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The map label for this gene is arsC [H]

Identifier: 116623498

GI number: 116623498

Start: 5578130

End: 5578525

Strand: Reverse

Name: arsC [H]

Synonym: Acid_4408

Alternate gene names: 116623498

Gene position: 5578525-5578130 (Counterclockwise)

Preceding gene: 116623499

Following gene: 116623496

Centisome position: 55.98

GC content: 58.84

Gene sequence:

>396_bases
GTGCCCAGCGTGTTGATCCTATGTACCGGAAACTCGGCGCGCTCGCAGATGGCCGAGGGCCTGTTCCGCCAGGAGAGCGG
CGGGACGTGGGAAGTCTGCTCGGCGGGAACCCGCCCCACCAAGGTGCGCCCGGAGGCGATTGTGGCGATGCAGGAGATTG
GCATCGACATTTCCAAGCACTGGTCGAAATCGGTGGACGAGTTCGCGGGCAGGGAATTCGACTACGTGATTACGGTGTGC
GATCACGCTAATGCAATTTGTCCGGTGTTTCCAGGAAGGACACATCGATTGCACTGGCCATTCGAGGATCCGGCCGGGAT
CGAAGATTTTCGACGAGTACGTGACGAGATTCACTCCAAGGTTAAGACGGTGCTGGCAAGTGTGATCGCTCCCTAA

Upstream 100 bases:

>100_bases
GACGGTGGTCGGCGTATTGGTCGAGGTGCCGGTGATGCTCTCGGTGTGCGGCGTCTGCAATCGAACCGGTCACTGGTTCC
CCGGAAAGCAGGAGGCCTGA

Downstream 100 bases:

>100_bases
CGTGTCGCGGCTCGGATTGAACCGCGACCGTCACGGAGTATACGCGCTCGACAGGGCGTGCGCCTGGACGTGATGATCGC
AGCGCACGAGGATTCGGCCG

Product: protein tyrosine phosphatase

Products: NA

Alternate protein names: Arsenate reductase; Arsenical pump modifier; Low molecular weight protein-tyrosine-phosphatase [H]

Number of amino acids: Translated: 131; Mature: 130

Protein sequence:

>131_residues
MPSVLILCTGNSARSQMAEGLFRQESGGTWEVCSAGTRPTKVRPEAIVAMQEIGIDISKHWSKSVDEFAGREFDYVITVC
DHANAICPVFPGRTHRLHWPFEDPAGIEDFRRVRDEIHSKVKTVLASVIAP

Sequences:

>Translated_131_residues
MPSVLILCTGNSARSQMAEGLFRQESGGTWEVCSAGTRPTKVRPEAIVAMQEIGIDISKHWSKSVDEFAGREFDYVITVC
DHANAICPVFPGRTHRLHWPFEDPAGIEDFRRVRDEIHSKVKTVLASVIAP
>Mature_130_residues
PSVLILCTGNSARSQMAEGLFRQESGGTWEVCSAGTRPTKVRPEAIVAMQEIGIDISKHWSKSVDEFAGREFDYVITVCD
HANAICPVFPGRTHRLHWPFEDPAGIEDFRRVRDEIHSKVKTVLASVIAP

Specific function: Reduces arsenate [As(V)] to arsenite [As(III)] and dephosphorylates tyrosine phosphorylated proteins, low-MW aryl phosphates and natural and synthetic acyl phosphates. Could switch between different functions in different circumstances [H]

COG id: COG0394

COG function: function code T; Protein-tyrosine-phosphatase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the low molecular weight phosphotyrosine protein phosphatase superfamily. ArsC family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014064
- InterPro:   IPR017867 [H]

Pfam domain/function: PF01451 LMWPc [H]

EC number: =3.1.3.48 [H]

Molecular weight: Translated: 14565; Mature: 14434

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSVLILCTGNSARSQMAEGLFRQESGGTWEVCSAGTRPTKVRPEAIVAMQEIGIDISKH
CCCEEEEECCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHHHHCCCHHHH
WSKSVDEFAGREFDYVITVCDHANAICPVFPGRTHRLHWPFEDPAGIEDFRRVRDEIHSK
HHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCEEECCCCCCCCHHHHHHHHHHHHHH
VKTVLASVIAP
HHHHHHHHHCC
>Mature Secondary Structure 
PSVLILCTGNSARSQMAEGLFRQESGGTWEVCSAGTRPTKVRPEAIVAMQEIGIDISKH
CCEEEEECCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHHHHCCCHHHH
WSKSVDEFAGREFDYVITVCDHANAICPVFPGRTHRLHWPFEDPAGIEDFRRVRDEIHSK
HHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCEEECCCCCCCCHHHHHHHHHHHHHH
VKTVLASVIAP
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]