percent_Identity=30.8681672025724, Blast_Score=132, Evalue=4e-32,
Organism=Escherichia coli, GI1788070, Length=340, Percent_Identity=30.2941176470588, Blast_Score=124, Evalue=9e-30,
Organism=Escherichia coli, GI1788081, Length=313, Percent_Identity=24.9201277955272, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI1789199, Length=348, Percent_Identity=26.4367816091954, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI48994888, Length=322, Percent_Identity=26.0869565217391, Blast_Score=81, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17564128, Length=331, Percent_Identity=22.3564954682779, Blast_Score=71, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI17566692, Length=310, Percent_Identity=24.1935483870968, Blast_Score=64, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6325169, Length=336, Percent_Identity=26.7857142857143, Blast_Score=122, Evalue=1e-28,
Organism=Saccharomyces cerevisiae, GI6325384, Length=339, Percent_Identity=29.4985250737463, Blast_Score=114, Evalue=3e-26,
Organism=Saccharomyces cerevisiae, GI6323998, Length=320, Percent_Identity=25.9375, Blast_Score=97, Evalue=4e-21,
Organism=Saccharomyces cerevisiae, GI6319958, Length=292, Percent_Identity=25, Blast_Score=92, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6322615, Length=250, Percent_Identity=25.6, Blast_Score=83, Evalue=5e-17,
Organism=Saccharomyces cerevisiae, GI6319951, Length=293, Percent_Identity=24.2320819112628, Blast_Score=83, Evalue=7e-17,
Organism=Drosophila melanogaster, GI24640980, Length=327, Percent_Identity=23.8532110091743, Blast_Score=88, Evalue=8e-18,
Organism=Drosophila melanogaster, GI45549126, Length=324, Percent_Identity=25, Blast_Score=88, Evalue=9e-18,
Organism=Drosophila melanogaster, GI24646159, Length=223, Percent_Identity=27.8026905829596, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24646155, Length=170, Percent_Identity=29.4117647058824, Blast_Score=69, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 36215; Mature: 36215

Theoretical pI: Translated: 7.71; Mature: 7.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKRKLGTRGPEVSAIGLGCMGMSFGYGPPKDKQEMIPVIRAAVERGVTFFDTAEVYGPF
CCCCCCCCCCCCCEEEEHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEHHHHHCCC
INEELVGEALAPFRKQVVIATKFGFNLDPNTGKQVGLNSRPEHIKQVAEGSLKRLGVETI
CCHHHHHHHHHHHHHEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
DLFYQHRVDPEVPIEDVAGAVRELIQEGKVKHFGLSEAGVKTIRRAHSVQPVTALQSEYS
HHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHH
LWTRGPEKEVLATVEELGIGFVPYSPLGKGFLTGKMDESTKLESTDFRNILPRFTPEAMR
HHCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCHHHHH
ANRALVDLLTSIGERMKATPAQIAIAWLLAQKPWIVPIPGTTRVARLEENLGAANIELTA
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCEEEECCCCHHHHHHHHCCCCCCEEEEH
ADLREIDSAASKIAVQGARYPEHIEQMTGR
HHHHHHHHHHHHHHHCCCCCHHHHHHHHCC
>Mature Secondary Structure
MQKRKLGTRGPEVSAIGLGCMGMSFGYGPPKDKQEMIPVIRAAVERGVTFFDTAEVYGPF
CCCCCCCCCCCCCEEEEHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEHHHHHCCC
INEELVGEALAPFRKQVVIATKFGFNLDPNTGKQVGLNSRPEHIKQVAEGSLKRLGVETI
CCHHHHHHHHHHHHHEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
DLFYQHRVDPEVPIEDVAGAVRELIQEGKVKHFGLSEAGVKTIRRAHSVQPVTALQSEYS
HHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHH
LWTRGPEKEVLATVEELGIGFVPYSPLGKGFLTGKMDESTKLESTDFRNILPRFTPEAMR
HHCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCHHHHH
ANRALVDLLTSIGERMKATPAQIAIAWLLAQKPWIVPIPGTTRVARLEENLGAANIELTA
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCEEEECCCCHHHHHHHHCCCCCCEEEEH
ADLREIDSAASKIAVQGARYPEHIEQMTGR
HHHHHHHHHHHHHHHCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9274031; 9384377; 9106203 [H]