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The map label for this gene is 116622928

Identifier: 116622928

GI number: 116622928

Start: 4861964

End: 4862902

Strand: Reverse

Name: 116622928

Synonym: Acid_3830

Alternate gene names: NA

Gene position: 4862902-4861964 (Counterclockwise)

Preceding gene: 116622929

Following gene: 116622926

Centisome position: 48.8

GC content: 60.06

Gene sequence:

>939_bases
ATGCGGAAACCCGGCTTCGACCCTGGGCTGACCCAGCAATACACCGGTAATGTCCGGCGGATCGTTGAAAAGGACGGGCG
TTTTAATGTGCGCCGCCGCGGCGGCAACTGGCACGACGTTCATCCCTATTTGCACCTGATCAATATGGGATGGCCGCAGT
TTCTGGGATGGCTGATTCTGGGCTACCTGGTGACCAACACGATTTTCGCGGCGGTCTTCTATGAGTTGGGGCCGGGGCAG
CTTGCCATGTCCGATGGAATGATGCTGGGCCAGTTTCTGGAGTGTTTCTTTTTTAGCGCGCACACCTTGACCACGGTGGG
CTACGGCAGCATCGCGCCCATCGGGCTGGGAGCCAACGTGGTGGCGTCGATCGAGTCGCTGGTCGGCGTGCTGTTCTTTG
CGGTGGCCACCGGATTGCTCTTCGGGCGCGTGTCGCGGCCCTCGGCCAAGATCGGCTACAGCGAAAATATACTGATGGCG
CCGTACCAGGACATCACGAGCCTGCAGTGCCGGGTGGTAAACCGGCGCGCCAACGAATTGATGGAGCTTGAGGCGCGCGT
GCTGCTGATGACGGTGGACATGGTGAACGGGCAGCCGCAGCGAAGATATCAGCAGCTCAAGCTGGAGCGCGAACAGTTGA
CGTTCTTACCGCTGACCTGGACCGTGGTGCACCCGATCGACAACGAGAGTCCGCTGTGGGGCGTCACCCCAGCGGATTTC
GAGCGGCGGCAGACGGAGATCCTGGTGATGATCAAGGCGTATGACGACACCTTCAGCCACACCGTGTTCTCGCGATACTC
CTACCGCTTCGATGAGGTGATTTGGAACATGCGTTTTGCGCCCGCGTTCACGGTAGACGACGAGGGCGAACTCGTACTCG
ATTTGCAGAAGGTGGGCCAGTTCAAGGAAAACGAGGGCCCACCCGAGTTGGCCAGCTAG

Upstream 100 bases:

>100_bases
TGTACATCGAAAACGGACAGGAAGTGCGAAGCGAGCCGCTGGACCTGGTGGGAAGTCCGGAGGCACTGGTGCGGGGCTGG
CTGGCGTAAGATTTGAACTT

Downstream 100 bases:

>100_bases
GCTACTTCTTCTTTTTTGCGCCCATCGGCGGAGGGGCCGGCTGGCTGGCCGGCGGAATGACATTGTTCATGCGCGCGTAC
ACCACCATTTGGCCGTAGTG

Product: Ion transport 2 domain-containing protein

Products: NA

Alternate protein names: Ion Transport 2 Domain-Containing Protein; K+ Channel Inward Rectifier; Inward Rectifier Potassium Channel; Inward Rectifier Potassium Channel Protein; Inward Rectifier Potassium Channel Superfamily; TrkA-N Family Protein; ATP-Sensitive Potassium Transporter; Potassium Channel Protein; Inward Rectifier Potassium Channel Irk; ATP-Sensitive Inward Rectifier Potassium Channel; K+ Channel Inward Rectifier Protein; K+ Channel Protein; ATP-Sensitive Potassium Channel Protein; Ion Transport 2 Domain Protein

Number of amino acids: Translated: 312; Mature: 312

Protein sequence:

>312_residues
MRKPGFDPGLTQQYTGNVRRIVEKDGRFNVRRRGGNWHDVHPYLHLINMGWPQFLGWLILGYLVTNTIFAAVFYELGPGQ
LAMSDGMMLGQFLECFFFSAHTLTTVGYGSIAPIGLGANVVASIESLVGVLFFAVATGLLFGRVSRPSAKIGYSENILMA
PYQDITSLQCRVVNRRANELMELEARVLLMTVDMVNGQPQRRYQQLKLEREQLTFLPLTWTVVHPIDNESPLWGVTPADF
ERRQTEILVMIKAYDDTFSHTVFSRYSYRFDEVIWNMRFAPAFTVDDEGELVLDLQKVGQFKENEGPPELAS

Sequences:

>Translated_312_residues
MRKPGFDPGLTQQYTGNVRRIVEKDGRFNVRRRGGNWHDVHPYLHLINMGWPQFLGWLILGYLVTNTIFAAVFYELGPGQ
LAMSDGMMLGQFLECFFFSAHTLTTVGYGSIAPIGLGANVVASIESLVGVLFFAVATGLLFGRVSRPSAKIGYSENILMA
PYQDITSLQCRVVNRRANELMELEARVLLMTVDMVNGQPQRRYQQLKLEREQLTFLPLTWTVVHPIDNESPLWGVTPADF
ERRQTEILVMIKAYDDTFSHTVFSRYSYRFDEVIWNMRFAPAFTVDDEGELVLDLQKVGQFKENEGPPELAS
>Mature_312_residues
MRKPGFDPGLTQQYTGNVRRIVEKDGRFNVRRRGGNWHDVHPYLHLINMGWPQFLGWLILGYLVTNTIFAAVFYELGPGQ
LAMSDGMMLGQFLECFFFSAHTLTTVGYGSIAPIGLGANVVASIESLVGVLFFAVATGLLFGRVSRPSAKIGYSENILMA
PYQDITSLQCRVVNRRANELMELEARVLLMTVDMVNGQPQRRYQQLKLEREQLTFLPLTWTVVHPIDNESPLWGVTPADF
ERRQTEILVMIKAYDDTFSHTVFSRYSYRFDEVIWNMRFAPAFTVDDEGELVLDLQKVGQFKENEGPPELAS

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI25121970, Length=301, Percent_Identity=26.578073089701, Blast_Score=93, Evalue=4e-19,
Organism=Homo sapiens, GI303227939, Length=300, Percent_Identity=24, Blast_Score=86, Evalue=6e-17,
Organism=Homo sapiens, GI4504835, Length=305, Percent_Identity=23.6065573770492, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI4504843, Length=298, Percent_Identity=24.1610738255034, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI23110982, Length=303, Percent_Identity=24.4224422442244, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI4504839, Length=319, Percent_Identity=25.0783699059561, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI62388888, Length=297, Percent_Identity=23.5690235690236, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI25777640, Length=315, Percent_Identity=22.8571428571429, Blast_Score=79, Evalue=6e-15,
Organism=Homo sapiens, GI25777638, Length=315, Percent_Identity=22.8571428571429, Blast_Score=79, Evalue=6e-15,
Organism=Homo sapiens, GI21361127, Length=315, Percent_Identity=22.8571428571429, Blast_Score=79, Evalue=6e-15,
Organism=Homo sapiens, GI25777635, Length=306, Percent_Identity=25.1633986928105, Blast_Score=78, Evalue=8e-15,
Organism=Homo sapiens, GI7019439, Length=306, Percent_Identity=25.1633986928105, Blast_Score=78, Evalue=8e-15,
Organism=Homo sapiens, GI24797141, Length=300, Percent_Identity=23, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI4826798, Length=240, Percent_Identity=25.8333333333333, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI23110984, Length=240, Percent_Identity=25.8333333333333, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI239751249, Length=303, Percent_Identity=22.7722772277228, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI310117729, Length=303, Percent_Identity=22.7722772277228, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI8923823, Length=318, Percent_Identity=26.1006289308176, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI25777630, Length=318, Percent_Identity=26.1006289308176, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI25777628, Length=318, Percent_Identity=26.1006289308176, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI24497471, Length=318, Percent_Identity=24.2138364779874, Blast_Score=73, Evalue=4e-13,
Organism=Homo sapiens, GI148539892, Length=318, Percent_Identity=24.2138364779874, Blast_Score=73, Evalue=4e-13,
Organism=Homo sapiens, GI24497467, Length=318, Percent_Identity=24.2138364779874, Blast_Score=73, Evalue=4e-13,
Organism=Homo sapiens, GI24497473, Length=318, Percent_Identity=24.2138364779874, Blast_Score=73, Evalue=4e-13,
Organism=Homo sapiens, GI4504837, Length=318, Percent_Identity=24.2138364779874, Blast_Score=73, Evalue=4e-13,
Organism=Homo sapiens, GI25121966, Length=337, Percent_Identity=23.1454005934718, Blast_Score=70, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17568583, Length=304, Percent_Identity=23.0263157894737, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17568581, Length=285, Percent_Identity=23.5087719298246, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI281362353, Length=218, Percent_Identity=25.6880733944954, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24649234, Length=218, Percent_Identity=25.6880733944954, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI161078534, Length=218, Percent_Identity=25.6880733944954, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24649327, Length=311, Percent_Identity=24.1157556270096, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24649329, Length=294, Percent_Identity=23.469387755102, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI281362366, Length=294, Percent_Identity=24.1496598639456, Blast_Score=69, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 35457; Mature: 35457

Theoretical pI: Translated: 5.97; Mature: 5.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKPGFDPGLTQQYTGNVRRIVEKDGRFNVRRRGGNWHDVHPYLHLINMGWPQFLGWLIL
CCCCCCCCCCCHHHCCHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHCCHHHHHHHHHH
GYLVTNTIFAAVFYELGPGQLAMSDGMMLGQFLECFFFSAHTLTTVGYGSIAPIGLGANV
HHHHHHHHHHHHHHHCCCCCEECCCCHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCHHH
VASIESLVGVLFFAVATGLLFGRVSRPSAKIGYSENILMAPYQDITSLQCRVVNRRANEL
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHH
MELEARVLLMTVDMVNGQPQRRYQQLKLEREQLTFLPLTWTVVHPIDNESPLWGVTPADF
HHHHHEEEEEEEEHHCCCHHHHHHHHHHHHHHEEEEEEEEEEEECCCCCCCCCCCCCCHH
ERRQTEILVMIKAYDDTFSHTVFSRYSYRFDEVIWNMRFAPAFTVDDEGELVLDLQKVGQ
HCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCEEEEHHHHCC
FKENEGPPELAS
CCCCCCCCCCCC
>Mature Secondary Structure
MRKPGFDPGLTQQYTGNVRRIVEKDGRFNVRRRGGNWHDVHPYLHLINMGWPQFLGWLIL
CCCCCCCCCCCHHHCCHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHCCHHHHHHHHHH
GYLVTNTIFAAVFYELGPGQLAMSDGMMLGQFLECFFFSAHTLTTVGYGSIAPIGLGANV
HHHHHHHHHHHHHHHCCCCCEECCCCHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCHHH
VASIESLVGVLFFAVATGLLFGRVSRPSAKIGYSENILMAPYQDITSLQCRVVNRRANEL
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHH
MELEARVLLMTVDMVNGQPQRRYQQLKLEREQLTFLPLTWTVVHPIDNESPLWGVTPADF
HHHHHEEEEEEEEHHCCCHHHHHHHHHHHHHHEEEEEEEEEEEECCCCCCCCCCCCCCHH
ERRQTEILVMIKAYDDTFSHTVFSRYSYRFDEVIWNMRFAPAFTVDDEGELVLDLQKVGQ
HCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCEEEEHHHHCC
FKENEGPPELAS
CCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA