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The map label for this gene is 116623499

Identifier: 116623499

GI number: 116623499

Start: 5578526

End: 5579590

Strand: Reverse

Name: 116623499

Synonym: Acid_4409

Alternate gene names: NA

Gene position: 5579590-5578526 (Counterclockwise)

Preceding gene: 116623500

Following gene: 116623498

Centisome position: 55.99

GC content: 64.88

Gene sequence:

>1065_bases
ATGCAGTCCAAACCTCGCCTGGCGTTCTTTGAGCGCTATCTCTCGCTGTGGGTAGCGCTCTGCATGGCGGCCGGAATTCT
GCTGGGCAGAAGCTGGCCCTCGGCGGTCCGGTCCGTGCGCTCGCTCGAGTTCGGGCGCGGGAGCCAGATCAACGTCGCCA
TCGCGGTGCTGATCTGGCTCATGATCACGCCGATGATGATGAAGGTCGATTTCACCGCGATCCGGGACGTGGGGCGCAGG
CCCGCCGGGTTGGCGGTCACGCTGGCGGTGAACTGGCTGGTCAAGCCGTTTTCGATGGCGCTGCTCGCATGGCTCTTTTT
CCGCATCGTCTTTTCGCCCTGGGTCAGCGGCGCGGAGGCCGATCAGTATATCGCGGGCTGCATCGTGCTGGCTGCCGCGC
CGTGTACCGCGATGGTCTTCGTCTGGAGCCACTTGACGGGCGGCGACGCGGCGTACACGCTGGTGCAGGTGGCGGTCAAC
GACCTGATCATGCTCGTGCTGTTCGTCCCCATTGTACGGCTCCTGGTTACCGGCGCATCTTCGCTCACGGTCCCTTTCGG
CGTCCTGCTGTGGTCGGTGACGGTCTTCATCGTGATCCCGCTGGCCGCGGGGACGCTGCTGCGGACGCGGCTGTTGGCGG
CTCATGGGCGCCCGTGGTTCGAAGGTACGCTGATGCCCCGTTTTGCGCCGATCACGATCGGCGCCCTACTCGCGACGCTG
GTGTTGATCTTCGCTTTTCAGGCGGACAACATCACAGGCCGGTTCGGCCACGTGCTGCTGATCGCGGTGCCGATTACGCT
GCAGGTATATTTCAACGCTTCGCTGGCCTACGGGCTGATGAAGTGGTTGAAAGTGGAGCACGCAGTGGCGGCGCCCGGCG
CGCTGATCGGCGCCAGCAATTTCTTCGAACTGGCGGTAGCGACGGCGATCGCGCTGTTCGGGCCCGATTCGGGCGCGGCG
CTGGCGACGGTGGTCGGCGTATTGGTCGAGGTGCCGGTGATGCTCTCGGTGTGCGGCGTCTGCAATCGAACCGGTCACTG
GTTCCCCGGAAAGCAGGAGGCCTGA

Upstream 100 bases:

>100_bases
GTCGCGCCGCTGGTGGACGGAAAGTTCTTCAGCGCTTTCATTCGCGCGCGCAAGCCGGCCGCGGCCTGCTGCGGCCCCGC
CTGCTGTTCGTAGGGCAAAT

Downstream 100 bases:

>100_bases
GTGCCCAGCGTGTTGATCCTATGTACCGGAAACTCGGCGCGCTCGCAGATGGCCGAGGGCCTGTTCCGCCAGGAGAGCGG
CGGGACGTGGGAAGTCTGCT

Product: bile acid:sodium symporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 354; Mature: 354

Protein sequence:

>354_residues
MQSKPRLAFFERYLSLWVALCMAAGILLGRSWPSAVRSVRSLEFGRGSQINVAIAVLIWLMITPMMMKVDFTAIRDVGRR
PAGLAVTLAVNWLVKPFSMALLAWLFFRIVFSPWVSGAEADQYIAGCIVLAAAPCTAMVFVWSHLTGGDAAYTLVQVAVN
DLIMLVLFVPIVRLLVTGASSLTVPFGVLLWSVTVFIVIPLAAGTLLRTRLLAAHGRPWFEGTLMPRFAPITIGALLATL
VLIFAFQADNITGRFGHVLLIAVPITLQVYFNASLAYGLMKWLKVEHAVAAPGALIGASNFFELAVATAIALFGPDSGAA
LATVVGVLVEVPVMLSVCGVCNRTGHWFPGKQEA

Sequences:

>Translated_354_residues
MQSKPRLAFFERYLSLWVALCMAAGILLGRSWPSAVRSVRSLEFGRGSQINVAIAVLIWLMITPMMMKVDFTAIRDVGRR
PAGLAVTLAVNWLVKPFSMALLAWLFFRIVFSPWVSGAEADQYIAGCIVLAAAPCTAMVFVWSHLTGGDAAYTLVQVAVN
DLIMLVLFVPIVRLLVTGASSLTVPFGVLLWSVTVFIVIPLAAGTLLRTRLLAAHGRPWFEGTLMPRFAPITIGALLATL
VLIFAFQADNITGRFGHVLLIAVPITLQVYFNASLAYGLMKWLKVEHAVAAPGALIGASNFFELAVATAIALFGPDSGAA
LATVVGVLVEVPVMLSVCGVCNRTGHWFPGKQEA
>Mature_354_residues
MQSKPRLAFFERYLSLWVALCMAAGILLGRSWPSAVRSVRSLEFGRGSQINVAIAVLIWLMITPMMMKVDFTAIRDVGRR
PAGLAVTLAVNWLVKPFSMALLAWLFFRIVFSPWVSGAEADQYIAGCIVLAAAPCTAMVFVWSHLTGGDAAYTLVQVAVN
DLIMLVLFVPIVRLLVTGASSLTVPFGVLLWSVTVFIVIPLAAGTLLRTRLLAAHGRPWFEGTLMPRFAPITIGALLATL
VLIFAFQADNITGRFGHVLLIAVPITLQVYFNASLAYGLMKWLKVEHAVAAPGALIGASNFFELAVATAIALFGPDSGAA
LATVVGVLVEVPVMLSVCGVCNRTGHWFPGKQEA

Specific function: Unknown

COG id: COG0798

COG function: function code P; Arsenite efflux pump ACR3 and related permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ACR3 family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6325459, Length=323, Percent_Identity=26.9349845201238, Blast_Score=97, Evalue=3e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004706
- InterPro:   IPR002657 [H]

Pfam domain/function: PF01758 SBF [H]

EC number: NA

Molecular weight: Translated: 38086; Mature: 38086

Theoretical pI: Translated: 9.81; Mature: 9.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQSKPRLAFFERYLSLWVALCMAAGILLGRSWPSAVRSVRSLEFGRGSQINVAIAVLIWL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHH
MITPMMMKVDFTAIRDVGRRPAGLAVTLAVNWLVKPFSMALLAWLFFRIVFSPWVSGAEA
HHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
DQYIAGCIVLAAAPCTAMVFVWSHLTGGDAAYTLVQVAVNDLIMLVLFVPIVRLLVTGAS
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
SLTVPFGVLLWSVTVFIVIPLAAGTLLRTRLLAAHGRPWFEGTLMPRFAPITIGALLATL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHH
VLIFAFQADNITGRFGHVLLIAVPITLQVYFNASLAYGLMKWLKVEHAVAAPGALIGASN
HHHHHHCCCCCCCHHHHEEEEEEEHEEEEEECHHHHHHHHHHHHHHHHHCCCCHHCCCCH
FFELAVATAIALFGPDSGAALATVVGVLVEVPVMLSVCGVCNRTGHWFPGKQEA
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MQSKPRLAFFERYLSLWVALCMAAGILLGRSWPSAVRSVRSLEFGRGSQINVAIAVLIWL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHH
MITPMMMKVDFTAIRDVGRRPAGLAVTLAVNWLVKPFSMALLAWLFFRIVFSPWVSGAEA
HHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
DQYIAGCIVLAAAPCTAMVFVWSHLTGGDAAYTLVQVAVNDLIMLVLFVPIVRLLVTGAS
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
SLTVPFGVLLWSVTVFIVIPLAAGTLLRTRLLAAHGRPWFEGTLMPRFAPITIGALLATL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHH
VLIFAFQADNITGRFGHVLLIAVPITLQVYFNASLAYGLMKWLKVEHAVAAPGALIGASN
HHHHHHCCCCCCCHHHHEEEEEEEHEEEEEECHHHHHHHHHHHHHHHHHCCCCHHCCCCH
FFELAVATAIALFGPDSGAALATVVGVLVEVPVMLSVCGVCNRTGHWFPGKQEA
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]